Publicaciones más relevantes

A continuación se detallan las publicaciones más relevantes de 2022:

• Área de Cáncer.

Comparison of two chemotherapy regimens in patients with newly diagnosed Ewing sarcoma (EE2012): an open-label, randomised, phase 3 trial.

Brennan B, Kirton L, Marec-Bérard P, Gaspar N, Laurence V, Martín-Broto J, Sastre A, Gelderblom H, Owens C, Fenwick N, Strauss S, Moroz V, Whelan J, Wheatley K.

Lancet. 2022 Oct 29.400(10362):1513-1521.

PMID: 36522207

FI: 202,731

Molecular profiling and precision medicine in rare gastrointestinal cancers within EURACAN in the SPECTA Arcagen study (EORTC-1843): too few patients with matched treatment in Europe.

Lamarca A, Morfouace M, Tejpar S, Oliveira J, Capela A, Penel N, Gennigens C, