Publicaciones más relevantes

Actualización de datos a 31/12/2025

A continuación se detallan las publicaciones más relevantes de 2025:

• Área de Cáncer.

Is There a Role for Mifamurtide in Nonmetastatic High-Grade Osteosarcoma? Results From the Italian Sarcoma Group (ISG/OS-2) and Spanish Sarcoma Group (GEIS-33) Trials.

Palmerini E, Meazza C, Tamburini A, Márquez-Vega C, Bisogno G, Fagioli F, Ferraresi V, Milano GM, Coccoli L, Rubio-San-Simón A, Gallego O, Llinares Riestra ME, Manzitti C, Mora J, Vaz-Salgado MÁ, Luksch R, Mata C, Pierini M, Carretta E, Cesari M, Paioli A, Marrari A, Scotlandi K, Serra M, Asaftei SD, Gambarotti M, Picci P, Ferrari S, Valverde C, Ibrahim T, Broto JM.

J Clin Oncol. 2025 Oct.43(28):3113-3122.

PMID: 40825172

FI: 43,4

http://dx.doi.org/10.1200/JCO-25-00210

Early-Stage Mycosis Fungoides: Searching for biomarkers associated with advanced stage progression.

Rebollo-González M, Gargallo-Moneva V, Sánchez-Martínez A, Torre-Castro J, Herencia C, Moreno-Delgado M, Alonso-Alonso R, Manso R, Borregón J, Díaz de la Pinta FJ, Pajares R, Gotor-Rivera A, Torres-Navarro I, Morillo-Giles D, Moreno-Vílchez C, Martín-Torregrosa D, Muniesa C, Servitje O, Climent F, Frutos Díaz-Alejo J, Rivera-Díaz R, Ortiz-Romero PL, Rodríguez-Peralto JL, Rodríguez-Pinilla SM, Rodríguez M.

Br J Dermatol. 2025 May 27.

PMID: 40424592

FI: 10,6

http://dx.doi.org/10.1093/bjd/ljaf204

Inflammatory Fibroid Polyp (Vanek's Tumor): A Retrospective Multicentric Analysis of 67 Cases.

Sánchez MM, Domínguez-Prieto V, Qian Zhang S, Quiceno Arias HD, Álvarez Álvarez MB, Fuertes MJ, Meliga C, Jiménez-Galanes S, Labajo HG, Olmo DG, Campos PV.

Cancers (Basel). 2025 Apr 02.17(7).

PMID: 40227778

FI: 4,4

http://dx.doi.org/10.3390/cancers17071209

Diffuse large B-cell lymphoma presenting as acute adrenal hemorrhage.

Torres F, Suárez U, Pizano P.

Blood Res. 2025 Mar 19.60(1):18.

PMID: 40106058

FI: 2,8

http://dx.doi.org/10.1007/s44313-025-00064-8

Epcoritamab plus GemOx in transplant-ineligible relapsed/refractory DLBCL: results from the EPCORE NHL-2 trial.

Brody JD, Jørgensen JM, Belada D, Costello R, Trněný M, Vitolo U, Lewis DJ, Karimi YH, Sureda A, Andre M, Wahlin BE, Lugtenburg PJ, Jiang T, Karagoz K, Steele AJ, Abbas A, Wang L, Risum M, Cordoba R.

Blood. 2025 Jan 10.

PMID: 39792928

FI: 23,1

http://dx.doi.org/10.1182/blood.2024026830

• Área de Enfermedades Infecciosas, Inflamatorias y Crónicas.

Factors associated with failed conservative treatment in patients with degenerative full-thickness supraspinatus tears : a prospective cohort study.

Martinez-Catalan N, Gabardo-Calvo S, Valencia M, Luengo-Alonso G, Delgado C, Foruria AM, Fernandez-Jara J, Calvo E.

Bone Joint J. 2025 Dec 01.107-B(12):1295-1300.

