Data update as of 31/12/2025

6.4.2. GRUPO DE NEFROLOGÍA E HIPERTENSIÓN, PATOLOGÍA VASCULAR, Y DIABETES-220526-Laura-FOTO6.4.2. GRUPO DE NEFROLOGÍA E HIPERTENSIÓN, PATOLOGÍA VASCULAR, Y DIABETES-220526-Laura-FOTO
2025 DATA

Leaders

PIs

  • Sebastián Mas Fontao (Co-IP)
  • Jorge Oller Pedrosa
  • María Vanessa Pérez Gómez
  • Sandra Rayego Mateos

Research

  • Basic
  • Clinical

Location

Department of Nephrology and Hypertension. 3rd Floor
Fundación Jiménez Díaz University Hospital.

Avda. Reyes Católicos, 2. 28040 Madrid (Spain).


Nephrology and Hypertension, Vascular Disease and Diabetes Laboratory
4th Floor, Research Building and Basement Level (-1), Building 6
IIS-FJD. Fundación Jiménez Díaz University Hospital.

Avda. Reyes Católicos, 2. 28040 Madrid (Spain).


Keywords

Kidney disease, hypertension, atherosclerosis, chronic kidney disease, acute kidney injury, diabetes, and diabetic kidney disease.


Gender perspective

Nefrología-01Nefrología-01

Summary of activities

The group carries out multidisciplinary research focused on the mechanisms, diagnosis and treatment of renal, cardiovascular and metabolic diseases. Its main strategic research lines include:

  • Chronic kidney disease (CKD): identification of biomarkers of disease progression, inflammation, fibrosis and tubular injury.
  • Hypertension, atherosclerosis and vascular damage: investigation of pathophysiological mechanisms, vascular remodelling, arterial stiffness and endothelial dysfunction.
  • Diabetes mellitus, obesity and vascular complications: research into diabetic kidney disease, microvascular injury and associated cardiovascular risk.
  • Kidney-heart-metabolism interactions: study of the integrative mechanisms linking CKD, hypertension, diabetes and cardiovascular disease.
  • Precision medicine: risk stratification, genetics, proteomics and the identification of new therapeutic targets.

Contributions to society

The Group collaborates with national patient associations, including ALCER, and international organisations such as the European Kidney Patients’ Federation (EKPF), to improve the prevention, diagnosis and treatment of diabetes and renal and cardiovascular diseases.

Its contribution to society is reflected in its extensive scientific output, including more than 1,000 publications cited over 200,000 times, the development of more than 10 clinical practice guidelines, and the generation of more than 10 patents. The group is also actively involved in scientific societies and congresses and contributes to educational initiatives, including the development of the Renal MOOC and other training activities aimed at healthcare professionals, patients and the general public: https://www.edx.org/course/rinones-conoce-sus-funciones-para-mejorar-tu-saludThis link opens in a popup window


Collaborations

The group maintains numerous national and international collaborations within the framework of projects funded by the Spanish National R&D Plan, the European Union, and working groups belonging to national and international scientific societies. Among its main national collaborations are:

  • Spanish Renal Research Network (REDINREN): participation in multicentre projects focused on chronic kidney disease, biomarkers and renal protective therapies.
  • CIBERDEM and CIBERCV: collaborations on studies addressing diabetes, obesity, cardiovascular risk and inflammatory mechanisms.
  • University Hospitals in the Madrid Region (La Paz University Hospital, 12 de Octubre University Hospital, Ramón and Cajal University Hospital and Clínico San Carlos University Hospital): shared patient cohorts, clinical trials and translational research projects.
  • Autonomous University of Madrid (UAM): teaching activities, supervision of doctoral theses and joint biomedical research projects.
  • Biomedical Research Centres (CNIC, CNIO and IMDEA): mechanistic studies on inflammation, metabolism and vascular injury.

PhD Theses


Nefrología-02Nefrología-02

List of publications

Prevalence of primary aldosteronism and screening indications.

Ruiz-Sanchez JG.

Vitam Horm. 2026.130:43-67.

PMID: 41638804

FI: 0

http://dx.doi.org/10.1016/bs.vh.2025.08.001This link opens in a popup window


Fibrillary Glomerulonephritis in Systemic Lupus Erythematosus: A Case Series.

Ayehu G, Aguirre Polo MV, Yang Y, Wu M, Jhaveri KD.

Kidney Med. 2026 Feb.8(2):101225.

PMID: 41623306

FI: 3,4

http://dx.doi.org/10.1016/j.xkme.2025.101225This link opens in a popup window


The dominant driver paradigm of cardiometabolic care.

Hernandez Sevillano J, Babagoli MA, Chen Y, Liu SH, Mellacheruvu P, Johnson J, Ibanez B, Lorenzo O, Mechanick JI.

Am J Prev Cardiol. 2026 Feb.25:101389.

PMID: 41613359

FI: 5,9

http://dx.doi.org/10.1016/j.ajpc.2025.101389This link opens in a popup window


From Evidence to Action: Advancing Timely Implementation of Triple Therapy in Type 2 Diabetes Mellitus and CKD.

Fernandez-Fernandez B, Gorriz JL, Cebrian-Cuenca A, Fácila L, Fernandez Rodriguez JM, Maraver MP, Ortiz A.

Kidney Int Rep. 2026 Jan.11(1):6-16.

PMID: 41541781

FI: 5,7

http://dx.doi.org/10.1016/j.ekir.2025.09.027This link opens in a popup window


The Role of Aldosterone in Detecting Resistance-Driven Hypoaldosteronism and Deficit-Driven Hypoaldosteronism.

Ruiz-Sánchez JG, Calle-Pascual AL, Rubio-Herrera MÁ, De Miguel Novoa P, Gómez-Hoyos E, Runkle I.

J Clin Med. 2025 Dec 27.15(1).

PMID: 41517465

FI: 2,9

http://dx.doi.org/10.3390/jcm15010218This link opens in a popup window


A Pilot Study of Opportunistic Chronic Kidney Disease Screening in Primary Care Using a Clinical Decision Support System.

López-Garrigós M, Puig E, Sánchez S, Gutiérrez I, Salinas M, Ortiz A, Flores E.

Diagnostics (Basel). 2025 Dec 19.16(1).

PMID: 41515503

FI: 3,3

http://dx.doi.org/10.3390/diagnostics16010008This link opens in a popup window


The association between mineralocorticoid receptor antagonist use and diabetes occurrence and progression: A systematic review and meta-analysis.

Kanbay M, Guldan M, Ozbek L, Rustamov A, Gulmaliyev I, Ortiz A, Rossing P.

Br J Clin Pharmacol. 2025 Dec 30.

PMID: 41469771

FI: 3

http://dx.doi.org/10.1002/bcp.70433This link opens in a popup window


Comparing Age and Sex Specific Reference Values of Estimated Glomerular Filtration Rate between the United States and Europe.

Astley ME, Ortiz A, Hallan S, Gambaro G, Carrero JJ, Ebert N, Eriksen BO, Faucon AL, Ferraro PM, Ittermann T, Indridason OS, Rise Langlo KA, Melsom T, Rule AD, Schaeffner E, Stracke S, Palsson R, Jager KJ, Stel VS, Chesnaye NC.

Clin J Am Soc Nephrol. 2025 Dec 26.

PMID: 41452663

FI: 7,1

http://dx.doi.org/10.2215/CJN.0000000956This link opens in a popup window


Safeguarding Innovation in Dialysis-Rethinking the EU Medical Device Regulation.

Ferreira AC, Sezer S, Palladino G, Ortiz A.

Nephrol Dial Transplant. 2025 Dec 22.

PMID: 41427891

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf270This link opens in a popup window


Adherence to the Mediterranean Diet and frailty criteria in an old population with metabolic syndrome: A cross-sectional analysis.

Torrego-Ellacuría M, Cuesta-Triana F, Ortiz-Ramos M, Martínez-González MÁ, Corella D, Vázquez-Lorente H, Fitó M, Martínez JA, Tojal-Sierra L, Wärnberg J, Vioque J, Romaguera D, López-Miranda J, Estruch R, Tinahones FJ, Santos-Lozano JM, Serra-Majem JL, Bueno-Cavanillas A, Tur JA, Romero Vigara JC, Pintó X, Gaforio JJ, Vidal J, Mas-Fontao S, Daimiel L, Chiva-Blanch G, Basterra-Gortari J, Gutierrez L, Sorlí JV, Minguella Muñoz E, García-Rios A, Bernabé Casanovas A, Gómez-Gracia E, Zulet MA, Nafría M, Casas R, Garrido-Garrido EM, Goicolea-Güemez L, Gómez-Pérez AM, Ruiz-Canela M, Megias I, Valero-Barceló C, Montenegro Calvo M, Peña-Orihuela PJ, Tercero Maciá C, Razquín C, Babio N, Sala de Vedruna A, Barabash A, Matía-Martín P.

J Nutr Health Aging. 2025 Dec 17.30(2):100757.

PMID: 41411872

FI: 4

http://dx.doi.org/10.1016/j.jnha.2025.100757This link opens in a popup window


Gut microbiota modulation in GLP-1RA and SGLT-2i therapy: clinical implications and mechanistic insights in type 2 diabetes.

Kanbay M, Al-Shiab R, Shah E, Ozbek L, Guldan M, Ortiz A, Fouque D.

Clin Kidney J. 2025 Dec.18(12):sfaf351.

PMID: 41409228

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf351This link opens in a popup window


Understanding frailty across the kidney transplant continuum: a comprehensive systematic review of recent evidence.

Kanbay M, Fidan DG, Guldan M, Ozbek L, Abdel-Rahman SM, Ortiz A, Covic A.

Int Urol Nephrol. 2025 Dec 16.

PMID: 41402678

FI: 1,9

http://dx.doi.org/10.1007/s11255-025-04968-3This link opens in a popup window


Ovarian metastasis in a young woman with follicular thyroid carcinoma: A differential diagnosis with struma ovarii.

Tejedo-Flors D, Argüello-Gordillo T, Argente-Martínez E, López-Muñoz B, López-Mondéjar P.

Endocrinol Diabetes Nutr (Engl Ed). 2025 Dec 13:501676.

PMID: 41391968

FI: 1,8

http://dx.doi.org/10.1016/j.endien.2025.501676This link opens in a popup window


Second edition of the "do not do"" recommendations from the Spanish Society of Endocrinology and Nutrition (SEEN).

Díez JJ, Gargallo Fernández M, Gimeno Orna JA, González Arnaiz E, Huguet Moreno I, Martínez Couselo S, Miguélez González M, Ocón MJ, Pérez López G, Pita Gutiérrez F, Reverter Calatayud JL, Tejera Pérez C, Urgell Rull E, Fernández A.

Endocrinol Diabetes Nutr (Engl Ed). 2025 Dec 13:501687.

PMID: 41391967

FI: 1,8

http://dx.doi.org/10.1016/j.endien.2025.501687This link opens in a popup window


OBE-DIGITHUM: A Clinician-Led Digital Pathway for Sustainable Obesity Care-A Perspective.

Montoya T, Cárdenas JJ, Luca BL, Paniagua A, García-Valdecasas L, Reigosa L, Cruz S, Mas-Fontao S, Sierra R, Pérez de Arenaza V, Aganzo M, Gómez-Meana Á, Izquierdo I, Vázquez C.

Obes Rev. 2025 Dec 02:e70042.

PMID: 41330569

FI: 7,4

http://dx.doi.org/10.1111/obr.70042This link opens in a popup window


Understanding the social dimensions of kidney care pathways: A scoping review protocol.

Anokye R, Larkin J, Fehintola A, Eustace-Cook J, Martínez-Cadenas R, Duane B, Johnston B.

PLoS One. 2025.20(10):e0335597.

PMID: 41171735

FI: 2,6

http://dx.doi.org/10.1371/journal.pone.0335597This link opens in a popup window


Fish-eye disease. Altered HDL cholesterol metabolism and corneal involvement: A case report.

Álvarez ODogherty A, Rodríguez Jiménez C, Belanger-Quintana A, Rodríguez Novoa S, Arrieta Blanco F.

Endocrinol Diabetes Nutr (Engl Ed). 2025 Dec.72(10):501638.

PMID: 41102068

FI: 1,8

http://dx.doi.org/10.1016/j.endien.2025.501638This link opens in a popup window


Morphofunctional parameters as predictors of autologous hematopoietic stem cell transplantation outcomes.

Cornago J, Dassen C, Calderón C, Mahíllo I, Pardo L, López-Lorenzo JL, Hormigo AI, Caballero JC, Domingo-González A, Capellán R, Iturrate I, de Camino BP, Sánchez-Fernández MS, Teixeira Á, Del Pecho M, Llamas P, Solán L.

Front Nutr. 2025.12:1666754.

PMID: 41080170

FI: 5,1

http://dx.doi.org/10.3389/fnut.2025.1666754This link opens in a popup window


Clinical factors influencing the systolic blood pressure benefits of once-weekly semaglutide in patients with type 2 diabetes.

Ruiz-Sánchez JG, Sierra Poyatos RM, Luiza Luca B, Sánchez-Lechuga B, Modroño Móstoles N, Montoya Álvarez T, Meneses D, Sánchez-Lopez R, Casado Cases C, Pérez de Arenaza Pozo V, Vázquez C, Cárdenas-Salas JJ.

Med Clin (Barc). 2025 Dec.165(6):107179.

PMID: 41014747

FI: 2,1

http://dx.doi.org/10.1016/j.medcli.2025.107179This link opens in a popup window


Multidisciplinary Delphi study on residual risk in patients with chronic kidney disease and type 2 diabetes mellitus.

Ortiz A, Cebrián A, Soto A, Reyes A, Górriz JL.

Nefrologia (Engl Ed). 2025.45(7):501338.

PMID: 40945994

FI: 2,6

http://dx.doi.org/10.1016/j.nefroe.2025.501338This link opens in a popup window


Sex differences in (poly)phenol intake patterns and cardiovascular risk in Spanish adult population at high risk of cardiovascular disease: Cross-sectional findings.

Rubín-García M, Vitelli-Storelli F, Toledo E, Álvarez-Álvarez L, Martínez-González MÁ, Corella D, Salas-Salvadó J, Zomeño MD, Martínez JA, Alonso-Gómez ÁM, Wärnberg J, Vioque J, Romaguera D, López-Miranda J, Estruch R, Tinahones FJ, Santos-Lozano JM, Serra-Majem L, Bueno-Cavanillas A, Tur JA, Pintó X, Gaforio JJ, Matía-Martín P, Vidal J, Mas-Fontao S, Daimiel L, Ros E, Vázquez-Ruiz Z, Fernández de la Puente M, Álvarez-Sala A, Pérez-Vega A, García-Rios A, González-Palacios S, Gómez-Pérez AM, Zulet MÁ, Chaplin A, Casas R, Cano-Ibañez N, Tojal-Sierra L, Cueto-Galán R, Buil-Cosiales P, Gutiérrez-Carrasquilla L, Sorli JV, Malcampo M, Ortiz-Morales AM, Mira-Castejón LA, Rios S, Fitó M, Martín-Sánchez V, PREDIMED-PLUS Trial Investigators.

Nutrition. 2025 Dec.140:112919.

PMID: 40876090

FI: 3

http://dx.doi.org/10.1016/j.nut.2025.112919This link opens in a popup window


Excessive glycosylation drives thoracic aortic aneurysm formation through integrated stress response.

Rochano-Ortiz A, San Sebastián-Jaraba I, Zamora C, Simó C, García-Cañas V, Martínez-Albaladejo S, Fernández-Gómez MJ, Marcos-Ríos D, Martínez-Núñez P, Martín-Lorenzo M, Velho TR, Ruíz-Rodríguez MJ, Leal-Zafra A, Gabandé-Rodríguez E, Martínez-Martínez S, Guala A, Lorenzo Ó, Blanco-Colio LM, Martín-Ventura JL, Álvarez-Llamas G, Aldamiz-Echevarría G, Teixidó-Tura G, Forteza A, Nistal JF, Redondo JM, Méndez-Barbero N, Mittelbrunn M, Oller J.

Eur Heart J. 2025 Dec 01.46(45):4988-5005.

PMID: 40720766

FI: 35,7

http://dx.doi.org/10.1093/eurheartj/ehaf556This link opens in a popup window


Frailty Prevalence and Characterization Among Kidney Transplant Candidates in Spain: A Multicenter Study.

Pérez-Sáez MJ, Melilli E, Arias M, Franco A, Martínez R, Sancho A, Molina M, Facundo C, Polanco N, López V, Mazuecos A, Cabello S, González García ME, Suárez ML, Auyanet I, Espi J, García Falcón T, Ruiz JC, Galeano C, Artamendi M, Rodríguez-Ferrero ML, Portolés JM, Santana MA, Martín-Moreno PL, Arhda N, Calvo M, Mendiluce A, Macía M, Pérez-Tamajón ML, de Teresa J, Gascó B, Soriano S, Tabernero G, de la Vara L, Ramos AM, Martínez R, Montero de Espinosa E, Zalve JL, Pascual J, Rodríguez-Mañas L, Gutiérrez-Dalmau A, Moreso F.

