Medical and Surgical Innovation Associated Group
Data update as of 31/12/2025

2025 DATA
Leaders
|
PI
Research
LocationDepartment of Anaesthesiology, Critical Care and Pain Medicine, 3rd floor Fundación Jiménez Díaz University Hospital. Avda. Reyes Católicos, 2. 28040 Madrid (Spain). KeywordsTechnology, organisational innovation, automation, surgical management, complexity, efficiency, surgical scheduling, and organisational models. |
Gender perspective

Summary of activities
The group focuses on the application of technology to the study of advanced life support in patients with severe multiorgan diseases and on the development of new mechanical ventilation strategies. Research activities also include the analysis of acute haemorrhage using thromboelastographyy, to reduce bleeding and to minimise the use of blood product transfusions. In addition, the group has incorporated ultrasound into both intraoperative and immediate postoperative patient care to assess haemodynamic instability and facilitate prompt diagnosis, enabling the rapid implementation of appropriate therapeutic interventions.
Contributions to society
All scientific activities conducted by the Medical and Surgical Innovation group are directly aimed at improving patient outcomes and generating benefits for society.
Collaborations
The Medical and Surgical Innovation group collaborates closely with the New Therapies Research group through the incorporation of computer-assisted analysis for the treatment of facial deformities and for the diagnosis and management of dysphagia. The group also contributes to the development of prognostic tools for chronic hepatitis, acute lung injury and acute kidney injury associated with sepsis.
PhD Theses

List of publications
Palliative care training in Spanish Emergency Services: identifying needs and opportunities - a cross-sectional study.
Lobo-Antuña M, Lobo-Antuña V, Paredes-Coronel C, García-Romo E.
Eur J Emerg Med. 2026 Feb 01.33(1):54-56.
PMID: 41459602
FI: 4,2
http://dx.doi.org/10.1097/MEJ.0000000000001283
Bone mineral density and trabecular bone score in Spanish postmenopausal osteoporosis-free women: correlation with demographic factors.
M Diaz-Curiel, JL Neyro, M Andrade-Poveda, I Mahillo-Fernandez.
Rev Osteoporosis Metab Miner. 2025;17(2):84-89.
PMID: 10.20960/RevOsteoporosMetabMiner.00073
FI: 0,5
http://dx.doi.org/10.20960/RevOsteoporosMetabMiner.00073
Overview of the multidisciplinary team activity in patients with hepatocellular carcinoma and their survival outcomes.
Guarini V, Garzòn C, Casado D, Casanova M, Villarejo P, Azinovic I, Crespo E, Fernandez I, Lopez M, de Bourio MM, Moran M, Jimenez M, Medrano G, Castellano V, Lamarca A.
ESMO Gastrointest Oncol. 2025 Dec.10 (2025): 100263.
PMID: 10.1016/j.esmogo.2025.100263
FI: 0
http://dx.doi.org/10.1016/j.esmogo.2025.100263
Experimental determination of effective X-ray attenuation coefficients of 3D-printed materials under clinical mammography spectra.
Belarra A, Hernández-Girón I, Garayoa J, Martínez LC, Valverde J, Rot MJ, Ferrando A, Martín A, Chevalier M.
Front Bioeng Biotechnol. 2025.13:1719551.
PMID: 41725985
FI: 4,8
http://dx.doi.org/10.3389/fbioe.2025.1719551
Acute gluten-induced inflammatory response highlights CCL20 as a potential biomarker for celiac disease.
Gómez-Aguililla S, Farrais S, López-Palacios N, Arau B, Senosiain C, Infante-Menéndez J, Ruiz-Carnicer Á, Fernández-Bañares F, González-López N, Pujals M, Sousa C, Núñez C.
Front Immunol. 2025.16:1745890.
PMID: 41601633
FI: 5,9
http://dx.doi.org/10.3389/fimmu.2025.1745890
Hepatocellular carcinoma in non-cirrhotic liver: a prospective Spanish multicenter study.
Romero Gutiérrez M, Pascual S, Gómez-Rubio M, Aracil C, Márquez L, Piqueras B, Bernal-Monterde V, Ferrer T, Miquel M, Fernández C, González-Santiago JM, Horta D, Alarcón C, Martín A, Latorre R, Gutiérrez ML, Rendón P, Blanco-Sampascual S, Testillano M, Hernández-Guerra M, Tejedor M, Delgado C, Matilla A, Gómez Rodríguez R.
Rev Esp Enferm Dig. 2025 Dec 18.
PMID: 41410255
FI: 4
http://dx.doi.org/10.17235/reed.2025.11674/2025
Machine learning-based treatment outcome prediction in head and neck cancer using integrated noninvasive diagnostics.
Yeghaian M, Trebeschi S, Herrero-Huertas M, Ferradás FJM, Bos P, van Alphen MJA, van Gerven MAJ, Beets-Tan RGH, Bodalal Z, van der Velden LA.
Int J Comput Assist Radiol Surg. 2025 Dec 08.
PMID: 41359226
FI: 2,3
http://dx.doi.org/10.1007/s11548-025-03539-2
OBE-DIGITHUM: A Clinician-Led Digital Pathway for Sustainable Obesity Care-A Perspective.
