Actualización de datos a 31/12/2024


A continuación se detallan las publicaciones más relevantes de 2024:

  • Área de Cáncer.

Preclinical development of three novel CARs targeting CD79b for the treatment of non-Hodgkin's lymphoma and characterization of the loss of the target antigen.

Esquinas E, Moreno-Sanz A, Sandá V, Stodulski-Ciesla D, Borregón J, Peña-Blanque V, Fernández-Calles J, Fernandez-Fuentes N, Serrano-Lopez J, Juan M, Engel P, Llamas-Sillero P, Solán-Blanco L, Martin-Antonio B.

J Immunother Cancer. 2024 Dec 18.12(12).

PMID: 39694704

FI: 10,3


Phase Ib Study for the Combination of Doxorubicin, Dacarbazine, and Nivolumab as the Upfront Treatment in Patients With Advanced Leiomyosarcoma: A Study by the Spanish Sarcoma Group (GEIS).

Martin-Broto J, Diaz-Beveridge R, Moura D, Ramos R, Martinez-Trufero J, Carrasco I, Sebio A, González-Billalabeitia E, Gutierrez A, Fernandez-Jara J, Hernández-Vargas L, Cruz J, Valverde C, Hindi N.

J Clin Oncol. 2024 Oct 02:JCO2400358.

PMID: 39356980

FI: 42,1


Facts and Hopes in the Systemic Therapy of Biliary Tract Carcinomas.

Lamarca A, Macarulla T.

Clin Cancer Res. 2024 Sep 03.30(17):3688-3696.

PMID: 38934628

FI: 10,4


Mutational profiling of Primary Cutaneous CD4+ Small/Medium T-Cell Lymphoproliferative Disorders do not resemble nodal peripheral T-cell lymphomas with follicular helper T-cell phenotype.

Rodríguez M, Rebollo-González M, Frutos Díaz-Alejo J, Manso R, Díaz de la Pinta FJ, Torre-Castro J, Rodríguez-Pinilla SM.

Br J Dermatol. 2024 May 13.

PMID: 38739743

FI: 11


LT and SOX9 expression are associated with gene sets that distinguish Merkel cell polyomavirus-positive and -negative Merkel cell carcinoma.

Torre-Castro J, Rodríguez M, Alonso-Alonso R, Mendoza Cembranos MD, Frutos Díaz-Alejo J, Rebollo-González M, Borregón J, Nájera Botello L, Mahillo-Fernández I, Samimi M, Kervarrec T, Requena L, Ángel Piris M.

Br J Dermatol. 2024 Jan 23.

PMID: 38261397

FI: 11


  • Área de Enfermedades Infecciosas, Inflamatorias y Crónicas.

Characterization of articular lesions associated with glenohumeral instability using arthroscopy.

Luengo-Alonso G, Valencia M, Martinez-Catalan N, Delgado C, Calvo E.

Bone Joint J. 2024 Oct 01.106-B(10):1125-1132.

PMID: 39348905

FI: 4,9


Validation and incorporation of digital entheses into a preliminary GLobal OMERACT Ultrasound DActylitis Score (GLOUDAS) in psoriatic arthritis.

Naredo E, D'Agostino MA, Terslev L, Pineda C, Miguel MI, Blasi J, Bruyn GA, Kortekaas MC, Mandl P, Nestorova R, Szkudlarek M, Todorov P, Vlad V, Wong P, Bakewell C, Filippucci E, Zabotti A, Micu M, Vreju F, Mortada M, Mendonça JA, Guillen-Astete CA, Olivas-Vergara O, Iagnocco A, Hanova P, Tinazzi I, Balint PV, Aydin SZ, Kane D, Keen H, Kaeley GS, Möller I.

Ann Rheum Dis. 2024 Jul 15.83(8):1060-1071.

PMID: 38531611

FI: 20,3


Single-cell RNA sequencing of human blood eosinophils reveals plasticity and absence of canonical cell subsets.

Rodrigo-Muñoz JM, Naharro-González S, Callejas S, Relaño-Ruperez C, Torroja C, Benguria A, Lorente-Sorolla C, Gil-Martínez M, García de Castro Z, Cañas JA, Valverde-Monge M, Bernaola J, Pinillos-Robles EJ, Betancor D, Fernández-Nieto M, Dopazo A, Sánchez-Cabo F, Sánchez-Pernaute O, Rodríguez-Nieto MJ, Sastre J, Del Pozo V.

Allergy. 2024 Jun 27.

PMID: 38934897

FI: 12,6


Organizing Pneumonia Secondary to ASIA Syndrome.

Piñero-Gutiérrez P, Villar-Álvarez F, Asensio-Mathews P, González-Peinado D.

