Data update as of 31/12/2025


Innovación médica y quirúrgica-01Innovación médica y quirúrgica-01
2025 DATA

Leaders



PI

  • Arnoldo de Jesún Sántos Oviedo

Research

  • Basic
  • Clinical

Location

Department of Anaesthesiology, Critical Care and Pain Medicine, 3rd floor

Fundación Jiménez Díaz University Hospital.

Avda. Reyes Católicos, 2. 28040 Madrid (Spain).


Keywords

Technology, organisational innovation, automation, surgical management, complexity, efficiency, surgical scheduling, and organisational models.



Gender perspective

Innovación médica y quirúrgica-02Innovación médica y quirúrgica-02


Summary of activities

The group focuses on the application of technology to the study of advanced life support in patients with severe multiorgan diseases and on the development of new mechanical ventilation strategies. Research activities also include the analysis of acute haemorrhage using thromboelastographyy, to reduce bleeding and to minimise the use of blood product transfusions. In addition, the group has incorporated ultrasound into both intraoperative and immediate postoperative patient care to assess haemodynamic instability and facilitate prompt diagnosis, enabling the rapid implementation of appropriate therapeutic interventions.


Contributions to society

All scientific activities conducted by the Medical and Surgical Innovation group are directly aimed at improving patient outcomes and generating benefits for society.


Collaborations

The Medical and Surgical Innovation group collaborates closely with the New Therapies Research group through the incorporation of computer-assisted analysis for the treatment of facial deformities and for the diagnosis and management of dysphagia. The group also contributes to the development of prognostic tools for chronic hepatitis, acute lung injury and acute kidney injury associated with sepsis.


PhD Theses

Innovación médica y quirúrgica-03Innovación médica y quirúrgica-03


List of publications

Palliative care training in Spanish Emergency Services: identifying needs and opportunities - a cross-sectional study.

Lobo-Antuña M, Lobo-Antuña V, Paredes-Coronel C, García-Romo E.

Eur J Emerg Med. 2026 Feb 01.33(1):54-56.

PMID: 41459602

FI: 4,2

http://dx.doi.org/10.1097/MEJ.0000000000001283This link opens in a popup window


Bone mineral density and trabecular bone score in Spanish postmenopausal osteoporosis-free women: correlation with demographic factors.

M Diaz-Curiel, JL Neyro, M Andrade-Poveda, I Mahillo-Fernandez.

Rev Osteoporosis Metab Miner. 2025;17(2):84-89.

PMID: 10.20960/RevOsteoporosMetabMiner.00073

FI: 0,5

http://dx.doi.org/10.20960/RevOsteoporosMetabMiner.00073This link opens in a popup window


Overview of the multidisciplinary team activity in patients with hepatocellular carcinoma and their survival outcomes.

Guarini V, Garzòn C, Casado D, Casanova M, Villarejo P, Azinovic I, Crespo E, Fernandez I, Lopez M, de Bourio MM, Moran M, Jimenez M, Medrano G, Castellano V, Lamarca A.

ESMO Gastrointest Oncol. 2025 Dec.10 (2025): 100263.

PMID: 10.1016/j.esmogo.2025.100263

FI: 0

http://dx.doi.org/10.1016/j.esmogo.2025.100263This link opens in a popup window


Experimental determination of effective X-ray attenuation coefficients of 3D-printed materials under clinical mammography spectra.

Belarra A, Hernández-Girón I, Garayoa J, Martínez LC, Valverde J, Rot MJ, Ferrando A, Martín A, Chevalier M.

Front Bioeng Biotechnol. 2025.13:1719551.

PMID: 41725985

FI: 4,8

http://dx.doi.org/10.3389/fbioe.2025.1719551This link opens in a popup window


Acute gluten-induced inflammatory response highlights CCL20 as a potential biomarker for celiac disease.

Gómez-Aguililla S, Farrais S, López-Palacios N, Arau B, Senosiain C, Infante-Menéndez J, Ruiz-Carnicer Á, Fernández-Bañares F, González-López N, Pujals M, Sousa C, Núñez C.

Front Immunol. 2025.16:1745890.

PMID: 41601633

FI: 5,9

http://dx.doi.org/10.3389/fimmu.2025.1745890This link opens in a popup window


Hepatocellular carcinoma in non-cirrhotic liver: a prospective Spanish multicenter study.

Romero Gutiérrez M, Pascual S, Gómez-Rubio M, Aracil C, Márquez L, Piqueras B, Bernal-Monterde V, Ferrer T, Miquel M, Fernández C, González-Santiago JM, Horta D, Alarcón C, Martín A, Latorre R, Gutiérrez ML, Rendón P, Blanco-Sampascual S, Testillano M, Hernández-Guerra M, Tejedor M, Delgado C, Matilla A, Gómez Rodríguez R.

Rev Esp Enferm Dig. 2025 Dec 18.

PMID: 41410255

FI: 4

http://dx.doi.org/10.17235/reed.2025.11674/2025This link opens in a popup window


Machine learning-based treatment outcome prediction in head and neck cancer using integrated noninvasive diagnostics.

Yeghaian M, Trebeschi S, Herrero-Huertas M, Ferradás FJM, Bos P, van Alphen MJA, van Gerven MAJ, Beets-Tan RGH, Bodalal Z, van der Velden LA.