Montoya T, Cárdenas JJ, Luca BL, Paniagua A, García-Valdecasas L, Reigosa L, Cruz S, Mas-Fontao S, Sierra R, Pérez de Arenaza V, Aganzo M, Gómez-Meana Á, Izquierdo I, Vázquez C.
Obes Rev. 2025 Dec 02:e70042.
PMID: 41330569
FI: 7,4
http://dx.doi.org/10.1111/obr.70042
Uses and technique of ultrasound-guided botulinum toxin infiltration.
Llorente Peris J, Miranda Bautista J, Menéndez Fernández-Miranda P.
Radiologia (Engl Ed). 2025.67(6):501695.
PMID: 41224378
FI: 1,1
http://dx.doi.org/10.1016/j.rxeng.2025.501695
Exploratory integration of near-infrared spectroscopy with clinical data: a machine learning approach for HCV detection in serum samples.
Pérez-Gómez E, Gómez J, Gonzalo J, Salgüero S, Riado D, Casas ML, Gutiérrez ML, Jaime E, Pérez-Martínez E, García-Carretero R, Ramos J, Fernández-Rodríguez C, Catalá M, Martino L, Barquero-Pérez Ó.
Front Med (Lausanne). 2025.12:1596476.
PMID: 40552174
FI: 3
http://dx.doi.org/10.3389/fmed.2025.1596476
Ultrasound-guided postmortem biopsies in the ICU: diagnostic yield and future applications beyond the pandemic.
Vidal González Á, Páez Vargas JJ, Robaglia D, Vicente Montaña AM, Fortes Alen JR, Prieto Pérez L.
Med Intensiva (Engl Ed). 2025 Nov 26:502362.
PMID: 41309369
FI: 3,1
http://dx.doi.org/10.1016/j.medine.2025.502362
Predicting Outcome and Duration of Mechanical Ventilation in Acute Hypoxemic Respiratory Failure: The PREMIER Study.
Villar J, González-Martín JM, Fernández C, Soler JA, Rey-Abalo M, Mora-Ordóñez JM, Ortiz-Díaz-Miguel R, Fernández L, Murcia I, Robaglia D, Añón JM, Ferrando C, Parrilla D, Dominguez-Berrot AM, Cobeta P, Martínez D, Amaro-Harpigny A, Andaluz-Ojeda D, Fernández MM, Gómez-Bentolila E, Steyerberg EW, Camporota L, Szakmany T.
J Clin Med. 2025 Nov 07.14(22).
PMID: 41302939
FI: 2,9
http://dx.doi.org/10.3390/jcm14227903
Economic burden of eosinophilic esophagitis in the first year after diagnosis in Spain: A direct medical cost analysis.
Rodriguez-Alcolado L, Aranda-Reneo I, Casabona S, Pérez-Martínez I, Guagnozzi D, Gutiérrez-Junquera C, Amorena E, Guardiola-Arévalo A, de la Peña-Negro L, Jhon LB, García-Dionisio SL, Fernández-Pacheco J, Barrio J, Fernández-Fernández S, Betoré E, de la Riva S, Teruel Sánchez-Vegazo C, Rodríguez-Oballe JA, Naves JE, Bisso-Zein JK, Carrión S, Suárez A, Llerena-Castro R, García-Díaz A, Nantes-Castillejo Ó, Granja-Navacerrada A, Perelló A, Álvarez-García M, Santander C, Laserna-Mendieta EJ, Oliva-Moreno J, Lucendo AJ.
Eur J Health Econ. 2025 Nov 18.
PMID: 41252104
FI: 3
http://dx.doi.org/10.1007/s10198-025-01872-6
Evaluation of adherence to the gluten-free diet in adolescent and adult patients with coeliac disease: a strategy based on the determination of gluten immunogenic peptides endorsed by the Spanish Society of Coeliac Disease (SEEC).
Pizarro Moreno Á, Garzón Benavides M, Comino I, Donat E, Farrais Villalba S, Fernández Salazar L, Molero M, Montoro Huguet M, Ribes-Koninckx C, Santolaria S, Simón E, Sousa C, Vivas S, Núñez C.
Rev Esp Enferm Dig. 2025 Nov 17.
PMID: 41247357
FI: 4
http://dx.doi.org/10.17235/reed.2025.11519/2025
Postmortem ultrastructural lung and liver injury in a critically ill COVID-19 patient.
González ÁV, Montaña AM, Piris MC, Prieto-Pérez L.
BMJ Case Rep. 2025 Nov 12.18(11).
PMID: 41224683
FI: 0,5
http://dx.doi.org/10.1136/bcr-2025-267289
When magnetic resonance imagin shows what sodium doesn't: Beyond osmotic imbalance in central pontine myelinolysis.
Maqueda Lluva D, Garrido Callén A, Pérez Torres M.
Med Intensiva (Engl Ed). 2025 Nov 07:502297.
PMID: 41206340
FI: 3,1
http://dx.doi.org/10.1016/j.medine.2025.502297
Design and implementation of a lomustine circuit as a safe practice.
Barreras Ruiz N, Ortega Menendez P, Jiménez Navarro L, Blanco Saiz E, Bonilla Porras M, Bécares Martinez J.