Arch Bronconeumol. 2024 Jun 06.

PMID: 38906716

FI: 8,7


A specific natural killer cells phenotypic signature associated to long term elite control of HIV infection.

Rallón N, Jiménez-Carretero D, Restrepo C, Ligos JM, Valentín-Quiroga J, Mahillo I, Cabello A, López-Collazo E, Sánchez-Cabo F, Górgolas M, Estrada V, Benito JM, ECRIS integrated in the Spanish AIDS Research Network.

J Med Virol. 2024 May.96(5):e29646.

PMID: 38699988

FI: 6,8


  • Área de Neurociencias.

Plasma Neurodegenerative Biomarkers in Cognitively Preserved Nonagenarians.

Gómez-Tortosa E, Agüero-Rabes P, Ruiz-González A, Wagner S, Téllez R, Mahillo I, Ruiz-Calvo A, Sainz MJ, Nystrom AL, Cremades-Jimeno L, Del Ser T, Sánchez-Juan P.

Aging Dis. 2024 Nov 06.

PMID: 39571163

FI: 7


Emergency psychiatric care for children and adolescents: factors associated with multiple visits and hospital admissions.

Ezquerra B, Peñuelas-Calvo I, Marti-Estevez I, Taracena-Cuerda M, Baca-García E, Porras-Segovia A.

Eur Child Adolesc Psychiatry. 2024 Nov 07.

PMID: 39508852

FI: 6


Gene therapy for Lafora disease in the Epm2a-/- mouse model.

Zafra-Puerta L, Iglesias-Cabeza N, Burgos DF, Sciaccaluga M, González-Fernández J, Bellingacci L, Canonichesi J, Sánchez-Martín G, Costa C, Sánchez MP, Serratosa JM.

Mol Ther. 2024 Jul 03.32(7):2130-2149.

PMID: 38796707

FI: 12,1


Neuronal hypoglycolysis sustains body health.

Pardo B.

Nat Metab. 2024 Jul.6(7):1197-1199.

PMID: 38789797

FI: 19,2


Suicidal behavior: Not just an epiphenomenon of psychiatric illness.

Oquendo MA, Baca-Garcia E.

Eur Neuropsychopharmacol. 2024 Apr.81:41-42.

PMID: 38324939

FI: 6,1


  • Área de Enfermedades Renales, Metabólicas y Cardiovasculares.

Hyperventilation as a Somatoform Respiratory Disorder in Adolescents.

Caballero Fedriani L, Martínez-Cayuelas E, Del-Río Camacho G.

Arch Bronconeumol. 2024 Dec 17.

PMID: 39741041

FI: 8,7


Role of mitochondria in reno-cardiac diseases: A study of bioenergetics, biogenesis, and GSH signaling in disease transition.

Lumpuy-Castillo J, Amador-Martínez I, Díaz-Rojas M, Lorenzo O, Pedraza-Chaverri J, Sánchez-Lozada LG, Aparicio-Trejo OE.

Redox Biol. 2024 Oct.76:103340.

PMID: 39250857

FI: 10,7


Paricalcitol Has a Potent Anti-Inflammatory Effect in Rat Endothelial Denudation-Induced Intimal Hyperplasia.

Baeza C, Pintor-Chocano A, Carrasco S, Sanz A, Ortiz A, Sanchez-Niño MD.

Int J Mol Sci. 2024 Apr 28.25(9).

PMID: 38732029

FI: 4,9


The '10 commandments' for the 2023 ESC Guidelines for the management of acute coronary syndromes.

Byrne R, Coughlan JJ, Rossello X, Ibanez B.

Eur Heart J. 2024 Apr 07.45(14):1193-1195.

PMID: 38206306

FI: 38,1


Versican accumulation drives Nos2 induction and aortic disease in Marfan syndrome via Akt activation.

Ruiz-Rodríguez MJ, Oller J, Martínez-Martínez S, Alarcón-Ruiz I, Toral M, Sun Y, Colmenar Á, Méndez-Olivares MJ, López-Maderuelo D, Kern CB, Nistal JF, Evangelista A, Teixido-Tura G, Campanero MR, Redondo JM.

EMBO Mol Med. 2024 Jan.16(1):132-157.

PMID: 38177536

FI: 9


  • Área de Genética y Genómica.

Cas9-targeted-based long-read sequencing for genetic screening of RPE65 locus.

Rodilla C, Núñez-Moreno G, Benitez Y, Romero R, Fernández-Caballero L, Mínguez P, Corton M, Ayuso C.

Front Genet. 2024.15:1439153.

PMID: 39469149

FI: 2,8


PIM1 is a potential therapeutic target for the leukemogenic effects mediated by JAK/STAT pathway mutations in T-ALL/LBL.