Int J Comput Assist Radiol Surg. 2025 Dec 08.

PMID: 41359226

FI: 2,3

http://dx.doi.org/10.1007/s11548-025-03539-2This link opens in a popup window


OBE-DIGITHUM: A Clinician-Led Digital Pathway for Sustainable Obesity Care-A Perspective.

Montoya T, Cárdenas JJ, Luca BL, Paniagua A, García-Valdecasas L, Reigosa L, Cruz S, Mas-Fontao S, Sierra R, Pérez de Arenaza V, Aganzo M, Gómez-Meana Á, Izquierdo I, Vázquez C.

Obes Rev. 2025 Dec 02:e70042.

PMID: 41330569

FI: 7,4

http://dx.doi.org/10.1111/obr.70042This link opens in a popup window


Uses and technique of ultrasound-guided botulinum toxin infiltration.

Llorente Peris J, Miranda Bautista J, Menéndez Fernández-Miranda P.

Radiologia (Engl Ed). 2025.67(6):501695.

PMID: 41224378

FI: 1,1

http://dx.doi.org/10.1016/j.rxeng.2025.501695This link opens in a popup window


Exploratory integration of near-infrared spectroscopy with clinical data: a machine learning approach for HCV detection in serum samples.

Pérez-Gómez E, Gómez J, Gonzalo J, Salgüero S, Riado D, Casas ML, Gutiérrez ML, Jaime E, Pérez-Martínez E, García-Carretero R, Ramos J, Fernández-Rodríguez C, Catalá M, Martino L, Barquero-Pérez Ó.

Front Med (Lausanne). 2025.12:1596476.

PMID: 40552174

FI: 3

http://dx.doi.org/10.3389/fmed.2025.1596476This link opens in a popup window


Ultrasound-guided postmortem biopsies in the ICU: diagnostic yield and future applications beyond the pandemic.

Vidal González Á, Páez Vargas JJ, Robaglia D, Vicente Montaña AM, Fortes Alen JR, Prieto Pérez L.

Med Intensiva (Engl Ed). 2025 Nov 26:502362.

PMID: 41309369

FI: 3,1

http://dx.doi.org/10.1016/j.medine.2025.502362This link opens in a popup window


Predicting Outcome and Duration of Mechanical Ventilation in Acute Hypoxemic Respiratory Failure: The PREMIER Study.

Villar J, González-Martín JM, Fernández C, Soler JA, Rey-Abalo M, Mora-Ordóñez JM, Ortiz-Díaz-Miguel R, Fernández L, Murcia I, Robaglia D, Añón JM, Ferrando C, Parrilla D, Dominguez-Berrot AM, Cobeta P, Martínez D, Amaro-Harpigny A, Andaluz-Ojeda D, Fernández MM, Gómez-Bentolila E, Steyerberg EW, Camporota L, Szakmany T.

J Clin Med. 2025 Nov 07.14(22).

PMID: 41302939

FI: 2,9

http://dx.doi.org/10.3390/jcm14227903This link opens in a popup window


Economic burden of eosinophilic esophagitis in the first year after diagnosis in Spain: A direct medical cost analysis.

Rodriguez-Alcolado L, Aranda-Reneo I, Casabona S, Pérez-Martínez I, Guagnozzi D, Gutiérrez-Junquera C, Amorena E, Guardiola-Arévalo A, de la Peña-Negro L, Jhon LB, García-Dionisio SL, Fernández-Pacheco J, Barrio J, Fernández-Fernández S, Betoré E, de la Riva S, Teruel Sánchez-Vegazo C, Rodríguez-Oballe JA, Naves JE, Bisso-Zein JK, Carrión S, Suárez A, Llerena-Castro R, García-Díaz A, Nantes-Castillejo Ó, Granja-Navacerrada A, Perelló A, Álvarez-García M, Santander C, Laserna-Mendieta EJ, Oliva-Moreno J, Lucendo AJ.

Eur J Health Econ. 2025 Nov 18.

PMID: 41252104

FI: 3

http://dx.doi.org/10.1007/s10198-025-01872-6This link opens in a popup window


Evaluation of adherence to the gluten-free diet in adolescent and adult patients with coeliac disease: a strategy based on the determination of gluten immunogenic peptides endorsed by the Spanish Society of Coeliac Disease (SEEC).

Pizarro Moreno Á, Garzón Benavides M, Comino I, Donat E, Farrais Villalba S, Fernández Salazar L, Molero M, Montoro Huguet M, Ribes-Koninckx C, Santolaria S, Simón E, Sousa C, Vivas S, Núñez C.

Rev Esp Enferm Dig. 2025 Nov 17.

PMID: 41247357

FI: 4

http://dx.doi.org/10.17235/reed.2025.11519/2025This link opens in a popup window


Postmortem ultrastructural lung and liver injury in a critically ill COVID-19 patient.

González ÁV, Montaña AM, Piris MC, Prieto-Pérez L.

BMJ Case Rep. 2025 Nov 12.18(11).

PMID: 41224683

FI: 0,5

http://dx.doi.org/10.1136/bcr-2025-267289This link opens in a popup window


When magnetic resonance imagin shows what sodium doesn't: Beyond osmotic imbalance in central pontine myelinolysis.

Maqueda Lluva D, Garrido Callén A, Pérez Torres M.