J Oncol Pharm Pract. 2025 Nov 06:10781552251393175.
PMID: 41197234
FI: 0,9
http://dx.doi.org/10.1177/10781552251393175
Maternal experience in the intensive care unit and post-discharge care: the third report from the MaCriCare study.
Cantellow S, Balcerzak Ł, Schyns-van den Berg A, Dabrowska D, Guasch E, Jörnvall H, Lucas N, Mercier FJ, Weiniger CF, Krawczyk P, MaCriCare Study Group.
Int J Obstet Anesth. 2025 Nov.64:104737.
PMID: 40782693
FI: 2,3
http://dx.doi.org/10.1016/j.ijoa.2025.104737
Effects of an Electronic Patient Reported Outcome Measures (e-PROMs) Program on Symptom Reporting, Use of Healthcare, and Overall Survival in Patients With Lymphoma: A Multicenter Prospective Study.
Córdoba R, Del Olmo Rodríguez M, Ramos S, López García A, Morillo D, Pérez-Sáenz MA, Miranda C, Martos R, Beltrán L, Castillo E, Herrero A, Gómez-Meana A, Pfang B, Short Apellaniz J, Arcos-Campillo J.
EJHaem. 2025 Oct.6(5):e70129.
PMID: 40909396
FI: 1,2
http://dx.doi.org/10.1002/jha2.70129
Differences in histopathologic features and diagnostic performance of 99mTc-methoxy-isobutyl-isonitrol single photon emission tomography-CT and 18F-fluorocholine positron emission tomography-CT in primary hyperparathyroidism.
Osorio-Silla I, González DM, Quiceno Arias HD, Peinado PP, Cárdenas Salas JJ, González MM, Pestana Soares CA, Martínez Ruiz LF, Landaeta Kancev LC, Dhier LM, Escanciano M, Sánchez de Molina ML, Ruíz AP, Campos PV.
Surgery. 2025 Oct.186:109595.
PMID: 40782725
FI: 2,7
http://dx.doi.org/10.1016/j.surg.2025.109595
Analgesic Effect of a Novel Intravenous Ibuprofen-Low-Dose Tramadol Combination: A Multimodal Approach to Moderate-to-Severe Postoperative Dental Pain.
Salas-Butrón MR, Laredo-Velasco L, Rivas-Paterna AB, González-Corchon A, Muñoz-Guerra MF, Borobia AM, Acero-Sanz JJ, Pérez-Ingidua C, Abad-Santos F, Cebrián JL, Gálvez-Múgica MÁ, Serrano-García I, Portolés-Díez C, Llanos L, Martínez D, Sanz N, Calandria C, Vargas-Castrillón E, Martín-Granizo R, Portolés-Pérez A.
Pharmaceutics. 2025 Sep 24.17(10).
PMID: 41155885
FI: 5,5
http://dx.doi.org/10.3390/pharmaceutics17101248
The World Federation Societies of Anaesthesiologists' (WFSA) declaration on patients' right to labour analgesia: raising awareness and elevating the role of anaesthesiologists in global maternal health.
Guasch E, George RB.
Int J Obstet Anesth. 2025 Sep 29.65:104784.
PMID: 41061387
FI: 2,3
http://dx.doi.org/10.1016/j.ijoa.2025.104784
Diagnostic value and clinical implications of 75SeHCAT scan in bile acid diarrhea.
Riado Mínguez D, Fernández-Gordón FM, Casado Portolés M, Gómez Labrador C, Cuadrado Tiemblo C, Suárez Cabredo CG, Wong Becerra LW, Castaño Milla C.
Gastroenterol Hepatol. 2025 Sep 24:502584.
PMID: 41005651
FI: 1,9
http://dx.doi.org/10.1016/j.gastrohep.2025.502584
More than step counts: Slow walking speed, limited running, and fewer long walks predict cardiovascular mortality in the Walk Watch UK Biobank study.
Herrero Pinilla B, Hong S, Brodie MA, Lord SR, Chan LLY.
J Gerontol A Biol Sci Med Sci. 2025 Sep 19.80(10).
PMID: 40845147
FI: 3,8
http://dx.doi.org/10.1093/gerona/glaf184
Shocking evidence to diminish fibrosis after lipedema reductive surgery.
Reyes Valdivia A, Chuquisana C.
Phlebology. 2025 Aug 10:2683555251369082.
PMID: 40785137
FI: 1,5
http://dx.doi.org/10.1177/02683555251369082
Environmental sustainability in intensive care: An international survey of intensive care professionals'views, practices and proposals to the European Society of Intensive Care Medicine.
Iliopoulou K, Leone M, Hunfeld N, Ferrer R, Baid H, Ostermann M, Scaramuzzo G, Touw H, Ioan AM, Theodorakopoulou M, Francois G, De Waele JJ.
J Crit Care. 2025 Aug.88:155079.
PMID: 40267551
FI: 2,9
http://dx.doi.org/10.1016/j.jcrc.2025.155079
ESAIC Mellin-Olsen declaration on diversity, equity and inclusion.
