• Federico Rojo Todo
  • Juan Madoz Gúrpide

Research Staff

  • Cristina Chamizo García
  • Paula González Alonso
  • Ester Martín Aparicio
  • Sandra Zazo Hernández
  • Alicia Cazorla Jiménez
  • María Jesús Fernández Aceñero
  • Rebeca Manso Alonso
  • Luis Requena Caballero
  • María Socorro Rodríguez Pinilla
  • Carlos Santonja Garriga

Main lines of research

Biomarkers in Cancer Group

The Biomarkers in Cancer group of the IIS-FJD focuses on basic and translational research, and is led by Dr. Federico Rojo. The group consists of a multidisciplinary team, coordinated by Dr. Juan Madoz, formed by various professional and contract staff including pathologists, molecular biologists, laboratory technicians, and PhD students.

Our group carries out its research objectives through its own research projects, intra- and inter-institutional collaborations, participation in international initiatives, studies carried out in conjunction with other groups and businesses, and educational activities.

One of the key research areas of the group is breast cancer, specifically the identification and validation of new predictive biomarkers associated with drug response and the search for mechanisms underlying treatment resistance. The aim is to improve the treatment of breast cancer through preclinical research using in vitro, in vivo, and ex vivo models, and by studying biomarkers of treatment response and the pharmacodynamics of treatment, particularly in targeted therapies. The group also maintains lines of translational research and collaborations focusing on other tumor types, including melanoma and tumors of the colon, head and neck, and lung.

The initial research of the Biomarkers in Cancer group is conducted using physiological platforms and models, including our extensive collection of breast tumor cell lines, in vivo models, ex vivo cell models, collections of primary tumors with clinical follow-up, and pluripotent cell systems. In general, the hypotheses generated in in vitro models are subsequently studied in murine models, and finally, using an approach unique to our group, validated in clinical samples. These samples are stored in the biobank of the FJD, the management of which is overseen by our group. This variety of platforms provides a unique opportunity for target validation and the monitoring of prognostic and predictive markers, and for the discovery of genes involved in the molecular processes underlying the treatment response.

Currently, the Biomarkers in Cancer group is primarily involved in a project to identify new mechanisms of resistance to breast cancer treatment with anti-HER2 therapeutic antibodies. This study is being conducted in collaboration with 2 other Spanish groups. We have several other ongoing collaborations with other IIS-FJD groups, national and foreign centers (within the framework of European projects), and enterprises, and as part of national initiatives for the study of specific pathologies (GEICAM).

Publications (2014)

Total number of Publications

Nº of Publications with IF

Accumulated IF



Nº of Publications (Q1)

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Molina-Ruiz AM, Cerroni L, Kutzner H, Requena L.Cutaneous deposits.Am J Dermatopathol. 2014 Jan;36(1):1-48. doi: 10.1097/DAD.0b013e3182740122. Review..PubMed PMID:23249837


Mollejo M, Menárguez J, Guisado-Vasco P, Bento L, Algara P, Montes-Moreno S, Rodriguez-Pinilla MS, Cruz MA, Casado F, Montalbán C, Piris MA.Hepatitis C virus-related lymphoproliferative disorders encompass a broader clinical and morphological spectrum than previously recognized: a clinicopathological study.Mod Pathol. 2014 Feb;27(2):281-93. doi: 10.1038/modpathol.2013.120. Epub 2013 Aug 9..PubMed PMID:23929267


Concepción Garrido M, Requena L, Kutzner H, Ortiz P, Pérez-Gómez B, Rodriguez-Peralto JL.Desmoplastic melanoma: expression of epithelial-mesenchymal transition-related proteins.Am J Dermatopathol. 2014 Mar;36(3):238-42. doi: 10.1097/DAD.0b013e3182987441..PubMed PMID:23974224


Cañadas I, Rojo F, Taus A, Arpí O, Arumí-Uría M, Pijuan L, Menéndez S, Zazo S, Dómine M, Salido M, Mojal S, García de Herreros A, Rovira A, Albanell J, Arriola E.Targeting epithelial-to-mesenchymal transition with Met inhibitors reverts chemoresistance in small cell lung cancer.Clin Cancer Res. 2014 Feb 15;20(4):938-50. doi: 10.1158/1078-0432.CCR-13-1330. Epub 2013 Nov 27..PubMed PMID:24284055