Transpl Int. 2025.38:14098.

PMID: 40630784

FI: 3

http://dx.doi.org/10.3389/ti.2025.14098This link opens in a popup window


Aging with HIV: a cross-sectional look at comorbidities.

Montes MC, Rueda-Camino JA, Rallón N, Nistal-Juncos S, Barba Martín R.

Rev Clin Esp (Barc). 2025.225(6):502310.

PMID: 40348277

FI: 1,7

http://dx.doi.org/10.1016/j.rceng.2025.502310This link opens in a popup window


Hyperinflammation and Blindness. Screening for ROSAH Syndrome.

Tornero-Romero F, Sánchez-Hernandez R, Cantero-Del Olmo L, Saravia-Moya A, Gonzalez de Rivera-Utrera M, Sánchez-Barbero AI, Carreño-Salas E.

Eur J Case Rep Intern Med. 2025.12(4):004989.

PMID: 40270650

FI: 0

http://dx.doi.org/10.12890/2025_004989This link opens in a popup window


Nomenclature of renal involvement in diabetes mellitus: unify to manage diversity.

Marques M, Portolés J, Mora-Fernández C, Ortiz A, Navarro-González JF.

Front Med (Lausanne). 2025.12:1533011.

PMID: 40134917

FI: 3

http://dx.doi.org/10.3389/fmed.2025.1533011This link opens in a popup window


Diabetes Mellitus and Chronic Kidney Disease: The Future Is Being Surpassed.

Martínez-Castelao A, Górriz JL, Fernández-Fernández B, Soler MJ, Navarro-González JF.

J Clin Med. 2025 Nov 23.14(23).

PMID: 41375628

FI: 2,9

http://dx.doi.org/10.3390/jcm14238326This link opens in a popup window


Implementation of cervical ultrasound and related techniques in endocrinology and nutrition services in Spain. ECOSEEN 2025 study.

Reverter JL, Díaz Soto G, Martin T, Gargallo M, Sambo M, Argüelles I, Imaging and Associated Techniques Group of the Spanish Society of Endocrinology and Nutrition.

Endocrinol Diabetes Nutr (Engl Ed). 2025 Nov 26:501659.

PMID: 41309328

FI: 1,8

http://dx.doi.org/10.1016/j.endien.2025.501659This link opens in a popup window


Feasibility and Acceptability of the Cancer-Specific PRONTO Protocol for Nutritional Risk Screening in Outpatient Oncology Cancer Care: A Pilot Study.

Sánchez-Cabrero D, Rubio J, Durá Esteve J, Guzmán-Gómez L, Guzmán-Rolo G, Grande C, Martín Aguilar A, Pérez-Wert P, Pertejo A, Sulo S, Sharn AR, Palma Milla S, Dassen C, Muscaritoli M.

Cancers (Basel). 2025 Nov 19.17(22).

PMID: 41301062

FI: 4,4

http://dx.doi.org/10.3390/cancers17223697This link opens in a popup window


Historical Control Analysis Demonstrates Greater Long-Term Reduction in Plasma Globotriaosylceramide (Gb3) by Venglustat Compared With Placebo or Agalsidase Beta in Male Patients With Classic Fabry Disease.

Germain DP, DasMahapatra P, Liu S, Deegan P, Ortiz A, Modur V, Wilcox WR.

Mol Genet Genomic Med. 2025 Nov.13(11):e70152.

PMID: 41246852

FI: 1,6

http://dx.doi.org/10.1002/mgg3.70152This link opens in a popup window


Troxerutin is a novel osmotic agent for peritoneal dialysis with protective cardiovascular actions.

Kopytina V, Marchant V, Rodrigues-Diez R, Pascual-Antón L, Toggweiler N, Strahl L, Kane J, Tejera-Muñoz A, Cortés M, Sucunza D, Vaquero JJ, Vervloet M, Piecha D, Eringa EC, Ruiz-Ortega M, López-Cabrera M, González-Mateo GT.

Nephrol Dial Transplant. 2025 Nov 13.

PMID: 41231614

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf249This link opens in a popup window


Nutritional Strategies to Address Malnutrition in Dialyses Patients: A Systematic Review.

Arroyo-Serrano P, Alonso-Dominguez R, Mas-Fontao S, Gonzalez-Parra E, Sánchez-Tocino ML.

Nutrients. 2025 Nov 05.17(21).

PMID: 41228549

FI: 5

http://dx.doi.org/10.3390/nu17213478This link opens in a popup window


Global, regional, and national burden of chronic kidney disease in adults, 1990-2023, and its attributable risk factors: a systematic analysis for the Global Burden of Disease Study 2023.

GBD 2023 Chronic Kidney Disease Collaborators(Ortiz A).

Lancet. 2025 Nov 22.406(10518):2461-2482.

PMID: 41213283

FI: 88,5

http://dx.doi.org/10.1016/S0140-6736(25)01853-7This link opens in a popup window


New Kidneys, Old Risks: Cardiovascular Challenges After Transplantation.

Van Craenenbroeck AH, Chinnappa S, Dounousi E, Fernandez-Fernandez B, Iatridi F, Mark PB, Piko N, Stegbauer J, Torino C, Vogt L, Valdivielso JM.

Nephrol Dial Transplant. 2025 Nov 06.

PMID: 41206563

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf239This link opens in a popup window


The importance of disease coding following the diagnosis of chronic kidney disease: From ICD-10 code N18.9 to the role of clinical laboratories.

Troya MI, Bover J, Cia Hidalgo A, Malumbres S, Sánchez-Bayá M, Massó E, Coll-Brito V, Anton-Pampols P, da Silva I, Soler-Majoral J, Marcos E, Moreiras Abril B, Pérez-León N, Morera García M, Golf Zaragoza JP, Jusmet Miguel X, Lejardi Estevez Y, López-Alarcón R, Blanco I, Morales Indiano C, Gràcia-Garcia S, Buño Soto A, Górriz JL, Buades JM, Ortiz A, Sánchez E, Ara J.

Nefrologia (Engl Ed). 2025 Nov.45(9):501410.

PMID: 41203527

FI: 2,6

http://dx.doi.org/10.1016/j.nefroe.2025.501410This link opens in a popup window


Baseline Kidney Function, Albuminuria, and Urine Albumin-Creatinine Ratio Reduction with Finerenone, Empagliflozin, or Both: Post Hoc Analyses of CONFIDENCE Trial.

Mottl A, Scott C, Green JB, Heerspink HJL, Mann JFE, McGill JB, Nangaku M, Rosenstock J, Rossing P, Li L, Li N, Vaduganathan M, Agarwal R, CONFIDENCE Trial Investigators(Ortiz A).

J Am Soc Nephrol. 2025 Nov 06.

PMID: 41196655

FI: 9,4

http://dx.doi.org/10.1681/ASN.0000000928This link opens in a popup window


Kidney replacement therapy trajectories of patients with kidney failure: an ERA Registry study.

Boerstra BA, Kramer A, Jager KJ, Arnol M, Åsberg A, Bakkaloglu SA, Buchwinkler L, Crespo M, Ten Dam MAGJ, Finne P, García-Marcos SA, Heylen L, Hommel K, Indridason OS, Kuzema V, Lanot A, Methven S, Mutevelić-Turković A, Ponte B, Arévalo OLR, Valentin MO, Ortiz A, Stel VS, Ferraro PM.

Nephrol Dial Transplant. 2025 Nov 03.

PMID: 41183509

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf236This link opens in a popup window


Counterreply to the letter ""About the study of geriatric syndromes: the definition matters"".

Montes MC, Rueda-Camino JA, Rallón N, Nistal-Juncos S, Barba-Martín R.

Rev Clin Esp (Barc). 2025 Nov.225(9):502385.

PMID: 41167423

FI: 1,7

http://dx.doi.org/10.1016/j.rceng.2025.502385This link opens in a popup window


Trends in pulmonary embolism incidence in Spain (2016-2022): an analysis of differences among autonomous communities.

Gimena-Rodríguez FJ, Barba-Martín R, Angelina-García M, Trujillo-Luque D, Joya-Seijo MD, Rueda-Camino JA.

Rev Clin Esp (Barc). 2025 Nov.225(9):502377.

PMID: 41138975

FI: 1,7

http://dx.doi.org/10.1016/j.rceng.2025.502377This link opens in a popup window


Albuminuria-based universal screening for CKD should be implemented now in high-income countries.

Cordero L, Ortiz A.

Kidney Int. 2025 Nov.108(5):754-759.

PMID: 40907890

FI: 12,6

http://dx.doi.org/10.1016/j.kint.2025.04.037This link opens in a popup window


Impact of the Type of Dialysate Acid Concentrate Container on the Environmental Footprint of Hemodialysis Centers.

Martínez-Cadenas R, Audije-Gil J, Arenas MD, Vaquero NM, Portillo J, Larkin J, Fehintola A, Ortiz A, Duane B.

Am J Kidney Dis. 2025 Nov.86(5):616-623.e1.

PMID: 40738182

FI: 8,8

http://dx.doi.org/10.1053/j.ajkd.2025.06.009This link opens in a popup window


Circulating and Urinary CCL20 in Human Kidney Disease.

Molina-Cazallas N, García-Ayuso D, Fernández-Fernández B, Rodríguez-Osorio L, Sanchez-Rodriguez J, Pérez-Gómez MV, Ortiz A, Ramos AM.

Int J Mol Sci. 2025 Oct 30.26(21).

PMID: 41226600

FI: 4,9

http://dx.doi.org/10.3390/ijms262110563This link opens in a popup window


Exploring the Challenges and Opportunities of ChatGPT in University Teaching for Health Sciences: A Narrative Review.

Arroyo-Bello E, González-Toledo B, Abad-Valle J, Rodríguez-Gómez P, Garrigues-Ramón M.

Cureus. 2025 Oct.17(10):e94259.

PMID: 41216045

FI: 1,3

http://dx.doi.org/10.7759/cureus.94259This link opens in a popup window


Time trends in home dialysis: ERA Registry Figure of the month.

Stel VS, Ortiz A, Kramer A.

Clin Kidney J. 2025 Oct.18(10):sfaf325.

PMID: 41190265

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf325This link opens in a popup window


Kidney replacement therapy for men and women according to the ERA Registry and the USRDS.

Stel VS, Chesnaye NC, Boenink R, Boerstra BA, Astley ME, Methven S, Heylen L, Resic H, Ten Dam MAGJ, Hommel K, Solbu MD, Roblero MFS, Aresté-Fosalba N, Radunovic D, López HG, Buchwinkler L, Guidotti R, Lassalle M, Santiuste C, Stendahl M, Indridason OS, Escribá A, Bouzas-Caamaño ME, Arévalo OLR, Moustakas G, Vargas HH, Ortiz A, Kramer A.

Nephrol Dial Transplant. 2025 Oct 31.

PMID: 41172240

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf233This link opens in a popup window


Impact of switching from the CKD-EPI2009 to the EKFC equation on the epidemiology of chronic kidney disease and nephrology workload.

Villalvazo P, Molinero-Casares LM, Ortiz A.

Clin Kidney J. 2025 Oct.18(10):sfaf278.

PMID: 41158188

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf278This link opens in a popup window


Bridging the gap: recommendations to accomplish transition from pediatric to adult care in adolescents living with obesity.

Goday A, Pérez G, Fernández A, Díaz-Carrasco X, Leis R, de Hollanda A, Ramon-Krauel M.

Rev Endocr Metab Disord. 2025 Oct 21.

PMID: 41118079

FI: 8

http://dx.doi.org/10.1007/s11154-025-09998-xThis link opens in a popup window


Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.

GBD 2023 Causes of Death Collaborators(Ortiz A).

Lancet. 2025 Oct 18.406(10513):1811-1872.

PMID: 41092928

FI: 88,5

http://dx.doi.org/10.1016/S0140-6736(25)01917-8This link opens in a popup window


Global age-sex-specific all-cause mortality and life expectancy estimates for 204 countries and territories and 660 subnational locations, 1950-2023: a demographic analysis for the Global Burden of Disease Study 2023.

GBD 2023 Demographics Collaborators(Ortiz A).

Lancet. 2025 Oct 18.406(10513):1731-1810.

PMID: 41092927

FI: 88,5

http://dx.doi.org/10.1016/S0140-6736(25)01330-3This link opens in a popup window


Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.

GBD 2023 Disease and Injury and Risk Factor Collaborators.

Lancet. 2025 Oct 18.406(10513):1873-1922.

PMID: 41092926

FI: 88,5

http://dx.doi.org/10.1016/S0140-6736(25)01637-XThis link opens in a popup window


Mineralocorticoid receptor antagonist pre-adrenalectomy in primary aldosteronism.

Goi J, Paja Fano M, Rizo Gellida A, González-Boillos M, Martín Rojas-Marcos P, Caja Guayerbas L, García Cano AM, Ruiz-Sanchez JG, Vicente A, Gómez-Hoyos E, Recasens M, Barahona San Millan R, Picón César MJ, Díaz Guardiola P, Perdomo CM, Manjón-Miguélez L, Rebollo Román Á, Robles Lázaro C, Recio-Cordova JM, Calatayud M, Jiménez López N, Sampedro Nuñez M, Mena Ribas E, Sanmartín Sánchez A, Gonzalvo Diaz C, Lamas C, Serrano J, Michalopoulou T, Tenes Rodrigo S, Pascual-Corrales E, Jaén Aguila F, Muñoz Rivas N, Moya Mateo EM, Gutiérrez-Medina S, Hanzu FA, Parra Ramírez P, Araujo-Castro M.

J Clin Endocrinol Metab. 2025 Oct 04.

PMID: 41045519

FI: 5,1

http://dx.doi.org/10.1210/clinem/dgaf545This link opens in a popup window


Urinary tartaric acid and cardiovascular disease risk.

Ortiz A.

Eur Heart J. 2025 Oct 03.

PMID: 41042973

FI: 35,7

http://dx.doi.org/10.1093/eurheartj/ehaf760This link opens in a popup window


Comorbidity and Malnutrition as Key Determinants of Mortality in Elderly Haemodialysis Patients: A One-Year Observational Study.

Sanchez-Tocino ML, Mas-Fontao S, González-Parra E, Manso P, Burgos M, Carneiro D, Pereira M, Pereira C, Lopez-González A, Arenas MD, on behalf the renal foundation work team.

J Cachexia Sarcopenia Muscle. 2025 Oct.16(5):e70062.

PMID: 40990164

FI: 9,1

http://dx.doi.org/10.1002/jcsm.70062This link opens in a popup window


Attention deficit hyperactivity disorder risk, mental health diagnoses and experience of discrimination in transgender adolescents and youth.

Martínez Del Río C, Cuellar-Flores I, López de Lara D, Castañeda-Vozmediano R, Miguélez González M, Gaitero Pérez A, Pérez Rodríguez O, García Ron A.

Endocrinol Diabetes Nutr (Engl Ed). 2025 Oct.72(8):501593.

PMID: 40946028

FI: 1,8

http://dx.doi.org/10.1016/j.endien.2025.501593This link opens in a popup window


Rapidly Growing Thyroid Masses in Adults: Urgent Diagnostic Challenges and Effective Management-Single-Center Experience and Literature Review.

Miguélez González M, Fernández Sánchez Á, Álvarez Álvarez MB, Quiceno Arias HD, Osorio Silla I.

World J Surg. 2025 Oct.49(10):2777-2781.

PMID: 40879557

FI: 2,5

http://dx.doi.org/10.1002/wjs.70063This link opens in a popup window


STING inhibition alleviates experimental peritoneal damage: potential therapeutic relevance for peritoneal dialysis.

Marchant V, García-Giménez J, González-Mateo GT, Sandoval P, Tejedor-Santamaria L, Rayego-Mateos S, Ramos R, Jiménez-Heffernan JA, Ortiz A, Raby AC, López-Cabrera M, Ramos AM, Ruiz-Ortega M.

J Pathol. 2025 Oct.267(2):196-212.

PMID: 40810380

FI: 5,2

http://dx.doi.org/10.1002/path.6462This link opens in a popup window


The environmental and genetic architectures of ageing and CKD.

Sanchez-Niño MD, Byrska JK, Ortiz A.

Nephrol Dial Transplant. 2025 Oct 30.40(11):2008-2010.

PMID: 40794941

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf146This link opens in a popup window


Differences in histopathologic features and diagnostic performance of 99mTc-methoxy-isobutyl-isonitrol single photon emission tomography-CT and 18F-fluorocholine positron emission tomography-CT in primary hyperparathyroidism.

Osorio-Silla I, González DM, Quiceno Arias HD, Peinado PP, Cárdenas Salas JJ, González MM, Pestana Soares CA, Martínez Ruiz LF, Landaeta Kancev LC, Dhier LM, Escanciano M, Sánchez de Molina ML, Ruíz AP, Campos PV.

Surgery. 2025 Oct.186:109595.

PMID: 40782725

FI: 2,7

http://dx.doi.org/10.1016/j.surg.2025.109595This link opens in a popup window


10 tips on how to take a proper family history in CKD patient care.

Cornec-Le Gall E, van Eerde AM, Figueres L, Simons M, Capasso G, Perez Gomez MV, Nijenhuis T, Sayer JA, Zagorec N, Müller RU, Halbritter J.

