Publicaciones más relevantes

A continuación se detallan las publicaciones más relevantes de 2021:

• Área de Cáncer.

Randomized Phase III Trial of Prophylactic Cranial Irradiation With or Without Hippocampal Avoidance for Small-Cell Lung Cancer (PREMER): A GICOR-GOECP-SEOR Study.

Rodríguez de Dios N, Couñago F, Murcia-Mejía M, Rico-Oses M, Calvo-Crespo P, Samper P, Vallejo C, Luna J, Trueba I, Sotoca A, Cigarral C, Farré N, Manero RM, Durán X, Gispert JD, Sánchez-Benavides G, Rognoni T, Torrente M, Capellades J, Jiménez M, Cabada T, Blanco M, Alonso A, Martínez-San Millán J, Escribano J, González B, López-Guerra JL

Journal of clinical oncology. Epub 2021 Aug 11. 2021 Oct 1;39(28):3118-3127.

PMID: 34379442

FI: 44,544

Advances in Management for Older Adults With Hematologic Malignancies.

Rosko AE, Cordoba R, Abel G, Artz A, Loh KP, Klepin HD

Journal of clinical oncology. Epub 2021 May 27. 2021 Jul 1;39(19):2102-2114.

PMID: 34043442

FI: 44,544

Five-Year Outcomes From the Randomized, Phase III Trials CheckMate 017 and 057: Nivolumab Versus Docetaxel in Previously Treated Non-Small-Cell Lung Cancer.

Borghaei H, Gettinger S, Vokes EE, Chow LQM, Burgio MA, de Castro Carpeno J, Pluzanski A, Arrieta O, Frontera OA, Chiari R, Butts C, Wójcik-Tomaszewska J, Coudert B, Garassino MC, Ready N, Felip E, García MA, Waterhouse D, Domine M, Barlesi F, Antonia S, Wohlleber M, Gerber DE, Czyzewicz G, Spigel DR, Crino L, Eberhardt WEE, Li A, Marimuthu S, Brahmer J

Journal of clinical oncology. Epub 2021 Jan 15. 2021 Mar 1;39(7):723-733.

PMID: 33449799

FI: 44,544

Pancytopenia, needles, and parasites.

Suarez, EU; de Ozaeta, CS

BMJ-British Medical Journal. 2021 Oct 13;375:n2087.

PMID:

FI: 39,89

SPARC macrophages in lymphoma.

Piris MA

Annals of oncology. Epub 2021 Sep 4. 2021 Nov;32(11):1314-1315.

PMID: 34492312

FI: 32,976

• Área de Enfermedades Infecciosas, Inflamatorias y Crónicas.

Effect of a Pulmonary Embolism Diagnostic Strategy on Clinical Outcomes in Patients Hospitalized for COPD Exacerbation: A Randomized Clinical Trial.

Jiménez D, Agustí A, Tabernero E, Jara-Palomares L, Hernando A, Ruiz-Artacho P, Pérez-Peñate G, Rivas-Guerrero A, Rodríguez-Nieto MJ, Ballaz A, Agüero R, Jiménez S, Calle-Rubio M, López-Reyes R, Marcos-Rodríguez P, Barrios D, Rodríguez C, Muriel A, Bertoletti L, Couturaud F, Huisman M, Lobo JL, Yusen RD, Bikdeli B, Monreal M, Otero R, SLICE Trial Group.

JAMA. 2021 Oct 5;326(13):1277-1285.

PMID: 34609451

FI: 56,274

Identification and validation of clinical phenotypes with prognostic implications in patients admitted to hospital with COVID-19: a multicentre cohort study.

Gutiérrez-Gutiérrez B, Del Toro MD, Borobia AM, Carcas A, Jarrín I, Yllescas M, Ryan P, Pachón J, Carratalà J, Berenguer J, Arribas JR, Rodríguez-Baño J, REIPI-SEIMC COVID-19 group and COVID@HULP groups. (Cabello A, Carrasco-Anton N, Álvarez B, Petkova E, Gorgolas M, Prieto-Pérez L, Carrillo I, Heili Frades S, Villar-Álvarez F, Fernandez-Roblas R, Sánchez-Pernaute O)

The Lancet. Infectious diseases. Epub 2021 Feb 23. 2021 Jun;21(6):783-792.

PMID: 33636145

FI: 25,071

EULAR recommendations for intra-articular therapies.

Uson J, Rodriguez-García SC, Castellanos-Moreira R, O'Neill TW, Doherty M, Boesen M, Pandit H, Möller Parera I, Vardanyan V, Terslev L, Kampen WU, D'Agostino MA, Berenbaum F, Nikiphorou E, Pitsillidou IA, de la Torre-Aboki J, Carmona L, Naredo E

Annals of the rheumatic diseases. 2021 May 25;annrheumdis-2021-220266.