Med Intensiva (Engl Ed). 2025 Nov 07:502297.

PMID: 41206340

FI: 3,1

http://dx.doi.org/10.1016/j.medine.2025.502297This link opens in a popup window


Design and implementation of a lomustine circuit as a safe practice.

Barreras Ruiz N, Ortega Menendez P, Jiménez Navarro L, Blanco Saiz E, Bonilla Porras M, Bécares Martinez J.

J Oncol Pharm Pract. 2025 Nov 06:10781552251393175.

PMID: 41197234

FI: 0,9

http://dx.doi.org/10.1177/10781552251393175This link opens in a popup window


Maternal experience in the intensive care unit and post-discharge care: the third report from the MaCriCare study.

Cantellow S, Balcerzak Ł, Schyns-van den Berg A, Dabrowska D, Guasch E, Jörnvall H, Lucas N, Mercier FJ, Weiniger CF, Krawczyk P, MaCriCare Study Group.

Int J Obstet Anesth. 2025 Nov.64:104737.

PMID: 40782693

FI: 2,3

http://dx.doi.org/10.1016/j.ijoa.2025.104737This link opens in a popup window


Effects of an Electronic Patient Reported Outcome Measures (e-PROMs) Program on Symptom Reporting, Use of Healthcare, and Overall Survival in Patients With Lymphoma: A Multicenter Prospective Study.

Córdoba R, Del Olmo Rodríguez M, Ramos S, López García A, Morillo D, Pérez-Sáenz MA, Miranda C, Martos R, Beltrán L, Castillo E, Herrero A, Gómez-Meana A, Pfang B, Short Apellaniz J, Arcos-Campillo J.

EJHaem. 2025 Oct.6(5):e70129.

PMID: 40909396

FI: 1,2

http://dx.doi.org/10.1002/jha2.70129This link opens in a popup window


Differences in histopathologic features and diagnostic performance of 99mTc-methoxy-isobutyl-isonitrol single photon emission tomography-CT and 18F-fluorocholine positron emission tomography-CT in primary hyperparathyroidism.

Osorio-Silla I, González DM, Quiceno Arias HD, Peinado PP, Cárdenas Salas JJ, González MM, Pestana Soares CA, Martínez Ruiz LF, Landaeta Kancev LC, Dhier LM, Escanciano M, Sánchez de Molina ML, Ruíz AP, Campos PV.

Surgery. 2025 Oct.186:109595.

PMID: 40782725

FI: 2,7

http://dx.doi.org/10.1016/j.surg.2025.109595This link opens in a popup window


Analgesic Effect of a Novel Intravenous Ibuprofen-Low-Dose Tramadol Combination: A Multimodal Approach to Moderate-to-Severe Postoperative Dental Pain.

Salas-Butrón MR, Laredo-Velasco L, Rivas-Paterna AB, González-Corchon A, Muñoz-Guerra MF, Borobia AM, Acero-Sanz JJ, Pérez-Ingidua C, Abad-Santos F, Cebrián JL, Gálvez-Múgica MÁ, Serrano-García I, Portolés-Díez C, Llanos L, Martínez D, Sanz N, Calandria C, Vargas-Castrillón E, Martín-Granizo R, Portolés-Pérez A.

Pharmaceutics. 2025 Sep 24.17(10).

PMID: 41155885

FI: 5,5

http://dx.doi.org/10.3390/pharmaceutics17101248This link opens in a popup window


The World Federation Societies of Anaesthesiologists' (WFSA) declaration on patients' right to labour analgesia: raising awareness and elevating the role of anaesthesiologists in global maternal health.

Guasch E, George RB.

Int J Obstet Anesth. 2025 Sep 29.65:104784.

PMID: 41061387

FI: 2,3

http://dx.doi.org/10.1016/j.ijoa.2025.104784This link opens in a popup window


Diagnostic value and clinical implications of 75SeHCAT scan in bile acid diarrhea.

Riado Mínguez D, Fernández-Gordón FM, Casado Portolés M, Gómez Labrador C, Cuadrado Tiemblo C, Suárez Cabredo CG, Wong Becerra LW, Castaño Milla C.

Gastroenterol Hepatol. 2025 Sep 24:502584.

PMID: 41005651

FI: 1,9

http://dx.doi.org/10.1016/j.gastrohep.2025.502584This link opens in a popup window


More than step counts: Slow walking speed, limited running, and fewer long walks predict cardiovascular mortality in the Walk Watch UK Biobank study.

Herrero Pinilla B, Hong S, Brodie MA, Lord SR, Chan LLY.

J Gerontol A Biol Sci Med Sci. 2025 Sep 19.80(10).

PMID: 40845147

FI: 3,8

http://dx.doi.org/10.1093/gerona/glaf184This link opens in a popup window


Shocking evidence to diminish fibrosis after lipedema reductive surgery.

Reyes Valdivia A, Chuquisana C.

Phlebology. 2025 Aug 10:2683555251369082.

PMID: 40785137

FI: 1,5

http://dx.doi.org/10.1177/02683555251369082This link opens in a popup window


Environmental sustainability in intensive care: An international survey of intensive care professionals'views, practices and proposals to the European Society of Intensive Care Medicine.

Iliopoulou K, Leone M, Hunfeld N, Ferrer R, Baid H, Ostermann M, Scaramuzzo G, Touw H, Ioan AM, Theodorakopoulou M, Francois G, De Waele JJ.