Gisselbaek M, Saxena S, Berger-Estilita J, Ateleanu B, Brazzi L, Buhre W, Crisan I, Camilleri-Podesta AM, Coburn M, Durnev V, Filipescu D, Ghezel-Ahmadi D, Golubovska I, Arévalo EG, Honorato-Cia C, Klimek M, Meco BC, Myatra SN, Nahtomi-Shick O, Neskovic V, O'Sullivan E, Rubulotta F, Romero C, Sabelnikovs O, Struys MM, Südy R, Weynants C, Ringvold EM, Matot I.
Eur J Anaesthesiol. 2025 Jul 01.42(7):579-583.
PMID: 40314611
FI: 6,8
http://dx.doi.org/10.1097/EJA.0000000000002186
Effects of a nationwide teledermatology program on access to care for skin cancer and premalignant lesions in public and private health care: A retrospective case-control analysis of data from eight Spanish hospitals.
Toledo-Pastrana T, Mora D, Martin-Gutierrez F, Fernández Valdés-Martín C, Corrales-Rodriguez A, Pfang B, Villegas García MA, Alcaraz-Leon I, Vicente J, Short Apellániz J, Blanco Rubio A, Herrero A, Del Olmo M, Álvaro de la Parra JA.
J Am Acad Dermatol. 2025 Jul.93(1):281-283.
PMID: 40120816
FI: 11,8
http://dx.doi.org/10.1016/j.jaad.2025.03.037
A Data-Centric Approach to Deep Learning for Brain Metastasis Analysis at MRI.
Topff L, Petrychenko L, Jain N, Lingier S, Bertels J, Astudillo P, Prosec M, Menéndez Fernández-Miranda P, Gevaert O, Smits M, Derks S, Verhaak E, Hanssens PEJ, Marco de Lucas E, Sutil R, Dominguez PD, Negoita A, Visser E, Corral Fontecha D, Braun LMM, Brandsma D, Visser JJ, Ranschaert ER, Groot Lipman KBW, Beets-Tan RGH.
Radiology. 2025 Jun.315(3):e242416.
PMID: 40552999
FI: 15,2
http://dx.doi.org/10.1148/radiol.242416
Guidelines on strategies for the universal implementation of videolaryngoscopy.
Gómez-Ríos MÁ, Van Zundert AAJ, McNarry AF, Law JA, Higgs A, De Jong A, Jaber S, Karamchandani K, Hansel J, Saracoglu KT, Leach R, Guimaraes HP, Abad-Gurumeta A, Gómez-Ríos D, Michalek P, Berkow LC, Fernández-Vaquero MÁ, Serrano-Moraza A, Gaitini L, Vaida S, Somri M, Gaszyński T, Brewster D, Desai N, Saracoglu A, Tsan SEH, Athanassoglou V, Komasawa N, Garg R, Shamim F, Rajendram R, Gutierrez-Couto U, López T, De Luis-Cabezón N, Flores DT, Garzón JC, Sastre JA, Roca de Togores López A, Meléndez-Salinas D, Fandiño-Orgeira JM, Casans-Frances R, Casalderrey-Rivas M, Romero-García E, Marín-Zaldívar C, Aroca-Tanarro A, Alonso-Correa O, Rodríguez-Martín LJ, Espinosa-Ramírez S, Hagberg CA.
Eur J Anaesthesiol. 2025 Jun 19.
PMID: 40534455
FI: 6,8
http://dx.doi.org/10.1097/EJA.0000000000002210
Anaesthetic strategies for managing placenta accreta spectrum with REBOA: Insights from an international multicentre retrospective study.
Azem K, Orbach-Zinger S, Ioscovich A, Brogly N, Spiegel E, Shoham A, Shatalin D, Valbuena I, Frenkel A, Isasi LMV, Matatov Y, Fein S, Greenman D, Neeman Y, Guasch E, Binyamin Y.
Eur J Anaesthesiol. 2025 Jun 06.
PMID: 40474704
FI: 6,8
http://dx.doi.org/10.1097/EJA.0000000000002218
Dermatologists' perception of teledermatology and risk factors for burnout: A cross-sectional study.
Toledo Pastrana T, Paredes Coronel C, Martín Gutiérrez FJ, Fernández-Martín Valdés C, Corrales Rodríguez A, Aspe Unanue L, Casulleras González A, Alcántara Reifs C, Bota Llorca A, Ortega Berbel L, Dios Guillan V, Short Apellaniz J, Del Olmo Rodriguez M, Pfang B, DermaON Quirónsalud Teledermatology Response Group.
J Eur Acad Dermatol Venereol. 2025 May 07.
PMID: 40331887
FI: 8
http://dx.doi.org/10.1111/jdv.20715
Revisiting artifact spread function evaluation in digital breast tomosynthesis systems.
Ovejero JG, Alarcia M, Barba JC, Cabañero B, Cuesta JA, García-Sanz A, Megías JM, Garayoa J, Chevalier M.
Phys Med. 2025 May.133:104982.
PMID: 40279988
FI: 2,7
http://dx.doi.org/10.1016/j.ejmp.2025.104982
Effectiveness and safety of rectal tacrolimus in patients with ulcerative colitis. TACRO-TOPIC study of GETECCU.