Clin Kidney J. 2025 Sep.18(9):sfaf253.

PMID: 41140976

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf253This link opens in a popup window


Time trends in preemptive kidney transplantation in Europe: ERA Registry Figure of the month.

Stel VS, Ortiz A, Kramer A.

Clin Kidney J. 2025 Sep.18(9):sfaf304.

PMID: 41080616

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf304This link opens in a popup window


Finerenone: Evidence for benefit in Early Stages of Cardiovascular-Kidney-Metabolic Syndrome.

Márquez DF, Ortiz A, González-Moreno D, Ruilope LM, Ruiz-Hurtado G.

Cardiorenal Med. 2025 Sep 25:1-15.

PMID: 41036653

FI: 2,9

http://dx.doi.org/10.1159/000548494This link opens in a popup window


But how green is it actually? Calculating the environmental footprint of kidney care environmental optimizations within haemodialysis.

Duane B, Larkin J, Caiazzo M, Arenas M, Griffin A, Audije-Gil J, Mortimer F, Attwell H, Yasar A, Martínez-Cadenas R, Arias-Guillén M, Gomez M, Fehintola A, Steinbach I, Ortiz A.

Clin Kidney J. 2025 Sep.18(9):sfaf220.

PMID: 41030566

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf220This link opens in a popup window


Global Effect of Cardiovascular Risk Factors on Lifetime Estimates.

Cordero L, Abasheva D, Ortiz A.

N Engl J Med. 2025 Sep 25.393(12):1246-1247.

PMID: 40991917

FI: 78,5

http://dx.doi.org/10.1056/NEJMc2511206This link opens in a popup window


Increased tumor necrosis factor-receptor superfamily plasma levels are associated with early renal or retinal involvement in intermediate hyperglycemia.

Mas-Fontao S, Civantos E, Boukichou-Abdelkader N, Moreno JA, Gomez-Guerrero C, Gálvez MIL, Tuomilehto J, Lind M, Gabriel R, Egido J.

World J Diabetes. 2025 Sep 15.16(9):106002.

PMID: 40980291

FI: 4,6

http://dx.doi.org/10.4239/wjd.v16.i9.106002This link opens in a popup window


Transition of patients with hereditary nephropathies from pediatric to adult care.

Gomez MVP, Costea GC, Claus L, Gall EC, van Eerde AM, Lemoine S, Groothoff J, Levtchenko E, Klein L, Pape L, Müller RU, Liebau MC.

Nephrol Dial Transplant. 2025 Sep 10.

PMID: 40928490

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf186This link opens in a popup window


Plasma Interleukin 22 Predicts Progression of Early Diabetic Kidney Disease.

Fernandez-Fernandez B, Hasegawa T, Saruta Y, Li Guan Y, Sanz AB, Sanchez-Niño MD, Ramos AM, Sanchez-Rodriguez J, Navarro-Gonzalez JF, Ortiz A.

Am J Nephrol. 2025 Sep 08:1-13.

PMID: 40920595

FI: 3,2

http://dx.doi.org/10.1159/000547738This link opens in a popup window


Identification of early predictors of clinical remission in primary membranous nephropathy: a post hoc analysis of the STARMEN trial.

Rojas-Rivera JE, Caravaca-Fontán F, van de Logt AE, Sevillano A, Shabaka A, Ávila A, Rabasco C, Cabello V, Ortiz A, Quintana LF, Goicoechea M, Diaz M, Ronco P, Wetzels J, Fernández-Juárez G, Praga M.

Clin Kidney J. 2025 Sep.18(9):sfaf256.

PMID: 40900938

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf256This link opens in a popup window


Phthalate exposure is associated with subclinical coronary atherosclerosis: The Aragon Workers' Health Study (AWHS).

Mérida DM, Torrijo-Belanche C, Moreno-Franco B, Laclaustra M, Rey-García J, Gimeno-Ruiz S, Bayán-Bravo A, Guallar-Castillón P.

Am J Prev Cardiol. 2025 Sep.23:101072.

PMID: 40831762

FI: 5,9

http://dx.doi.org/10.1016/j.ajpc.2025.101072This link opens in a popup window


Trends in Home Dialysis Over the Last Decade in Europe: an ERA Registry Study.

Slon-Roblero MF, Stel VS, Sanchez-Alvarez E, Escola JM, Dias BJF, Auñón AS, Ferraro PM, De Meester JM, Boyer A, Rydell H, Hommel K, Åsberg A, Arias IR, Methven S, Huete MJE, Abrahams AC, Palsson R, Goffin E, Aresté-Fosalba N, Bello AJ, Kuzema V, Helve J, Kerschbaum J, Bakkaloglu SA, Kislikova M, Jager KJ, Ortiz A, Kramer A.

Nephrol Dial Transplant. 2025 Aug 29.

PMID: 40880108

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf171This link opens in a popup window


67 national-level factors potentially related to the incidence of kidney replacement therapy across Europe.

Pella E, Boenink R, Kramer A, Jager KJ, Ortiz A, Stel VS.

Nephrol Dial Transplant. 2025 Aug 28.

PMID: 40874760

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf163This link opens in a popup window


Association Between Oxidative-Inflammation Biomarkers and Incident Chronic Kidney Disease in People with High Cardiovascular Risk: A Nested Case-Control Study.

Quetglas-Llabrés MM, Díaz-López A, Bouzas C, Monserrat-Mesquida M, Salas-Salvadó J, Ruiz-Canela M, Martínez JA, Santos-Lozano JM, García S, Estruch R, López-Miranda J, Romaguera D, Tinahones FJ, García-Fernández M, Mas-Fontao S, Matía-Martín P, Vioque J, Bueno A, Babio N, Tur JA, Sureda A.

Antioxidants (Basel). 2025 Aug 08.14(8).

PMID: 40867871

FI: 6,6

http://dx.doi.org/10.3390/antiox14080975This link opens in a popup window


Varying mortality risks among patients with primary glomerular disease starting kidney replacement therapy: ERA Registry Figure of the month.

Stel VS, Ortiz A, Kramer A.

Clin Kidney J. 2025 Aug.18(8):sfaf237.

PMID: 40861383

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf237This link opens in a popup window


Comparison of an Energy-Reduced Mediterranean Diet and Physical Activity Versus an Ad Libitum Mediterranean Diet in the Prevention of Type 2 Diabetes : A Secondary Analysis of a Randomized Controlled Trial.

Ruiz-Canela M, Corella D, Martínez-González MÁ, Babio N, Martínez JA, Forga L, Alonso-Gómez ÁM, Wärnberg J, Vioque J, Romaguera D, López-Miranda J, Estruch R, Santos-Lozano JM, Serra-Majem L, Bueno-Cavanillas A, Tur JA, Martín-Sánchez V, Riera-Mestre A, Delgado-Rodríguez M, Matía-Martín P, Vidal J, Vázquez C, Daimiel L, Buil-Cosiales P, Shyam S, Sorlí JV, Castañer O, García-Rios A, Torres-Collado L, Gómez-Gracia E, Zulet MÁ, Konieczna J, Casas R, Cano-Ibáñez N, Tojal-Sierra L, Bernal-López RM, Toledo E, García-Gavilán J, Fernández-Carrión R, Goday A, Arenas-Larriva AP, González-Palacios S, Schröder H, Ros E, Fitó M, Hu FB, Tinahones FJ, Salas-Salvadó J.

Ann Intern Med. 2025 Aug 26.

PMID: 40854218

FI: 15,4

http://dx.doi.org/10.7326/ANNALS-25-00388This link opens in a popup window


In silico prediction of optimal multifactorial intervention in chronic kidney disease.

Latosinska A, Mina IK, Nguyen TMN, Golovko I, Keller F, Mayer G, Rossing P, Staessen JA, Delles C, Beige J, Glorieux G, Clark AL, Schanstra JP, Vlahou A, Peter K, Rychlík I, Ortiz A, Campbell A, Rupprecht H, Persson F, Mischak H, Siwy J.

J Transl Med. 2025 Aug 21.23(1):943.

PMID: 40842026

FI: 7,5

http://dx.doi.org/10.1186/s12967-025-06977-3This link opens in a popup window


How to interpret the number needed to treat for clinicians.

Chesnaye NC, Ortiz A, van Diepen M, Dekker F, Zoccali C, Tripepi G, Jager KJ, Stel VS.

Nephrol Dial Transplant. 2025 Aug 21.

PMID: 40839106

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf168This link opens in a popup window


Lorundrostat Efficacy and Safety in Uncontrolled Hypertension.

Burgos E, Fernández Fernández B, Ortiz A.

N Engl J Med. 2025 Aug 14.393(7):725-726.

PMID: 40802954

FI: 78,5

http://dx.doi.org/10.1056/NEJMc2507996This link opens in a popup window


Effects of oral semaglutide on kidney outcomes in people with type 2 diabetes: a nationwide, multicentre, retrospective, observational study (Renal_ENDO2S-RWD substudy).

Moreno-Pérez O, Reyes-Garcia R, Guillen-Morote C, Doulatram-Gamgaram VK, Casado Cases C, Arias Mendoza N, Tejera-Pérez C, Cárdenas-Salas J, Martínez-Fuster S, Lardiés-Sánchez B, Márquez-Pardo R, Pinés P, Tejera-Muñoz A, Fernández-García JC, Modrego-Pardo I.

Clin Kidney J. 2025 Aug.18(8):sfaf227.

PMID: 40800212

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf227This link opens in a popup window


Changing from the CKD-EPI to the EKFC creatinine equation to estimate glomerular filtration rate in adults in a Northern European health system.

Russel WA, Fu EL, Creon A, Faucon AL, Caldinelli A, Bouwmans P, Inker LA, Delanaye P, Pottel H, Ortiz A, Levey AS, Carrero JJ.

Nephrol Dial Transplant. 2025 Aug 11.

PMID: 40796100

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf148This link opens in a popup window


Evolving strategies for early diagnosis, proactive prevention and treatment of CKD.

Ortiz A, Yanagita M, Yokoi H, Torra R.

Nephrol Dial Transplant. 2025 Aug 08.

PMID: 40795360

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf151This link opens in a popup window


From pathophysiology to novel approaches for obesity-associated hypertension.

Kanbay M, Yayci E, Genc C, Copur S, Aktas O, Sarafidis P, Covic A, Ortiz A, Laffin LJ.

Clin Kidney J. 2025 Aug.18(8):sfaf218.

PMID: 40761303

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf218This link opens in a popup window


Global, regional, and national prevalence of kidney failure with replacement therapy and associated aetiologies, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.

GBD 2023 Kidney Failure with Replacement Therapy Collaborators(Ortiz A).

Lancet Glob Health. 2025 Aug.13(8):e1378-e1395.

PMID: 40712611

FI: 18

http://dx.doi.org/10.1016/S2214-109X(25)00198-6This link opens in a popup window


Sex-based differences in access to reperfusion therapies for pulmonary embolism in Spain during the 2016-2022 period.

Rueda-Camino JA, Angelina-García M, Trujillo-Luque D, Joya-Seijo MD, Teigell-Prieto L, Novalbos-Partida JÁ, Gimena-Rodríguez FJ, Barba-Martín R.

Thromb Res. 2025 Aug.252:109371.

PMID: 40479910

FI: 3,4

http://dx.doi.org/10.1016/j.thromres.2025.109371This link opens in a popup window


Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes.

Agarwal R, Green JB, Heerspink HJL, Mann JFE, McGill JB, Mottl AK, Rosenstock J, Rossing P, Vaduganathan M, Brinker M, Edfors R, Li N, Scheerer MF, Scott C, Nangaku M, CONFIDENCE Investigators(Ortiz A).

N Engl J Med. 2025 Aug 07.393(6):533-543.

PMID: 40470996

FI: 78,5

http://dx.doi.org/10.1056/NEJMoa2410659This link opens in a popup window


Rationale and design of the Renal Lifecycle trial assessing the effect of dapagliflozin on cardiorenal outcomes in severe chronic kidney disease.

Bakker WM, Heerspink HJL, Berger SP, Wanner C, Badve SV, Arnott C, Abrahams AC, van den Born JC, van Faassen TC, Gaillard CAJM, Gelens MACJ, Górris JL, Hemmelder MH, Jakulj L, van Kruijsdijk RCM, Kuypers DRJ, van der Meer P, van der Net JB, Nijmeijer HH, Vervloet MG, de Vries APJ, Walsh M, Wang AY, Gansevoort RT, Renal Lifecycle Trial Investigators (Ortiz A).

Nephrol Dial Transplant. 2025 Aug 29.40(9):1746-1755.

PMID: 40053493

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf046This link opens in a popup window


External validation of the S-GRAS score for predicting recurrence in patients with adrenocortical carcinoma: implications for adjuvant mitotane therapy.

Jimenez-Fonseca P, Álvarez-Escola C, Ballester Navarro I, Hernando Cubero J, González Fernández L, Mangas Cruz MÁ, Iglesias C, García-Donas J, Picón MJ, Paja M, González Batanero L, García L, Molina J, Jimeno Maté R, Aller J, Romero MDCT, Cardenas Salas J, Gutiérrez-Buey G, Egaña Zunzunegui N, Navarro M, Lecumberri MJ, Valdés N, Carmona-Bayonas A.

Eur J Endocrinol. 2025 Jul 31.193(2):320-328.

PMID: 40810251

FI: 5,2

http://dx.doi.org/10.1093/ejendo/lvaf171This link opens in a popup window


High Levels of Galectin-3 and Uric Acid Are Independent Predictors of Renal Impairment in Patients with Stable Coronary Artery Disease.

Leal-Pérez N, Blanco-Colio LM, Martín-Ventura JL, Gutiérrez-Landaluce C, Mahíllo-Fernández I, González-Casaus ML, Lorenzo Ó, Egido J, Tuñón J.

J Clin Med. 2025 Jul 25.14(15).

PMID: 40806886

FI: 2,9

http://dx.doi.org/10.3390/jcm14155264This link opens in a popup window


Living and deceased donor kidney transplant rates across Europe: ERA Registry Figure of the month.

Stel VS, Ortiz A, Kramer A.

Clin Kidney J. 2025 Jul.18(7):sfaf236.

PMID: 40799934

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf236This link opens in a popup window


Efficacy and safety of medical treatment of primary aldosteronism: a real-world data study in Spain.

Goi J, Paja Fano M, Rizo Gellida A, González-Boillos M, Rojas-Marcos PM, Caja Guayerbas L, García Cano AM, Ruiz-Sanchez JG, Vicente A, Gómez-Hoyos E, Recasens M, Barahona San Millan R, Picón César MJ, Díaz Guardiola P, Perdomo CM, Manjón-Miguélez L, Rebollo Román Á, Robles Lázaro C, Recio JM, Calatayud M, Jiménez López N, Sampedro Nuñez M, Ribas EM, Sanmartín Sánchez A, Diaz CG, Lamas C, Serrano J, Michalopoulou T, Rodrigo ST, Pascual-Corrales E, Aguila FJ, Muñoz Rivas N, Moya Mateo EM, Gutiérrez-Medina S, Hanzu FA, Parra Ramírez P, Araujo-Castro M.

Eur J Endocrinol. 2025 Jul 31.193(2):297-309.

PMID: 40743244

FI: 5,2

http://dx.doi.org/10.1093/ejendo/lvaf158This link opens in a popup window


Myocardial Ischaemic Syndromes in Chronic Kidney Disease: Risky Pathways from Non-Acute to Acute Events.

Zoccali C, Chinnappa S, Fernández-Fernández B, Iatridi F, Mallamaci F, Mark PB, Ntounousi E, Piko N, Stegbauer J, Torino C, Valdivielso JM, Van Craenenbroeck A, Vogt L, De Caterina R.

Nephrol Dial Transplant. 2025 Jul 30.

PMID: 40736534

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf142This link opens in a popup window


Clinical Effectiveness of Oral Semaglutide in Women with Type 2 Diabetes: A Nationwide, Multicentre, Retrospective, Observational Study (Women_ENDO2S-RWD Substudy).

Reyes-Garcia R, Moreno-Pérez O, Guillen-Morote C, Modrego-Pardo I, Doulatram-Gamgaram VK, Casado Cases C, Arias Mendoza N, Tejera-Pérez C, Cárdenas-Salas J, Martínez-Fuster S, Lardiés-Sánchez B, Márquez-Pardo R, Pinés P, Tejera-Muñoz A, Fernández-García JC, On Behalf Of The Seen Diabetes Area.

Nutrients. 2025 Jul 17.17(14).

PMID: 40732973

FI: 5

http://dx.doi.org/10.3390/nu17142349This link opens in a popup window


Prevalence of reduced eGFR in European adults using KDIGO and age-adapted eGFR thresholds.

Astley ME, Chesnaye NC, Gambaro G, Ortiz A, Hallan S, Carrero JJ, Ebert N, Eriksen BO, Faucon AL, Ferraro PM, Ittermann T, Jonsson AJ, Langlo KAR, Melsom T, Schaeffner E, Stracke S, Palsson R, Jager KJ, Stel VS.

