Data update as of 01/10/2026


6.1.1. GRUPO DE ANATOMÍA PATOLÓGICA-220707-FOTO MONTAJE6.1.1. GRUPO DE ANATOMÍA PATOLÓGICA-220707-FOTO MONTAJE2025 DATA

Leaders:

Research:

  • Basic
  • Translational
  • Clinical

Location

Department of Pathology

Main Building, 8th and 9th Floors

Fundación Jiménez Díaz University Hospital

Avda. Reyes Católicos, 2. 28040 Madrid (Spain)


Pathology Laboratory

Research Building, 4th Floor

Fundación Jiménez Díaz University Hospital

Avda. Reyes Católicos, 2. 28040 Madrid (Spain)


Key words

Breast cancer, T-cell lymphomas, molecular pathology, tumour microenvironment, immunotherapy, prognostic and predictive factors in cancer, therapeutic resistance.


Gender perspective

Anatomía patológica-01Anatomía patológica-01

Summary of activities

Advances in breast cancer research, together with increased patient awareness, have significantly improved the diagnosis, treatment and survival rates associated with this disease. However, current therapies remain ineffective for a substantial proportion of patients, highlighting the need for further improvements in both survival and quality of life. Our Molecular Pathology group is dedicated to cancer research, particularly breast cancer, and has made important contributions to understanding the mechanisms underlying resistance to specific anticancer therapies.

The group focuses on two main objectives: identifying robust biomarkers capable of predicting resistance to current treatments and developing new therapeutic strategies to overcome resistance to first-line therapies. In recent years, the group has investigated mechanisms of treatment resistance and identified new therapeutic approaches, with particular emphasis on the role of the tumour microenvironment and specific cellular populations in determining treatment efficacy. In addition, the group collaborates extensively with other research teams to uncover new biological mechanisms and potential therapeutic targets.

The group is also actively involved in clinical trials evaluating new drugs and therapeutic approaches in patients, and its research has been instrumental in the design of innovative clinical studies. Beyond its research activities, the group plays an important role in the management of biological samples and the coordination of research initiatives, always with the aim of improving the care and treatment of patients with breast cancer.

In parallel, the group is actively engaged in the study of lymphoma biology, with a particular focus on T-cell lymphomas. Its research projects are aimed at identifying prognostic biomarkers and novel therapeutic targets that may contribute to improved patient outcomes.


Contributions to society

In 2025, our group published several scientific articles on the molecular mechanisms underlying tumour resistance and presented its findings at national and international conferences, as well as at educational forums and patient association events. Several doctoral theses are currently being conducted within the laboratory, which also hosts students, medical residents and research fellows.

The group actively participates in patient groups, patient associations and cooperative breast cancer research networks. Clinically relevant findings are disseminated through these channels whenever appropriate. In addition, the group is a member of CIBERONC (Center for Biomedical Network Research on Cancer), which further enhances the visibility and dissemination of its research outcomes.

The investigators leading these projects are strongly committed to communicating research findings to society, with the aim of increasing public awareness of this disease and of advances that may contribute to improving patient outcomes. The Group collaborates closely with patient organisations such as AECC, GEPAC, FECMA and AECMM, and regularly participates in public forums and meetings organised by these associations.

The group also collaborates with the INVI Male Breast Cancer Association, incorporating a gender perspective into its research on a disease that, although predominantly affecting women, can also occur in men.


Collaborations

During 2025, the group established and maintained collaborations with several national and international research teams through high-impact research projects funded by the Carlos III Health Institute (ISCIII), the Community of Madrid and European programmes. Within the Fundación Jiménez Díaz Health Research Institute (IIS-FJD), the group worked closely with numerous research groups, both within the Cancer Area and across other research programmes. In addition, the group is a member of CIBERONC (ISCIII's Cancer Research Network Biomedical Research Centre), GEICAM and GEMCAD.

These collaborations have enabled significant scientific advances. The group has identified a new mechanism with potential applications in combating breast cancer and has developed experimental models that improve our understanding of how certain tumours acquire resistance to standard therapies. Furthermore, the group has made important contributions to the coordination of innovative clinical trials, with the goal of improving treatment outcomes and the quality of life of patients.



PhD Theses



Anatomía patológica-02Anatomía patológica-02

List of publications

Total neoadjuvant therapy in rectal cancer: The FOREST protocol, a patient-centered approach that clusters two cohorts with different outcomes.

Guadalajara H, Domínguez-Tristancho JL, Mateo RF, Leon-Arellano M, Sanz-Baro R, Geraldi E, Hormigo-Sanchez AI, Megías VMC, Cobos MP, Miras PM, Zulueta BL, Garcia-Arranz M, Foncillas JG, Caramés C, García-Olmo D.

Int J Cancer. 2026 Feb 01.158(3):697-706.

PMID: 40947902

FI: 4,7

http://dx.doi.org/10.1002/ijc.70126This link opens in a popup window


Overview of the multidisciplinary team activity in patients with hepatocellular carcinoma and their survival outcomes.

Guarini V, Garzòn C, Casado D, Casanova M, Villarejo P, Azinovic I, Crespo E, Fernandez I, Lopez M, de Bourio MM, Moran M, Jimenez M, Medrano G, Castellano V, Lamarca A.

ESMO Gastrointest Oncol. 2025 Dec.10 (2025): 100263.

PMID: 10.1016/j.esmogo.2025.100263

FI: 0

http://dx.doi.org/10.1016/j.esmogo.2025.100263This link opens in a popup window


CCL18: a potential immunosuppressive biomarker for prognosis in ABC diffuse large B-cell lymphoma.

Rodríguez M, Rojas-Vega F, Díaz-Alejo JF, Mahillo-Fernández I, Serrano C, López A, Morales-Ruiz T, Roldan-Arjona T, Sánchez-García J, Río-Machín A, Morillo D, Pérez MA, Córdoba R, Llamas-Sillero P, Rodríguez-Pinilla SM, Serrano-López J.

Front Immunol. 2025.16:1693730.

PMID: 41472741

FI: 5,9

http://dx.doi.org/10.3389/fimmu.2025.1693730This link opens in a popup window


Discordant Patch Test Reactions to 2-Bromo-2-Nitro-Propane-1,3-Diol (Bronopol): A Multicenter Study From REIDAC.

Sánchez TS, Giménez-Arnau AM, Ninet VZ, Guijarro SC, Miquel FJM, Salvador JFS, Pérez RG, González IR, Mercader-García P, Baldrich ES, Carrillo JMC, Romero FT, de Frutos FJO, Serna MR, Ortega MEG, Suárez CP, Navarro-Triviño F, Chicharro P, Nieto MAP, de la Fuente EG, Sánchez-Gilo A, Andreu-Barasoain M, Pereyra Rodríguez JJ, Ninot GMI, Guillén PS, Elosua-González M, Grau-Pérez M, Descalzo MÁ, Borrego L.

Contact Dermatitis. 2025 Dec 28.

PMID: 41456936

FI: 4,6

http://dx.doi.org/10.1111/cod.70082This link opens in a popup window


A novel GATA1 variant linking germline and somatic myelodysplastic syndrome in two patients.