Dalmases Alba González Irene Menendez Silvia Arpí Oriol Corominas Josep Maria Servitja Sonia Tusquets Ignasi Chamizo Cristina Rincón Raúl Espinosa Lluis Bigas Anna Eroles Pilar Furriol Jessica Lluch Anna Rovira Ana Albanell Joan Rojo Federico .Deficiency in p53 is required for doxorubicin induced transcriptional activation of NF-кB target genes in human breast cancer.Oncotarget. 2014 Jan 15;5(1):196-210..PubMed PMID:24344116


Rojo Federico Domingo Laia Sala Maria Zazo Sandra Chamizo Cristina Menendez Silvia Arpi Oriol Corominas Josep Maria Bragado Rafael Servitja Sonia Tusquets Ignasi Nonell Lara Macià Francesc Martínez Juan Rovira Ana Albanell Joan Castells Xavier .Gene expression profiling in true interval breast cancer reveals overactivation of the mTOR signaling pathway.Cancer Epidemiol Biomarkers Prev. 2014 Feb;23(2):288-99. doi: 10.1158/1055-9965.EPI-13-0761. Epub 2013 Dec 17..PubMed PMID:24347552


Llamas-Velasco M, Pérez-Gónzalez YC, Requena L, Kutzner H.Histopathologic clues for the diagnosis of Wiesner nevus.J Am Acad Dermatol. 2014 Mar;70(3):549-54. doi: 10.1016/j.jaad.2013.10.032. Epub 2013 Dec 24..PubMed PMID:24373783


Alba E, Albanell J, de la Haba J, Barnadas A, Calvo L, Sánchez-Rovira P, Ramos M, Rojo F, Burgués O, Carrasco E, Caballero R, Porras I, Tibau A, Cámara MC, Lluch A.Trastuzumab or lapatinib with standard chemotherapy for HER2-positive breast cancer: results from the GEICAM/2006-14 trial.Br J Cancer. 2014 Mar 4;110(5):1139-47. doi: 10.1038/bjc.2013.831. Epub 2014 Jan 23..PubMed PMID:24457911


Llamas-Velasco Mar Fraga Javier Kutzner Heinz Steegmann Juan Luis García-Diez Amaro Requena Luis .Hypopigmented macules secondary to imatinib for the treatment of chronic myeloid leukemia: a histopathologic and immunohistochemical study.J Cutan Pathol. 2014 May;41(5):417-26. doi: 10.1111/cup.12298. Epub 2014 Feb 26..PubMed PMID:24467724


Plaza JA, Kazakov DV, Casas G, Requena L, Sanmartin O, Kacerovska D, Michal M, Schmoranzova A, Suster S, Sangueza M.Fibrolipomatous hamartoma of the nerve: a clinicopathologic report of 13 cases.J Am Acad Dermatol. 2014 Apr;70(4):736-42. doi: 10.1016/j.jaad.2013.10.002. Epub 2014 Jan 27..PubMed PMID:24480457


Riester Markus Werner Lillian Bellmunt Joaquim Selvarajah Shamini Guancial Elizabeth A Weir Barbara A Stack Edward C Park Rachel S O'Brien Robert Schutz Fabio A B Choueiri Toni K Signoretti Sabina Lloreta Josep Marchionni Luigi Gallardo Enrique Rojo Federico Garcia Denise I Chekaluk Yvonne Kwiatkowski David J Bochner Bernard H Hahn William C, Ligon Azra H, Barletta Justine A, Loda Massimo, Berman David M, Kantoff Philip W, Michor Franziska, Rosenberg Jonathan E, .Integrative analysis of 1q23.3 copy-number gain in metastatic urothelial carcinoma.Clin Cancer Res. 2014 Apr 1;20(7):1873-83. doi: 10.1158/1078-0432.CCR-13-0759. Epub 2014 Jan 31..PubMed PMID:24486590


Vaqué José P Gómez-López Gonzalo Monsálvez Verónica Varela Ignacio Martínez Nerea Pérez Cristina Domínguez Orlando Graña Osvaldo Rodríguez-Peralto José L Rodríguez-Pinilla Socorro M González-Vela Carmen Rubio-Camarillo Miriam Martín-Sánchez Esperanza Pisano David G Papadavid Evangelia Papadaki Theodora Requena Luis García-Marco José A Méndez Miriam Provencio Mariano Hospital Mercedes, Suárez-Massa Dolores, Postigo Concepción, San Segundo David, López-Hoyos Marcos, Ortiz-Romero Pablo L, Piris Miguel A, Sánchez-Beato Margarita, .PLCG1 mutations in cutaneous T-cell lymphomas.Blood. 2014 Mar 27;123(13):2034-43. doi: 10.1182/blood-2013-05-504308. Epub 2014 Feb 4..PubMed PMID:24497536