Nephrol Dial Transplant. 2025 Jul 17.

PMID: 40674065

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf112This link opens in a popup window


Loop diuretics in anuric hemodialysis patients for the clearance of protein-bound uremic toxins.

Sánchez-Ospina D, Romero-Cote M, Criado-Bellido L, Saez-Calero MI, Hijazi-Prieto B, Delgado-Cuesta S, Herrera-Gómez F, Mujika-Marticorena M, Gonzalez-Parra E, Izquierdo-Ortiz MJ, Mas-Fontao S.

Clin Kidney J. 2025 Jul.18(7):sfaf195.

PMID: 40671697

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf195This link opens in a popup window


Heterogeneity of regional and national hospitalization burden of lupus nephritis and systemic lupus erythematous.

Avello A, Fernández-Prado R, Abasheva D, Mahillo I, González-Gay MÁ, Martín-Cleary C, Arce-Obieta JM, Pérez-Gómez MV, Fernández-Fernández B, Ortiz A.

Clin Kidney J. 2025 Jul.18(7):sfaf162.

PMID: 40625697

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf162This link opens in a popup window


Immunoglobulin A/PIGR axis as potential mediators of human abdominal aortic aneurysms revealed by topologically resolved proteomics.

Cerro-Pardo I, Núñez E, Picatoste B, Márquez-Gálvez C, Ortega-Villanueva L, Raposo-Gutiérrez I, Lindholt JS, Blanco-Colio LM, Ramiro AR, Vázquez J, Martín-Ventura JL.

J Transl Med. 2025 Jul 07.23(1):747.

PMID: 40624587

FI: 7,5

http://dx.doi.org/10.1186/s12967-025-06758-yThis link opens in a popup window


Intensive Blood-Pressure Control in Patients with Type 2 Diabetes.

Fernandez-Fernandez B, Sarafidis P, Ortiz A.

N Engl J Med. 2025 Jul 03.393(1):96-97.

PMID: 40601948

FI: 78,5

http://dx.doi.org/10.1056/NEJMc2506053This link opens in a popup window


Global, regional, and national trends in routine childhood vaccination coverage from 1980 to 2023 with forecasts to 2030: a systematic analysis for the Global Burden of Disease Study 2023.

GBD 2023 Vaccine Coverage Collaborators(Ortiz A).

Lancet. 2025 Jul 19.406(10500):235-260.

PMID: 40578370

FI: 88,5

http://dx.doi.org/10.1016/S0140-6736(25)01037-2This link opens in a popup window


A call for urgent action on chronic kidney disease across Europe.

Ferro CJ, Wanner C, Luyckx V, Fontana M, Gallego D, Vanholder R, Torra R, Ortiz A, Stronger Kidneys Taskforce of the European Renal Association, the European Kidney Health Alliance and the European Kidney Patients Federation.

Lancet Reg Health Eur. 2025 Jul.54:101347.

PMID: 40548327

FI: 13

http://dx.doi.org/10.1016/j.lanepe.2025.101347This link opens in a popup window


Development of SOCS1 mimetics as novel approach to harmonize inflammation, oxidative stress, and fibrogenesis in metabolic dysfunction-associated steatotic liver disease.

Bernal S, Prieto I, Kavanagh M, Del Real IH, La Manna S, Lázaro I, Quiceno H, López-Sanz L, Picatoste B, Valdecantos MP, Mas-Fontao S, Sala-Vila A, Valverde ÁM, Marasco D, Egido J, Gómez-Guerrero C.

Redox Biol. 2025 Jul.84:103670.

PMID: 40373621

FI: 11,9

http://dx.doi.org/10.1016/j.redox.2025.103670This link opens in a popup window


Adult prognosis of childhood kidney replacement therapy: ERA Registry Figure of the Month.

Stel VS, Ortiz A, Kramer A.

Clin Kidney J. 2025 Jun.18(6):sfaf204.

PMID: 40625691

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf204This link opens in a popup window


Lorundrostat in Participants With Uncontrolled Hypertension and Treatment-Resistant Hypertension: The Launch-HTN Randomized Clinical Trial.

Saxena M, Laffin L, Borghi C, Fernandez Fernandez B, Ghali JK, Kopjar B, Polu K, Roger SD, Slingsby BT, Strutz F, Vogt L, Weir MR, Rodman D, Launch-HTN Investigators.

JAMA. 2025 Jun 30.

PMID: 40587141

FI: 55

http://dx.doi.org/10.1001/jama.2025.9413This link opens in a popup window


The Role of miR-802 in Diabetic Kidney Disease: Diagnostic and Therapeutic Insights.

Tejera-Muñoz A, Marchant V, Tejedor-Santamaría L, Opazo-Ríos L, Lavoz C, Gimeno-Longas MJ, Aceña JL, Ruiz-Ortega M, Rodrigues-Díez RR.

Int J Mol Sci. 2025 Jun 07.26(12).

PMID: 40564936

FI: 4,9

http://dx.doi.org/10.3390/ijms26125474This link opens in a popup window


Antioxidant Effects of SGLT2 Inhibitors on Cardiovascular-Kidney-Metabolic (CKM) Syndrome.

Guerrero-Mauvecin J, Villar-Gómez N, Miño-Izquierdo L, Povo-Retana A, Ramos AM, Ruiz-Hurtado G, Sanchez-Niño MD, Ortiz A, Sanz AB.

Antioxidants (Basel). 2025 Jun 09.14(6).

PMID: 40563333

FI: 6,6

http://dx.doi.org/10.3390/antiox14060701This link opens in a popup window


Preventing chronic kidney disease and maintaining kidney health: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Ortiz A, Arreola Guerra JM, Chan JCN, Jha V, Kramer H, Nicholas SB, Pavkov ME, Wanner C, Wong LP, Cheung M, King JM, Grams ME, Jadoul M, Tuttle KR, Conference Participants.

Kidney Int. 2025 Jun 18.

PMID: 40536455

FI: 12,6

http://dx.doi.org/10.1016/j.kint.2025.04.005This link opens in a popup window


Trends and Risk Factors of Pediatric Venous Thromboembolism in Spain: A Nationwide Study from 2016 to 2023.

Rueda-Camino JA, Sabrido-Bermúdez G, Barba-Martín R.

J Clin Med. 2025 Jun 03.14(11).

PMID: 40507718

FI: 2,9

http://dx.doi.org/10.3390/jcm14113950This link opens in a popup window


Chronic Kidney Disease of unexplained cause (CKDx): a consensus statement by the Genes & Kidney Working Group of the ERA.

Halbritter J, Figueres L, Van Eerde AM, Capasso G, Hoorn EJ, Nijenhuis T, Perez-Gomez MV, Sayer JA, Simons M, Walsh S, Zagorec N, Müller RU, Cornec-Le Gall E.

Nephrol Dial Transplant. 2025 Jun 03.

PMID: 40459916

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf092This link opens in a popup window


Towards early diagnosis of amyotrophic lateral sclerosis using near fibre EMG.

Garnés-Camarena O, Mahíllo-Fernández I, Martínez-Ulloa P, Mandeville R, Lorenzo O, Stashuk DW.

Clin Neurophysiol. 2025 Jun.174:114-122.

PMID: 40267619

FI: 3,6

http://dx.doi.org/10.1016/j.clinph.2025.04.006This link opens in a popup window


Global, regional and national burden of dietary iron deficiency from 1990 to 2021: a Global Burden of Disease study.

Lee S, Son Y, Hwang J, Kim MS, GBD 2021 Dietary Iron Deficiency Collaborators, Il Shin J, Yon DK, Kassebaum NJ (Ortiz A).

Nat Med. 2025 Jun.31(6):1809-1829.

PMID: 40263631

FI: 50

http://dx.doi.org/10.1038/s41591-025-03624-8This link opens in a popup window


Ultra-processed foods and cardio-kidney-metabolic syndrome: A review of recent evidence.

Kanbay M, Ozbek L, Guldan M, Abdel-Rahman SM, Narin AE, Ortiz A.

Eur J Intern Med. 2025 Jun.136:4-18.

PMID: 40122730

FI: 6,1

http://dx.doi.org/10.1016/j.ejim.2025.03.017This link opens in a popup window


Age- and sex-specific reference values of estimated glomerular filtration rate for European adults.

Astley ME, Chesnaye NC, Hallan S, Gambaro G, Ortiz A, Carrero JJ, Ebert N, Eriksen BO, Faucon AL, Ferraro PM, Indridason OS, Ittermann T, Jonsson AJ, Rise Langlo KA, Melsom T, Schaeffner E, Stracke S, Stel VS, Jager KJ.

Kidney Int. 2025 Jun.107(6):1076-1087.

PMID: 40122341

FI: 12,6

http://dx.doi.org/10.1016/j.kint.2025.02.025This link opens in a popup window


Dasatinib and Quercetin Combination Increased Kidney Damage in Acute Folic Acid-Induced Experimental Nephropathy.

Battaglia-Vieni A, Marchant V, Tejedor-Santamaria L, García-Caballero C, Flores-Salguero E, Ruiz-Torres MP, Rayego-Mateos S, Sanz AB, Ortiz A, Ruiz-Ortega M.

Pharmaceuticals (Basel). 2025 May 30.18(6).

PMID: 40573218

FI: 4,8

http://dx.doi.org/10.3390/ph18060822This link opens in a popup window


Nursing Students' Perceptions of Clinical Debriefing TALK©: A Qualitative Case Study.

González-Tejerina B, Pérez-Corrales J, Palacios-Ceña D, Abad-Valle J, Gómez PR, González-Toledo B, García-Carpintero Blas E, Garrigues-Ramón M.

Nurs Rep. 2025 May 30.15(6).

PMID: 40559485

FI: 2

http://dx.doi.org/10.3390/nursrep15060194This link opens in a popup window


A predictive model of non-diabetic kidney disease in patients with diabetes mellitus and chronic kidney disease. A Spanish multi-center study.

Bermejo S, González E, López-Revuelta K, Ibernon M, López D, Martín-Gómez A, Garcia-Osuna R, Linares T, Díaz M, Martín N, Barros X, Marco H, Navarro MI, Esparza N, Elias S, Coloma A, Roberto Robles N, Agraz I, Poch E, Rodas L, Lozano V, Fernández-Fernández B, Hernández E, Martínez MI, Stanescu RI, Moirón JP, García-Fernández N, Goicoechea M, Calero F, Bonet J, Liaño F, Pascual J, Praga M, Fulladosa X, Soler MJ.

Nefrologia (Engl Ed). 2025 May.45(5):360-368.

PMID: 40518653

FI: 2,6

http://dx.doi.org/10.1016/j.nefroe.2025.04.004This link opens in a popup window


Phthalate Metabolites and Their Relationship with Abdominal and General Obesity: Evidence from the Aragon Workers' Health Study (AWHS).

Akritidis J, Mérida DM, Torrijo-Belanche C, Moreno-Franco B, Gimeno-Ruiz S, Rey-García J, Morales-Suarez-Varela M, Guallar-Castillón P.

Nutrients. 2025 May 30.17(11).

PMID: 40507138

FI: 5

http://dx.doi.org/10.3390/nu17111869This link opens in a popup window


Defective Mitochondrial Respiration in Hereditary Thoracic Aneurysms.

Marcos-Ríos D, Rochano-Ortiz A, Méndez-Barbero N, Oller J.

Cells. 2025 May 23.14(11).

PMID: 40497944

FI: 5,2

http://dx.doi.org/10.3390/cells14110768This link opens in a popup window


Inherited kidney disease and CAKUT are common causes of kidney failure: ERA Registry Figure of the month.

Stel VS, Ortiz A, Kramer A.

Clin Kidney J. 2025 May.18(5):sfaf163.

PMID: 40453546

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf163This link opens in a popup window


Improvement in the detection, diagnosis, and early treatment of chronic kidney disease in Spain. The IntERKit project.

Górriz JL, Adán Gil F, Botana López MA, Buño Soto A, Campos Cabrera FJ, Cisneros A, Cobo Guerrero S, Conejos MD, Egocheaga Cabello I, Fernández Planelles MC, García-Matarín L, Jiménez N, Julián Mauro JC, León Jiménez D, Martínez Gamote D, Mazón Ramos P, Ortiz A, Palau G, Quevedo Rivera J, Sánchez-Álvarez JE, Tristancho Ajamil R, Varga Martín C, Vallés Fernández R.

Nefrologia (Engl Ed). 2025 May.45(5):351-359.

PMID: 40436675

FI: 2,6

http://dx.doi.org/10.1016/j.nefroe.2025.05.001This link opens in a popup window


Impact of albuminuria screening in primary care on the detection and management of chronic kidney disease: findings from the ONDAAS study.

Sánchez-Ospina D, Mas-Fontao S, Palencia MM, Prieto BH, Sánchez CG, Carcedo SP, Albo MR, Egido J, Ortiz A, Gonzalez-Parra E, Izquierdo Ortiz MJ, ONDAAS study investigators .

Clin Kidney J. 2025 May.18(5):sfaf123.

PMID: 40416393

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf123This link opens in a popup window


Prognostic value of extreme NT-proBNP levels in patients hospitalized for heart failure.

Yebra Yebra M, Sáenz de Urturi Rodríguez A, González García S, de Peralta García P, Asenjo Martínez M, Rueda Camino JA, Barba Martín R.

Med Clin (Barc). 2025 May 22.165(1):106990.

PMID: 40409228

FI: 2,1

http://dx.doi.org/10.1016/j.medcli.2025.106990This link opens in a popup window


siRNA-based therapeutics for lipoprotein (a) lowering: A path toward precision cardiovascular medicine.

Kanbay M, Ozbek L, Guldan M, Yilmaz ZY, Ortiz A, Mallamaci F, Zoccali C.

Eur J Clin Invest. 2025 May 23:e70079.

PMID: 40407123

FI: 3,6

http://dx.doi.org/10.1111/eci.70079This link opens in a popup window


Klotho plasma levels are an independent predictorof mortality in women with acute coronary syndrome.

Cortés M, Kallmeyer A, Tarín N, Cristóbal C, Pello AM, Aceña A, Gutiérrez-Landaluce C, Huelmos A, Alonso J, López-Bescós L, Mahíllo-Fernández I, Lorenzo Ó, González-Casaus ML, Egido J, Tuñón J.

Sci Rep. 2025 May 14.15(1):16744.

PMID: 40369094

FI: 3,9

http://dx.doi.org/10.1038/s41598-025-01334-2This link opens in a popup window


CCN2 Activates Cellular Senescence Leading to Kidney Fibrosis in Folic Acid-Induced Experimental Nephropathy.

Tejedor-Santamaria L, Marquez-Exposito L, Villacampa A, Marchant V, Battaglia-Vieni A, Rayego-Mateos S, Rodrigues-Diez RR, Santos FM, Valentijn FA, Knoppert SN, Broekhuizen R, Ruiz-Torres MP, Goldschmeding R, Ortiz A, Peiró C, Nguyen TQ, Ramos AM, Ruiz-Ortega M.

Int J Mol Sci. 2025 May 06.26(9).

PMID: 40362638

FI: 4,9

http://dx.doi.org/10.3390/ijms26094401This link opens in a popup window


Targeting IL-6 in antibody-mediated kidney transplant rejection.

Kanbay M, Mizrak B, Copur S, Alper EN, Akgul S, Ortiz A, Susal C.

Clin Kidney J. 2025 May.18(5):sfaf108.

PMID: 40357502

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf108This link opens in a popup window


Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019.

GBD 2019 Acute and Chronic Care Collaborators(Ortiz A).

Nat Commun. 2025 May 07.16(1):4235.

PMID: 40335470

FI: 15,7

http://dx.doi.org/10.1038/s41467-025-56910-xThis link opens in a popup window


Dietary vitamin D intake and 2-year changes in cognitive function in older adults with overweight or obesity and metabolic syndrome.

Vázquez-Lorente H, Ni J, Paz-Graniel I, Toledo E, Corella D, Castañer O, Martínez JA, Alonso-Gómez ÁM, Wärnberg J, Vioque J, Romaguera D, López-Miranda J, Estruch R, Tinahones FJ, Lapetra J, Serra-Majem L, Bouzalmate-Hajjaj A, Tur JA, Pérez RMM, Fanlo M, Delgado-Rodríguez M, Bustelo AB, Vidal J, Vázquez C, Daimiel L, Ros E, Fernández-Aranda F, Rognoni T, Babio N, Asensio EM, Pérez-Vega KA, Garcia-Rios A, Compañ-Gabucio L, Cueto-Galán R, Zulet MA, Nafria M, Casas R, Cano-Ibáñez N, Tojal-Sierra L, Gómez-Pérez AM, Goñi N, Sorli JV, Zomeño MD, Arenas-Larriva AP, Jiménez-Sellés P, Basterra-Gortari J, Fitó M, Salas-Salvadó J.

Geroscience. 2025 May 06.

PMID: 40325312

FI: 5,4

http://dx.doi.org/10.1007/s11357-025-01670-1This link opens in a popup window


CVOT summit report 2024: new cardiovascular, kidney, and metabolic outcomes.