Revilla N, Atance M, Grasa JM, García-Ortego A, Soto C, Rodríguez-Pinilla SM, Arquero T, Perlado S, Ledesma S, Esquinas-Tarifa E, Serrano-López J, López-Lorenzo JL, Velasco-Rodríguez D, Alonso-Dominguez JM, Mata R, Llamas-Sillero P, Salgado RN, Rio-Machin A.

Haematologica. 2025 Dec 24.

PMID: 41437813

FI: 7,9

http://dx.doi.org/10.3324/haematol.2025.289133This link opens in a popup window


Histopathologic Diagnostic Agreement Study in Bone and Soft Tissue Tumors: The SELNET Sarcoma Network Experience.

Righi A, Gambarotti M, Ramos R, Guzman R, Hernandez-Leon CN, Romagosa C, Merino J, Casavilca S, Castro V, Haro JC, Cabañas ML, Gonzalez ML, Costa F, Campos F, Limon R, Claros Mercado E, Gonzalez L, Chacon M, Pacheco M, Aguil G, Donato Acuña M, Jimenez N, Badilla R, Chaves Quesada G, German G, Fili T, Buscaglia F, Devaud N, Matamala L, Caro H, Blay JY, Collini P, Provenzano S, Hindi N, Gutierrez A, Lopes David BB, Moura DS, Sbaraglia M, Martin-Broto J, Dei Tos AP.

JCO Glob Oncol. 2025 Dec.11:e2500394.

PMID: 41397194

FI: 3,3

http://dx.doi.org/10.1200/GO-25-00394This link opens in a popup window


Neoadjuvant Abemaciclib plus Letrozole vs. Chemotherapy in patients with HR+/HER2- Highly Proliferative Breast Cancer.

Martín M, Guerrero-Zotano AL, Pérez-López ME, Ruiz-Borrego M, Martinez Jañez N, Chacón JI, Gil-Gil M, Andrés R, Bermejo B, Sánchez-Rovira P, Del Barco S, Ponce JJ, Fernandez I, Martínez de Dueñas E, Hinojo-Gonzále C, González M, García-Garre E, Hernando B, de la Haba-Rodriguez J, Álvarez IM, González-Santiago S, Garcia-Saenz JA, Santaballa A, Casas M, Bezares S, Caballero R, Rojo F, Alba E.

Clin Cancer Res. 2025 Dec 12.

PMID: 41385615

FI: 10,2

http://dx.doi.org/10.1158/1078-0432.CCR-25-2435This link opens in a popup window


Anogenital Contact Dermatitis in Spain: A REIDAC Study of Patients Undergoing Patch Testing in 2019-2024.

Grau-Pérez M, Mercader-García P, Giménez-Arnau AM, Sanz-Sánchez T, Ninet VZ, Guijarro SC, Miquel FJM, Salvador JFS, González-Pérez R, González IR, Baldrich ES, Carrascosa JM, de Frutos FJO, Serna MR, Ortega MEG, Suárez CP, Triviño FJN, Chicharro P, Andreu M, Gilo AS, Pereyra Rodríguez JJ, Nieto MAP, Melé-Ninot G, Guillén PS, de la Fuente EG, Elosua-González M, Munera-Campos M, Romero FT, Descalzo MÁ, Borrego L.

Contact Dermatitis. 2025 Dec 09.

PMID: 41365615

FI: 4,6

http://dx.doi.org/10.1111/cod.70048This link opens in a popup window


Subungual Reactive Eccrine Syringofibroadenoma: A Case Report.

Areán C, Revilla D, Miñano R, Eraña I, Jo M, Requena L.

Am J Dermatopathol. 2025 Dec 05.

PMID: 41349045

FI: 1

http://dx.doi.org/10.1097/DAD.0000000000003188This link opens in a popup window


CLDN18.2 expression in gastroesophageal adenocarcinoma: prevalence, heterogeneity, and prognostic implications in Spanish patients.

Martinez-Ciarpaglini C, Ortega M, Pérez-Buira S, Bolea A, Casado Guerra B, Herencia Bellido C, Tornero Piñero P, Naranjo-Hans D, Palomar B, Quiceno H, Sardón Fernández A, Torner Calvo A, Rojo F, Iglesias Coma M.

Virchows Arch. 2025 Dec.487(6):1337-1346.

PMID: 41206380

FI: 3,1

http://dx.doi.org/10.1007/s00428-025-04247-7This link opens in a popup window


Lymphangiectasia and genital lymphedema secondary to metastatic Crohn's.

Román Mendoza NM, Caro Gutiérrez MD, Mateos Rico JJ, Alegre Bailo A, Estrada Muñoz L, Vicente Martín FJ.

An Bras Dermatol. 2025.100(4):501150.

PMID: 40614548

FI: 3,6

http://dx.doi.org/10.1016/j.abd.2025.501150This link opens in a popup window


Ultrasound-guided postmortem biopsies in the ICU: diagnostic yield and future applications beyond the pandemic.

Vidal González Á, Páez Vargas JJ, Robaglia D, Vicente Montaña AM, Fortes Alen JR, Prieto Pérez L.

Med Intensiva (Engl Ed). 2025 Nov 26:502362.

PMID: 41309369

FI: 3,1

http://dx.doi.org/10.1016/j.medine.2025.502362This link opens in a popup window


A 62-Year-Old Woman with Diarrhea after Hematopoietic Stem-Cell Transplantation.

Suárez EU, Torres-Saavedra F, López-Lorenzo JL, Pérez-Sáenz MÁ, Pardo-Gambarte L, Solán-Blanco L, Llamas P, Carias-Calix R, Cornago-Navascues J.

NEJM Evid. 2025 Nov.4(11):EVIDmr2500142.

PMID: 41147819

FI: 0

http://dx.doi.org/10.1056/EVIDmr2500142This link opens in a popup window


Erythema Papulatum Centrifugum: A Clinically Distinct Dermatosis. CLINI-AEDV Case Series.

Allegue F, Zulaica A, Pastor-Nieto MA, Ballester-Nortes I, Fernández-Tapia V, Parera-Amer ME, García-Doval I.

Actas Dermosifiliogr. 2025 Nov-Dec;116(10):T1126-T1130.

PMID: 41067618

FI: 2,8

http://dx.doi.org/10.1016/j.ad.2025.10.006This link opens in a popup window


Cutaneous AL-Type Amyloidomas as a Variant of Primary Cutaneous Marginal Zone Lymphoma: A Series of 30 Patients.

García-González S, García-García M, Miguel Miguel C, Córdoba Iturriagagoitia A, Yanguas Bayona JI, Nájera Botello L, Cabeza Martínez R, Santos-Briz Terrón Á, Torre Castro J, Sánchez Martínez E, Rodríguez Pinilla SM, Hillen U, Requena Caballero C, Cerroni L, Martínez Cisneros SP, Lezcano Biosca V, Carracedo Vega E, Diaz de la Pinta FJ, Prieto-Torres L.

Am J Dermatopathol. 2025 Nov 01.47(11):846-856.