Vañó-Galván S, Molina-Ruiz AM, Serrano-Falcón C, Arias-Santiago S, Rodrigues-Barata AR, Garnacho-Saucedo G, Martorell-Calatayud A, Fernández-Crehuet P, Grimalt R, Aranegui B, Grillo E, Diaz-Ley B, Salido R, Pérez-Gala S, Serrano S, Moreno JC, Jaén P, Camacho FM.Frontal fibrosing alopecia: a multicenter review of 355 patients.J Am Acad Dermatol. 2014 Apr;70(4):670-8. doi: 10.1016/j.jaad.2013.12.003. Epub 2014 Feb 5..PubMed PMID:24508293


Machan S, El Shabrawi-Caelen L, Nikolay E, Kerl H, Requena L, Cerroni L.Follicular malignant melanoma: primary follicular or folliculotropic?Am J Dermatopathol. 2015 Jan;37(1):15-9. doi: 10.1097/DAD.0000000000000087..PubMed PMID:24614208


Manso R, Rodríguez-Pinilla SM, Lombardia L, Ruiz de Garibay G, Del Mar López M, Requena L, Sánchez L, Sánchez-Beato M, Piris MÁ.An A91V SNP in the perforin gene is frequently found in NK/T-cell lymphomas.PLoS One. 2014;9(3):e91521. doi: 10.1371/journal.pone.0091521..PubMed PMID:24632576


Kacerovska D, Requena L, Carlson JA, Santonja C, Michal M, Bouda J, Konstantinova AM, Kaspirkova J, Fikrle T, Rotter L, Kazakov DV.Pigmented squamous intraepithelial neoplasia of the anogenital area: a histopathological and immunohistochemical study of 64 specimens from 45 patients exploring the mechanisms of pigmentation.Am J Dermatopathol. 2014 Jun;36(6):471-7. doi: 10.1097/DAD.0000000000000007..PubMed PMID:24698935


Molina-Ruiz AM, García-Gavín P, García-Gavín J, Boada-García A, Carrascosa-Carrillo JM.Actas Dermo-sifiliográficas on Facebook.Actas Dermosifiliogr. 2014 Sep;105(7):635-8. doi: 10.1016/j.ad.2014.02.007. Epub 2014 Apr 4. English, Spanish. .PubMed PMID:24704189


Plaza JA, Requena L, Kazakov DV, Vega E, Kacerovska D, Reyes G, Michal M, Suster S, Sangueza M.Verrucous localized lymphedema of genital areas: clinicopathologic report of 18 cases of this rare entity.J Am Acad Dermatol. 2014 Aug;71(2):320-6. doi: 10.1016/j.jaad.2014.01.907. Epub 2014 Apr 14..PubMed PMID:24726400


Requena C Requena L Alegre V Serra C Llombart B Nagore E Guillén C Sanmartín O .Adverse reaction to silicone simulating orofacial granulomatosis.J Eur Acad Dermatol Venereol. 2015 May;29(5):998-1001. doi: 10.1111/jdv.12522. Epub 2014 Apr 21..PubMed PMID:24750369


Manso R, Sánchez-Beato M, Monsalvo S, Gómez S, Cereceda L, Llamas P, Rojo F, Mollejo M, Menárguez J, Alves J, García-Cosio M, Piris MA, Rodríguez-Pinilla SM.The RHOA G17V gene mutation occurs frequently in peripheral T-cell lymphoma and is associated with a characteristic molecular signature.Blood. 2014 May 1;123(18):2893-4. doi: 10.1182/blood-2014-02-555946. .PubMed PMID:24786457


Torrelo A Vicente A Navarro L Planaguma M Bueno E González-Sarmiento R Hernández-Martín A Noguera-Morel L Requena L Colmenero I Parareda A González-Enseñat M A Happle R .Early-onset acral basal cell carcinomas in Gorlin syndrome.Br J Dermatol. 2014 Nov;171(5):1227-9. doi: 10.1111/bjd.13118. Epub 2014 Oct 1..PubMed PMID:24837096