Schnell O, Almandoz J, Anderson L, Barnard-Kelly K, Battelino T, Blüher M, Busetto L, Catrinou D, Ceriello A, Cos X, Danne T, Dayan CM, Del Prato S, Fernández-Fernández B, Fioretto P, Forst T, Gavin JR, Giorgino F, Groop PH, Harsch IA, Heerspink HJL, Heinemann L, Ibrahim M, Jadoul M, Jarvis S, Ji L, Kanumilli N, Kosiborod M, Landmesser U, Macieira S, Mankovsky B, Marx N, Mathieu C, McGowan B, Milenkovic T, Moser O, Müller-Wieland D, Papanas N, Patel DC, Pfeiffer AFH, Rahelić D, Rodbard HW, Rydén L, Schaeffner E, Spearman CW, Stirban A, Tacke F, Topsever P, Van Gaal L, Standl E.

Cardiovasc Diabetol. 2025 May 02.24(1):187.

PMID: 40316962

FI: 10,6

http://dx.doi.org/10.1186/s12933-025-02700-0This link opens in a popup window


Inkjet-Printed Graphene Multielectrode Arrays: An Accessible Platform for In Vitro Cardiac Electrophysiology.

Lumpuy-Castillo J, Fu Y, Avila Ramirez AE, Solodka K, Li J, Lorenzo O, Zeglio E, Garma LD.

ACS Appl Bio Mater. 2025 May 19.8(5):3708-3716.

PMID: 40285727

FI: 4,7

http://dx.doi.org/10.1021/acsabm.4c01677This link opens in a popup window


Increasing incidence of hypertensive disorders of pregnancy and association with decreased GFR and albuminuria: The need for post-partum follow-up.

Gracia-Iguacel C, Torán MP, Navidad MA, Pérez BG, Arce-Obieta JM, Morocho-Pindo C, González-Parra E, Mahillo I, Ortiz A.

Placenta. 2025 May 23.165:42-49.

PMID: 40203467

FI: 2,5

http://dx.doi.org/10.1016/j.placenta.2025.03.017This link opens in a popup window


A salty symphony: unraveling the tale of uromodulin and sodium sensitivity.

Karagiannidis AG, Theodorakopoulou MP, Iatridi F, Ortiz A, Sarafidis P.

J Hum Hypertens. 2025 May.39(5):320-333.

PMID: 40164702

FI: 3,4

http://dx.doi.org/10.1038/s41371-025-01013-9This link opens in a popup window


Role of Inflammatory and Proresolving Mediators in Endothelial Dysfunction.

Briones AM, Hernanz R, García-Redondo AB, Rodríguez C, Blanco-Colio LM, Val-Blasco A, Alonso MJ, Salaices M.

Basic Clin Pharmacol Toxicol. 2025 May.136(5):e70026.

PMID: 40159875

FI: 3,3

http://dx.doi.org/10.1111/bcpt.70026This link opens in a popup window


Aging-related hyperphosphatemia triggers the release of TNF-α from macrophages, promoting indicators of sarcopenia through the reduction of IL-15 expression in skeletal muscle.

Alcalde-Estévez E, Moreno-Piedra A, Asenjo-Bueno A, Martos-Elvira M, de la Serna-Soto M, Ruiz-Ortega M, Olmos G, López-Ongil S, Ruiz-Torres MP.

Life Sci. 2025 May 01.368:123507.

PMID: 40010633

FI: 5,1

http://dx.doi.org/10.1016/j.lfs.2025.123507This link opens in a popup window


Novel Truncating Variants in PODXL Represent a New Entity to Be Explored Among Podocytopathies.

García-Aznar JM, Besada-Cerecedo ML, Castro-Alonso C, Sierra Carpio M, Blasco M, Quiroga B, Červienka M, Mouzo R, Torra R, Ortiz A, de Sequera P.

Genes (Basel). 2025 Apr 18.16(4).

PMID: 40282423

FI: 2,8

http://dx.doi.org/10.3390/genes16040464This link opens in a popup window


Drivers and mechanisms of cognitive decline in chronic kidney disease.

Capasso G, Franssen CFM, Perna AF, Massy ZA, Menzies RI, Zoccali C, Tessitore A, Nedergaard M, Okusa MD, Ortiz A, Wagner CA, Unwin RJ.

Nat Rev Nephrol. 2025 Apr 25.

PMID: 40281076

FI: 39,8

http://dx.doi.org/10.1038/s41581-025-00963-0This link opens in a popup window


Mitochondrial Dysfunction: A New Hallmark in Hereditable Thoracic Aortic Aneurysm Development.

Marcos-Ríos D, Rochano-Ortiz A, San Sebastián-Jaraba I, Fernández-Gómez MJ, Méndez-Barbero N, Oller J.

Cells. 2025 Apr 21.14(8).

PMID: 40277943

FI: 5,2

http://dx.doi.org/10.3390/cells14080618This link opens in a popup window


ERA Registry Figure of the month Expected remaining years of life for dialysis and kidney transplant patients.

Stel VS, Ortiz A, Kramer A.

Clin Kidney J. 2025 Apr.18(4):sfaf091.

PMID: 40270644

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf091This link opens in a popup window


Impact of primary aldosteronism on calcium phosphate homeostasis. Results from the SPAIN-ALDO.

Iriarte-Durán MB, Paja Fano M, Rizo Gellida A, González-Boillos M, Parra Ramírez P, Martín Rojas-Marcos P, Caja L, García Cano AM, Ruiz-Sanchez JG, Vicente A, Gómez-Hoyos E, Recasens M, Barahona San Millan R, Picón César MJ, Díaz Guardiola P, Perdomo CM, Manjón-Miguélez L, Rebollo Román Á, Robles Lázaro C, Recio JM, Calatayud M, Jiménez López N, Sampedro Nuñez M, Mena Ribas E, Sanmartín Sánchez A, Gonzalvo Diaz C, Lamas C, Serrano J, Michalopoulou T, Tenes Rodrigo S, Jaén Aguila F, Moya Mateo EM, Gutiérrez-Medina S, Hanzu FA, Araujo-Castro M.

J Endocrinol Invest. 2025 Apr 19.

PMID: 40252188

FI: 3,5

http://dx.doi.org/10.1007/s40618-025-02563-yThis link opens in a popup window


Clinical Practice Guideline for detection and management of diabetic kidney disease: A consensus report by the Spanish Society of Nephrology.

Montero N, Oliveras L, Martínez-Castelao A, Gorriz JL, Soler MJ, Fernández-Fernández B, Quero M, García-Carro C, Garcia-Sancho P, Goicoechea M, Gorgojo Martínez JJ, Molina P, Puchades MJ, Rodríguez-Espinosa D, Sablón N, Santamaría R, Navarro-González JF, GEENDIAB (Spanish Diabetic Nephropathy Study Group).

Nefrologia (Engl Ed). 2025 Apr.45 Suppl 1:1-26.

PMID: 40222774

FI: 2,6

http://dx.doi.org/10.1016/j.nefroe.2025.04.005This link opens in a popup window


Maintaining kidney health in aging societies: a JSN and ERA call to action.

Ortiz A, Kramer A, Rychlík I, Nangaku M, Yanagita M, Jager KJ, Caskey FJ, Stel VS, Kashihara N, Kuragano T, Suzuki Y, Takemoto Y, Yokoi H, Palladino G, Fliser D, Torra R, Wanner C.

Nephrol Dial Transplant. 2025 Apr 10.

PMID: 40210592

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf068This link opens in a popup window


Transgender women and competitive sports: Considerations from Endocrinology.

Cuadrado Clemente L, Miguélez González M, Cabrera García P, Noval Font M, Alfaro Gandarillas É, Gómez Balaguer M, Palacios Gil de Antuñano N.

Endocrinol Diabetes Nutr (Engl Ed). 2025 Apr.72(4):101539.

PMID: 40185657

FI: 1,8

http://dx.doi.org/10.1016/j.endien.2025.101539This link opens in a popup window


Spanish Registry of Renal Patients: 2022 Report and evolutive analysis.

Quiroga B, Mahíllo B, Mazuecos A, Ortiz A, Farnés JC, Marrero DH, Alemán ST, de Pablos MCS, Arévalo OLR, Vidas MM, Slon-Roblero MF, Larrañaga MA, Eguren IM, Muñoz MOV, Camblor MR, Alia IM, Caamaño MEB, Galán MAB, Lorenzo JD, López HG, Monzon FEA, Marqués GG, Rodríguez-Benot A, Domínguez-Gil B, Álvarez ES, en nombre de todos los representantes del REER.

Nefrologia (Engl Ed). 2025 Apr.45(4):312-328.

PMID: 40175214

FI: 2,6

http://dx.doi.org/10.1016/j.nefroe.2025.03.002This link opens in a popup window


ERA Registry Figure of the month Trends in kidney transplantation rate across countries.

Stel VS, Ortiz A, Kramer A.

Clin Kidney J. 2025 Mar.18(3):sfaf055.

PMID: 40123965

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf055This link opens in a popup window


ABCDE to identify and prevent chronic kidney disease: a call to action.

Ferro CJ, Wanner C, Luyckx V, Stevens K, Cerqueira S, Darwish R, Fernandez Fernandez B, Fiel D, Filev R, Grieger M, Lopez A, Luman M, Malyszko J, Nikolova-Vlahova MK, Romero F, Skalioti C, Araújo CARDS, Ziedina I, Gallego D, Ortiz A, Torra R, Vanholder R.

Nephrol Dial Transplant. 2025 Mar 19.

PMID: 40107862

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf057This link opens in a popup window


Predictive factors of gait recovery after hip fracture: a scoping review.

González de Villaumbrosia C, Barba R, Ojeda-Thies C, Grifol-Clar E, Álvarez-Diaz N, Álvarez-Espejo T, Cancio-Trujillo JM, Mora-Fernández J, Pareja-Sierra T, Barrera-Crispín R, Calle-Egusquiza A, Capdevila-Reniu A, Carrasco-Paniagua C, Cervera Díaz MC, Condorhuamán-Alvarado P, Cotano-Abad L, Cuadra-Llopart L, García-Cárdenas V, González-Chávez S, Hernández-Sánchez LA, Herrero-Pinilla B, López-Castro J, Montero-Fernández N, Muñoz-Pascual A, Muñoz-Vélez M, Ortés-Gómez R, Sáenz-Tejada A, Sanz-Reig J, Torras-Cortada S, Ramos Cortés M, Sáez-López P.

Age Ageing. 2025 Mar 03.54(3).

PMID: 40100147

FI: 7,1

http://dx.doi.org/10.1093/ageing/afaf057This link opens in a popup window


Oxidative stress and inflammation on metabolic abnormalities and renal involvement in prediabetic subjects across Europe.

Mas-Fontao S, Civantos E, Boukichou-Abdelkader N, Soto-Catalan M, Romeo-Colas M, Marco A, Gomez-Guerrero C, Moreno JA, Tuomilehto J, Gabriel R, Egido J, ePREDICE investigators.

Nefrologia (Engl Ed). 2025 Mar.45(3):238-248.

PMID: 40082053

FI: 2,6

http://dx.doi.org/10.1016/j.nefroe.2025.02.009This link opens in a popup window


Cognitive impairment in chronic kidney disease: role of brain imaging, functional imaging, electroencephalography, cerebrospinal fluid biomarkers and sensors.

Andrade A, Bachmann M, Bobot M, Bruchfeld A, Fridolin I, Mani LY, Xu H, CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) collaborators (Ortiz A).

Nephrol Dial Transplant. 2025 Mar 13.40(Supplement_2):ii18-ii27.

PMID: 40080092

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfae256This link opens in a popup window


The role of the intestinal microbiome in cognitive decline in patients with kidney disease.

Wagner CA, Frey-Wagner I, Ortiz A, Unwin R, Liabeuf S, Suzumoto Y, Iervolino A, Stasi A, Di Marzo V, Gesualdo L, Massy ZA, CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) collaborators.

Nephrol Dial Transplant. 2025 Mar 13.40(Supplement_2):ii4-ii17.

PMID: 40080091

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfae253This link opens in a popup window


Cognitive impairment in kidney transplanted patients.

Malyszko J, Golenia A, Farisco M, Re VL, Klimkowicz-Mrowiec A, Capasso G, Goumenos D, Rroji M, Figurek A, Hafez G, CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) collaborators (Ortiz A).

Nephrol Dial Transplant. 2025 Mar 13.40(Supplement_2):ii46-ii53.

PMID: 40080090

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfae250This link opens in a popup window


Big databases and biobanks for studying the links between CKD, cognitive impairment, and dementia.

Zoccali C, Mallamaci F, Rosenberg K, Unwin R, Silva PI, Simeoni MA, Hafez G, Capasso G, Nitsch D, CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) collaborators (Ortiz A).

Nephrol Dial Transplant. 2025 Mar 13.40(Supplement_2):ii37-ii45.

PMID: 40080089

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfae255This link opens in a popup window


Chemotherapy-related cognitive impairment and kidney dysfunction.

Simeoni M, Mulholland MM, Workeneh BT, Capasso A, Hafez G, Liabeuf S, Malyszko J, Mani LY, Trevisani F, De A, Wagner CA, Massy ZA, Unwin R, Capasso G, CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) collaborators (Ortiz A).

Nephrol Dial Transplant. 2025 Mar 13.40(Supplement_2):ii54-ii63.

PMID: 40080088

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfae249This link opens in a popup window


CONNECT: what has been done and what needs to be done.

Capasso G, Unwin RJ, CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) collaborators (Ortiz A).

Nephrol Dial Transplant. 2025 Mar 13.40(Supplement_2):ii1-ii3.

PMID: 40080087

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfae248This link opens in a popup window


Care pathways for patients with cognitive impairment and chronic kidney disease.

Pépin M, Giannakou K, Levassort H, Farinha A, Bobot M, Lo Re V, Golenia A, Małyszko J, Mattace-Raso F, Klimkowcz-Mrowiec A, Garneata L, Vazelov E, Stepan E, Capolongo G, Massy Z, Wiecek A, CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) collaborators (Ortiz A).

Nephrol Dial Transplant. 2025 Mar 13.40(Supplement_2):ii28-ii36.

PMID: 40080086

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfae264This link opens in a popup window


Genetic and circulating biomarkers of cognitive dysfunction and dementia in CKD.

Zoccali C, Mallamaci F, Wagner CA, Unwin R, Nedergaard M, Hafez G, Malyszko J, Pepin M, Massy Z, Paolisso G, Remuzzi G, Capasso GB, CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) collaborators (Ortiz A).

Nephrol Dial Transplant. 2025 Mar 13.40(Supplement_2):ii64-ii75.

PMID: 40080085

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfae259This link opens in a popup window


Very low SBP targets and the boom-and-bust cycle of benefit and adverse kidney events.

Fernandez-Fernandez B, Valdivielso JM, Chinnappa S, Sarafidis P, Ortiz A.

Nephrol Dial Transplant. 2025 Mar 07.

PMID: 40053494

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf053This link opens in a popup window


Global, regional, and national prevalence of adult overweight and obesity, 1990-2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021.

GBD 2021 Adult BMI Collaborators(Ortiz A).

Lancet. 2025 Mar 08.405(10481):813-838.

PMID: 40049186

FI: 88,5

http://dx.doi.org/10.1016/S0140-6736(25)00355-1This link opens in a popup window


Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990-2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021.

GBD 2021 Adolescent BMI Collaborators (Ortiz A).

Lancet. 2025 Mar 08.405(10481):785-812.

PMID: 40049185

FI: 88,5

http://dx.doi.org/10.1016/S0140-6736(25)00397-6This link opens in a popup window


Recommendations of the Spanish Society of Endocrinology and Nutrition (SEEN) on ""what not to do"" in clinical practice.

Díez JJ, Anda E, Bretón I, González-Blanco C, Miguélez M, Zugasti A, Fernández A, Sociedad Española de Endocrinología y Nutrición.

Endocrinol Diabetes Nutr (Engl Ed). 2025 Mar.72(3):101531.

PMID: 40037943

FI: 1,8

http://dx.doi.org/10.1016/j.endien.2025.101531This link opens in a popup window


Towards a reduction of patients' refusal to perform arteriovenous fistula: New tools and new actors in the interdisciplinary vascular access team. Presentation of the ERCAV project.

Rosique López F, Luz Sánchez-Tocino M, Hernán Gascueña D, Santos-Ascarza Bacariza JL, Andúgar Rocamora L, Gallego Zurro D, Cabezuelo Romero JB, Prieto Velasco M, Martínez Losa A, Hadad-Arrascue F, Martínez Alarcón L, Manzano Sánchez D, Melero Rubio E, López Picasso M, Hernández A, Rubio Paez S, Roca-Tey R, Ibeas López J, Dolores Arenas M, Grupo de Trabajo Fundación Renal Grupo EspañolMutildisciplinar del Acceso Vascular (GEMAV), GTAVSEN (Grupo de Trabajo del AccesoVascular de la S.E.N.), Grupo de Trabajo de ERCA (Grupo de Trabajo de EnfermedadRenal Crónica Avanzada), Federación ALCER (Federación Nacional de Asociaciones parala lucha contra las enfermedades del riñón).

Nefrologia (Engl Ed). 2025 Mar.45(3):189-193.