PMID: 41319708

FI: 4,6

http://dx.doi.org/10.1302/0301-620X.107B12.BJJ-2025-0742.R2

Functional cure of HIV-1 infection in an exceptional elite controller: a case report.

Benito JM, Lopez-Bernaldo JC, Fisher K, Pereyra-Casanova A, Cabello A, Estrada V, Gorgolas M, Buzon MJ, Palmer S, Rallón N.

Lancet HIV. 2025 Dec.12(12):e850-e860.

PMID: 41202829

FI: 13

http://dx.doi.org/10.1016/S2352-3018(25)00233-4

Optimized use and performance of culture for periprosthetic joint infection diagnosis: a comprehensive literature review.

Esteban J, Patel R, Aguilera-Correa J-J, Nelson SB, Culture Working Group of the Unified PJI Definition Task Force.

Clin Microbiol Rev. 2025 Dec 11.38(4):e0005425.

PMID: 40965158

FI: 19,3

http://dx.doi.org/10.1128/cmr.00054-25

Role of Inflammasome in IgE-Mediated Anaphylaxis.

Fernandez-Bravo S, Fernandez-Santamaria R.

Allergy. 2025 Oct 25.

PMID: 41137486

FI: 12

http://dx.doi.org/10.1111/all.70123

Sultiame once per day in obstructive sleep apnoea (FLOW): a multicentre, randomised, double-blind, placebo-controlled, dose-finding, phase 2 trial.

Randerath W, Grote L, Stenlöf K, Fietze I, Chevts J, Buntinx E, Albares J, Kuhn K, Hansen C, Völp A, Hedner J, FLOW study investigators (FLOW study investigators: Troncoso-Acevedo F).

Lancet. 2025 Oct 25.406(10514):1983-1992.

PMID: 41077049

FI: 88,5

http://dx.doi.org/10.1016/S0140-6736(25)01196-1

• Área de Neurociencias.

Impact of Digital Safety Plan Activation on Subsequent Emergency Departments Visits Following an Initial Suicide Attempt: Quasi-Experimental Study.

Barrigón ML, Schmidt C, Elices M, Porras-Segovia A, De Granda-Beltrán AM, Artés-Rodríguez A, Courtet P, Pérez-Sola V, Baca-García E.

JMIR Ment Health. 2025 Jun 17.12:e70253.

PMID: 40526825

FI: 5,8

http://dx.doi.org/10.2196/70253

Advancing Risk Assessment in Myotonic Muscular Dystrophy Through Translational Research and Personalized Medicine.

Amarante-Cuadrado C, Vazirani R.

JACC Clin Electrophysiol. 2025 May.11(5):1039.

PMID: 40436470

FI: 7,7

http://dx.doi.org/10.1016/j.jacep.2025.02.045

Prevalence, disability, and economic impact of migraine in Spain: a nationwide population-based study.

Sanchez-Del-Rio M, García-Azorín D, Peral C, Armada B, Irimia-Sieira P, Porta-Etessam J.

J Headache Pain. 2025 May 15.26(1):117.

PMID: 40375151

FI: 7,9

http://dx.doi.org/10.1186/s10194-025-02069-1

Artificial intelligence in healthcare: Revolution or unfulfilled promise?

Anmella G, Baca-García E.

Eur Neuropsychopharmacol. 2025 Feb 15.94:1-3.

PMID: 39956012

FI: 6,7

http://dx.doi.org/10.1016/j.euroneuro.2025.01.006

Decoding the general role of tRNA queuosine modification in eukaryotes.

Díaz-Rullo J, González-Moreno L, Del Arco A, González-Pastor JE.

Sci Rep. 2025 Jan 02.15(1):345.

PMID: 39747999

FI: 3,9

http://dx.doi.org/10.1038/s41598-024-83451-y

• Área de CRM (Enfermedades Cardiovasculares, Renales y Metabólicas).