Torrelo Antonio Azorín Daniel Noguera Lucero Hernández-Martín Angela Happle Rudolf Requena Luis .Segmental prurigo pigmentosa.Pediatr Dermatol. 2014 Jul-Aug;31(4):523-5. doi: 10.1111/pde.12349. Epub 2014 May 20..PubMed PMID:24846714


Cristóbal I, Aguilera O, García-Foncillas J, Zazo S, Madoz-Gúrpide J, Rojo F.Clinical significance of miR-126 in colorectal cancer.Genes Chromosomes Cancer. 2014 Oct;53(10):881. doi: 10.1002/gcc.22192. Epub 2014 Jun 4. .PubMed PMID:24898922


Pielasinski U, Santonja C, Rodríguez-Pinilla SM, Requena L.Extracavitary primary effusion lymphoma presenting as a cutaneous tumor: a case report and literature review.J Cutan Pathol. 2014 Sep;41(9):745-53. doi: 10.1111/cup.12368. Epub 2014 Jul 28..PubMed PMID:24917369


Alba-Castellón L, Batlle R, Francí C, Fernández-Aceñero MJ, Mazzolini R, Peña R, Loubat J, Alameda F, Rodríguez R, Curto J, Albanell J, Muñoz A, Bonilla F, Ignacio Casal J, Rojo F, García de Herreros A.Snail1 expression is required for sarcomagenesis.Neoplasia. 2014 May;16(5):413-21. doi: 10.1016/j.neo.2014.05.002. Epub 2014 Jun 16..PubMed PMID:24947186


García-Camba P, Varela M, Requena L.Capacity of dermatologists to diagnose oral and perioral lesions compared with orthodontists, primary care physicians, and pediatricians.Am J Dermatopathol. 2014 Dec;36(12):952-8. doi: 10.1097/DAD.0000000000000107..PubMed PMID:25014104


Rodriguez HO, Guerrero NA, Fortes A, Santi-Rocca J, Gironès N, Fresno M.Trypanosoma cruzi strains cause different myocarditis patterns in infected mice.Acta Trop. 2014 Nov;139:57-66. doi: 10.1016/j.actatropica.2014.07.005. Epub 2014 Jul 11..PubMed PMID:25017312


Fernández-Barral A, Orgaz JL, Baquero P, Ali Z, Moreno A, Tiana M, Gómez V, Riveiro-Falkenbach E, Cañadas C, Zazo S, Bertolotto C, Davidson I, Rodríguez-Peralto JL, Palmero I, Rojo F, Jensen LD, Del Peso L, Jiménez B.Regulatory and functional connection of microphthalmia-associated transcription factor and anti-metastatic pigment epithelium derived factor in melanoma.Neoplasia. 2014 Jun;16(6):529-42. doi: 10.1016/j.neo.2014.06.001. Epub 2014 Jul 13..PubMed PMID:25030625


Machan S, Molina-Ruiz AM, Fernández-Aceñero MJ, Encabo B, LeBoit P, Bastian BC, Requena L.Metastatic Melanoma in Association With a Giant Congenital Melanocytic Nevus in an Adult: Controversial CGH Findings.Am J Dermatopathol. 2014 Jul 24. [Epub ahead of print].PubMed PMID:25062263


Carranza C, Molina-Ruiz AM, Pérez de la Fuente T, Kutzner H, Requena L, Santonja C.Subungual Acral Fibromyxoma Involving the Bone: A Mimicker of Malignancy.Am J Dermatopathol. 2014 Jul 24. [Epub ahead of print].PubMed PMID:25062265


Woltsche NM, Cota C, Fink-Puches R, Requena L, Cerroni L.Bullous melanoma: a rare variant of melanoma causing practical problems in determination of tumor thickness.Am J Dermatopathol. 2015 Feb;37(2):133-7. doi: 10.1097/DAD.0000000000000179..PubMed PMID:25079203


Rütten A Mentzel T Requena L .[Endocrine mucin-producing sweat gland carcinoma. three case reports with a brief review of the literature].Pathologe. 2014 Sep;35(5):462-6. doi: 10.1007/s00292-014-1936-9. German. .PubMed PMID:25085634


Gantner Susanne Rütten Arno Requena Luis Gassenmaier Gerhard Landthaler Michael Hafner Christian .CHILD syndrome with mild skin lesions: histopathologic clues for the diagnosis.J Cutan Pathol. 2014 Oct;41(10):787-90. doi: 10.1111/cup.12377. Epub 2014 Oct 18..PubMed PMID:25093865