PMID: 39986980

FI: 2,6

http://dx.doi.org/10.1016/j.nefroe.2025.02.006This link opens in a popup window


Diabetic foot infections in Internal Medicine services in Spain (2018-2022).

Fuentes Santos C, Rueda Camino JA, Asenjo Mota Á, Castaneda Pastor A, Zapatero Gaviria A, Canora Lebrato J, Barba-Martín R.

Rev Clin Esp (Barc). 2025 Mar.225(3):125-130.

PMID: 39864519

FI: 1,7

http://dx.doi.org/10.1016/j.rceng.2025.01.006This link opens in a popup window


Cognitive impairment in CKD patients: a guidance document by the CONNECT network.

Bolignano D, Simeoni M, Hafez G, Pepin M, Gallo A, Altieri M, Liabeuf S, Giannakou K, De A, Capasso G, CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) collaborators (Ortiz A).

Clin Kidney J. 2025 Feb.18(2):sfae294.

PMID: 40235626

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfae294This link opens in a popup window


ERA Registry Figure of the month Patient survival on dialysis and kidney transplantation.

Stel VS, Ortiz A, Kramer A.

Clin Kidney J. 2025 Feb.18(2):sfaf051.

PMID: 40040958

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf051This link opens in a popup window


Kidney expert consultation and the outcomes of in hospital acute kidney injury.

Saritas T, Cantaluppi V, Sanz Bartolome A, Faguer S, Gameiro J, Antonio Lopes J, Malyszko J, Ostermann M, Selby NM, De Seigneux S.

Nephrol Dial Transplant. 2025 Feb 28.

PMID: 40036875

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf043This link opens in a popup window


The ERA Registry Annual Report 2022: Epidemiology of Kidney Replacement Therapy in Europe, with a focus on sex comparisons.

Boenink R, Bonthuis M, Boerstra BA, Astley ME, Montez de Sousa IR, Helve J, Komissarov KS, Comas J, Radunovic D, Buchwinkler L, Hommel K, Gjorgjievski N, Galvão AA, Mitsides N, Vidas MM, Dębska-Ślizień AM, Ambrus C, Slon-Roblero MF, Ten Dam MAGJ, Lassalle M, Guidotti R, Marín Sánchez I, Kuzema V, Trujillo Alemán S, Ziginskiene E, Santhakumaran S, Valentin MO, Sarrión Auñón A, Indridason OS, Seyahi N, Artamendi Larrañaga M, Kravljaca M, Okša A, García López H, Åsberg A, Rychlik I, Ots-Rosenberg M, Beckerman P, Godanci-Kelmendi V, Stendahl M, Lakey J, Jager KJ, Ortiz A, Kramer A, Stel VS.

Clin Kidney J. 2025 Feb.18(2):sfae405.

PMID: 40008269

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfae405This link opens in a popup window


Psychobiotic Protection of Nutritional Supplements and Probiotics in Patients Undergoing Hemodialysis: A Randomized Trial.

Climent E, Hevilla F, Padial M, Barril-Cuadrado G, Blanca M, Jiménez-Salcedo T, López-Picasso M, Nogueira-Pérez Á, Olveira G.

Nutrients. 2025 Feb 12.17(4).

PMID: 40004979

FI: 5

http://dx.doi.org/10.3390/nu17040652This link opens in a popup window


Quality of life and clinical data in hemodialysis patients with different degrees of pruritus.

Fontao SM, Manso P, Audije-Gil J, Gascueña DH, Dapena F, Aresté N, Sánchez-Álvarez E, Molina P, Ojeda R, Goicoechea M, Simó VE, Bezhold GA, Prieto-Velasco M, Lloret MJ, Santos AB, Buades JM, Narváez C, Sánchez-Villanueva R, Pérez-Morales RE, Jiménez MDA, Fundación Renal Española Working Group, Prurito Working Group.

Sci Rep. 2025 Feb 20.15(1):6222.

PMID: 39979317

FI: 3,9

http://dx.doi.org/10.1038/s41598-024-83833-2This link opens in a popup window


Pasta Consumption and Cardiometabolic Risks in Older Adults with Overweight/Obesity: A Longitudinal Analysis.

Shyam S, Nishi SK, Ni J, Martínez-González MÁ, Corella D, Schröder H, Martínez JA, Alonso-Gómez ÁM, Wärnberg J, Vioque J, Romaguera D, López-Miranda J, Estruch R, Tinahones FJ, Lapetra J, Serra-Majem L, Bueno-Cavanillas A, Tur JA, Martín Sánchez V, Pintó X, Delgado-Rodríguez M, Matía-Martín P, Vidal J, Vázquez C, Daimiel L, Ros E, Gaforio JJ, Ruiz-Canela M, Fernández-Carrión R, Goday A, Garcia-Rios A, Torres-Collado L, Cueto-Galán R, Zulet MA, Prohens L, Casas R, Castillo-Hermoso MA, Tojal-Sierra L, Am GP, García-Arellano A, Sorlí JV, Castañer O, Arenas-Larriva AP, Oncina-Cánovas A, Goñi L, Fitó M, Babio N, Salas-Salvadó J.

J Am Nutr Assoc. 2025 Feb 19:1-13.

PMID: 39970054

FI: 2,6

http://dx.doi.org/10.1080/27697061.2025.2463454This link opens in a popup window


Access to kidney transplantation and re-transplantation from childhood to adulthood: long-term data from the ERA Registry.

Preka E, Bonthuis M, Marks SD, Kramer A, de Vries APJ, Sørensen SS, Bakkaloğlu SA, Bistrup C, Jahnukainen T, Arévalo OLR, Buchwinkler L, Segelmark M, Sanchez JE, Arnol M, Ordóñez-Álvarez FA, de la Cerda-Ojeda F, Plumb LA, Methven S, Palsson R, Lundgren T, Ríos H, Ortiz A, Stel VS, Harambat J, Jager KJ.

Nephrol Dial Transplant. 2025 Feb 12.

PMID: 39938931

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf025This link opens in a popup window


Lipid-lowering drug therapy for reducing cardiovascular risk in diabetes. A clinical view of the Cardiovascular Disease Working Group of the Spanish Diabetes Society.

Pedro-Botet J, Arrieta F, Botana M, Gimeno-Orna JA, Martínez-Montoro JI, Ortega-Martínez de Victoria E, Ribalta J, Sánchez-Margalet V, Pérez-Pérez A, Grupo de Trabajo de Enfermedad Cardiovascular de la Sociedad Española de Diabetes.

Endocrinol Diabetes Nutr (Engl Ed). 2025 Feb.72(2):101523.

PMID: 39924389

FI: 1,8

http://dx.doi.org/10.1016/j.endien.2025.101523This link opens in a popup window


Insights into the mechanisms of fibrosis and progressive kidney injury.

Lamas S, Ruiz-Ortega M.

Nat Rev Nephrol. 2025 Feb.21(2):79-80.

PMID: 39753691

FI: 39,8

http://dx.doi.org/10.1038/s41581-024-00922-1This link opens in a popup window


New Biomarkers in the Prognostic Assessment of Acute Heart Failure with Reduced Ejection Fraction: Beyond Natriuretic Peptides.

Cortés M, Lumpuy-Castillo J, García-Talavera CS, Arroyo Rivera MB, de Miguel L, Bollas AJ, Romero-Otero JM, Esteban Chapel JA, Taibo-Urquía M, Pello AM, González-Casaus ML, Mahíllo-Fernández I, Lorenzo O, Tuñón J.

Int J Mol Sci. 2025 Jan 24.26(3).

PMID: 39940753

FI: 4,9

http://dx.doi.org/10.3390/ijms26030986This link opens in a popup window


ERA Registry Figure of the month Time trends in dialysis incidence across age groups and countries.

Stel VS, Ortiz A, Kramer A.

Clin Kidney J. 2025 Jan.18(1):sfaf013.

PMID: 39896976

FI: 4,6

http://dx.doi.org/10.1093/ckj/sfaf013This link opens in a popup window


Cardiovascular risk assessment: Missing albuminuria contributing to gender inequality.

de Sequera P, Arias J, Quiroga B, Benavent M, Procaccini F, Romero I, López G, Diez J, Ortiz A.

Nefrologia (Engl Ed). 2025 Jan.45(1):87-93.

PMID: 39884803

FI: 2,6

http://dx.doi.org/10.1016/j.nefroe.2025.01.002This link opens in a popup window


Plasmid Gene Therapy for Monogenic Disorders: Challenges and Perspectives.

Luís MA, Goes MAD, Santos FM, Mesquita J, Tavares-Ratado P, Tomaz CT.

Pharmaceutics. 2025 Jan 14.17(1).

PMID: 39861752

FI: 5,5

http://dx.doi.org/10.3390/pharmaceutics17010104This link opens in a popup window


Nephrectomy in Autosomal Dominant Polycystic Kidney Disease: A consensus statement of the ERA Genes & Kidney Working Group.

Geertsema P, Gansevoort RT, Arici M, Capasso G, Cornec-Le-Gall E, Furlano M, Fuster DG, Galletti F, Gómez-Dos-Santos V, Perez-Gomez MV, Goumenos D, Halbritter J, Jambon E, Korst U, Leliveld AM, Felip MM, Figueiredo A, Nijenhuis T, Olsburgh J, Pol RA, Sayer JA, Stippel D, Torra R, Müller RU, Casteleijn NF, members of the study group.

Nephrol Dial Transplant. 2025 Jan 23.

PMID: 39848914

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf019This link opens in a popup window


Annexin A8 deficiency delays atherosclerosis progression.

Gutiérrez-Muñoz C, Blázquez-Serra R, San Sebastian-Jaraba I, Sanz-Andrea S, Fernández-Gómez MJ, Nuñez-Moreno G, Mínguez P, Escolá-Gil JC, Nogales P, Ollivier V, Martín-Ventura JL, Ho-Tin-Noe B, Rescher U, Méndez-Barbero N, Blanco-Colio LM.

Clin Transl Med. 2025 Jan.15(1):e70176.

PMID: 39835780

FI: 6,8

http://dx.doi.org/10.1002/ctm2.70176This link opens in a popup window


DEFENDER Trial: Dapagliflozin for Critically Ill Patients with Acute Organ Dysfunction -Implications for clinicians.

Malyszko J, De Seigneux S, Cantaluppi V, Faguer S, Gameiro J, Lopes JA, Sanz Bartolome A, Saritas T, Selby NM, Ostermann M.

Nephrol Dial Transplant. 2025 Jan 15.

PMID: 39814582

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf013This link opens in a popup window


Stratified medicine for blood pressure targets in type 2 diabetes mellitus.

Fernandez-Fernandez B, Valdivielso JM, Vogt L, Sarafidis P, Ortiz A.

Nephrol Dial Transplant. 2025 Jan 13.

PMID: 39805717

FI: 5,6

http://dx.doi.org/10.1093/ndt/gfaf007This link opens in a popup window


Trained immunity: from kidney failure to organ transplantation.

Ochando J, Ortiz A.

Nat Rev Nephrol. 2025 Jan 06.

PMID: 39762368

FI: 39,8

http://dx.doi.org/10.1038/s41581-024-00927-wThis link opens in a popup window

Projects, contracts and observational studies

PUBLIC

Sources of public funding for projects being developed at the IIS-FJD:

_FINANCIACIÓN-261007_FINANCIACIÓN-261007

REFERENCE

PROJECT TITLE

PRINCIPAL RESEARCHER

TYPE OF PROJECT

TOTAL FUNDING

CA21165

PERSONALIZED MEDICINE IN CHRONIC KIDNEY DISEASE: IMPROVED OUTCOME BASED ON BIG DATA (PERMEDIK)

AVELLO ESCRIBANO, ALEJANDRO

COLLABORATION NETWORKS. INTERNATIONAL

€0.00

AC22/00028

BODY FLUID PROTEOME SIGNATURES FOR PERSONALISED INTERVENTION TO PREVENT CARDIOVASCULAR AND RENAL COMPLICATIONS IN DIABETES

FERNANDEZ FERNANDEZ, BEATRIZ

CLINICAL RESEARCH PROJECTS. INTERNATIONAL

€148,830.00

AC22/00027

MULTI-MARKERS RISK ASSESSMENT OF KIDNEY SENSITIVITY TO INJURY TO PERSONALIZE PREVENTION OF ACUTE KIDNEY INJURY

ORTIZ ARDUAN, ALBERTO

CLINICAL RESEARCH PROJECTS. INTERNATIONAL

€173,030.00

KITNEWCARE (101137054)

KITNEWCARE. DEVELOPING A FRAMEWORK/MODEL TO ENVIRONMENTALLY SUSTAINABLE AND CLIMATE NEUTRAL HEALTH AND CARE SYSTEMS USING THE KIDNEY CARE PATHWAY

ORTIZ ARDUAN, ALBERTO

CLINICAL RESEARCH PROJECTS. INTERNATIONAL

€372,778.75

PREVENTCKD (101101220)

PREVENTCKD. ENHANCEMENT OF PREVENTION OF CHRONIC KIDNEY DISEASE IN THE EU: A TARGETED APPROACH TO TAKING ACTION

ORTIZ ARDUAN, ALBERTO

CLINICAL RESEARCH PROJECTS. INTERNATIONAL

€98,223.86

PICKED

PICKED: PERSONALIZED MEDICINE IN CHRONIC KIDNEY DISEASE

SANCHEZ NIÑO, DOLORES

CLINICAL RESEARCH PROJECTS. INTERNATIONAL

€251,971.20

CB16/11/00333

GRUPO DE INVESTIGACION DEL CIBER DE ENFERMEDADES CARDIOVASCULARES

BLANCO COLIO, LUIS MIGUEL

CIBER

€0.00

CB07/08/2007

GRUPO DE INVESTIGACION DEL CIBER DE DIABETES Y ENFERMEDADES METABÓLICAS ASOCIADAS (CIBERDEM)

EGIDO DE LOS RIOS, JESUS

CIBER

€0.00

PI22/00233

DESCIFRANDO EL PAPEL DE LAS ANEXINAS EN EL REMODELADO PATOLÓGICO DE LA PARED VASCULAR: BÚSQUEDA DE NUEVAS DIANAS DIAGNÓSTICAS Y/O TERAPÉUTICAS

BLANCO COLIO, LUIS MIGUEL

CLINICAL RESEARCH PROJECTS. ISCIII

€177,870.00

PI23/00119

EL PAPEL DE LA INFLAMACIÓN EN LA PREVENCIÓN DE LA DIABETES TIPO 2 Y SUS COMPLICACIONES. LA MODULACIÓN DE LAS VÍAS DE SEÑALIZACIÓN INFLAMATORIAS COMO TERAPIA AÑADIDA A LOS NUEVOS FÁRMACOS ANTIDIABÉTICOS.

EGIDO DE LOS RIOS, JESUS

CLINICAL RESEARCH PROJECTS. ISCIII

€252,500.00

PI23/00627

ADN LIBRE COMO BIOMARCADOR Y DIANA TERAPEUTICA EN ENFERMEDAD RENAL DIABÉTICA: DIFERENCIAS DE GÉNERO

FERNANDEZ FERNANDEZ, BEATRIZ

CLINICAL RESEARCH PROJECTS. ISCIII

€83,750.00

PI21/01430

PROFUNDIZACIÓN DEL ESTUDIO DEL IMPACTO DE LAS TOXINAS URÉMICAS AROMÁTICAS Y LOS BISFENOLES EN PACIENTES CON ENFERMEDAD RENAL CRÓNICA (ERC). PAPEL EN LA PROGRESIÓN Y ESTRATEGIAS CONTRA ESTE CÍRCULO VICIOSO

GONZALEZ PARRA, EMILIO JOSE

CLINICAL RESEARCH PROJECTS. ISCIII

€99,220.00

PI24/01630

MOVILIZANDO LAS TOXINAS URÉMICAS UNIDAS A PROTEÍNAS EN PACIENTES EN DIÁLISIS: HACIA UNA MEJORÍA EN LOS RESULTADOS CLÍNICOS

GONZALEZ PARRA, EMILIO JOSE

CLINICAL RESEARCH PROJECTS. ISCIII

€215,000.00

PI21/01126

NUEVOS MEDIADORES DE LA COMUNICACIÓN CELULAR ENDOTELIOMUSCULO LISO EN PATOLOGÍAS DE REMODELADO VASCULAR. ESTUDIO TRANSLACIONAL

MENDEZ BARBERO, NEREA

CLINICAL RESEARCH PROJECTS. ISCIII

€141,570.00

PI24/00180

DESCIFRANDO EL DIÁLOGO CELULAR EN LA PARED VASCULAR: CLAVE PARA LA BÚSQUEDA DE NUEVAS DIANAS DIAGNÓSTICAS Y/O TERAPÉUTICAS DEL REMODELADO VASCULAR PATOLÓGICO.