PMID: 34035002

FI: 19,103

Proteomic profile of extracellular vesicles in anaphylaxis and their role in vascular permeability.

Nuñez-Borque E, Fernandez-Bravo S, Pastor-Vargas C, Alvarez-Llamas G, Gutierrez-Blazquez MD, Alwashali E, Laguna JJ, Dionicio J, Betancor D, Villalobos V, Tome-Amat J, Cuesta-Herranz J, Benito-Martin A, Esteban V

Allergy. Epub 2021 Mar 20. 2021 Jul;76(7):2276-2279.

PMID: 33629411

FI: 13,146

Historical Perspective on the Discovery of the Quasispecies Concept.

Domingo E, García-Crespo C, Perales C

Annual review of virology. 2021 Sep 29;8(1):51-72.

PMID: 34586874

FI: 10,431

• Área de Neurociencias.

4-Aminopyridine is a promising treatment option for patients with gain-of-function KCNA2-encephalopathy.

Hedrich UBS, Lauxmann S, Wolff M, Synofzik M, Bast T, Binelli A, Serratosa JM, Martínez-Ulloa P, Allen NM, King MD, Gorman KM, Zeev BB, Tzadok M, Wong-Kisiel L, Marjanovic D, Rubboli G, Sisodiya SM, Lutz F, Ashraf HP, Torge K, Yan P, Bosselmann C, Schwarz N, Fudali M, Lerche H

Science translational medicine. 2021 Sep;13(609):eaaz4957.

PMID: 34516822

FI: 17,992

Blood-brain barrier opening with focused ultrasound in Parkinson's disease dementia.

Gasca-Salas C, Fernández-Rodríguez B, Pineda-Pardo JA, Rodríguez-Rojas R, Obeso I, Hernández-Fernández F, Del Álamo M, Mata D, Guida P, Ordás-Bandera C, Montero-Roblas JI, Martínez-Fernández R, Foffani G, Rachmilevitch I, Obeso JA

Nature communications. 2021 Feb 3;12(1):779.

PMID: 33536430

FI: 14,919

Decision-making in suicidal behavior: A systematic review and meta-analysis.

Sastre-Buades A, Alacreu-Crespo A, Courtet P, Baca-Garcia E, Barrigon ML

Neuroscience and biobehavioral reviews. Epub 2021 Oct 5. 2021 Dec;131:642-662.

PMID: 34619171

FI: 8,989

Generation of mitochondrial reactive oxygen species is controlled by ATPase inhibitory factor 1 and regulates cognition.

Esparza-Moltó PB, Romero-Carramiñana I, Núñez de Arenas C, Pereira MP, Blanco N, Pardo B, Bates GR, Sánchez-Castillo C, Artuch R, Murphy MP, Esteban JA, Cuezva JM.

PLoS biology. 2021 May 13;19(5):e3001252.

PMID: 33983919

FI: 8,029

Left anterior right temporal position and ultra-brief pulse stimulus in the management of ECT-induced mania.

Abascal-Peiró S, Barrigón ML, Baca-García E, Ovejero S

Bipolar disorders. Epub 2021 Nov 16. 2022 Feb;24(1):97-100.

PMID: 34714603

FI: 6,744

• Área de Enfermedades Renales, Metabólicas y Cardiovasculares.

A Novel Circulating MicroRNA for the Detection of Acute Myocarditis.

Blanco-Domínguez R, Sánchez-Díaz R, de la Fuente H, Jiménez-Borreguero LJ, Matesanz-Marín A, Relaño M, Jiménez-Alejandre R, Linillos-Pradillo B, Tsilingiri K, Martín-Mariscal ML, Alonso-Herranz L, Moreno G, Martín-Asenjo R, García-Guimaraes MM, Bruno KA, Dauden E, González-Álvaro I, Villar-Guimerans LM, Martínez-León A, Salvador-Garicano AM, Michelhaugh SA, Ibrahim NE, Januzzi JL, Kottwitz J, Iliceto S, Plebani M, Basso C, Baritussio A, Seguso M, Marcolongo R, Ricote M, Fairweather D, Bueno H, Fernández-Friera L, Alfonso F, Caforio ALP, Pascual-Figal DA, Heidecker B, Lüscher TF, Das S, Fuster V, Ibáñez B, Sánchez-Madrid F, Martín P

The New England journal of medicine. 2021 May 27;384(21):2014-2027.

PMID: 34042389

FI: 91,253

Belimumab in Lupus Nephritis.