PMID: 40905400

FI: 1

http://dx.doi.org/10.1097/DAD.0000000000003124This link opens in a popup window


Next-generation sequencing of TCR clonality discriminates tumor-stage mycosis fungoides from coexisting CD30+ lymphoproliferative disorders.

Torre-Castro J, Manso R, Morales Gallego M, Rodríguez Pinilla SM.

Leuk Lymphoma. Epub 2025 Oct 16. 2026 Jan.67(1):213-217.

PMID: 41103124

FI: 2,2

http://dx.doi.org/10.1080/10428194.2025.2568743This link opens in a popup window


The Rising Impact of HPV Infection in the Antiretroviral Therapy (ART) Era.

Asensi-Díaz E, Carrillo I, Al-Hayani A, Mejías-Ledesma M, Guadalajara H, Azinovic I, Trsitancho JLD, Vidal LS, Castellano V, García-Olmo D, Górgolas M, Cabello-Úbeda A.

Curr HIV Res. 2025 Oct 14.

PMID: 41102961

FI: 1

http://dx.doi.org/10.2174/011570162X381694250925045507This link opens in a popup window


Rapidly Growing Thyroid Masses in Adults: Urgent Diagnostic Challenges and Effective Management-Single-Center Experience and Literature Review.

Miguélez González M, Fernández Sánchez Á, Álvarez Álvarez MB, Quiceno Arias HD, Osorio Silla I.

World J Surg. 2025 Oct.49(10):2777-2781.

PMID: 40879557

FI: 2,5

http://dx.doi.org/10.1002/wjs.70063This link opens in a popup window


Differences in histopathologic features and diagnostic performance of 99mTc-methoxy-isobutyl-isonitrol single photon emission tomography-CT and 18F-fluorocholine positron emission tomography-CT in primary hyperparathyroidism.

Osorio-Silla I, González DM, Quiceno Arias HD, Peinado PP, Cárdenas Salas JJ, González MM, Pestana Soares CA, Martínez Ruiz LF, Landaeta Kancev LC, Dhier LM, Escanciano M, Sánchez de Molina ML, Ruíz AP, Campos PV.

Surgery. 2025 Oct.186:109595.

PMID: 40782725

FI: 2,7

http://dx.doi.org/10.1016/j.surg.2025.109595This link opens in a popup window


Cutaneous Graft-Versus-Host Disease Lichen Spinulosus-like: a New Form of Presentation of an Old Entity.

Vidal González A, Taboada Paz L, López Alcázar S, Requena Caballero L, Feito Rodríguez M.

Acta Derm Venereol. 2025 Sep 30.105:adv44373.

PMID: 41024729

FI: 3,7

http://dx.doi.org/10.2340/actadv.v105.44373This link opens in a popup window


Aurora kinase A drives non-canonical YAP1/TAZ crosstalk to sustain primary resistance to anti-EGFR therapies in colorectal cancer.

Rio-Vilariño A, Garcia-Bautista A, Cenigaonandia-Campillo A, Mateos-Gomez PA, Garcia-Garcia L, Schlaepfer MI, Garcia-Hernandez L, Puerto-Nevado LD, Aguilera O, Baños N, Minguez P, Castellano VM, Garcia-Foncillas J, Cebrian A.

Mol Ther Oncol. 2025 Sep 18.33(3):201032.

PMID: 40917509

FI: 5,3

http://dx.doi.org/10.1016/j.omton.2025.201032This link opens in a popup window


Skin manifestations uncover underlying Follicular helper T-cell lymphoma, angioimmunoblastic-type in an immunosuppressed patient.

García ML, Manso R, Castro JT, Pascual LP, Cillán SR, Morillo D, Hernaez JCC, Climent F, Requena L, Pinilla SMR, de la Pinta FJD.

Virchows Arch. 2025 Sep 03.

PMID: 40900230

FI: 3,1

http://dx.doi.org/10.1007/s00428-025-04244-wThis link opens in a popup window


Reply to: Germline and Somatic BRCA1/2 Mutations in Breast Cancer Treatment Strategies.

Hahnen E, Hauke J, Gelmon K, Marmé F, Ernst C, Martin M, Untch M, Bonnefoi H, Knudsen E, Im SA, DeMichele A, Van't Veer L, Kim SB, Bear H, McCarthy N, Rhiem K, Turner N, Witkiewicz A, Rojo F, Filipits M, Martin LA, Fasching PA, Schem C, Becker K, García-Sáenz JA, Kelly CM, Reimer T, Toi M, Rugo HS, Denkert C, Gnant M, Makris A, Liu Y, Valota O, Felder B, Weber K, Nekljudova V, Loibl S.

JCO Precis Oncol. 2025 Sep.9:e2500588.

PMID: 40893049

FI: 5,8

http://dx.doi.org/10.1200/PO-25-00588This link opens in a popup window


Effects of presurgical HIIT in hormone receptor-positive, HER 2-negative breast cancer cases: Two case reports from the GEICAM EFiK study.

Pérez-Bilbao T, López-Tarruella S, Alonso-Dueñas M, San Juan AF, Ferreres-García K, Martín M, Peinado AB, Rojo F.

Physiol Rep. 2025 Aug.13(16):e70511.

PMID: 40859620

FI: 1,9

http://dx.doi.org/10.14814/phy2.70511This link opens in a popup window


The Changing Spectrum of Pediatric Allergic Contact Dermatitis: A Prospective Multicentric Study in Spain.

Planella-Fontanillas N, Pesqué D, Borrego L, Zaragoza Ninet V, Miquel Miquel J, Sanz-Sánchez T, Silvestre Salvador JF, Carrascosa Carrillo JM, Munera-Campos M, Córdoba Guijarro S, González Pérez R, Serra Baldrich E, Gatica Ortega ME, Mercader-García P, Ruiz Gonzales I, Linares Navarro R, Ortiz de Frutos FJ, Tous Romero F, Rodríguez Serna M, Pastor Nieto MA, Sánchez Pérez J, Sánchez Gilo A, Melé-Ninot G, Barrabés-Torrella C, Gómez de la Fuente E, Sánchez-Pedreño Guillén P, Lova Navarro M, Navarro Triviño F, Pereyra Rodríguez JJ, Pujol RM, Ángel Descalzo M, García Doval I, Giménez-Arnau AM.

Dermatitis. 2025 Aug 18.

PMID: 40824751

FI: 3,5

http://dx.doi.org/10.1177/17103568251368314This link opens in a popup window


PD-L1 expression scoring using artificial intelligence algorithms in non-small cell lung cancer harbouring ROS1 fusions: potential clinical-biological significance.

García LF, Conde E, Hernandez S, Alonso M, Curto D, Dómine M, Rojo F, Freire J, Gómez-Román J, Calles A, Cebollero M, González-Larriba JL, Saiz M, Esteban I, Gutiérrez L, Lopez-Rios F, de Castro J.

Clin Transl Oncol. 2025 Aug 11.

PMID: 40790287

FI: 2,5

http://dx.doi.org/10.1007/s12094-025-04013-wThis link opens in a popup window


TIM3+ breast cancer cells license immune evasion during micrometastasis outbreak.