J Crit Care. 2025 Aug.88:155079.

PMID: 40267551

FI: 2,9

http://dx.doi.org/10.1016/j.jcrc.2025.155079This link opens in a popup window


ESAIC Mellin-Olsen declaration on diversity, equity and inclusion.

Gisselbaek M, Saxena S, Berger-Estilita J, Ateleanu B, Brazzi L, Buhre W, Crisan I, Camilleri-Podesta AM, Coburn M, Durnev V, Filipescu D, Ghezel-Ahmadi D, Golubovska I, Arévalo EG, Honorato-Cia C, Klimek M, Meco BC, Myatra SN, Nahtomi-Shick O, Neskovic V, O'Sullivan E, Rubulotta F, Romero C, Sabelnikovs O, Struys MM, Südy R, Weynants C, Ringvold EM, Matot I.

Eur J Anaesthesiol. 2025 Jul 01.42(7):579-583.

PMID: 40314611

FI: 6,8

http://dx.doi.org/10.1097/EJA.0000000000002186This link opens in a popup window


Effects of a nationwide teledermatology program on access to care for skin cancer and premalignant lesions in public and private health care: A retrospective case-control analysis of data from eight Spanish hospitals.

Toledo-Pastrana T, Mora D, Martin-Gutierrez F, Fernández Valdés-Martín C, Corrales-Rodriguez A, Pfang B, Villegas García MA, Alcaraz-Leon I, Vicente J, Short Apellániz J, Blanco Rubio A, Herrero A, Del Olmo M, Álvaro de la Parra JA.

J Am Acad Dermatol. 2025 Jul.93(1):281-283.

PMID: 40120816

FI: 11,8

http://dx.doi.org/10.1016/j.jaad.2025.03.037This link opens in a popup window


A Data-Centric Approach to Deep Learning for Brain Metastasis Analysis at MRI.

Topff L, Petrychenko L, Jain N, Lingier S, Bertels J, Astudillo P, Prosec M, Menéndez Fernández-Miranda P, Gevaert O, Smits M, Derks S, Verhaak E, Hanssens PEJ, Marco de Lucas E, Sutil R, Dominguez PD, Negoita A, Visser E, Corral Fontecha D, Braun LMM, Brandsma D, Visser JJ, Ranschaert ER, Groot Lipman KBW, Beets-Tan RGH.

Radiology. 2025 Jun.315(3):e242416.

PMID: 40552999

FI: 15,2

http://dx.doi.org/10.1148/radiol.242416This link opens in a popup window


Guidelines on strategies for the universal implementation of videolaryngoscopy.

Gómez-Ríos MÁ, Van Zundert AAJ, McNarry AF, Law JA, Higgs A, De Jong A, Jaber S, Karamchandani K, Hansel J, Saracoglu KT, Leach R, Guimaraes HP, Abad-Gurumeta A, Gómez-Ríos D, Michalek P, Berkow LC, Fernández-Vaquero MÁ, Serrano-Moraza A, Gaitini L, Vaida S, Somri M, Gaszyński T, Brewster D, Desai N, Saracoglu A, Tsan SEH, Athanassoglou V, Komasawa N, Garg R, Shamim F, Rajendram R, Gutierrez-Couto U, López T, De Luis-Cabezón N, Flores DT, Garzón JC, Sastre JA, Roca de Togores López A, Meléndez-Salinas D, Fandiño-Orgeira JM, Casans-Frances R, Casalderrey-Rivas M, Romero-García E, Marín-Zaldívar C, Aroca-Tanarro A, Alonso-Correa O, Rodríguez-Martín LJ, Espinosa-Ramírez S, Hagberg CA.

Eur J Anaesthesiol. 2025 Jun 19.

PMID: 40534455

FI: 6,8

http://dx.doi.org/10.1097/EJA.0000000000002210This link opens in a popup window


Anaesthetic strategies for managing placenta accreta spectrum with REBOA: Insights from an international multicentre retrospective study.

Azem K, Orbach-Zinger S, Ioscovich A, Brogly N, Spiegel E, Shoham A, Shatalin D, Valbuena I, Frenkel A, Isasi LMV, Matatov Y, Fein S, Greenman D, Neeman Y, Guasch E, Binyamin Y.

Eur J Anaesthesiol. 2025 Jun 06.

PMID: 40474704

FI: 6,8

http://dx.doi.org/10.1097/EJA.0000000000002218This link opens in a popup window


Dermatologists' perception of teledermatology and risk factors for burnout: A cross-sectional study.

Toledo Pastrana T, Paredes Coronel C, Martín Gutiérrez FJ, Fernández-Martín Valdés C, Corrales Rodríguez A, Aspe Unanue L, Casulleras González A, Alcántara Reifs C, Bota Llorca A, Ortega Berbel L, Dios Guillan V, Short Apellaniz J, Del Olmo Rodriguez M, Pfang B, DermaON Quirónsalud Teledermatology Response Group.

J Eur Acad Dermatol Venereol. 2025 May 07.

PMID: 40331887

FI: 8

http://dx.doi.org/10.1111/jdv.20715This link opens in a popup window


Revisiting artifact spread function evaluation in digital breast tomosynthesis systems.