Fuentes-Valenzuela E, Bastón-Rey I, García-Alonso FJ, Elosua A, Zabalza San Martín L, Leo Carnerero E, Garcia de la Filia I, Pedraza Pérez A, Sáiz Chumillas RM, Pascual Oliver A, Muñoz Villafranca C, Moreno V, Suárez Ferrer C, Molina G, Ferreiro-Iglesias R, Vega Villaamil P, Gardeazábal Mateos D, Segarra-Ortega JX, Garrido Marín A, Doallo AI, Alonso-Galán H, Brunet-Mas E, Jimenez García N, López Romero-Salazar F, Velayos B, Carballo-Folgoso L, Pérez Santamaría C, Mata Román L, Núñez Ortiz A, Barrio J, Barreiro-de Acosta M, Gutiérrez-Casbas A.
J Crohns Colitis. 2025 May 08.19(5).
PMID: 40205922
FI: 8,7
http://dx.doi.org/10.1093/ecco-jcc/jjaf058
Towards a practice of neuraxial blocks under real-time ultrasound guidance: from preprocedural screening to direct guidance.
Brogly N, Guasch E.
Minerva Anestesiol. 2025 May.91(5):370-372.
PMID: 40047524
FI: 2,8
http://dx.doi.org/10.23736/S0375-9393.25.18903-7
Iron deficiency and anemia in pregnancy: a call to action!: -""If you don't take a temperature, you can't find a fever"".
Kranke P, Weiniger CF, Sultan P, Achebe MO, Filipescu D, Brogly N, Surbek D, Lasocki S, Guasch E, Meybohm P.
Int J Obstet Anesth. 2025 May.62:104298.
PMID: 39987638
FI: 2,3
http://dx.doi.org/10.1016/j.ijoa.2024.104298
Effects of Virtually Led Value-Based Preoperative Assessment on Safety, Efficiency, and Patient and Professional Satisfaction.
Martínez JLG, Coca MÁM, Del Olmo Rodríguez M, Vigoa P, Gómez JM, Apellaniz JS, Coronel CP, García MAV, Serrano JJ, Arcos J, Caramés Sánchez C, Pfang B, Álvaro de la Parra JA.
J Clin Med. 2025 Apr 29.14(9).
PMID: 40364124
FI: 2,9
http://dx.doi.org/10.3390/jcm14093093
Prevalence and evolution of newly diagnosed autoimmune gastritis in a large Spanish retrospective cohort.
Fuentes-Valenzuela E, Escribano Cruz S, Parra Villanueva J, Calvache Rodríguez A, Gil Díaz A, López-Martín MDC, Rubio de la Plaza I, Blanco S, Chivato Martín-Falquina I, Rodríguez-Batllori Aran B, Latorre Martinez R, Castillo Herrera LA, Olvera R, Alcalde Rodríguez D, Guzmán López K, Bejerano Domínguez A.
Rev Esp Enferm Dig. 2025 Apr 25.
PMID: 40276987
FI: 4
http://dx.doi.org/10.17235/reed.2025.11101/2025
Management of postoperative pain after cesarean section: advances in ultrasound-guided regional blocks.
Brogly N, Guasch E.
Minerva Anestesiol. 2025 Apr 23.
PMID: 40265501
FI: 2,8
http://dx.doi.org/10.23736/S0375-9393.25.19016-0
Elucidating Immune Cell Changes in Celiac Disease: Revealing New Insights from Spectral Flow Cytometry.
Gómez-Aguililla S, Farrais S, Senosiain C, López-Palacios N, Arau B, Ruiz-Carnicer Á, Sánchez-Domínguez R, Corzo M, Casado I, Pujals M, Bodas A, Sousa C, Núñez C.
Int J Mol Sci. 2025 Mar 21.26(7).
PMID: 40243487
FI: 4,9
http://dx.doi.org/10.3390/ijms26072877
Follow-up in coeliac disease: evidence and future challenges.
Castañeda Agredo A, Farrais Villalba S, Sanders DS.
Rev Esp Enferm Dig. 2025 Mar 27.
PMID: 40145902
FI: 4
http://dx.doi.org/10.17235/reed.2025.11168/2025
Diagnosis of celiac disease on a gluten-free diet: a multicenter prospective quasi-experimental clinical study.
Gómez-Aguililla S, Farrais S, López-Palacios N, Arau B, Senosiain C, Corzo M, Fernandez-Jimenez N, Ruiz-Carnicer Á, Fernández-Bañares F, González-García BP, Tristán E, Montero-Calle A, Garranzo-Asensio M, Casado I, Pujals M, Hernández JM, Infante-Menéndez J, Roy G, Sousa C, Núñez C.
BMC Med. 2025 Mar 26.23(1):182.
PMID: 40140887
FI: 8,3
http://dx.doi.org/10.1186/s12916-025-04008-y
Predictive factors of gait recovery after hip fracture: a scoping review.