Rozalén C, Sangrador I, Avalle S, Blasco-Benito S, Tzortzi P, Sanz-Flores M, Palomeque JÁ, Torren-Duran P, Dalmau M, Brunel H, Coll-Manzano A, Pérez-Núñez I, Martos T, Servitja S, Pérez-Buira S, Chacón JI, Guerrero-Zotano Á, Martínez de Dueñas E, Guillén Y, Comerma L, Bermejo B, Bigas A, Casanova-Acebes M, Alemany A, Rojo F, Albanell J, Celià-Terrassa T.

Cancer Cell. 2025 Aug 11.43(8):1549-1567.e9.

PMID: 40645187

FI: 44,5

http://dx.doi.org/10.1016/j.ccell.2025.06.015This link opens in a popup window


Chondrodermatitis Nodularis Helicis: Association with Higher Risk of Multimorbidity and Mortality in Middle-Aged Individuals and Implications for Prevention. An Observational Multicenter Retrospective Case-Control Investigation in Northern Spain.

Vázquez-López F, Requena L, Galache C, Díaz-Louzao C, González-López MA.

Dermatol Pract Concept. 2025 Jul 31.15(3).

PMID: 40790405

FI: 2,3

http://dx.doi.org/10.5826/dpc.1503a4828This link opens in a popup window


Indocyanine Green Fluorescence Navigation in Pediatric Hepatobiliary Surgery: Systematic Review.

Delgado-Miguel C, Arredondo-Montero J, Moreno-Alfonso JC, Garavis Montagut I, Rodríguez M, Ruiz Jiménez I, Carrera N, Roncero PA, Fuentes E, Díez R, Hernández-Oliveros F.

Children (Basel). 2025 Jul 18.12(7).

PMID: 40723143

FI: 2,1

http://dx.doi.org/10.3390/children12070950This link opens in a popup window


Safety of sonidegib in elderly patients with locally advanced basal cell carcinoma: A multicentre study.

Martos-Cabrera L, Bonfill-Ortí M, Deza G, Cabrera RF, Hernandez-Hernandez MN, Pérez CA, Estrada RB, Blanco CC, Jaka A, Just-Sarobé M, Conde-Taboada A, Arenal MM, Vargas-Laguna E, Masferrer E, León IA, Leal L, Medina-Montalvo S, Polo I, Turrión-Merino L, Medina-Martínez J, Cañueto J, Vílchez-Márquez F, Moreno-Suárez F, Castaño-Uhagón I, de Casas AR, Fernández FMA, Sánchez-Aguilar MD, González-Sixto B, Feal-Cortizas JC, Sainz-Gaspar L, Cerezuela-Fuentes P, Onecha-Vallejo V, Bastante LL, Buendía-Martínez C, Hernández B, Soria A, Delgado Y, Beá-Ardebol S, Rodríguez-Jiménez P.

J Eur Acad Dermatol Venereol. 2025 Jul 11.

PMID: 40643213

FI: 8

http://dx.doi.org/10.1111/jdv.20835This link opens in a popup window


Development of SOCS1 mimetics as novel approach to harmonize inflammation, oxidative stress, and fibrogenesis in metabolic dysfunction-associated steatotic liver disease.

Bernal S, Prieto I, Kavanagh M, Del Real IH, La Manna S, Lázaro I, Quiceno H, López-Sanz L, Picatoste B, Valdecantos MP, Mas-Fontao S, Sala-Vila A, Valverde ÁM, Marasco D, Egido J, Gómez-Guerrero C.

Redox Biol. 2025 Jul.84:103670.

PMID: 40373621

FI: 11,9

http://dx.doi.org/10.1016/j.redox.2025.103670This link opens in a popup window


Primary Cutaneous Anaplastic Large Cell Lymphoma With TCR-γδ Expression: A Case Series of Eleven Patients of a Rare Immunophenotypic Variant.

Erem AS, Kempf W, Mitteldorf C, Pulitzer M, Torres-Cabala CA, Pileri S, Pinilla SMR, Feldman AL, Gru AA.

J Cutan Pathol. 2025 Jul.52(7):487-496.

PMID: 40202044

FI: 1,1

http://dx.doi.org/10.1111/cup.14809This link opens in a popup window


Effects of a nationwide teledermatology program on access to care for skin cancer and premalignant lesions in public and private health care: A retrospective case-control analysis of data from eight Spanish hospitals.

Toledo-Pastrana T, Mora D, Martin-Gutierrez F, Fernández Valdés-Martín C, Corrales-Rodriguez A, Pfang B, Villegas García MA, Alcaraz-Leon I, Vicente J, Short Apellániz J, Blanco Rubio A, Herrero A, Del Olmo M, Álvaro de la Parra JA.

J Am Acad Dermatol. 2025 Jul.93(1):281-283.

PMID: 40120816

FI: 11,8

http://dx.doi.org/10.1016/j.jaad.2025.03.037This link opens in a popup window


FOXC1 expression predicts capecitabine efficacy in triple-negative breast cancer patients from the GEICAM_CIBOMA trial.

Rojo F, Taylor CR, Barrios C, Torrecillas L, Ruiz-Borrego M, Perez-Buira S, Bines J, Guerrero-Zotano A, Garcia-Saenz JA, Torres R, de la Haba-Rodriguez J, Ayala F, Gomez H, Llombart A, Rodriguez de la Borbolla M, Baena-Cañada JM, Barnadas A, Calvo L, Herranz J, Rincon R, Caballero R, Bermejo B, Ray PS, Martín M.

Clin Cancer Res. 2025 Jun 26.

PMID: 40569606

FI: 10,2

http://dx.doi.org/10.1158/1078-0432.CCR-25-0338This link opens in a popup window


Molecular Insights into the Diagnosis of Anaplastic Large Cell Lymphoma: Beyond Morphology and Immunophenotype.

Frutos Díaz-Alejo J, Prieto-Potín I, Manso R, Rodríguez M, Rebollo-González M, Díaz de la Pinta FJ, Morales-Gallego M, Rodríguez-Pinilla SM, Onaindia A.

Int J Mol Sci. 2025 Jun 19.26(12).

PMID: 40565334

FI: 4,9

http://dx.doi.org/10.3390/ijms26125871This link opens in a popup window


MET pathway inhibition increases chemo-immunotherapy efficacy in small cell lung cancer.

Del Rey-Vergara R, Galindo-Campos MA, Rocha P, Carpes M, Martínez C, Masfarré L, Menéndez S, Quimis F, Rossell A, Iñañez A, Pérez-Buira S, Rojo F, Gimeno R, Isla D, Zugazagoitia J, Martí Blanco C, García-Campelo R, Moreno-Vega A, León-Mateos L, Callejo Mellén Á, Park KS, Heeke S, Heymach JV, Taus Á, Paz-Ares L, Rovira A, Arriola E.

Cell Rep Med. 2025 Jun 13:102194.