Ovejero JG, Alarcia M, Barba JC, Cabañero B, Cuesta JA, García-Sanz A, Megías JM, Garayoa J, Chevalier M.

Phys Med. 2025 May.133:104982.

PMID: 40279988

FI: 2,7

http://dx.doi.org/10.1016/j.ejmp.2025.104982This link opens in a popup window


Effectiveness and safety of rectal tacrolimus in patients with ulcerative colitis. TACRO-TOPIC study of GETECCU.

Fuentes-Valenzuela E, Bastón-Rey I, García-Alonso FJ, Elosua A, Zabalza San Martín L, Leo Carnerero E, Garcia de la Filia I, Pedraza Pérez A, Sáiz Chumillas RM, Pascual Oliver A, Muñoz Villafranca C, Moreno V, Suárez Ferrer C, Molina G, Ferreiro-Iglesias R, Vega Villaamil P, Gardeazábal Mateos D, Segarra-Ortega JX, Garrido Marín A, Doallo AI, Alonso-Galán H, Brunet-Mas E, Jimenez García N, López Romero-Salazar F, Velayos B, Carballo-Folgoso L, Pérez Santamaría C, Mata Román L, Núñez Ortiz A, Barrio J, Barreiro-de Acosta M, Gutiérrez-Casbas A.

J Crohns Colitis. 2025 May 08.19(5).

PMID: 40205922

FI: 8,7

http://dx.doi.org/10.1093/ecco-jcc/jjaf058This link opens in a popup window


Towards a practice of neuraxial blocks under real-time ultrasound guidance: from preprocedural screening to direct guidance.

Brogly N, Guasch E.

Minerva Anestesiol. 2025 May.91(5):370-372.

PMID: 40047524

FI: 2,8

http://dx.doi.org/10.23736/S0375-9393.25.18903-7This link opens in a popup window


Iron deficiency and anemia in pregnancy: a call to action!: -""If you don't take a temperature, you can't find a fever"".

Kranke P, Weiniger CF, Sultan P, Achebe MO, Filipescu D, Brogly N, Surbek D, Lasocki S, Guasch E, Meybohm P.

Int J Obstet Anesth. 2025 May.62:104298.

PMID: 39987638

FI: 2,3

http://dx.doi.org/10.1016/j.ijoa.2024.104298This link opens in a popup window


Effects of Virtually Led Value-Based Preoperative Assessment on Safety, Efficiency, and Patient and Professional Satisfaction.

Martínez JLG, Coca MÁM, Del Olmo Rodríguez M, Vigoa P, Gómez JM, Apellaniz JS, Coronel CP, García MAV, Serrano JJ, Arcos J, Caramés Sánchez C, Pfang B, Álvaro de la Parra JA.

J Clin Med. 2025 Apr 29.14(9).

PMID: 40364124

FI: 2,9

http://dx.doi.org/10.3390/jcm14093093This link opens in a popup window


Prevalence and evolution of newly diagnosed autoimmune gastritis in a large Spanish retrospective cohort.

Fuentes-Valenzuela E, Escribano Cruz S, Parra Villanueva J, Calvache Rodríguez A, Gil Díaz A, López-Martín MDC, Rubio de la Plaza I, Blanco S, Chivato Martín-Falquina I, Rodríguez-Batllori Aran B, Latorre Martinez R, Castillo Herrera LA, Olvera R, Alcalde Rodríguez D, Guzmán López K, Bejerano Domínguez A.

Rev Esp Enferm Dig. 2025 Apr 25.

PMID: 40276987

FI: 4

http://dx.doi.org/10.17235/reed.2025.11101/2025This link opens in a popup window


Management of postoperative pain after cesarean section: advances in ultrasound-guided regional blocks.

Brogly N, Guasch E.

Minerva Anestesiol. 2025 Apr 23.

PMID: 40265501

FI: 2,8

http://dx.doi.org/10.23736/S0375-9393.25.19016-0This link opens in a popup window


Elucidating Immune Cell Changes in Celiac Disease: Revealing New Insights from Spectral Flow Cytometry.

Gómez-Aguililla S, Farrais S, Senosiain C, López-Palacios N, Arau B, Ruiz-Carnicer Á, Sánchez-Domínguez R, Corzo M, Casado I, Pujals M, Bodas A, Sousa C, Núñez C.

Int J Mol Sci. 2025 Mar 21.26(7).

PMID: 40243487

FI: 4,9

http://dx.doi.org/10.3390/ijms26072877This link opens in a popup window


Follow-up in coeliac disease: evidence and future challenges.

Castañeda Agredo A, Farrais Villalba S, Sanders DS.

Rev Esp Enferm Dig. 2025 Mar 27.

PMID: 40145902

FI: 4

http://dx.doi.org/10.17235/reed.2025.11168/2025This link opens in a popup window


Diagnosis of celiac disease on a gluten-free diet: a multicenter prospective quasi-experimental clinical study.

Gómez-Aguililla S, Farrais S, López-Palacios N, Arau B, Senosiain C, Corzo M, Fernandez-Jimenez N, Ruiz-Carnicer Á, Fernández-Bañares F, González-García BP, Tristán E, Montero-Calle A, Garranzo-Asensio M, Casado I, Pujals M, Hernández JM, Infante-Menéndez J, Roy G, Sousa C, Núñez C.

