Lipid Pathology: Clinical and Experimental (adults and children)

Lípidos-03
2025 DATA

Summary of activities

• Investigation of the potential causes involved in the development of obesity during childhood.
• Analysis of factors associated with the emergence of metabolic complications and increased cardiovascular risk in children and adolescents with obesity.
• Research into the influence of nutritional status on pubertal development.
• Evaluation of cardiovascular risk and excess weight in infants born small or large for gestational age.

Contributions to society

• Establishment of a specialised Paediatric Obesity Unit at Children's Hospital Fundación Jiménez Díaz, providing comprehensive care for children and adolescents with complex obesity.
• Design and implementation of the INFASEN ("Childhood with Meaning") Project aimed at the prevention of childhood and adolescent obesity.
• Delivery of educational talks on nutrition and healthy lifestyle habits in schools within the hospital's catchment area.
• Development of clinical guidelines for the diagnosis and treatment of pubertal disorders as part of the Puberty Working group of the Spanish Society of Paediatric Endocrinology.

Collaborations

• Puberty Working Group of the Spanish Society of Paediatric Endocrinology.
• Nutrition Working Group of the Spanish Atherosclerosis Society.
• Spanish Society of Adolescent Medicine.
• Prof. Ana Claudia Latronico, University of São Paulo, Brazil. Pioneer research group in the study of the molecular basis of precocious puberty.
• Prof. Alejandro Lomniczi, Division of Neuroscience, Oregon National Primate Research Centerer/OHSU, USA. This group is internationally recognised for its pioneering work on the epigenetic regulation of nutrition and puberty in experimental animal models.

PhD Theses

Lípidos-03

List of publications

Leptin-Independent Association Between SNVs in the Leptin Gene and HDL-C and Apo-AI in Children.

Pomares O, Pérez-Nadador I, Mejorado-Molano FJ, Parra-Rodríguez A, Soriano-Guillén L, Garcés C.

Int J Mol Sci. 2025 Dec 10.26(24).

PMID: 41465332

FI: 4,9

http://dx.doi.org/10.3390/ijms262411906

Differential DNA methylation in infants with IgE- and non-IgE-mediated cow's milk allergy and its association with acquired tolerance.

López-Gómez R, Gil-Martínez M, Ladrón-Guevara A, Rodrigo-Muñoz JM, Lorente-Sorolla C, Rodríguez-González D, García de Castro Z, Guillén-Sánchez G, Serrano-Santiago A, Mirasierra-Pérez R, Cañas JA, Del Río Camacho G, Del Pozo V.

Front Immunol. 2025.16:1571987.

PMID: 41394805

FI: 5,9

http://dx.doi.org/10.3389/fimmu.2025.1571987

The LMSz method - an automatable scalable approach to constructing gene-specific growth charts in rare disorders.

Low KJ, Foreman J, Hobson RJ, Kwuo H, Martinez-Cayuelas E, Almoguera B, Marin-Reina P, Caraffi SG, Garavelli L, Woods E, Balasubramanian M, Bayat A, Ockeloen CW, Wright CM, Firth HV, Cole TJ.

Eur J Hum Genet. 2025 Oct 13.

PMID: 41077617

FI: 4,6

http://dx.doi.org/10.1038/s41431-025-01947-1

I'm gonna make him a vaccine he can't refuse.

Piñeiro Pérez R.

An Pediatr (Engl Ed). 2025 Aug.103(2):503858.

PMID: 40784834

FI: 2,1

http://dx.doi.org/10.1016/j.anpede.2025.503858

Sleep-Wake Cycle and Circadian Misalignment in People With Autism Across the Lifespan With an Emphasis on Living Conditions.

Martínez-Cayuelas E, García-Muñoz AM, de Ocaña-Moreno MLS, Richdale AL, Gisbert-Gustemps L, Lugo-Marín J, Rodríguez-Morillas B, Peiró-Peiró AM, Victoria-Montesinos D, López-Anguas C, Meseguer-Illán MD, Ballester-Navarro P.

Autism Res. 2025 Jun 02.

PMID: 40452585

FI: 5,6

http://dx.doi.org/10.1002/aur.70058

Recommendations for the management of functional dyspepsia from the SEGHNP working group on motility and functional gastrointestinal disorders.

Carro Rodríguez MÁ, Hidalgo Montes I, Jovani Casano C, Recio Linares A, Masip Simó E, Rodrigo Garcia G, Bodas Pinedo A, en representación del Grupo de Trabajo de Motilidad y Trastornos Gastrointestinales funcionales de la SEGHNP.

An Pediatr (Engl Ed). 2025 May.102(5):503860.

PMID: 40379515

FI: 2,1

http://dx.doi.org/10.1016/j.anpede.2025.503860

Association of DLK1 SNPs with body mass index and plasma lipid levels in children.

Pomares O, Laborda J, Vales-Villamarín C, Pérez-Nadador I, Mejorado-Molano FJ, Parra-Rodríguez A, Mahillo-Fernández I, Soriano-Guillén L, Garcés C.

Pediatr Res. 2025 Mar 21.

PMID: 40113998

FI: 3,1

http://dx.doi.org/10.1038/s41390-025-04005-0

Diabetic foot infections in Internal Medicine services in Spain (2018-2022).

Fuentes Santos C, Rueda Camino JA, Asenjo Mota Á, Castaneda Pastor A, Zapatero Gaviria A, Canora Lebrato J, Barba-Martín R.

Rev Clin Esp (Barc). 2025 Mar.225(3):125-130.

PMID: 39864519

FI: 1,7

http://dx.doi.org/10.1016/j.rceng.2025.01.006

Can the total thrombus-formation analysis system predict bleeding risk in individuals with VWF levels between 30 and 50 IU/dL?

Revilla N, Vidal-Laso R, Velasco-Rodríguez D, Martínez-Alfonzo I, Martín-Herrero S, Hernández B, Llamas P.

Thromb Res. 2025 Mar.247:109260.

PMID: 39842330

FI: 3,4

http://dx.doi.org/10.1016/j.thromres.2025.109260

Reluctance of parents to immunize their children with nirsevimab.

Piñeiro Pérez R, Galán Arévalo S, Risso M, Hidalgo Montes I, López-Escobar A.

An Pediatr (Engl Ed). 2025 Feb 28:503743.

PMID: 40023672

FI: 2,1

http://dx.doi.org/10.1016/j.anpede.2025.503743

Factors associated with later toilet training and longer training times: A multicenter cross-sectional study.

Carro Rodríguez MÁ, Barrio Torres J, García Chaguaceda SB, Martínez Escribano B.

An Pediatr (Engl Ed). 2025 Feb.102(2):503709.

PMID: 39952852

FI: 2,1

http://dx.doi.org/10.1016/j.anpede.2025.503709