PMID: 40543507

FI: 10,6

http://dx.doi.org/10.1016/j.xcrm.2025.102194This link opens in a popup window


Response to Sonidegib in Advanced Basal Cell Carcinomas by Histological Subtype: A Real-World Cohort.

Jiménez-Sánchez A, Muñoz Moreno-Arrones Ó, Béa-Ardebol S, Mayo-Martínez F, Pérez-Pastor G, Torres-Navarro I, Bonfill-Ortí M, Ruiz-Salas V, Masferrer E, Martos-Cabrera L, Deza G, Fernandez-de-Misa Cabrera R, Feal C, Turrión-Merino L, Toll A, Abril Pérez C, Botella Estrada R, Yébenes M, Galiano-Mejías S, Jiménez-Gallo D, Ferrandiz-Pulido C, Florez A, Hernández-Hernández N, Rios-Buceta L, Sanmartín O, Ciudad Blanco C, Jaka A, Just-Sarobé M, Conde-Taboada A, Mayor Arenal M, Vargas-Laguna E, Alcaraz León I, Leal L, Medina Montalvo S, Polo I, Hernández-Marín B, Soria A, Delgado-Jiménez Y, Rodríguez-Jiménez P.

Int J Dermatol. 2025 Jun 04.

PMID: 40468572

FI: 3,3

http://dx.doi.org/10.1111/ijd.17896This link opens in a popup window


Differential expression of proliferation and immune response genes between children and adults influences survival of diffuse large B cell lymphoma.

Mangiaterra T, Alonso-Alonso R, Rabinovich A, Herman D, De Dios Soler M, Galluzzo L, Soria M, Colli S, De Matteo E, Rodriguez Pinilla SM, Chabay P.

Sci Rep. 2025 Jun 03.15(1):19391.

PMID: 40461625

FI: 3,9

http://dx.doi.org/10.1038/s41598-025-04349-xThis link opens in a popup window


Unilateral Hyperhidrosis. Symptom of Thoracic Outlet Syndrome: 2-Case Review.

Mateos Rico JJ, Gutiérrez Pascual M, Sánchez Gilo A, Vicente Martín FJ.

Actas Dermosifiliogr. 2025 Jun.116(6):T657-T658.

PMID: 40174772

FI: 2,8

http://dx.doi.org/10.1016/j.ad.2025.03.020This link opens in a popup window


Early-Stage Mycosis Fungoides: Searching for biomarkers associated with advanced stage progression.

Rebollo-González M, Gargallo-Moneva V, Sánchez-Martínez A, Torre-Castro J, Herencia C, Moreno-Delgado M, Alonso-Alonso R, Manso R, Borregón J, Díaz de la Pinta FJ, Pajares R, Gotor-Rivera A, Torres-Navarro I, Morillo-Giles D, Moreno-Vílchez C, Martín-Torregrosa D, Muniesa C, Servitje O, Climent F, Frutos Díaz-Alejo J, Rivera-Díaz R, Ortiz-Romero PL, Rodríguez-Peralto JL, Rodríguez-Pinilla SM, Rodríguez M.

Br J Dermatol. 2025 May 27.

PMID: 40424592

FI: 10,6

http://dx.doi.org/10.1093/bjd/ljaf204This link opens in a popup window


New therapeutic approaches for EGFR mutated non-small cell lung cancer on osimertinib era.

Rubio-Perez J, Hernandez R, Santolaya C, Martin-Soberon MC, Zazo S, Carvajal N, Rojo F.

Cancer Treat Res Commun. 2025 May 16.44:100945.

PMID: 40414016

FI: 2,4

http://dx.doi.org/10.1016/j.ctarc.2025.100945This link opens in a popup window


High-Frequency Ultrasound Assessment of Skin Thickness Following Lipofilling in Facial Sclerosing Dermatoses: A Case Series.

Gomez-Martinez S, Fuertes I, Ferrer Fuertes A, Gonzalez FJC, Martí Pagés C, Lledó-Ibáñez GM, Espinosa G, Quintana-Codina M, Iglesias Sancho M, Cembrano MD, Bosch-Amate X, Mascaró JM, Giavedoni P.

J Cosmet Dermatol. 2025 May.24(5):e70229.

PMID: 40402871

FI: 2,5

http://dx.doi.org/10.1111/jocd.70229This link opens in a popup window


IL-17C and Pityriasis Rubra Pilaris: Successful Treatment of Erythroderma With Brodalumab.

Duperrier-Ruiz N, Recio-Monescillo M, Eraña-Tomás I, Del Carmen Fariña-Sabaris M, Mendoza-Cembranos MD, Requena-Caballero L.

Int J Dermatol. 2025 May 08.

PMID: 40344230

FI: 3,3

http://dx.doi.org/10.1111/ijd.17839This link opens in a popup window


V217F MYD88 mutation in low-grade B-cell lymphomas with plasmacytic differentiation: a diagnostic challenge.

Machuca Aguado JB, Alonso RM, Salgado RN, Castaño Bonilla T, León Del Campo M, Rodríguez Pinilla SM, Díaz de la Pinta FJ.

Pathology. 2025 Apr 07.

PMID: 40348703

FI: 3

http://dx.doi.org/10.1016/j.pathol.2025.02.006This link opens in a popup window


Pulse-Generator Rejection of Probable Allergic Origin in Deep Brain Stimulation: A Rare Complication Successfully Managed with a Polytetrafluoroethylene-Covered Device.

Ayerbe J, Barroso B, García-Ruiz PJ, Pastor-Nieto MA, Sastre J, Cabrera-Montes J.

Mov Disord Clin Pract. 2025 Apr 18.

PMID: 40248978

FI: 2,7

http://dx.doi.org/10.1002/mdc3.70086This link opens in a popup window


Inflammatory Fibroid Polyp (Vanek's Tumor): A Retrospective Multicentric Analysis of 67 Cases.

Sánchez MM, Domínguez-Prieto V, Qian Zhang S, Quiceno Arias HD, Álvarez Álvarez MB, Fuertes MJ, Meliga C, Jiménez-Galanes S, Labajo HG, Olmo DG, Campos PV.

Cancers (Basel). 2025 Apr 02.17(7).

PMID: 40227778

FI: 4,4

http://dx.doi.org/10.3390/cancers17071209This link opens in a popup window


BRCA1/2 and Other Predisposition Genes in High-Risk Hormone Receptor+/Human Epidermal Growth Factor Receptor 2- Breast Cancer Treated With Endocrine Therapy With or Without Palbociclib: A Secondary PENELOPE-B Study Analysis.

Hahnen E, Hauke J, Gelmon K, Marmé F, Ernst C, Martin M, Untch M, Bonnefoi H, Knudsen E, Im SA, DeMichele A, Van't Veer L, Kim SB, Bear H, McCarthy N, Rhiem K, Turner N, Witkiewicz A, Rojo F, Filipits M, Martin LA, Fasching PA, Schem C, Becker K, García-Sáenz JA, Kelly CM, Reimer T, Toi M, Rugo HS, Denkert C, Gnant M, Makris A, Liu Y, Valota O, Felder B, Weber K, Nekljudova V, Loibl S.