BMC Med. 2025 Mar 26.23(1):182.

PMID: 40140887

FI: 8,3

http://dx.doi.org/10.1186/s12916-025-04008-yThis link opens in a popup window


Predictive factors of gait recovery after hip fracture: a scoping review.

González de Villaumbrosia C, Barba R, Ojeda-Thies C, Grifol-Clar E, Álvarez-Diaz N, Álvarez-Espejo T, Cancio-Trujillo JM, Mora-Fernández J, Pareja-Sierra T, Barrera-Crispín R, Calle-Egusquiza A, Capdevila-Reniu A, Carrasco-Paniagua C, Cervera Díaz MC, Condorhuamán-Alvarado P, Cotano-Abad L, Cuadra-Llopart L, García-Cárdenas V, González-Chávez S, Hernández-Sánchez LA, Herrero-Pinilla B, López-Castro J, Montero-Fernández N, Muñoz-Pascual A, Muñoz-Vélez M, Ortés-Gómez R, Sáenz-Tejada A, Sanz-Reig J, Torras-Cortada S, Ramos Cortés M, Sáez-López P.

Age Ageing. 2025 Mar 03.54(3).

PMID: 40100147

FI: 7,1

http://dx.doi.org/10.1093/ageing/afaf057This link opens in a popup window


Early Prediction of ICU Mortality in Patients with Acute Hypoxemic Respiratory Failure Using Machine Learning: The MEMORIAL Study.

Villar J, González-Martín JM, Fernández C, Añón JM, Ferrando C, Mora-Ordoñez JM, Martínez D, Mosteiro F, Ambrós A, Fernández L, Murcia I, Vidal A, Pestaña D, Romera MA, Montiel R, Domínguez-Berrot AM, Soler JA, Gómez-Bentolila E, Steyerberg EW, Szakmany T.

J Clin Med. 2025 Mar 04.14(5).

PMID: 40095813

FI: 2,9

http://dx.doi.org/10.3390/jcm14051711This link opens in a popup window


ESAIC focused guidelines for the management of the failing epidural during labour epidural analgesia.

Brogly N, Valbuena Gómez I, Afshari A, Ekelund K, Kranke P, Weiniger CF, Lucas N, Dewandre PY, Guasch Arevalo E, Ioscovich A, Kollmann A, Lindelof K, Orbach-Zinger S, Reis S, van den Bosch O, Van de Velde M, Romero CS.

Eur J Anaesthesiol. 2025 Feb 01.42(2):96-112.

PMID: 39744744

FI: 6,8

http://dx.doi.org/10.1097/EJA.0000000000002108This link opens in a popup window


Capítulo 22 La gestión del servicio de medicina nuclear.

Martinez Dhier L.

. ISBN-9788490525562-22.

PMID: ISBN-9788490525562-22

FI: 0

http://dx.doi.org/ISBN-9788490525562-22This link opens in a popup window


To considerate perforation of duodenal diverticula.

Álvarez-García M, Milán Pilo MV, Otegui L, Calvo Hernández R, Polo B, Bosch Esteva O.

Rev Esp Enferm Dig. 2025 Jan 09.

PMID: 39784684

FI: 4

http://dx.doi.org/10.17235/reed.2024.10955/2024This link opens in a popup window


Implementing a closed loop clinical decision support system for sustainable preoperative care.

Gracia Martínez JL, Pfang B, Morales Coca MÁ, Caramés Sánchez C, Del Olmo Rodríguez M, Villegas García MA, Short Apellaniz J, Arcos Campillo J, Álvaro de la Parra JA, Manzano Lorefice F, Muñoz Alameda LE.

NPJ Digit Med. 2025 Jan 03.8(1):6.

PMID: 39753745

FI: 15,1

http://dx.doi.org/10.1038/s41746-024-01371-7This link opens in a popup window


Projects, contracts and observational studies

PUBLIC

Sources of public funding for projects being developed at the IIS-FJD:

:

_FINANCIACIÓN-261007_FINANCIACIÓN-261007

REFERENCE

PROJECT TITLE

PRINCIPAL RESEARCHER

TYPE OF PROJECT

TOTAL FUNDING

PI21/01631

EFECTOS CLÍNICOS Y FISIOLÓGICOS DEL METOPROLOL EN EL SÍNDROME DE DISTRÉS RESPIRATORIO AGUDO. METDIS

SANTOS OVIEDO, ARNOLDO DE JESUS

CLINICAL RESEARCH PROJECTS. ISCIII

€101,640.00

PRIVATE

REFERENCE

PROJECT TITLE

PRINCIPAL RESEARCHER

TYPE OF PROJECT

2021/026

VALIDACIÓN DE UNA HERRAMIENTA DE MONITORIZACIÓN CONTINUA DE LAS
INTERACCIONES CARDIOPULMONARES PARA OPTIMIZAR EL MANEJO DE PACIENTES EN CUIDADOS INTENSIVOS

SANTOS OVIEDO, ARNOLDO DE JESUS

RESEARCH PROJECTS. COMPETITIVE

2024.112

ANÁLISIS DEL PERFIL DE PACIENTES DIAGNOSTICADOS CON TROMBOCITOPENIA INMUNE PRIMARIA EN EL HOSPITAL

BECARES MARTÍNEZ, JAVIER

RESEARCH PROJECTS.