García-Parra J, Dalmases A, Morancho B, Arpí O, Menendez S, Sabbaghi M, Zazo S, Chamizo C, Madoz J, Eroles P, Servitja S, Tusquets I, Yelamos J, Lluch A, Arribas J, Rojo F, Rovira A, Albanell J.Poly (ADP-ribose) polymerase inhibition enhances trastuzumab antitumour activity in HER2 overexpressing breast cancer.Eur J Cancer. 2014 Oct;50(15):2725-34. doi: 10.1016/j.ejca.2014.07.004. Epub 2014 Aug 12..PubMed PMID:25128455


Molina-Ruiz Ana M Santonja Carlos Rütten Arno Cerroni Lorenzo Kutzner Heinz Requena Luis .Immunohistochemistry in the diagnosis of cutaneous viral infections- part II: cutaneous viral infections by parvoviruses, poxviruses, paramyxoviridae, picornaviridae, retroviruses and filoviruses.Am J Dermatopathol. 2015 Feb;37(2):93-106. doi: 10.1097/DAD.0000000000000200..PubMed PMID:25171430


Molina-Ruiz Ana M Santonja Carlos Rütten Arno Cerroni Lorenzo Kutzner Heinz Requena Luis .Immunohistochemistry in the diagnosis of cutaneous viral infections--part I. Cutaneous viral infections by herpesviruses and papillomaviruses.Am J Dermatopathol. 2015 Jan;37(1):1-14; quiz 12-4. doi: 10.1097/DAD.0000000000000203..PubMed PMID:25171431


Kofler Heinz Lipsker Dan Maurer Heiner Burgdorf Walter Requena Luis Torrelo Antonio Zelger Bernhard Kutzner Heinz Müller Hansgeorg .Self-healing juvenile cutaneous mucinosis: challenging diagnosis and management.J Dtsch Dermatol Ges. 2014 Sep;12(9):815-7. doi: 10.1111/ddg.12379. .PubMed PMID:25176461


Boixeda P Feltes F Santiago J L Paoli J .Future Prospects in Dermatologic Applications of Lasers, Nanotechnology, and Other New Technologies.Actas Dermosifiliogr. 2015 Apr;106(3):168-179. doi: 10.1016/j.ad.2014.07.002. Epub 2014 Sep 3. English, Spanish. .PubMed PMID:25193425


Requena L Torrelo A .Paediatric vascular tumours other than infantile haemangioma.Br J Dermatol. 2014 Sep;171(3):464-5. doi: 10.1111/bjd.12917. .PubMed PMID:25234065


Trindade Felicidade Torrelo Antonio Kutzner Heinz Requena Luis Tellechea Óscar Colmenero Isabel .An immunohistochemical study of angiokeratomas of children.Am J Dermatopathol. 2014 Oct;36(10):796-9. doi: 10.1097/DAD.0000000000000224..PubMed PMID:25243395


Llamas-Velasco Mar Solano-López Morel Guillermo Enrique Gruber-Wackernagel Alexandra Concha-Garzón Maria Jose Requena Luis Cerroni Lorenzo .Comedonal graft-vs-host disease: a distinct clinical expression of a lichenoid follicular GVHD.J Cutan Pathol. 2014 Nov;41(11):853-8. doi: 10.1111/cup.12391. Epub 2014 Oct 28..PubMed PMID:25264218


Llamas-Velasco M Requena L Kutzner H Schärer L Rütten A Hantschke M Paredes B E Mentzel T .Fumarate hydratase immunohistochemical staining may help to identify patients with multiple cutaneous and uterine leiomyomatosis (MCUL) and hereditary leiomyomatosis and renal cell cancer (HLRCC) syndrome.J Cutan Pathol. 2014 Nov;41(11):859-65. doi: 10.1111/cup.12396. Epub 2014 Nov 4..PubMed PMID:25292446


Llamas-Velasco Mar Requena Luis Podda Maurizio Weidenthaler-Barth Beate Rütten Arno .Apocrine intraductal carcinoma in situ in nevus sebaceus: two case reports.J Cutan Pathol. 2014 Dec;41(12):944-9. doi: 10.1111/cup.12394. Epub 2014 Nov 11..PubMed PMID:25302933