González de Villaumbrosia C, Barba R, Ojeda-Thies C, Grifol-Clar E, Álvarez-Diaz N, Álvarez-Espejo T, Cancio-Trujillo JM, Mora-Fernández J, Pareja-Sierra T, Barrera-Crispín R, Calle-Egusquiza A, Capdevila-Reniu A, Carrasco-Paniagua C, Cervera Díaz MC, Condorhuamán-Alvarado P, Cotano-Abad L, Cuadra-Llopart L, García-Cárdenas V, González-Chávez S, Hernández-Sánchez LA, Herrero-Pinilla B, López-Castro J, Montero-Fernández N, Muñoz-Pascual A, Muñoz-Vélez M, Ortés-Gómez R, Sáenz-Tejada A, Sanz-Reig J, Torras-Cortada S, Ramos Cortés M, Sáez-López P.
Age Ageing. 2025 Mar 03.54(3).
PMID: 40100147
FI: 7,1
http://dx.doi.org/10.1093/ageing/afaf057
Early Prediction of ICU Mortality in Patients with Acute Hypoxemic Respiratory Failure Using Machine Learning: The MEMORIAL Study.
Villar J, González-Martín JM, Fernández C, Añón JM, Ferrando C, Mora-Ordoñez JM, Martínez D, Mosteiro F, Ambrós A, Fernández L, Murcia I, Vidal A, Pestaña D, Romera MA, Montiel R, Domínguez-Berrot AM, Soler JA, Gómez-Bentolila E, Steyerberg EW, Szakmany T.
J Clin Med. 2025 Mar 04.14(5).
PMID: 40095813
FI: 2,9
http://dx.doi.org/10.3390/jcm14051711
ESAIC focused guidelines for the management of the failing epidural during labour epidural analgesia.
Brogly N, Valbuena Gómez I, Afshari A, Ekelund K, Kranke P, Weiniger CF, Lucas N, Dewandre PY, Guasch Arevalo E, Ioscovich A, Kollmann A, Lindelof K, Orbach-Zinger S, Reis S, van den Bosch O, Van de Velde M, Romero CS.
Eur J Anaesthesiol. 2025 Feb 01.42(2):96-112.
PMID: 39744744
FI: 6,8
http://dx.doi.org/10.1097/EJA.0000000000002108
Capítulo 22 La gestión del servicio de medicina nuclear.
Martinez Dhier L.
. ISBN-9788490525562-22.
PMID: ISBN-9788490525562-22
FI: 0
http://dx.doi.org/ISBN-9788490525562-22
To considerate perforation of duodenal diverticula.
Álvarez-García M, Milán Pilo MV, Otegui L, Calvo Hernández R, Polo B, Bosch Esteva O.
Rev Esp Enferm Dig. 2025 Jan 09.
PMID: 39784684
FI: 4
http://dx.doi.org/10.17235/reed.2024.10955/2024
Implementing a closed loop clinical decision support system for sustainable preoperative care.
Gracia Martínez JL, Pfang B, Morales Coca MÁ, Caramés Sánchez C, Del Olmo Rodríguez M, Villegas García MA, Short Apellaniz J, Arcos Campillo J, Álvaro de la Parra JA, Manzano Lorefice F, Muñoz Alameda LE.
NPJ Digit Med. 2025 Jan 03.8(1):6.
PMID: 39753745
FI: 15,1
http://dx.doi.org/10.1038/s41746-024-01371-7
Projects, contracts and observational studies
PUBLIC
Sources of public funding for projects being developed at the IIS-FJD:
:

|
REFERENCE |
PROJECT TITLE |
PRINCIPAL RESEARCHER |
TYPE OF PROJECT |
TOTAL FUNDING |
|
PI21/01631 |
EFECTOS CLÍNICOS Y FISIOLÓGICOS DEL METOPROLOL EN EL SÍNDROME DE DISTRÉS RESPIRATORIO AGUDO. METDIS |
SANTOS OVIEDO, ARNOLDO DE JESUS |
CLINICAL RESEARCH PROJECTS. ISCIII |
€101,640.00 |
PRIVATE
|
REFERENCE |
PROJECT TITLE |
PRINCIPAL RESEARCHER |
TYPE OF PROJECT |
|
2021/026 |
VALIDACIÓN DE UNA HERRAMIENTA DE MONITORIZACIÓN CONTINUA DE LAS |
SANTOS OVIEDO, ARNOLDO DE JESUS |
RESEARCH PROJECTS. COMPETITIVE |
|
2024.112 |
ANÁLISIS DEL PERFIL DE PACIENTES DIAGNOSTICADOS CON TROMBOCITOPENIA INMUNE PRIMARIA EN EL HOSPITAL |
BECARES MARTÍNEZ, JAVIER |
RESEARCH PROJECTS. |
|
2025.018 |
PROYECTO AFAPEAH ASTRAZENECA- DR. BECARES |
BECARES MARTÍNEZ, JAVIER |
RESEARCH PROJECTS. |
|
4749/017 |