Excessive glycosylation drives thoracic aortic aneurysm formation through integrated stress response.

Rochano-Ortiz A, San Sebastián-Jaraba I, Zamora C, Simó C, García-Cañas V, Martínez-Albaladejo S, Fernández-Gómez MJ, Marcos-Ríos D, Martínez-Núñez P, Martín-Lorenzo M, Velho TR, Ruíz-Rodríguez MJ, Leal-Zafra A, Gabandé-Rodríguez E, Martínez-Martínez S, Guala A, Lorenzo Ó, Blanco-Colio LM, Martín-Ventura JL, Álvarez-Llamas G, Aldamiz-Echevarría G, Teixidó-Tura G, Forteza A, Nistal JF, Redondo JM, Méndez-Barbero N, Mittelbrunn M, Oller J.

Eur Heart J. 2025 Dec 01.46(45):4988-5005.

PMID: 40720766

FI: 35,7

http://dx.doi.org/10.1093/eurheartj/ehaf556

Beta-Blockers after Myocardial Infarction without Reduced Ejection Fraction.

Ibanez B, Latini R, Rossello X, Dominguez-Rodriguez A, Fernández-Vazquez F, Pelizzoni V, Sánchez PL, Anguita M, Barrabés JA, Raposeiras-Roubín S, Pocock S, Escalera N, Staszewsky L, Pérez-García CN, Díez-Villanueva P, Pérez-Rivera JA, Prada-Delgado O, Owen R, Pizarro G, Caldes O, Gómez-Talavera S, Tuñón J, Bianco M, Zarauza J, Vetrano A, Campos A, Martínez-Huertas S, Bueno H, Puentes M, Grigis G, Bonilla-Palomas JL, Marco E, González-Juanatey JR, Bangueses R, González-Juanatey C, García-Álvarez A, Ruiz-García J, Carrasquer A, García-Rubira JC, Pascual-Figal D, Tomás-Querol C, San Román JA, Baratta P, Agüero J, Martín-Reyes R, Colivicchi F, Ortas-Nadal R, Bazal P, Cordero A, Fernández-Ortiz A, Basso P, González E, Poletti F, Bugani G, Debiasio M, Cosmi D, Navazio A, Bermejo J, Tortorella G, Marini M, Botas J, de la Torre-Hernández JM, Ottani F, Fuster V, REBOOT-CNIC Investigators.

N Engl J Med. 2025 Nov 13.393(19):1889-1900.

PMID: 40888702

FI: 78,5

http://dx.doi.org/10.1056/NEJMoa2504735

Sleep-Wake Cycle and Circadian Misalignment in People With Autism Across the Lifespan With an Emphasis on Living Conditions.

Martínez-Cayuelas E, García-Muñoz AM, de Ocaña-Moreno MLS, Richdale AL, Gisbert-Gustemps L, Lugo-Marín J, Rodríguez-Morillas B, Peiró-Peiró AM, Victoria-Montesinos D, López-Anguas C, Meseguer-Illán MD, Ballester-Navarro P.

Autism Res. 2025 Jun 02.

PMID: 40452585

FI: 5,6

http://dx.doi.org/10.1002/aur.70058

Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990-2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021.

GBD 2021 Adolescent BMI Collaborators (Ortiz A).

Lancet. 2025 Mar 08.405(10481):785-812.

PMID: 40049185

FI: 88,5

http://dx.doi.org/10.1016/S0140-6736(25)00397-6

Evaluation and Analysis of Costs Associated with Prophylaxis of Recurrent Urinary Tract Infections (RUTIs) in Women.

Hernández-Sánchez JE, Szczesnieski JJ, Padilla-Fernández BY, González-Enguita C, Flores-Fraile J, Lorenzo-Gómez MF.

Microorganisms. 2025 Feb 11.13(2).