JCO Precis Oncol. 2025 Apr.9:e2400742.

PMID: 40209141

FI: 5,8

http://dx.doi.org/10.1200/PO-24-00742This link opens in a popup window


Clinical, Pathologic, and Molecular spectrum of Angioinmmunoblastic T-cell Lymphoma Cutaneous Lesions: Clinical, Pathologic, and Molecular Analysis.

Díaz de la Pinta FJ, Pérez-Guillermo Cuevas MÁ, Manso R, Torre Castro J, Astilleros Blanco de Cordova L, Saus C, Morillo Giles D, Requena Caballero L, Rodríguez Pinilla SM.

Am J Surg Pathol. 2025 Apr 01.49(4):403-410.

PMID: 39803901

FI: 4,2

http://dx.doi.org/10.1097/PAS.0000000000002355This link opens in a popup window


Involvement of microRNAs-449/FASN axis in response to trastuzumab therapy in HER2-positive breast cancer.

Lameirinhas A, Torres-Ruiz S, Garrido-Cano I, Hernando C, Martínez MT, Rovira A, Albanell J, Zazo S, Rojo F, Bermejo B, Lluch A, Cejalvo JM, Tormo E, Eroles P.

Mol Med. 2025 Mar 25.31(1):116.

PMID: 40133809

FI: 6,4

http://dx.doi.org/10.1186/s10020-025-01163-zThis link opens in a popup window


Dissecting CD47 expression in lymphoid neoplasms to inform precision immunotherapy with anti-CD47 phagocytic checkpoint blockade.

Marra A, Ramsay A, Chamberlain-Keene S, Soares G, Ponzoni M, Padmasri S, Rodriguez-Justo M, Pomplun S, Proctor I, Childerhouse A, Muntasser A, Cioce M, Fazio VM, Ott G, Piris M, Falini B, Marafioti T.

Haematologica. 2025 Mar 20.

PMID: 40109184

FI: 7,9

http://dx.doi.org/10.3324/haematol.2024.286864This link opens in a popup window


Haematopoietic stem cell transplant in cutaneous T-cell lymphomas: A multicentre propensity-score matched study.

Bejarano L, Grau-Pérez M, Paíno-Román M, Muret MPG, Morillo M, Muniesa C, Torre-Castro J, Estrach MT, Díez EA, Belloso RML, Peñate Y, Martínez-Mera C, Botella-Estrada R, Eceiza MJM, Ortiz Romero PL, Blanes M, Fernández-de-Misa R, Prieto-Torres L, Amer MEP, Iznardo H, Moreno-Vílchez C, Servitje O, García-Doval I, Cañueto J.

J Eur Acad Dermatol Venereol. 2025 Mar 11.

PMID: 40065681

FI: 8

http://dx.doi.org/10.1111/jdv.20638This link opens in a popup window


Implementing digital pathology: qualitative and financial insights from eight leading European laboratories.

Matias-Guiu X, Temprana-Salvador J, Garcia Lopez P, Kammerer-Jacquet SF, Rioux-Leclercq N, Clark D, Schürch CM, Fend F, Mattern S, Snead D, Fusco N, Guerini-Rocco E, Rojo F, Brevet M, Salto Tellez M, Dei Tos A, di Maio T, Ramírez-Peinado S, Sheppard E, Bannister H, Gkiokas A, Arpaia M, Ben Dhia O, Martino N.

Virchows Arch. 2025 Mar 08.

PMID: 40056197

FI: 3,1

http://dx.doi.org/10.1007/s00428-025-04064-yThis link opens in a popup window


Large B-cell lymphoma associated with fluid overload: two new case reports with molecular insights.

Pascual LP, Crespo FJD, López BBA, de Los Ángeles Pérez Saénz M, Alonso RM, Pinilla SMR, de la Pinta FJD.

Virchows Arch. 2025 Mar 06.

PMID: 40047901

FI: 3,1

http://dx.doi.org/10.1007/s00428-025-04068-8This link opens in a popup window


Should hydroxyisohexyl 3-cyclohexene carboxaldehyde (LYRAL) still be part of the standard patch test series?

Hernández Fernández CP, Borrego L, Giménez Arnau AM, Sanz Sánchez T, Carrascosa Carrillo JM, Zaragoza Ninet V, Serra Baldrich E, Miquel Miquel FJ, Silvestre Salvador JF, Córdoba Guijarro S, Sánchez Gilo A, Mercader García P, Navarro Triviño F, Tous Romero F, Rodríguez Serna M, Melé Ninot G, Ruiz González I, Gómez de la Fuente E, Pastor Nieto MA, Sánchez-Pedreño Guillén P, Sánchez Pérez J, Pereyra Rodríguez JJ, Gatica Ortega ME, González Pérez R, García Doval I, Gallego Descalzo MA.

Actas Dermosifiliogr. 2025 Feb 28.

PMID: 40024601

FI: 2,8

http://dx.doi.org/10.1016/j.ad.2024.10.063This link opens in a popup window


Adaptive Proteomic Changes in Protein Metabolism and Mitochondrial Alterations Associated with Resistance to Trastuzumab and Pertuzumab Therapy in HER2-Positive Breast Cancer.

Madoz-Gúrpide J, Serrano-López J, Sanz-Álvarez M, Morales-Gallego M, Rodríguez-Pinilla SM, Rovira A, Albanell J, Rojo F.

Int J Mol Sci. 2025 Feb 12.26(4).

PMID: 40004024

FI: 4,9

http://dx.doi.org/10.3390/ijms26041559This link opens in a popup window


Generalized Eczema as a Transient Paradoxical Adverse Effect of Dupilumab.

Betancor D, Valverde-Monge M, Díaz-Recuero JL, Jo-Velasco ME, Del Pozo V, Sastre J.

J Investig Allergol Clin Immunol. 2025 Feb 20:0.

PMID: 39977014

FI: 6,7

http://dx.doi.org/10.18176/jiaci.1051This link opens in a popup window


The Potential of Single-Transcription Factor Gene Expression by RT-qPCR for Subtyping Small Cell Lung Cancer.

Iñañez A, Del Rey-Vergara R, Quimis F, Rocha P, Galindo M, Menéndez S, Masfarré L, Sánchez I, Carpes M, Martínez C, Pérez-Buira S, Rojo F, Rovira A, Arriola E.

Int J Mol Sci. 2025 Feb 03.26(3).

PMID: 39941061

FI: 4,9

http://dx.doi.org/10.3390/ijms26031293This link opens in a popup window


Erythema, Localized Edema and Heat vs Forearm Perimeter Increase. Time to Revise the Consensus Recommendations on the Vortex Provocation Test in Vibratory Urticaria-Angioedema?

Gatica-Ortega ME, Sánchez-Albisua B, Arranz-Sánchez DM, Pérez-Tato B, Sánchez-Gilo A, Córdoba-Guijarro S, Ortiz-Frutos FJ, Hernández-Cano N, de la Fuente EG, Elosua-González M, Bergón-Sendín M, García-Martín C, Sanz-Sánchez T, Mazuela-Díez O, Torres-Aranda R, Vergara-de-la-Campa L, Marinero-Escobedo S, Alegre-Bailo A, Garrido-Ríos A, Tous-Romero F, Busto-Leis JM, Sarró-Fuente C, Rodríguez-Cuadrado FJ, García-Piqueras P, Beneyto P, Pastor-Nieto MA.