ATENCIÓN FARMACÉUTICA EN PACIENTES EXTERNOS: ADHERENCIA EN TERAPIAS BIOLÓGICAS |
BECARES MARTÍNEZ, JAVIER |
RESEARCH PROJECTS. |
|
2024.095 |
EVALUACIÓN DEL VALOR TERAPÉUTICO Y DIAGNÓSTICO DE NOVEDOSAS NANOPARTÍCULAS LIPÍDICAS (OHMLINE) EN TUMORES PRIMARIOS (MELANOMA) Y METASTÁTICOS DE RATÓN |
CARNERO GUERRERO, CARLOS |
RESEARCH PROJECTS. |
|
2024.094 |
CÁTEDRA DE NEUROINTERVENCIONISMO UAM-FIIS-FJD |
RODRIGUEZ FERNANDEZ, CLAUDIO |
RESEARCH PROJECTS. |
|
19318/001 |
RECUPERACIÓN FUNCIONAL DEL MAYOR HOSPITAL DE DÍA DE GERIATRÍA HOPITAL UNIVERSITARIO INFANTA ELENA VALDEMORO |
HERRERA ABIAN, MARIA |
PERSONNEL/HUMAN RESOURCES |
|
EOH008-23_FJD |
ESTUDIO OBSERVACIONAL PARA EVALUAR LA ADHERENCIA A TREMFYA® (GUSELKUMAB) EN LA PRÁCTICA CLÍNICA EN PACIENTES CON PSORIASIS MODERADA A GRAVE |
BECARES MARTÍNEZ, JAVIER |
OBSERVATIONAL STUDIES |
|
EOH103-20_FJD |
EVOLUCIÓN DE LA EPIDEMIOLOGIA DE LA ENFERMEDAD CELÍACA Y FACTORES QUE DETERMINAN CAMBIOS EN LA PREVALENCIA DE LA ENFERMEDAD |
FARRAIS VILLALBA, SERGIO |
OBSERVATIONAL STUDIES |
|
EO150-21_FJD |
ESTRATEGIA DE BUSQUEDA DE PACIENTES CON DIAGNÓSTICO DE HEPATITIS C "PERDIDOS" EN EL SISTEMA. ESTABLECIMIENTO DE PROTOCOLO DE IDENTIFICACIÓN Y CONTACTO DE ESTOS PACIENTES |
RIOS LEON, RAQUEL |
OBSERVATIONAL STUDIES |
|
EOH032-25_FJD |
SAFETY AND EFFECTIVENESS OF THE SILK VISTA FLOW DIVERTER IN THE TREATMENT OF UNRUPTURED INTRACRANIAL ANEURYSMS (STREAM) |
RODRIGUEZ FERNANDEZ, CLAUDIO |
OBSERVATIONAL STUDIES |
|
EOH005-19_FJD |
ESTUDIO PRO (DESENLACES RETROSPECTIVOS DE PRECISIÓN) |
RUIZ NIETO, MARIA LUISA |
OBSERVATIONAL STUDIES |
|
00400040 |
II JORNADA DE ACTUALIZACIÓN EN GASTROENTEROLOGÍA PARA ATENCIÓN PRIMARIA (JUEVES, 29 DE MAYO DE 2025) |
BOSCH ESTEVA, ORENCIO |
TRAINING/TEACHING |
|
00400033 |
EANM FOCUS MEETING |
MARTÍNEZ DHIER, LUIS |
TRAINING/TEACHING |
|
00400028 |
FORMACIÓN DE PROFESIONALES SANITARIOS DEL SERVICIO DE ANESTESIA DEL HUFJD |
MUÑOZ ALAMEDA, LUIS ENRIQUE |
TRAINING/TEACHING |
Clinical trials
The clinical trials listed below were in the recruitment phase in 2025. If you are interested in participating in any of the currently open trials, more information is available on the website (https://ensayos.quironsalud.es/)
|
EudraCT Number |
TITLE |
PHASE |
MC1 |
INT2 |
PRINCIPAL RESEARCHER |
|
2020-000082-16 |
ESTUDIO ALEATORIZADO, DOBLE CIEGO Y CONTROLADO CON PLACEBO QUE EVALÚA LA EFICACIA, TOLERABILIDAD Y SEGURIDAD DE ESO-101 EN PACIENTES ADULTOS CON ESOFAGITIS EOSINOFÍLICA ACTIVA |
II |
YES |
YES |
LEONARDO BLAS JHON |
|
2024-510849-34-00 |
A PHASE 2, RANDOMIZED, DOUBLE-BLIND, MULTICENTER, PLACEBO-CONTROLLED STUDY WITH AN OPEN LABEL EXTENSION TO INVESTIGATE THE EFFICACY AND SAFETY OF SOLRIKITUG IN ADULTS WITH EOSINOPHILIC ESOPHAGITIS (ALAMERE) |
II |
YES |
YES |
LEONARDO BLAS JHON |
|
2023-506150-21-00 |
ENSAYO DE FASE II, DOBLE CIEGO, ALEATORIZADO Y CONTROLADO CON PLACEBO PARA EVALUAR LA EFICACIA Y TOLERABILIDAD DE ZED1227 EN SUJETOS CON ENFERMEDAD CELÍACA QUE PADECEN SÍNTOMAS A PESAR DE UNA DIETA SIN GLUTEN |
II |
YES |
YES |
SERGIO FARRAIS VILLALBA |
|
2020-004210-35 |
ENSAYO ABC-HCC: ENSAYO EN FASE IIIB, ALEATORIZADO, MULTICÉNTRICO Y ABIERTO DE ATEZOLIZUMAB MÁS BEVACIZUMAB FRENTE A QUIMIOEMBOLIZACIÓN TRANSARTERIAL (QETA) EN CARCINOMA HEPATOCELULAR EN ESTADIO INTERMEDIO |
III |
YES |
YES |
BENJAMIN POLO LORDUY |
|