2025.018

PROYECTO AFAPEAH ASTRAZENECA- DR. BECARES

BECARES MARTÍNEZ, JAVIER

RESEARCH PROJECTS.

4749/017

ATENCIÓN FARMACÉUTICA EN PACIENTES EXTERNOS: ADHERENCIA EN TERAPIAS BIOLÓGICAS

BECARES MARTÍNEZ, JAVIER

RESEARCH PROJECTS.

2024.095

EVALUACIÓN DEL VALOR TERAPÉUTICO Y DIAGNÓSTICO DE NOVEDOSAS NANOPARTÍCULAS LIPÍDICAS (OHMLINE) EN TUMORES PRIMARIOS (MELANOMA) Y METASTÁTICOS DE RATÓN

CARNERO GUERRERO, CARLOS

RESEARCH PROJECTS.

2024.094

CÁTEDRA DE NEUROINTERVENCIONISMO UAM-FIIS-FJD

RODRIGUEZ FERNANDEZ, CLAUDIO

RESEARCH PROJECTS.

19318/001

RECUPERACIÓN FUNCIONAL DEL MAYOR HOSPITAL DE DÍA DE GERIATRÍA HOPITAL UNIVERSITARIO INFANTA ELENA VALDEMORO

HERRERA ABIAN, MARIA

PERSONNEL/HUMAN RESOURCES

EOH008-23_FJD

ESTUDIO OBSERVACIONAL PARA EVALUAR LA ADHERENCIA A TREMFYA® (GUSELKUMAB) EN LA PRÁCTICA CLÍNICA EN PACIENTES CON PSORIASIS MODERADA A GRAVE

BECARES MARTÍNEZ, JAVIER

OBSERVATIONAL STUDIES

EOH103-20_FJD

EVOLUCIÓN DE LA EPIDEMIOLOGIA DE LA ENFERMEDAD CELÍACA Y FACTORES QUE DETERMINAN CAMBIOS EN LA PREVALENCIA DE LA ENFERMEDAD

FARRAIS VILLALBA, SERGIO

OBSERVATIONAL STUDIES

EO150-21_FJD

ESTRATEGIA DE BUSQUEDA DE PACIENTES CON DIAGNÓSTICO DE HEPATITIS C "PERDIDOS" EN EL SISTEMA. ESTABLECIMIENTO DE PROTOCOLO DE IDENTIFICACIÓN Y CONTACTO DE ESTOS PACIENTES

RIOS LEON, RAQUEL

OBSERVATIONAL STUDIES

EOH032-25_FJD

SAFETY AND EFFECTIVENESS OF THE SILK VISTA FLOW DIVERTER IN THE TREATMENT OF UNRUPTURED INTRACRANIAL ANEURYSMS (STREAM)

RODRIGUEZ FERNANDEZ, CLAUDIO

OBSERVATIONAL STUDIES

EOH005-19_FJD

ESTUDIO PRO (DESENLACES RETROSPECTIVOS DE PRECISIÓN)

RUIZ NIETO, MARIA LUISA

OBSERVATIONAL STUDIES

00400040

II JORNADA DE ACTUALIZACIÓN EN GASTROENTEROLOGÍA PARA ATENCIÓN PRIMARIA (JUEVES, 29 DE MAYO DE 2025)

BOSCH ESTEVA, ORENCIO

TRAINING/TEACHING

00400033

EANM FOCUS MEETING

MARTÍNEZ DHIER, LUIS

TRAINING/TEACHING

00400028

FORMACIÓN DE PROFESIONALES SANITARIOS DEL SERVICIO DE ANESTESIA DEL HUFJD

MUÑOZ ALAMEDA, LUIS ENRIQUE

TRAINING/TEACHING


Clinical trials

The clinical trials listed below were in the recruitment phase in 2025. If you are interested in participating in any of the currently open trials, more information is available on the website (https://ensayos.quironsalud.es/)

EudraCT Number

TITLE

PHASE

MC1

INT2

PRINCIPAL RESEARCHER

2020-000082-16

ESTUDIO ALEATORIZADO, DOBLE CIEGO Y CONTROLADO CON PLACEBO QUE EVALÚA LA EFICACIA, TOLERABILIDAD Y SEGURIDAD DE ESO-101 EN PACIENTES ADULTOS CON ESOFAGITIS EOSINOFÍLICA ACTIVA

II

YES

YES

LEONARDO BLAS JHON

2024-510849-34-00

A PHASE 2, RANDOMIZED, DOUBLE-BLIND, MULTICENTER, PLACEBO-CONTROLLED STUDY WITH AN OPEN LABEL EXTENSION TO INVESTIGATE THE EFFICACY AND SAFETY OF SOLRIKITUG IN ADULTS WITH EOSINOPHILIC ESOPHAGITIS (ALAMERE)

II

YES

YES

LEONARDO BLAS JHON

2023-506150-21-00

ENSAYO DE FASE II, DOBLE CIEGO, ALEATORIZADO Y CONTROLADO CON PLACEBO PARA EVALUAR LA EFICACIA Y TOLERABILIDAD DE ZED1227 EN SUJETOS CON ENFERMEDAD CELÍACA QUE PADECEN SÍNTOMAS A PESAR DE UNA DIETA SIN GLUTEN