Actas Dermosifiliogr. 2025 Feb 10.

PMID: 39938775

FI: 2,8

http://dx.doi.org/10.1016/j.ad.2025.02.010This link opens in a popup window


Dynamics of molecular heterogeneity in high-risk luminal breast cancer-From intrinsic to adaptive subtyping.

Denkert C, Rachakonda S, Karn T, Weber K, Martin M, Marmé F, Untch M, Bonnefoi H, Kim SB, Seiler S, Bear HD, Witkiewicz AK, Im SA, DeMichele A, Pehl A, Van't Veer L, McCarthy N, Stiewe T, Jank P, Gelmon KA, García-Sáenz JA, Westhoff CC, Kelly CM, Reimer T, Felder B, Olivé MM, Knudsen ES, Turner N, Rojo F, Schmitt WD, Fasching PA, Teply-Szymanski J, Zhang Z, Toi M, Rugo HS, Gnant M, Makris A, Holtschmidt J, Nekljudova V, Loibl S.

Cancer Cell. 2025 Feb 10.43(2):232-247.e4.

PMID: 39933898

FI: 44,5

http://dx.doi.org/10.1016/j.ccell.2025.01.002This link opens in a popup window


Discordance, accuracy and reproducibility study of pathologists' diagnosis of melanoma and melanocytic tumors.

Haggenmüller S, Wies C, Abels J, Winterstein JT, Heinlein L, Nogueira Garcia C, Utikal JS, Wohlfeil SA, Meier F, Hobelsberger S, Gellrich FF, Sergon M, Hauschild A, French LE, Heinzerling L, Schlager JG, Ghoreschi K, Schlaak M, Hilke FJ, Poch G, Korsing S, Sarfert C, Berking C, Heppt MV, Erdmann M, Haferkamp S, Drexler K, Schadendorf D, Sondermann W, Goebeler M, Schilling B, Kather JN, Fröhling S, Llamas-Velasco M, Requena LC, Ferrara G, Fernandez-Figueras M, Fraitag S, Müller CSL, Starz H, Kutzner H, Barnhill R, Carr R, Resnik KS, Braun SA, Holland-Letz T, Brinker TJ.

Nat Commun. 2025 Jan 17.16(1):789.

PMID: 39824857

FI: 15,7

http://dx.doi.org/10.1038/s41467-025-56160-xThis link opens in a popup window


In Situ Tracking of TCRβ Isoforms for Detection of T Cell Clonality: Implication for Precision Diagnosis and Targeted Immunotherapy of T-Cell Neoplasms.

Manipadam MT, Marra A, Ramsay A, Padmasri S, Gosh A, Neves M, Bailey C, Pomplun S, Maciocia P, Cwynarski K, Ferrari M, Lao-Siriex P, Piris M, Falini B, Linch D, Rosenwald A, Pule M, Zamò A, Marafioti T.

Hematol Oncol. 2025 Jan.43(1):e70018.

PMID: 39655706

FI: 3,9

http://dx.doi.org/10.1002/hon.70018This link opens in a popup window


Projects, Contracts and Observational Studies

PUBLIC

Sources of public funding for projects being developed at the IIS-FJD:

_FINANCIACIÓN-261001_FINANCIACIÓN-261001

REFERENCE

PROJECT TITLE

PRINCIPAL RESEARCHER

TYPE OF PROJECT

TOTAL FUNDING

PI21/01724

ESTUDIO MOLECULAR INTEGRAL DEL LINFOMA T ANGIOINMUNOBLASTICO.

RODRIGUEZ PINILLA, MARIA SOCORRO

PROYECTOS DE INVESTIGACIÓN CLÍNICA. ISCIII

€87,120.00

PMP21/00015

MEDICINA DE PRECISIÓN GENÓMINCA EN NEOPLASIAS LINFOIDES (PREGENLIF)

RODRIGUEZ PINILLA, MARIA SOCORRO

PROYECTOS DE INVESTIGACIÓN CLÍNICA. ISCIII

€234,300.00

PI24/00160

CARACTERIZACIÓN PRECLÍNICA Y CLÍNICA DEL PAPEL DE LCOR Y DE LA VÍA DE SEÑALIZACIÓN HIPPO EN LA RESISTENCIA A LAS TERAPIAS ANTI-HER2 EN EL CÁNCER DE MAMA HER2-POSITIVO

ROJO TODO, FEDERICO

PROYECTOS DE INVESTIGACIÓN CLÍNICA. ISCIII

€306,250.00

PT23/00114

PLATAFORMAS ISCIII DE APOYO A LA I+D+I EN BIOMEDICINA Y CIENCIAS DE LA SALUD

ROJO TODO, FEDERICO

PLATAFORMAS. ISCIII

€810,840.00

CPP2024-011716

DECODER-7: DECODIFICACIÓN DEL GEN CCR7 PARA DESARROLLAR UN DIAGNÓSTICO DE ACOMPAÑAMIENTO PARA EL TRATAMIENTO PERSONALIZADO CON TERAPIA ANTI-CCR7 EN CÁNCERES DE LA SANGRE.

RODRIGUEZ PINILLA, MARIA SOCORRO

PROYECTOS DE INVESTIGACIÓN CLÍNICA. MINISTERIO

€188,930.00

S2022/BMD-7212

HACIA LA MEDICINA DE PRECISIÓN EN CÁNCER DE COLON: BIOMARCADORES, MICROAMBIENTE TUMORAL Y MICROBIOTA

ROJO TODO, FEDERICO

PROYECTOS DE INVESTIGACIÓN CLÍNICA. CAM

€75,900.00

FI22/00324

CONTRATO PFIS: MIRIAM MORALES GALLEGO

RODRIGUEZ PINILLA, MARIA SOCORRO

INVESTIGACIÓN PREDOCTORAL. ISCIII

€89,900.00

PEJ-2023-AI/SAL-GL-27249

CONTRATO AYUDANTE DE INVESTIGACIÓN CAM: CLAUDIA ARGUIÑANO HOLGUÍN

MADOZ GURPIDE, JUAN

INVESTIGACIÓN PREDOCTORAL. CAM

€47,964.58

PRIVATE

REFERENCE

PROJECT TITLE

PRINCIPAL RESEARCHER

TYPE OF PROJECT

2024.072

ER-POSITIVE, HER2-NEGATIVE, ESR1-MUTATED ADVANCED OR METASTATIC BREAST CANCER" ("EAP")

ROJO TODO, FEDERICO

RESEARCH PROJECTS

2025.013

PRESTACIÓN DE SERVICIOS - PROYECTO TAS ESPAÑA - GOC - MENARINI

ROJO TODO, FEDERICO

RESEARCH PROJECTS

2025.016

PRESTACIÓN DE SERVICIOS ANATOMIA PATOLÓGICA DETECCIÓN MUTACIONES ESR1

ROJO TODO, FEDERICO

RESEARCH PROJECTS

9757/003

CONTRATO MARCO DE PRESTACIÓN DE SERVICIOS GEICAM Y IIS-FJD

ROJO TODO, FEDERICO

RESEARCH PROJECTS

9757/021

DETERMINACIÓN DE "MUTACIONES PIK3CA EN TUMOR PRIMARIO (FFPE) COBAS PIK3CA MUTATION TEST PARA LOS EXONES 1, 4, 7, 9 Y 20. "EN BENEFICIO DE PACIENTES QUE PARTICIPAN EN EL ENSAYO CLÍNICO METALLICA" "STUDY TO EVALUATE THE EFFECT OF METFORMIN IN THE PREVENTION OF HYPERGLYCEMIA IN HR[+]/HER2[-] PIK3CA-MUTATED ADVANCED BREAST CANCER PATIENTS TREATED WITH ALPELISIB PLUS ENDOCRINE THERAPY EN ESPAÑA.