2020-001314-37 |
ENSAYO DE FASE III A DOBLE CIEGO, DOBLE SIMULACIÓN, ALEATORIZADO, DE GRUPOS PARALELOS Y SIN PRIORIDADES, SOBRE LA EFICACIA Y LA TOLERABILIDAD DE 2 MG UNA VEZ AL DÍA FRENTE A 1 MG DOS VECES AL DÍA DE COMPRIMIDOS ORODISPERSABLES DE BUDESONIDA PARA LA INDUCCIÓN DE LA REMISIÓN HISTOLÓGICA EN ADULTOS CON ESOFAGITIS EOSINOFÍLICA |
III |
YES |
YES |
LEONARDO BLAS JHON |
|
2023-507473-17-00 |
A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PROGRAM TO EVALUATE THE EFFICACY AND SAFETY OF MK-7240 IN PARTICIPANTS WITH MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS |
III |
YES |
YES |
ORENCIO BOSCH ESTEVA |
|
2023-509606-30-00 |
A RANDOMISED, DOUBLE-BLIND, DOUBLE-DUMMY, MULTICENTRE, PHASE III, NON INFERIORITY TRIAL OF AN ORAL MESALAZINE FORMULATION IN PATIENTS WITH ACTIVE MILD TO MODERATE ULCERATIVE COLITIS FOR THE INDUCTION OF REMISSION |
III |
YES |
YES |
ORENCIO BOSCH ESTEVA |
|
2024-518603-22-00 |
PROGRAMA DE FASE 3, ALEATORIZADO, DOBLE CIEGO, CONTROLADO CON PLACEBO PARA EVALUAR LA EFICACIA Y LA SEGURIDAD DE MK-7240 EN PARTICIPANTES CON COLITIS ULCEROSA ACTIVA DE MODERADA A GRAVE |
III |
YES |
YES |
ORENCIO BOSCH ESTEVA |
|
2021-003267-96 |
ENSAYO CLÍNICO ALEATORIZADO PARA EVALUAR LA UTILIDAD DEL GENOTIPADO DE CYP2D6 PARA MEJORAR LA EFICACIA Y LA SEGURIDAD DEL TRAMADOL EN EL TRATAMIENTO DEL DOLOR POSTOPERATORIO AGUDO |
IV |
YES |
NO |
DOLORES MARTINEZ PEREZ |
|
2024-518521-14-00 |
SEDACIÓN INHALADA EN EL ENFERMO CRÍTICO: ENSAYO CLÍNICO MULTICÉNTRICO Y ALEATORIZADO |
IV |
YES |
NO |
MANUEL PEREZ TORRES |
|
NA |
INDIVIDUALIZED PERIOPERATIVEOPEN LUNG VENTILATORY APPROACH IN EMERGENCY ABDOMINAL LAPARO-TOMY/SCOPY. A PROSPECTIVE MULTICENTER RANDOMIZED CONTROLLED TRIAL |
NA |
YES |
NO |
SOLEDAD BELLAS COTAN |
|
NA |
EFECTIVIDAD Y EFICIENCIA DE LOS SISTEMAS DE RETORNO DE SANGRE EN EL PACIENTE CRÍTICO ADULTO: ENSAYO CLÍNICO MULTICÉNTRICO ALEATORIZADO |
NA |
YES |
NO |
SONIA LOPEZ CUENCA |
|
MC1: MULTICENTRE INT2: INTERNATIONAL |
|||||
Patents (revisar)
Title: Obturador rectal para cirugía proctológica.
Application No: U201831943
Main entities: FIIS-FJD (100%)
Inventors: Carlos García Vásquez, Santos Jiménez De Los Galanes Marchán, Pedro Pacheco Martínez.
Title: Sistema configurado para la implantación de un material protésico en pacientes que sufren una patología quirúrgica de la pared abdominal.
Application No: P202130319
Main entities: FIIS-FJD (100%)
Inventors: Carlos García Vásquez; Santos Jiménez de los Galanes Marchán; Pedro Pacheco Martínez.
Title: System configured for the implantation of a prosthetic material in patients suffering from a surgical pathology in the abdominal wall.
Application No: PCT/ES2022/070218
Main entities: FIIS-FJD (100%)
Inventors: Carlos García Vásquez; Santos Jiménez de los Galanes Marchán; Pedro Pacheco Martínez.
Title: Method for estimating the ventricular stroke volume from the pulmonary artery pressure.
Application No: EP23382143.8
Main entities: FIIS-FJD (80%), CIBER (10%), CIC BIOMAGUNE (10%)
Inventors: Arnoldo Santos Oviedo, Jesús María Ruiz-Cabello Osuna.
Intellectual Property Registrations
Title: Proyecto STIQ: Cirugía segura, afectiva y efectiva.
Código identificativo: 08bf4f4120b8d390f4450932402e2ee37f0eaadc45705afd4462ac3c2126a6f1
Centro: HURJC
Autor/es: Lorena Pingarrón y Dolores Martín Ríos.