PMID: 40005759

FI: 4,2

http://dx.doi.org/10.3390/microorganisms13020393

• Área de Genómica y Epidemiología.

CCL18: a potential immunosuppressive biomarker for prognosis in ABC diffuse large B-cell lymphoma.

Rodríguez M, Rojas-Vega F, Díaz-Alejo JF, Mahillo-Fernández I, Serrano C, López A, Morales-Ruiz T, Roldan-Arjona T, Sánchez-García J, Río-Machín A, Morillo D, Pérez MA, Córdoba R, Llamas-Sillero P, Rodríguez-Pinilla SM, Serrano-López J.

Front Immunol. 2025.16:1693730.

PMID: 41472741

FI: 5,9

http://dx.doi.org/10.3389/fimmu.2025.1693730

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK pathways.

Marco-Bonilla M, Fresnadillo M, Sanchez-Platero I, de la Riva-Bueno M, Huete-Toral F, Carracedo G, Conde C, Benitez Y, Minguez P, Cifuentes SC, Rams J, Herrero-Beaumont G, Largo R, Mediero A.

Arthritis Rheumatol. 2025 Dec 29.

PMID: 41466573

FI: 10,9

http://dx.doi.org/10.1002/art.70047

SARS-CoV-2 mutant spectrum complexity is an epidemiologically evolvable trait.

Martínez-González B, Soria ME, de Ávila AI, Somovilla P, Aguilar-Sabido C, Mínguez P, Ferrer-Orta C, Salar-Vidal L, Lorenzo-Redondo R, Delgado S, Morán F, Verdaguer N, Gadea I, Domingo E, Perales C.

Proc Natl Acad Sci U S A. 2025 Sep 30.122(39):e2515706122.

PMID: 40991435

FI: 9,1

http://dx.doi.org/10.1073/pnas.2515706122

Long-Read Whole-Genome Sequencing as a Tool for Variant Detection in Inherited Retinal Dystrophies.

Rodilla C, Núñez-Moreno G, Benitez Y, Rodríguez de Alba M, Blanco-Kelly F, López-Alcojor A, Fernández-Caballero L, Perea-Romero I, Del Pozo-Valero M, García-García G, Balanzá M, Villaverde C, Zurita O, Jubin C, Fund C, Delepine M, Leduc A, Deleuze JF, Millán JM, Minguez P, Corton M, Ayuso C.

Int J Mol Sci. 2025 Apr 18.26(8).

PMID: 40332496

FI: 4,9

http://dx.doi.org/10.3390/ijms26083825

Bi-allelic variants in three genes encoding distinct subunits of the vesicular AP-5 complex cause hereditary macular dystrophy.

Kaminska K, Cancellieri F, Quinodoz M, Moye AR, Bauwens M, Lin S, Janeschitz-Kriegl L, Hayman T, Barberán-Martínez P, Schlaeger R, Van den Broeck F, Ávila Fernández A, Fernández-Caballero L, Perea-Romero I, García-García G, Salom D, Mazzola P, Zuleger T, Poths K, Haack TB, Jacob J, Vermeer S, Terbeek F, Feltgen N, Moulin AP, Koutroumanou L, Papadakis G, Browning AC, Madhusudhan S, Gränse L, Banin E, Sousa AB, Coutinho Santos L, Kuehlewein L, De Angeli P, Leroy BP, Mahroo OA, Sedgwick F, Eden J, Pfau M, Andréasson S, Scholl HPN, Ayuso C, Millán JM, Sharon D, Tsilimbaris MK, Vaclavik V, Tran HV, Ben-Yosef T, De Baere E, Webster AR, Arno G, Sergouniotis PI, Kohl S, Santos C, Rivolta C.

Am J Hum Genet. 2025 Apr 03.112(4):808-828.

PMID: 40081374

FI: 8,1

http://dx.doi.org/10.1016/j.ajhg.2025.02.015

• Área de Tecnología e Innovación Sanitaria.