Lahera A, Vela-Martín L, Fernández-Navarro P, Llamas P, López-Lorenzo JL, Cornago J, Santos J, Fernández-Piqueras J, Villa-Morales M.

NPJ Precis Oncol. 2024 Jul 20.8(1):152.

PMID: 39033228

FI: 6,8


Multicentric Longitudinal Prospective Study in a European Cohort of MYO7A Patients: Disease Course and Implications for Gene Therapy.

Testa F, Carreño E, van den Born LI, Melillo P, Perea-Romero I, Di Iorio V, Risca G, Iodice CM, Pennings RJE, Karali M, Banfi S, Auricchio A, Galimberti S, Ayuso C, Simonelli F.

Invest Ophthalmol Vis Sci. 2024 Jun 03.65(6):25.

PMID: 38884554

FI: 5


PRPH2-Related Retinal Dystrophies: Mutational Spectrum in 103 Families from a Spanish Cohort.

Fernández-Caballero L, Martín-Merida I, Blanco-Kelly F, Avila-Fernandez A, Carreño E, Fernandez-San Jose P, Irigoyen C, Jimenez-Rolando B, Lopez-Grondona F, Mahillo I, Martin-Gutierrez MP, Minguez P, Perea-Romero I, Del Pozo-Valero M, Riveiro-Alvarez R, Rodilla C, Rodriguez-Peña L, Sánchez-Barbero AI, Swafiri ST, Trujillo-Tiebas MJ, Zurita O, García-Sandoval B, Corton M, Ayuso C.

Int J Mol Sci. 2024 Mar 02.25(5).

PMID: 38474159

FI: 4,9


Apolipoprotein E-ε2 and Resistance to Atherosclerosis in Midlife: The PESA Observational Study.

Toribio-Fernández R, Tristão-Pereira C, Carlos Silla-Castro J, Callejas S, Oliva B, Fernandez-Nueda I, Garcia-Lunar I, Perez-Herreras C, María Ordovás J, Martin P, Blanco-Kelly F, Ayuso C, Lara-Pezzi E, Fernandez-Ortiz A, Garcia-Alvarez A, Dopazo A, Sanchez-Cabo F, Ibanez B, Cortes-Canteli M, Fuster V.

Circ Res. 2024 Feb 16.134(4):411-424.

PMID: 38258600

FI: 16,5


  • Área de Tecnología e Innovación Sanitaria.

Haematopoietic gene therapy of non-conditioned patients with Fanconi anaemia-A: results from open-label phase 1/2 (FANCOLEN-1) and long-term clinical trials.

Río P, Zubicaray J, Navarro S, Gálvez E, Sánchez-Domínguez R, Nicoletti E, Sebastián E, Rothe M, Pujol R, Bogliolo M, John-Neek P, Bastone AL, Schambach A, Wang W, Schmidt M, Larcher L, Segovia JC, Yáñez RM, Alberquilla O, Díez B, Fernández-García M, García-García L, Ramírez M, Galy A, Lefrere F, Cavazzana M, Leblanc T, García de Andoin N, López-Almaraz R, Catalá A, Barquinero J, Rodríguez-Perales S, Rao G, Surrallés J, Soulier J, Díaz-de-Heredia C, Schwartz JD, Sevilla J, Bueren JA, FANCOLEN-1 gene therapy investigators.

Lancet. 2025 Dec 21.404(10471):2584-2592.

PMID: 39642902

FI: 98,4


Open Up the Lung and Keep the Lung Vessels Open.

Santos A, Ioan AM, Monge MI, Suarez-Sipmann F.

Am J Respir Crit Care Med. 2024 Nov 20.

PMID: 39566067

FI: 19,3


Navigating US participant data sharing requirements: implications for international clinical trials.

Dal-Ré R, Bekker LG, Jha V, Le Louarn A, Naudet F.

BMJ. 2024 Sep 06.386:e079701.

PMID: 39242115

FI: 93,7


Breast cancer survivors suffering from lymphedema: What really do affect to corporeality/body image? A qualitative study.

González-Fernández L, Romero-Morales C, Martínez-Pascual B, Río-González A, Cerezo-Téllez E, López-Martín I.

Breast Cancer Res. 2024 Mar 14.26(1):47.

PMID: 38486203

FI: 6,1


Efficient Generation of Skin Organoids from Pluripotent Cells via Defined Extracellular Matrix Cues and Morphogen Gradients in a Spindle-Shaped Microfluidic Device.

Quílez C, Jeon EY, Pappalardo A, Pathak P, Abaci HE.

Adv Healthc Mater. 2024 Mar 07:e2400405.

PMID: 38452278

FI: 10