Manso Rebeca Rodríguez-Pinilla Socorro M González-Rincón Julia Gómez Sagrario Monsalvo Silvia Llamas Pilar Rojo Federico Pérez-Callejo David Cereceda Laura Limeres Miguel A Maeso Carmen Ferrando Lucía Pérez-Seoane Carlos Rodríguez Guillermo Arrinda Jose M García-Bragado Federico Franco Renato Rodríguez-Peralto Jose' L González-Carreró Joaquín Martín-Dávila Francisco Piris Miguel A, Sánchez-Beato Margarita, .Recurrent presence of the PLCG1 S345F mutation in nodal peripheral T-cell lymphomas.Haematologica. 2015 Jan;100(1):e25-7. doi: 10.3324/haematol.2014.113696. Epub 2014 Oct 10. .PubMed PMID:25304611


Bartolome Ruben Pelaez-Garcia Alberto Gomez Inmaculada Torrres Sofia Fernandez-Acenero Maria Jesus Escudero-Paniagua Beatriz Imbaud J Ignacio Casal J Ignacio .An RGD motif present in cadherin 17 induces integrin activation and tumor growth.J Biol Chem. 2014 Dec 12;289(50):34801-14. doi: 10.1074/jbc.M114.600502. Epub 2014 Oct 21..PubMed PMID:25336636


Martín-Sánchez Esperanza Odqvist Lina Rodríguez-Pinilla Socorro M Sánchez-Beato Margarita Roncador Giovanna Domínguez-González Beatriz Blanco-Aparicio Carmen García Collazo Ana M Cantalapiedra Esther González Fernández Joaquín Pastor Olmo Soraya Curiel Del Pisonero Helena Madureira Rebeca Almaraz Carmen Mollejo Manuela Alves F Javier Menárguez Javier González-Palacios Fernando Rodríguez-Peralto José Luis Ortiz-Romero Pablo L Real Francisco X, García Juan F, Bischoff James R, Piris Miguel A, .PIM kinases as potential therapeutic targets in a subset of peripheral T cell lymphoma cases.PLoS One. 2014;9(11):e112148. doi: 10.1371/journal.pone.0112148..PubMed PMID:25386922


Bernárdez Claudia Vallés Lara Santonja Carlos Requena Luis .Cutaneous lupus erythematosus with histopathologic changes restricted to the acrosyringia.Am J Dermatopathol. 2014 Dec;36(12):994-6. doi: 10.1097/DAD.0000000000000134..PubMed PMID:25415142

Projects and Contracts (2013)

1. "Contrato de servicios entre la empresa ROCHE DIAGNOSTICS S.L. y la FUNDACIÓN JIMÉNEZ DÍAZ-UTE" Investigador Principal Dr. F. Manzarbeitia Arambarri.

Financiación privada 5129/003.

2. "Identificación de mecanismos de resistencia a nuevos anticuerpos ANTI-HER2en cáncer de mama" Investigador Principal Dr. F. G. Rojo Todo.

Proyecto competitivo PI12/01552.

3. "RETICS de Biobancos"Investigador Principal Dr. F. G. Rojo Todo.

Proyecto competitivo RD09/0076/00101.

4. "Transcriptoma, proteoma e interactoma en el tejido epitelial y estromal del colon humano y sus alteraciones patológicas" Investigador Principal Dr. F. G. Rojo Todo.

Proyecto competitivo S2010/BMD-2344 COLOMICS2.

5. "Identificación proteómica de MKP-1 en el cáncer de mama de fenotipo basal (triple negativo): empleo como marcador predictivo de quimiorresistencia y potencial diana terapéutica" Investigador Principal Dr. F. G. Rojo Todo.

Financiación privada 9757/002.

6. "Contrato marco de prestación de servicios GEICAM y IIS-FJD" Investigador Principal Dr. F. G. Rojo Todo. Financiación privada 9757/003.

Clinical trials and Observational studies (2013)

1. Observational studies "Estudio epidemiológico observacional para evaluar la retención en el tratamiento de los pacientes con psoriasis de moderada a grave en la práctica clínica". Ref. 4382/003.

Investigadora Principal: Mª del Carmen Fariña Sabaris.

2. Observational studies "Impacto pronóstico de las mutaciones de baja prevalencia de KRAS y BRAF en cáncer colorrectal metastásico". Ref. EO 41/2011

Investigador Principal Dr. Federico Gustavo Rojo Todo.