II

YES

YES

SERGIO FARRAIS VILLALBA

2020-004210-35

ENSAYO ABC-HCC: ENSAYO EN FASE IIIB, ALEATORIZADO, MULTICÉNTRICO Y ABIERTO DE ATEZOLIZUMAB MÁS BEVACIZUMAB FRENTE A QUIMIOEMBOLIZACIÓN TRANSARTERIAL (QETA) EN CARCINOMA HEPATOCELULAR EN ESTADIO INTERMEDIO

III

YES

YES

BENJAMIN POLO LORDUY

2020-001314-37

ENSAYO DE FASE III A DOBLE CIEGO, DOBLE SIMULACIÓN, ALEATORIZADO, DE GRUPOS PARALELOS Y SIN PRIORIDADES, SOBRE LA EFICACIA Y LA TOLERABILIDAD DE 2 MG UNA VEZ AL DÍA FRENTE A 1 MG DOS VECES AL DÍA DE COMPRIMIDOS ORODISPERSABLES DE BUDESONIDA PARA LA INDUCCIÓN DE LA REMISIÓN HISTOLÓGICA EN ADULTOS CON ESOFAGITIS EOSINOFÍLICA

III

YES

YES

LEONARDO BLAS JHON

2023-507473-17-00

A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PROGRAM TO EVALUATE THE EFFICACY AND SAFETY OF MK-7240 IN PARTICIPANTS WITH MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS

III

YES

YES

ORENCIO BOSCH ESTEVA

2023-509606-30-00

A RANDOMISED, DOUBLE-BLIND, DOUBLE-DUMMY, MULTICENTRE, PHASE III, NON INFERIORITY TRIAL OF AN ORAL MESALAZINE FORMULATION IN PATIENTS WITH ACTIVE MILD TO MODERATE ULCERATIVE COLITIS FOR THE INDUCTION OF REMISSION

III

YES

YES

ORENCIO BOSCH ESTEVA

2024-518603-22-00

PROGRAMA DE FASE 3, ALEATORIZADO, DOBLE CIEGO, CONTROLADO CON PLACEBO PARA EVALUAR LA EFICACIA Y LA SEGURIDAD DE MK-7240 EN PARTICIPANTES CON COLITIS ULCEROSA ACTIVA DE MODERADA A GRAVE

III

YES

YES

ORENCIO BOSCH ESTEVA

2021-003267-96

ENSAYO CLÍNICO ALEATORIZADO PARA EVALUAR LA UTILIDAD DEL GENOTIPADO DE CYP2D6 PARA MEJORAR LA EFICACIA Y LA SEGURIDAD DEL TRAMADOL EN EL TRATAMIENTO DEL DOLOR POSTOPERATORIO AGUDO

IV

YES

NO

DOLORES MARTINEZ PEREZ

2024-518521-14-00

SEDACIÓN INHALADA EN EL ENFERMO CRÍTICO: ENSAYO CLÍNICO MULTICÉNTRICO Y ALEATORIZADO

IV

YES

NO

MANUEL PEREZ TORRES

NA

INDIVIDUALIZED PERIOPERATIVEOPEN LUNG VENTILATORY APPROACH IN EMERGENCY ABDOMINAL LAPARO-TOMY/SCOPY. A PROSPECTIVE MULTICENTER RANDOMIZED CONTROLLED TRIAL

NA

YES

NO

SOLEDAD BELLAS COTAN

NA

EFECTIVIDAD Y EFICIENCIA DE LOS SISTEMAS DE RETORNO DE SANGRE EN EL PACIENTE CRÍTICO ADULTO: ENSAYO CLÍNICO MULTICÉNTRICO ALEATORIZADO

NA

YES

NO

SONIA LOPEZ CUENCA

MC1: MULTICENTRE INT2: INTERNATIONAL




Patents (revisar)

Title: Obturador rectal para cirugía proctológica.

Application No: U201831943

Main entities: FIIS-FJD (100%)

Inventors: Carlos García Vásquez, Santos Jiménez De Los Galanes Marchán, Pedro Pacheco Martínez.


Title: Sistema configurado para la implantación de un material protésico en pacientes que sufren una patología quirúrgica de la pared abdominal.

Application No: P202130319

Main entities: FIIS-FJD (100%)

Inventors: Carlos García Vásquez; Santos Jiménez de los Galanes Marchán; Pedro Pacheco Martínez.


Title: System configured for the implantation of a prosthetic material in patients suffering from a surgical pathology in the abdominal wall.

Application No: PCT/ES2022/070218

Main entities: FIIS-FJD (100%)

Inventors: Carlos García Vásquez; Santos Jiménez de los Galanes Marchán; Pedro Pacheco Martínez.


Title: Method for estimating the ventricular stroke volume from the pulmonary artery pressure.

Application No: EP23382143.8

Main entities: FIIS-FJD (80%), CIBER (10%), CIC BIOMAGUNE (10%)

Inventors: Arnoldo Santos Oviedo, Jesús María Ruiz-Cabello Osuna.


Intellectual Property Registrations

Title: Proyecto STIQ: Cirugía segura, afectiva y efectiva.

Código identificativo: 08bf4f4120b8d390f4450932402e2ee37f0eaadc45705afd4462ac3c2126a6f1

Centro: HURJC

Autor/es: Lorena Pingarrón y Dolores Martín Ríos.