MENDEZ BARBERO, NEREA

CLINICAL RESEARCH PROJECTS. ISCIII

€152,500.00

ICI24/00034

TERAPIA CON CÉLULAS CAR-TCD19 EN NEFRITIS LÚPICA REFRACTARIA (CART-NEL)

ORTIZ ARDUAN, ALBERTO

CLINICAL RESEARCH PROJECTS. ISCIII

€1,401,180.00

PI22/00050

PROMOVIENDO LAS DEFENSAS ENDÓGENAS FRENTE A LA ENFERMEDAD RENAL

ORTIZ ARDUAN, ALBERTO

CLINICAL RESEARCH PROJECTS. ISCIII

€280,720.00

PMP21/00109

SPAIN CKD CAUSE (SPACKDC)

ORTIZ ARDUAN, ALBERTO

CLINICAL RESEARCH PROJECTS. ISCIII

€2,609,200.00

RD21/0005/0001

RED: RICORS2040 INFLAMACIÓN E INMUNOPATOLOGÍA DE ÓRGANOS Y SISTEMAS

ORTIZ ARDUAN, ALBERTO

COLLABORATION NETWORKS. ISCIII

€270,765.00

RD24/0004/0001

RICORS2040-RENAL

ORTIZ ARDUAN, ALBERTO

COLLABORATION NETWORKS. ISCIII

€389,983.00

PI22/01168

IDENTIFICACIÓN DE BIOMARCADORES DE RIESGO RENAL EN LA ENFERMEDAD DE ALPORT

PEREZ GOMEZ, MARIA VANESSA

CLINICAL RESEARCH PROJECTS. ISCIII

€81,070.00

PMP22/00119

RED NACIONAL DE LABORATORIOS DE FUNCIÓN RENAL

PEREZ GOMEZ, MARIA VANESSA

CLINICAL RESEARCH PROJECTS. ISCIII

€42,900.00

PI21/01453

FUNCIÓN MITOCONDRIAL E INFLAMACIÓN EN EL CURSO DEL FRACASO RENAL AGUDO. PAPEL DE PROTEÍNAS UNIDORAS DE ÁCIDOS GRASOS (FABP) Y DE DSBL- A EN NEFROPROTECCIÓN.

RAMOS CORTASSA, ADRIAN MARIO

CLINICAL RESEARCH PROJECTS. ISCIII

€147,620.00

PI24/00007

NUEVOS BIOMARCADORES Y DIANAS TERAPÉUTICAS EN LA COMUNICACIÓN GLOMERULAR CÉLULA-CÉLULA EN LA GLOMERULONEFRITIS CRESCENTE

RAYEGO MATEOS, SANDRA

CLINICAL RESEARCH PROJECTS. ISCIII

€171,250.00

PI23/00394

ENFERMEDAD RENAL CRÓNICA Y SENESCENCIA CELULAR: BUSCANDO LA CONEXIÓN PARA ENTENDER EL DAÑO RENAL Y EL ENVEJECIMIENTO

RUIZ ORTEGA, MARTA

CLINICAL RESEARCH PROJECTS. ISCIII

€277,500.00

RD21/0005/0002

RED: RICORS2040 INFLAMACIÓN E INMUNOPATOLOGÍA DE ÓRGANOS Y SISTEMAS

RUIZ ORTEGA, MARTA

COLLABORATION NETWORKS. ISCIII

€105,765.00

RD24/0004/0021

RICORS2040-RENAL

RUIZ ORTEGA, MARTA

COLLABORATION NETWORKS. ISCIII

€138,303.00

PI21/00251

CONSERVANDO LA EXPRESIÓN DE KLOTHO PARA RETRASAR EL ENVEJECIMIENTO RENAL

SANCHEZ NIÑO, DOLORES

CLINICAL RESEARCH PROJECTS. ISCIII

€244,420.00

PI24/00079

APROXIMACIONES TERAPÉUTICAS PARA RETRASAR EL ENVEJECIMIENTO RENAL ACELERADO

SANCHEZ NIÑO, DOLORES

CLINICAL RESEARCH PROJECTS. ISCIII

€227,500.00

PI22/00469

NUEVOS ABORDAJES DIAGNÓSTICOS Y TERAPÉUTICOS PARA PREVENIR LA MUERTE CELULAR E INFLAMACIÓN ACTIVADOS POR RIPK1 Y RIPK3 EN EL FRACASO RENAL AGUDO.

SANZ BARTOLOME, ANA BELEN

CLINICAL RESEARCH PROJECTS. ISCIII

€208,120.00

PID2021-127741OB-I00

REGULACIÓN DE INTERACCIONES MICRORNA-MRNA Y PROTEÍNA-PROTEÍNA EN DIABETES Y ENFERMEDADES METABÓLICAS ASOCIADAS: IMPLICACIONES PATOLÓGICAS Y TERAPÉUTICAS.

GOMEZ GUERRERO, CARMEN

INNOVATION PROJECTS. MINISTRY

€205,700.00

PID2022-136979OB-I00

MODULACIÓN DE LA GLICOSILACIÓN PARA PREVENIR EL REMODELADO VASCULAR PATOLÓGICO (GLYVASC)

MARTIN VENTURA, JOSE LUIS

CLINICAL RESEARCH PROJECTS. MINISTRY

€325,000.00

PID2022-137730OA-I00

NUEVAS DIANAS TERÁPEUTICAS METABÓLICAS EN AORTOPATÍAS

OLLER PEDROSA, JORGE

CLINICAL RESEARCH PROJECTS. MINISTRY

€193,750.00

S2022/BMD-7223

CONSORCIO PARA EL ESTUDIO DEL FRACASO RENAL Y SU IMPACTO EN LA PATOLOGIA CARDIOVASCULAR

ORTIZ ARDUAN, ALBERTO

CLINICAL RESEARCH PROJECTS. CAM

€75,440.00

FI20/00265

CONTRATO PFIS: RAFAEL BLÁZQUEZ SERRA

BLANCO COLIO, LUIS MIGUEL

PREDOCTORAL RESEARCH. ISCIII

€82,400.00

CP19/00151

IDENTIFICATION AND VALIDATION OF NEW TARGETS FOR THE DIAGNOSIS AND TREATMENT OF PATHOLOGICAL VASCULAR REMODELING OBTAINED BY RNA-SEQUENCING. ROLE OF ANXA8.

MENDEZ BARBERO, NEREA

POSTDOCTORAL. RESEARCH. ISCIII

€242,500.00

FI22/00140

CONTRATO PFIS: MARÍA JOSÉ FERNÁNDEZ GÓMEZ

MENDEZ BARBERO, NEREA

PREDOCTORAL RESEARCH. ISCIII

€119,567.00

FI23/00154

CONTRATO PFIS: CARLA MAYA LÓPEZ

PEREZ GOMEZ, MARIA VANESSA

PREDOCTORAL RESEARCH. ISCIII

€119,567.00

CP23/00025

CONTRATO MIGUEL SERVET: SANDRA RAYEGO MATEOS. NUEVO BIOMARCAORES Y OBJETIVOS TERAPÉURTICOS EN LA COMUNICACIÓN CELULAR EN ENFERMEDADES RENALES

RAYEGO MATEOS, SANDRA

POSTDOCTORAL. RESEARCH. ISCIII

€308,600.00

CD23/00049

CONTRATO SARA BORRELL: FÁTIMA RAQUEL MILHANO DOS SANTOS

RUIZ ORTEGA, MARTA

POSTDOCTORAL. RESEARCH. ISCIII

€95,000.00

RYC2021-033343-I

CONTRATO RYC: JORGE OLLER PEDROSA

OLLER PEDROSA, JORGE

POSTDOCTORAL. RESEARCH. MINISTRY

€236,350.00

FPU22/01519

CONTRATO FORMACIÓN PROFESORADO UNIVERSITARIO: NATALIA VILLAR GÓMEZ

SANZ BARTOLOME, ANA BELEN

PREDOCTORAL RESEARCH. MINISTRY

€81,800.74

RYC2019-026916-I

CONTRATO RYC: ANA BELÉN SANZ BARTOLOMÉ

SANZ BARTOLOME, ANA BELEN

POSTDOCTORAL. RESEARCH. MINISTRY

€308,600.00

PRIVATE

REFERENCE

PROJECT TITLE

PRINCIPAL RESEARCHER

TYPE OF PROJECT

5280/006

PAPEL DE LA ANEXINA A6 EN EL DESARROLLO, PROGRESIÓN Y CALCIFICACIÓN DE LA LESIÓN ATEROSCLERÓTICA.

BLANCO COLIO, LUIS MIGUEL

RESEARCH PROJECTS. COMPETITIVE

217310/001

ROLE OF IMMUNOGLOBULIN A DURING VASCULAR REMODELING AND METABOLIC DISEASE

MARTIN VENTURA, JOSE LUIS

RESEARCH PROJECTS. COMPETITIVE

HR22-00253

HARNESSING THE ADAPTIVE IMMUNE RESPONSE IN VASCULAR PATHOLOGIES: TOWARDS THE IDENTIFICATION OF NEW THERAPEUTIC AVENUES

MARTIN VENTURA, JOSE LUIS

RESEARCH PROJECTS. COMPETITIVE

232755/001

NUEVOS TRATAMIENTOS PARA EL SÍNDROME DE MARFAN.

OLLER PEDROSA, JORGE

RESEARCH PROJECTS. COMPETITIVE

232755/002

PAPEL DEL METABOLISMO EN EL SÍNDROME DE MARFAN (METAMARFAN)

OLLER PEDROSA, JORGE

RESEARCH PROJECTS. COMPETITIVE

08172/005

PRESERVING KLOTHO EXPRESSION TO DELAY KIDNEY AGING

SANCHEZ NIÑO, DOLORES

RESEARCH PROJECTS. COMPETITIVE

9749/006

IDENTIFICACIÓN Y CARACTERIZACIÓN DE NUEVOS MEDIADORES DE DAÑO RENAL DEPENDIENTES DE RIPK3

SANZ BARTOLOME, ANA BELEN

RESEARCH PROJECTS. COMPETITIVE

9749/007

UTILIDAD DE LA HUELLA MOLECULAR BASADA EN VESÍCULAS EXTRACELULARES CIRCULANTES PARA DETERMINAR LA AFECTACIÓN CARDIORRENAL EN PACIENTES CON DM2

SANZ BARTOLOME, ANA BELEN

RESEARCH PROJECTS. COMPETITIVE

7218107/003

ESTUDIO DEL EFECTO DE LA ADMINISTRACIÓN ORAL DE LPC-EPA EN UN MODELO MURINO DE ATEROSCLEROSIS

GOMEZ GUERRERO, CARMEN

RESEARCH PROJECTS

2024.075

SUPER"GAL-1 TREATMENT IN ATHEROSCLEROTIC PLAQUE REGRESSION AND/OR STABILIZATION

MARTIN VENTURA, JOSE LUIS

RESEARCH PROJECTS

4390/017

MEDICAL SCIENTIFIC ADVISORY BOARD AGREEMENT

ORTIZ ARDUAN, ALBERTO

RESEARCH PROJECTS

4390/025

TEGER – PROYECTO ESTRATÉGICO DE I+D (2024-2025-2026)

ORTIZ ARDUAN, ALBERTO

RESEARCH PROJECTS

9749/008

PRESTACIÓN DE SERVICIOS: DETERMINACIONES LABORATORIO CENTRAL PROYECTO UTILIDAD DEL PROTOCOLO VEXUS EN EL AJUSTE DE PESO IDEAL DE LOS PACIENTES EN HEMODIÁLISIS

SANZ BARTOLOME, ANA BELEN

RESEARCH PROJECTS

1547/001

DISPOSICIÓN DE UN DIETISTA EN EL SERVICIO DE NEFROLOGÍA DEL HOSPITAL GENERAL DE VILLALBA

SANCHEZ HERNANDEZ, ROSA

PERSONNEL/HUMAN RESOURCE

4390/016

HYPERKALEMIA IN ROUTINE CLINICAL PRACTICE: A RETROSPECTIVE COHORT STUDY AIMED TO SET UP A MONITORING TOOL OF THE INCIDENCE AND PREVALENCE OF HYPERKALEMIA IN 4 PUBLIC HOSPITALS IN MADRID DURING 1 YEAR-PERIOD, USING ELECTRONIC MEDICAL RECORDS

ORTIZ ARDUAN, ALBERTO

OBSERVATIONAL STUDIES

EOH053-24_FJD

ESTUDIO OBSERVACIONAL MULTICÉNTRICO PARA COMPARAR LAS RECOMENDACIONES DE MÉDICOS Y LAS DECISIONES DE AUTO-MEDICACIÓN DE PACIENTES EN EL USO DE TADALAFILO PARA EL TRATAMIENTO DE LA DISFUNCIÓN ERÉCTIL

ORTIZ ARDUAN, ALBERTO

OBSERVATIONAL STUDIES

EOH060-24_FJD

ESTUDIO POSAUTORIZACIÓN DE SEGURIDAD (EPAS) OBSERVACIONAL EN EUROPA PARA DETERMINAR Y CUANTIFICAR CON MÁS DETALLE EL PERFIL DE SEGURIDAD A LARGO PLAZO DEL USO DE LA VOCLOSPORINA RESPECTO A LA NEUROTOXICIDAD, LA NEFROTOXICIDAD CRÓNICA Y LAS NEOPLASIAS MALIGNAS

ORTIZ ARDUAN, ALBERTO

OBSERVATIONAL STUDIES

EOH077-21_FJD

PREVALENCIA DE FRAGILIDAD EN PACIENTES CON ENFERMEDAD RENAL CRÓNICA EN LISTA DE ESPERA DE TRASPLANTE RENAL EN ESPAÑA: UN ESTUDIO MULTICÉNTRICO

RAMOS VERDE, ANA MARIA

OBSERVATIONAL STUDIES

PIC022-25_FJD

EFECTOS DE LA SUPLEMENTACIÓN NUTRICIONAL ORAL ESPECIFICA (100% LACTOPROTEÍNA SÉRICA HIDROLIZADA Y ALTO APORTE DE MCT) EN PACIENTE ONCOLÓGICO SOMETIDO A RADIOTERAPIA, DESNUTRIDO O EN RIESGO DE DESNUTRICIÓN. ESTUDIO NORMA

DASSEN DE MONZO, MARIA CAROLINA

RESEARCH PROJECTS

PIC187-22_FJD

SEGUIMIENTO DE LAS VÍAS DE TRATAMIENTO EN PACIENTES ADULTOS CON HIPERPOTASIEMIA (TRACK). ESTUDIO LONGITUDINAL, PROSPECTIVO Y NO INTERVENCIONISTA DEL PROCESO DE TRATAMIENTO DE PACIENTES ADULTOS CON HIPERPOTASIEMIA

ORTIZ ARDUAN, ALBERTO

RESEARCH PROJECTS

PIC035-25_FJD

ESTUDIO PARA DETERMINAR LA PREVALENCIA Y LAS CARACTERÍSTICAS CLÍNICAS ASOCIADAS A LOS GRUPOS DE VARIANTES GENÉTICAS DE PKD1 EN LA POLIQUISTOSIS RENAL AUTOSÓMICA DOMINANTE (PQRAD)

PEREZ GOMEZ, MARIA VANESSA

RESEARCH PROJECTS

00400053

PRÁCTICAS FORMACIÓN EN CENTROS DE TRABAJO (FCT)

LORENZO GONZALEZ, OSCAR

TRAINING/TEACHING

00400052

FORMACIÓN PRÁCTICA DE ALUMNOS/AS DEL GRADO DE BIOMEDICINA Y BIOTECNOLOGÍA DE LA UNIVERSIDAD ALFONSO X EL SABIO

MENDEZ BARBERO, NEREA

TRAINING/TEACHING

00400066

HD SPOTLIGHT WEBINARS: BLOOD-INCOMPATIBILITY IN HAEMODIALYSIS: ALLEVIATING INFLAMMATION AND EFFECTS OF COAGULATION (OCTOBER 22ND, 2025)

ORTIZ ARDUAN, ALBERTO

TRAINING/TEACHING

2024.096

HIGH-VOLUME HEMODIAFILTRATION MEDICALSCIENTIFIC ADVISORY BOARD

ORTIZ ARDUAN, ALBERTO

TRAINING/TEACHING

00400054

PRÁCTICAS FORMACIÓN EN CENTROS DE TRABAJO (FCT)

PINTOR CHOCANO, ARANZAZU

TRAINING/TEACHING

00400062

JORNADA "TECH DAY": CENTRADA EN LAS TÉCNICAS DE SINGLE CELL Y SPATIAL TRANSCRIPTOMICS. CHARLA 10X (22 DE SEPTIEMBRE DE 2025)

SANZ BARTOLOME, ANA BELEN

TRAINING/TEACHING

00400042

I JORNADA DE ACTUALIZACIÓN EN MENOPAUSIA PARA ESPECIALISTAS EN ENDOCRINOLOGÍA Y NUTRICIÓN: LA MENOPAUSIA: ENCRUCIJADA HORMONO METABÓLICA (3 DE ABRIL DE 2025)

VAZQUEZ MARTINEZ, CLOTILDE

TRAINING/TEACHING


Clinical trials

The clinical trials listed below were in the recruitment phase in 2025. If you are interested in participating in any of the currently open trials, more information is available on the website (https://ensayos.quironsalud.es/)

EudraCT Number

TITLE

PHASE

MC1

INT2

PRINCIPAL RESEARCHER

2024-516095-15-00

A RANDOMISED, DOUBLE BLIND, PLACEBO-CONTROLLED, SINGLE ASCENDING DOSE, PHASE 1A/1B MULTI-CENTRE STUDY IN HEALTHY PARTICIPANTS AND PARTICIPANTS WITH AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF GSK4771261A

I

YES

YES

MARIA VANESSA PEREZ GOMEZ

2021-003037-11

ESTUDIO EN FASE II, DE GRUPOS PARALELOS, DOBLE CIEGO Y CON TRES GRUPOS DE TRATAMIENTO, PARA EVALUAR LA EFICACIA Y LA SEGURIDAD DE FINERENONA MÁS EMPAGLIFLOZINA EN COMPARACIÓN CON FINERENONA O EMPAGLIFLOZINA EN PARTICIPANTES CON ENFERMEDAD RENAL CRÓNICA Y DIABETES TIPO 2.

