Cancer

Area coordinator:

• Federico Rojo Todo
  CV de Federico Rojo Todo (61.4 KB ) (3 pages)
  FRojo@fjd.es

Research in the Cancer Area is carried out at three complementary levels: basic research, translational research and clinical research. The Cancer Area is made up of the Pathological Anatomy, Medical Oncology and Haematology groups, as well as two associated groups.

Its objectives include:

• To improve understanding of genetic and protein alterations in solid and haematological malignancies.
• To further investigate the mechanisms underlying resistance to current therapies, with a particular focus on the immune system and the tumour microenvironment, to identify new immunotherapeutic strategies.
• To promote research into the tumour microenvironment through both drug development and clinical trials; to explore new technologies and approaches for its characterisation; and to evaluate strategies aimed at targeting the pro-tumorigenic microenvironment to maximise therapeutic benefit.
• To identify, using prospective samples, tumour cell and immune biomarkers that may help distinguish patients most likely to benefit from next generation therapies.

Is There a Role for Mifamurtide in Nonmetastatic High-Grade Osteosarcoma? Results From the Italian Sarcoma Group (ISG/OS-2) and Spanish Sarcoma Group (GEIS-33) Trials.

Palmerini E, Meazza C, Tamburini A, Márquez-Vega C, Bisogno G, Fagioli F, Ferraresi V, Milano GM, Coccoli L, Rubio-San-Simón A, Gallego O, Llinares Riestra ME, Manzitti C, Mora J, Vaz-Salgado MÁ, Luksch R, Mata C, Pierini M, Carretta E, Cesari M, Paioli A, Marrari A, Scotlandi K, Serra M, Asaftei SD, Gambarotti M, Picci P, Ferrari S, Valverde C, Ibrahim T, Broto JM.

J Clin Oncol. 2025 Oct.43(28):3113-3122.

PMID: 40825172

IF: 43,4

http://dx.doi.org/10.1200/JCO-25-00210

Early-Stage Mycosis Fungoides: Searching for biomarkers associated with advanced stage progression.

Rebollo-González M, Gargallo-Moneva V, Sánchez-Martínez A, Torre-Castro J, Herencia C, Moreno-Delgado M, Alonso-Alonso R, Manso R, Borregón J, Díaz de la Pinta FJ, Pajares R, Gotor-Rivera A, Torres-Navarro I, Morillo-Giles D, Moreno-Vílchez C, Martín-Torregrosa D, Muniesa C, Servitje O, Climent F, Frutos Díaz-Alejo J, Rivera-Díaz R, Ortiz-Romero PL, Rodríguez-Peralto JL, Rodríguez-Pinilla SM, Rodríguez M.

Br J Dermatol. 2025 May 27.

PMID: 40424592

IF: 10,6

http://dx.doi.org/10.1093/bjd/ljaf204

Inflammatory Fibroid Polyp (Vanek's Tumor): A Retrospective Multicentric Analysis of 67 Cases.

Sánchez MM, Domínguez-Prieto V, Qian Zhang S, Quiceno Arias HD, Álvarez Álvarez MB, Fuertes MJ, Meliga C, Jiménez-Galanes S, Labajo HG, Olmo DG, Campos PV.

Cancers (Basel). 2025 Apr 02.17(7).

PMID: 40227778

IF: 4,4

http://dx.doi.org/10.3390/cancers17071209

Diffuse large B-cell lymphoma presenting as acute adrenal hemorrhage.

Torres F, Suárez U, Pizano P.

Blood Res. 2025 Mar 19.60(1):18.

PMID: 40106058

IF: 2,8

http://dx.doi.org/10.1007/s44313-025-00064-8

Epcoritamab plus GemOx in transplant-ineligible relapsed/refractory DLBCL: results from the EPCORE NHL-2 trial.

Brody JD, Jørgensen JM, Belada D, Costello R, Trněný M, Vitolo U, Lewis DJ, Karimi YH, Sureda A, Andre M, Wahlin BE, Lugtenburg PJ, Jiang T, Karagoz K, Steele AJ, Abbas A, Wang L, Risum M, Cordoba R.

Blood. 2025 Jan 10.

PMID: 39792928

IF: 23,1

http://dx.doi.org/10.1182/blood.2024026830

Gender Perspective in the Cancer Area

The Cancer area is made up of a group of professionals committed to respect and equality among its team members, which seeks to promote the professional development of all its personnel without discrimination based on gender or age.

Cáncer-02

Future challenges for the Cancer area

• Development of alternative research models (humanised mice and organoids) to recreate different human tumour models across a broad spectrum of stages of tumorigenesis.
• Development of new high-throughput diagnostic tools (next-generation sequencing and proteomics) and minimally invasive technologies (liquid biopsy and imaging) for cancer, aimed at patient stratification and disease monitoring.

Research groups

• Pathological Anatomy
• Medical Oncology
• Haematology
• General surgery, Thoracic surgery, Neurosurgery and Other surgical specialties
• Radiation Oncology Associated Group