Rojas-Rivera J, Ortiz A, Carriazo S

The New England journal of medicine. 2021 Jan 14;384(2):187.

PMID: 33497557

FI: 91,253

Good night, sleep tight.

García-Lunar I, Fuster V, Ibanez B

European heart journal. 2021 Jun 1;42(21):2100-2102.

PMID: 33876210

FI: 29,983

Lipoprotein(a), LDL-cholesterol, and hypertension: predictors of the need for aortic valve replacement in familial hypercholesterolaemia.

Pérez de Isla L, Watts GF, Alonso R, Díaz-Díaz JL, Muñiz-Grijalvo O, Zambón D, Fuentes F, de Andrés R, Padró T, López-Miranda J, Mata P

European heart journal. 2021 Jun 7;42(22):2201-2211.

PMID: 33437997

FI: 29,983

Extracellular Tuning of Mitochondrial Respiration Leads to Aortic Aneurysm.

Oller J, Gabandé-Rodríguez E, Ruiz-Rodríguez MJ, Desdín-Micó G, Aranda JF, Rodrigues-Diez R, Ballesteros-Martínez C, Blanco EM, Roldan-Montero R, Acuña P, Forteza Gil A, Martín-López CE, Nistal JF, Lino Cardenas CL, Lindsay ME, Martín-Ventura JL, Briones AM, Miguel Redondo J, Mittelbrunn M

Circulation. 2021 May 25;143(21):2091-2109.

PMID: 33709773

FI: 29,69

• Área de Genética y Genómica.

Neptune: an environment for the delivery of genomic medicine.

Eric V, Yi V, Murdock D, Kalla SE, Wu TJ, Sabo A, Li S, Meng Q, Tian X, Murugan M, Cohen M, Kovar C, Wei WQ, Chung WK, Weng C, Wiesner GL, Jarvik GP, Muzny D, Gibbs RA, eMERGE Consortium. (Almoguera B)

Genetics in medicine. Epub 2021 Jul 13. 2021 Oct;23(10):1838-1846.

PMID: 34257418

FI: 8,822

Comparison of the diagnostic yield of aCGH and genome-wide sequencing across different neurodevelopmental disorders.

Martinez-Granero F, Blanco-Kelly F, Sanchez-Jimeno C, Avila-Fernandez A, Arteche A, Bustamante-Aragones A, Rodilla C, Rodríguez-Pinilla E, Riveiro-Alvarez R, Tahsin-Swafiri S, Trujillo-Tiebas MJ, Ayuso C, Rodríguez de Alba M, Lorda-Sanchez I, Almoguera B

NPJ genomic medicine. 2021 Mar 25;6(1):25.

PMID: 33767182

FI: 8,617

Prioritizing variants of uncertain significance for reclassification using a rule-based algorithm in inherited retinal dystrophies.

Iancu IF, Avila-Fernandez A, Arteche A, Trujillo-Tiebas MJ, Riveiro-Alvarez R, Almoguera B, Martin-Merida I, Del Pozo-Valero M, Perea-Romero I, Corton M, Minguez P, Ayuso C

NPJ genomic medicine. 2021 Feb 23;6(1):18.

PMID: 33623043

FI: 8,617

Risk of pre-eclampsia in patients with a maternal genetic predisposition to common medical conditions: a case-control study.

Gray KJ, Kovacheva VP, Mirzakhani H, Bjonnes AC, Almoguera B, Wilson ML, Ingles SA, Lockwood CJ, Hakonarson H, McElrath TF, Murray JC, Norwitz ER, Karumanchi SA, Bateman BT, Keating BJ, Saxena R

BJOG : an international journal of obstetrics and gynaecology. 2021 Jan;128(1):55-65.

PMID: 32741103

FI: 6,531

The UpPriority tool supported prioritization processes for updating clinical guideline questions.

Sanabria AJ, Alonso-Coello P, McFarlane E, Niño de Guzman E, Roqué M, Martínez García L, UpPriority Implementation Working Group. (Ayuso C)

Journal of clinical epidemiology. Epub 2021 Aug 5. 2021 Nov;139:149-159.

PMID: 34363971

FI: 6,437

Gene Correction Recovers Phagocytosis in Retinal Pigment Epithelium Derived from Retinitis Pigmentosa-Human-Induced Pluripotent Stem Cells.

Artero-Castro A, Long K, Bassett A, Ávila-Fernandez A, Cortón M, Vidal-Puig A, Jendelova P, Rodriguez-Jimenez FJ, Clemente E, Ayuso C, Slaven E

International journal of molecular sciences. 2021 Feb 20;22(4):2092.

PMID: 33672445

FI: 5,924

• Área de Tecnología e Innovación Sanitaria.