II

YES

YES

ALBERTO ORTIZ ARDUAN

2023-505755-40-00

(22040 ALPINE 1) A PHASE 2B DOSE-FINDING, RANDOMIZED, PLACEBOCONTROLLED, DOUBLE-BLIND STUDY TO EVALUATE EFFICACY AND SAFETY OF BAY 3283142 ON TOP OF STANDARD OF CARE IN REDUCING ALBUMINURIA IN PATIENTS WITH CHRONIC KIDNEY DISEASE

II

YES

YES

ALBERTO ORTIZ ARDUAN

2024-510846-15-00

EFFICACY, SAFETY, AND PHARMACOKINETICS OF NNC0519-0130 ONCE WEEKLY S.C. VERSUS SEMAGLUTIDE 1.0 MG AND PLACEBO IN PEOPLE WITH CHRONIC KIDNEY DISEASE, WITH OR WITHOUT TYPE 2 DIABETES, AND WITH OVERWEIGHT OR OBESITY: A PROOF-OF-CONCEPT AND DOSE-FINDING STUDY

II

YES

YES

ALBERTO ORTIZ ARDUAN

2024-511775-15-00

ESTUDIO PARA EVALUAR LA EFICACIA Y LA SEGURIDAD DE FREXALIMAB, SAR442970 O RILZABRUTINIB EN PARTICIPANTES DE 16 A 75 AÑOS CON GLOMERULOESCLEROSIS FOCAL SEGMENTARIA PRIMARIA O ENFERMEDAD DE CAMBIOS MÍNIMOS

II

YES

YES

ALBERTO ORTIZ ARDUAN

2023-506511-17-00

ENSAYO PILOTO DOBLE CIEGO CONTROLADO CON PLACEBO, DE BP1.4979 PARA EL TRATAMIENTO DE LA HIPERFAGIA BULÍMICA

II

YES

YES

CLOTILDE VAZQUEZ MARTINEZ

2024-520322-11-00

ESTUDIO EN FASE II, ALEATORIZADO, CONTROLADO CON PLACEBO CON ENMASCARAMIENTO DOBLE Y CON COMPARADOR ACTIVO EN ABIERTO, DE GRUPOS PARALELOS Y MULTICÉNTRICO PARA EVALUAR LA EFICACIA, LA SEGURIDAD Y LA TOLERABILIDAD DE RO7795081 ADMINISTRADO UNA VEZ AL DÍA DURANTE 30 SEMANAS A PARTICIPANTES CON DIABETES MELLITUS DE TIPO 2

II

YES

YES

CLOTILDE VAZQUEZ MARTINEZ

2023-505292-73-00

A PHASE 2A, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO
EVALUATE THE SAFETY AND TOLERABILITY, PHARMACOKINETICS, PHARMACODYNAMICS, AND PRELIMINARY EFFICACY OF THE NOX1/4 INHIBITOR SETANAXIB IN PATIENTS WITH ALPORT SYNDROME

II

YES

YES

MARIA VANESSA PEREZ GOMEZ

2023-509638-20-00

VONAFEXOR FIXED DOSE-ESCALATION SAFETY AND PROOF-OF-CONCEPT STUDY IN PATIENTS WITH AT RISK OF PROGRESSION ALPORT SYNDROME

II

YES

YES

MARIA VANESSA PEREZ GOMEZ

2024-517143-31-00

ESTUDIO EN FASE II, MULTICÉNTRICO, ALEATORIZADO, DOBLE CIEGO Y CONTROLADO CON PLACEBO PARA EVALUAR LA SEGURIDAD Y LA EFICACIA
DE ABBV-CLS-628 EN PACIENTES ADULTOS CON POLIQUISTOSIS RENAL AUTOSÓMICA DOMINANTE (PQRAD)

II

YES

YES

MARIA VANESSA PEREZ GOMEZ

2022-500273-14-00

ESTUDIO EN FASE IIB/III, MULTICÉNTRICO, ALEATORIZADO, DOBLE CIEGO, CONTROLADO CON PLACEBO, COMBINADO DE BÚSQUEDA DE DOSIS Y RESULTADOS CARDIOVASCULARES PARA INVESTIGAR LA EFICACIA Y LA SEGURIDAD DE CSL300 (CLAZAKIZUMAB) EN PACIENTES CON NEFROPATÍA TERMINAL SOMETIDOS A DIÁLISIS

II/III

YES

YES

ALBERTO ORTIZ ARDUAN

2023-503772-24-00

A PHASE 2B/3, MULTI-PART, RANDOMIZED, DOUBLE-BLINDED, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ATACICEPT IN SUBJECTS WITH IGA NEPHROPATHY (IGAN)

II/III

YES

NO

ALBERTO ORTIZ ARDUAN

2017-004605-41

ESTUDIO ALEATORIZADO, MULTICÉNTRICO, DOBLE CIEGO, DE GRUPOS PARALELOS Y CONTROLADO CON PRINCIPIO ACTIVO, DE LA EFICACIA Y LA SEGURIDAD DE ESPARSENTÁN PARA EL TRATAMIENTO DE LA NEFROPATÍA POR INMUNOGLOBULINA A

III

YES

YES

ALBERTO ORTIZ ARDUAN

2021-004174-64

ESTUDIO PIVOTAL DE FASE III MULTICÉNTRICO, ALEATORIZADO, DOBLE CIEGO Y COMPARADO CON PLACEBO SOBRE LA EFICACIA Y LA SEGURIDAD DE DMX-200 EN PACIENTES CON GLOMERULOESCLEROSIS FOCAL Y SEGMENTARIA (GEFS) QUE ESTÉN EN TRATAMIENTO CON UN ANTAGONISTA DE LOS RECEPTORES DE LA ANGIOTENSINA II (ARA-II)

III

YES

YES

ALBERTO ORTIZ ARDUAN

2022-501802-36-00

ARTEMIS RAVULIZUMAB PARA PROTEGER A LOS PACIENTES CON INSUFICIENCIA RENAL CRÓNICA (IRC) DE SUFRIR UNA LESIÓN RENAL AGUDA ASOCIADA A LA INTERVENCIÓN QUIRÚRGICA CARDÍACA (CSA-AKI) Y ACONTECIMIENTOS RENALES ADVERSOS GRAVES (ARAG) POSTERIORES: ESTUDIO DE FASE III, MULTICÉNTRICO, ALEATORIZADO, DOBLE CIEGO Y CONTROLADO CON PLACEBO

III

YES

YES

ALBERTO ORTIZ ARDUAN

2023-506425-12-00

MLS-101-301: A RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED, PARALLEL ARM, MULTICENTER PHASE 3 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF LORUNDROSTAT IN SUBJECTS WITH UNCONTROLLED AND RESISTANT HYPERTENSION

III

YES

YES

ALBERTO ORTIZ ARDUAN

2023-506457-38-00

A PHASE III, RANDOMISED, DOUBLE -BLIND, ACTIVE-CONTROLLED STUDY TO ASSESS THE EFFICACY, SAFETY AND TOLERABILITY OF BAXDROSTAT IN COMBINATION WITH DAPAGLIFLOZIN COMPARED WITH DAPAGLIFLOZIN ALONE ON CHRONIC KIDNEY DISEASE (CKD) PROGRESSION IN PARTICIPANTS WITH CKD AND HIGH BLOOD PRESSURE

III

YES

YES

ALBERTO ORTIZ ARDUAN

2024-514135-17-00

A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF POVETACICEPT IN ADULTS WITH IMMUNOGLOBULIN A NEPHROPATHY (RAINIER)

III

YES

YES

ALBERTO ORTIZ ARDUAN

2024-519345-30-00

ESTUDIO DE FASE 3, ALEATORIZADO, DOBLE CIEGO Y CONTROLADO CON PLACEBO SOBRE EL FELZARTAMAB EN ADULTOS CON NEFROPATÍA POR IGA (PREVAIL)

III

YES

YES

ALBERTO ORTIZ ARDUAN

2019-004183-21

UN ESTUDIO PARA EVALUAR LA EFICACIA Y SEGURIDAD DE XYLOCORE, UNA SOLUCIÓN EXPERIMENTAL AHORRADORA DE GLUCOSA, PARA DIÁLISIS PERITONEAL

III

YES

YES

CATALINA MARTIN CLEARY

2022-500817-14-00

ESTUDIO DE FASE 3, ALEATORIZADO, DOBLE CIEGO, COMPARATIVO CON UN PLACEBO, PARA INVESTIGAR EL EFECTO DE TIRZEPATIDA SOBRE LA REDUCCIÓN DE LA MORBIMORTALIDAD EN ADULTOS CON OBESIDAD

III

YES

YES

CLOTILDE VAZQUEZ MARTINEZ

2021-003062-12

A PHASE 3 STUDY OF THE EFFICACY AND SAFETY OF LIXIVAPTAN IN PARTICIPANTS WITH AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE CONSISTING OF A 1-YEAR DOUBLE-BLIND, PLACEBO-CONTROLLED, RANDOMIZED PHASE AND A 1-YEAR OPEN-LABEL PHASE: THE ACTION STUDY.

III

YES

YES

MARIA VANESSA PEREZ GOMEZ

2022-500210-26-00

HYDROCHLOROTHIAZIDE TO PROTECT POLYCYSTIC KIDNEY DISEASE PATIENTS AND IMPROVE THEIR QUALITY OF LIFE (HYDRO-PROTECT)

III

YES

YES

MARIA VANESSA PEREZ GOMEZ

2023-505868-11-00

EFFICACY OF COLCHICINE IN SECONDARY PREVENTION OF VASCULAR EVENTS AND RENAL PROGRESSION IN PATIENTS WITH MODERATE CHRONIC RENAL DISEASE (COLCHIREN STUDY)

III

YES

NO

MARIA VANESSA PEREZ GOMEZ

NA

ANÁLISIS DE NECESIDADES PSICOSOCIALES EN PACIENTES CON ENFERMEDAD RENAL CRÓNICA E INTERVENCIÓN PSICOLÓGICA BASADA EN LA TERAPIA DE ACEPTACIÓN Y COMPROMISO (ACT) (ENSAYO CLÍNICO ALEATORIZADO).

NA

YES

NO

EMILIO JOSE GONZALEZ PARRA

NA

ESTUDIO ALEATORIZADO, CRUZADO, PARA COMPARAR LAS MODIFICACIONES DEL BPA SÉRICO DE 3 MEMBRANAS PARA HEMODIÁLISIS

NA

YES

NO

EMILIO JOSE GONZALEZ PARRA

NA

ESTUDIO DEL IMPACTO DE LA COMBINACIÓN DE LA MICRONUTRICIÓN BÁSICA Y LA ALIMENTACIÓN BAJA EN PROTEÍNAS EN LA MEJORA DE LA INSUFICIENCIA RENAL CRÓNICA DE GRADO IIIA, IIIB O IV

NA

YES

NO

MIGUEL AGANZO YEVES

NA

ENSAYO ALEATORIZADO DE NO INFERIORIDAD PARA EVALUAR UN CONSEJO DE CONSUMO MODERADO DE ALCOHOL FRENTE A UN CONSEJO DE ABSTENCIÓN

NA

YES

YES

ROSA SANCHEZ HERNANDEZ

MC1: MULTICENTRE INT2: INTERNATIONAL





Patents (revisar)

Title: Composición farmacéutica y su uso para la fabricación de un medicamento para el tratamiento de la enfermedad renal crónica y método de selección de compuestos.

Application No: P201430081

Main entities: FIIS-FJD (80%), IdiPaz (20%)

Inventors: Alberto Ortiz Arduán, Mª Dolores Sánchez Niño.


Title: Péptido derivado de SOCS1 para su uso en complicaciones crónicas de la diabetes.

Application No: P201430796

Main entities: VHIR (49%), IIS-FJD (26%), UAM (25%)

Inventors: Jesús Egido de los Ríos; Carmen Gómez Guerrero.


Title: SOCS1-derived peptide for use in chronic complications relating to diabetes.

Application No: PCT/ES2015/070415

Main entities: VHIR (49%), IIS-FJD (26%), UAM (25%)

Inventors: Jesús Egido de los Ríos; Carmen Gómez Guerrero; Rafael Simó Canonge; Cristina Hernández Pascual.


Title: Uso de la pentoxifilina y de una composición farmacéutica para elaborar un medicamento para prevenir el envejecimiento prematuro en humanos.

Application No: P201530616

Main entities: IIS-FJD (75%), Hospital Universitario Nuestra Sa. De Candelaria (25%)

Inventors: Alberto Ortiz Arduán, Dolores Sánchez Niño, Ana Belén Sanz Bartolomé, Juan Francisco Navarro González.


Title: Uso de una composicion farmaceutica para la fabricacion de un medicamento para el tratamiento y/o la prevencion del dano renal agudo.

Application No: P201531328

Main entities: FIIS-FJD (90%), CBMSO (10%)

Inventors: Alberto Ortiz Arduán, Dolores Sánchez Niño, Manuel Fresno.


Title: Derivados del crotonato para la fabricación de un medicamento para el tratamiento de enfermedad renal crónica y fracaso renal agudo.

Application No: P201531677

Main entities: FIIS-FJD (100%)

Inventors: Alberto Ortiz Arduán, Dolores Sánchez Niño, Ana Belén Sanz Bartolomé, Olga Ruiza Andrés.


Title: Elaboración de un medicamento para prevenir el envejecimiento prematuro en humanos, composición farmacéutica y método de selección de compuestos basado en el uso de siRNA de NFKbiz.

Application No: P201531933

Main entities: FIIS-FJD (100%)

Inventors: Alberto Ortiz Arduán, Dolores Sánchez Niño, Ana Belén Sanz Bartolomé, Jonay Poveda.


Title: Composición farmacéutica que comprende un vector en el que se ha clonado el gen de BCL3, uso de la misma y vector.

Application No: P201631183

Main entities: FIIS-FJD (100%)

Inventors: Alberto Ortiz Arduán, Dolores Sánchez Niño, Ana Belén Sanz Bartolomé, Jonay Poveda.


Title: GDF15 en orina como biomarcador de daño renal.

Application No: P201830849

Main entities: FIIS-FJD (100%)

Inventors: Alberto Ortiz Arduán, Dolores Sánchez Niño, Ana Belén Sanz Bartolomé, María Vanessa Pérez Gomez, Beatriz Fernández Fernández.


Title: In vitro method for detecting renal disease.

Application No: EP19382470.3

Main entities: FIIS-FJD (60%); UAM (40%)

Inventors: D. Alberto Ortiz Arduán, Emilio Gonzalez-Parra, Jesus Egido de los Ríos, Marta Ruiz-Ortega, Sandra Rayego-Mateos, José Luis Morgado Pascual.


Title: SOCS1 derived peptides for use in the treatment of liver diseases.

Application No: EP22383040.7

Main entities: FIIS-FJD (74%), UAM (26%)

Inventors: Jesus Egido De Los Ríos, Carmen Gómez Guerrero, Sebastián Mas Fontao, Manuel Soto Catalán, Daniela Marasco, Sara La Manna, Susana Bernal Uribe, Lucas Opazo Ríos, Ignacio Prieto Arroyo, Laura López Sanz, Luna Jiménez Castilla.


Title: SOCS1 derived peptides for use in the treatment of liver diseases.

Application No: PCT/EP2023/079934

Main entities: FIIS-FJD (74%), UAM (26%)

Inventors: Jesus Egido De Los Ríos, Carmen Gómez Guerrero, Sebastián Mas Fontao, Manuel Soto Catalán, Daniela Marasco, Sara La Manna, Susana Bernal Uribe, Lucas Opazo Ríos, Ignacio Prieto Arroyo, Laura López Sanz, Luna Jiménez Castilla.


Title: HBS - method for the diagnosis of aneurysm, and inhibitors for use in the prevention or treatment of aneurysm.

Application No: EP23383195.7

Main entities: FIIS-FJD (50%), CSIC (50%)

Inventors: María Mittelbrum, Jorge Oller Pedrosa.


Registros de Propiedad Intelectual

Title: MAKIPS-Calculadora FRA-H.
Código identificativo: 059cdd34360ef63525302ccea3b33e00f2f89ffb1b916f0f81adb0df26c41c34
Centro: HUFJD
Autor/es: Alberto Ortiz Arduan.