ROJO TODO, FEDERICO

RESEARCH PROJECTS

9757/028

SPANISH REAL-WORLD DATA (RWD) ANALYSIS OF BRCA1/2 GENE MUTATIONS AND HOMOLOGOUS RECOMBINATION DEFICIENCY (HRD) IN ADVANCED OVARIAN CANCER. PLATAFORMA ID-BRCA

ROJO TODO, FEDERICO

OBSERVATIONAL STUDIES

EO164-22_FJD

ESTUDIO DE VALIDACIÓN MULTICÉNTRICO DE HER2-LOW EN CÁNCER DE MAMA MEDIANTE ENSAYOS IMMUNOHISTOQUÍMICOS CON LAS PLATAFORMAS: HERCEPTEST (DAKO, AGILENT) Y VENTANA 4B5 (VENTANA MEDICAL SYSTEMS, ROCHE TISSUE DIAGNOSTICS)

ROJO TODO, FEDERICO

OBSERVATIONAL STUDIES

EOH042-24_FJD

IA DISTRIBUIDA PARA EL DIAGNÓSTICO Y TRATAMIENTO TEMPRANO DE ENFERMEDADES CON GRAN PREVALENCIA EN EL ENVEJECIMIENTO. (AI4HEALTHYAGING). HERRAMIENTAS DE PREDICCIÓN DEL RIESGO DE CÁNCER COLORRECTAL Y DE PRÓSTATA

ROJO TODO, FEDERICO

OBSERVATIONAL STUDIES

PIC226-24_FJD

KAPPA AND LAMBDA MRNA DUAL ISH ROUND ROBIN STAINING AND INTERPRETATION STUDY (RINKL).

RODRIGUEZ PINILLA, MARIA SOCORRO

RESEARCH PROJECTS

PIC173-24_FJD

ESTUDIO PILOTO SOBRE CÁNCER GÁSTRICO METASTÁSICO/AVANZADO EN ESPAÑA CON ÉNFASIS EN LAS CARACTERÍSTICAS PATOLÓGICAS Y EL ANÁLISIS DE LA EXPRESIÓN DE BIOMARCADORES: GENES DE REPARACIÓN DEL ADN, HER2 Y CLAUDINA 18.2

ROJO TODO, FEDERICO

RESEARCH PROJECTS

15826/005

ACTUALIZACION EN LINFOMAS CUTANEOS. V EDICIÓN (4 Y 5 DE ABRIL DE 2025, AULA MAGNA DEL HUFJD)

RODRIGUEZ PINILLA, MARIA SOCORRO

TRAINING / TEACHING

00400038

ESR1 LIQUID BIOPSY PRECEPTORSHIP 2025

ROJO TODO, FEDERICO

TRAINING / TEACHING

00400048

AZINGENIUS HRD PRECEPTORSHIP AZ

ROJO TODO, FEDERICO

TRAINING / TEACHING

00400073

SEMINARIO: UNLOCK HIGH DIMENSIONAL BIOLOGY WITH 5D MULTIOMICS (25 DE NOVIEMBRE DE 2025)

ROJO TODO, FEDERICO

TRAINING / TEACHING


Clinical trials

The clinical trials listed below were in the recruitment phase in 2023. If you are interested in participating in any of the currently open trials, more information is available on the website (https://ensayos.quironsalud.es/)


EudraCT Number

TITLE

PHASE

MC1

INT2

PRINCIPAL RESEARCHER

2019-004637-16

ENSAYO CLÍNICO PILOTO, UNICÉNTRICO, NO COMPARATIVO, PARA EVALUAR LA SEGURIDAD Y EFICACIA PRELIMINAR DE LA ADMINISTRACIÓ DE CÉLULAS MESENQUIMALES (MSCS) DERIVADAS DE TEJIDO ADIPOSO (MSCS-TA) INYECTADAS EN LOS BORDES DE LA ÚLCERA Y ENSAMBLADAS TRIDIMENSIONALMENTE EN UNA MATRIZ DE FIBRINA OBTENIDA A PARTIR PLASMA RICO EN PLAQUETAS (LÁMINAS DE MSCS-TA) EN PACIENTES CON HERIDAS CRÓNICAS REFRACTARIAS AL TRATAMIENTO CONVENCIONAL

II

YES

NO

NUÑEZ HIPOLITO LUCIA

2022-501753-36-00

ESTUDIO EN FASE III, DOBLE CIEGO, ALEATORIZADO, CONTROLADO CON PLACEBO, DE LA EFICACIA Y LA SEGURIDAD DEL POVORCITINIB (INCB054707) EN PARTICIPANTES CON HIDRADENITIS SUPURATIVA ENTRE MODERADA Y GRAVE (STOP-HS2)

III

YES

YES

CULLEN ARAVENA DANIELLA

2017-000873-35

ESTUDIO DE FASE 3, MULTICÉNTRICO, DOBLE CIEGO, EN EL QUE SE EVALÚAN LA SEGURIDAD Y LA EFICACIA A LARGO PLAZO DE BARICITINIB EN PACIENTES ADULTOS CON DERMATITIS ATÓPICA

III

YES

YES

VICENTE MARTIN FRANCISCO JAVIER

NA

ESTUDIO CLINICO ALEATORIZADO, DOBLE CIEGO Y CONTROLADO CON PLACEBO PARA EVALUAR LA EFICACIA DE UN PREPARADO PROBIOTICO ORAL EN EL TRATAMIENTO DE LA HIDRADENITIS SUPURATIVA

N/A

YES

YES

CULLEN ARAVENA DANIELLA

MC1: Multicentre INT2: International



Patents (revisar)

Title: Determination of methylation and levels of a miRNA in response to a platinum-based antitumour compound.

Application No: P201530997

Main entities: FIBHULP (83%), FIIS-FJD (17%), FCR (17%)

Inventors: Inmaculada Ibáñez Cáceres, Olga Pernía Arias, Javier de Castro Carpeño, Rosario Perona Abellón, Federico Rojo, Olga Vera Puente, Julia Jiménez Hernández.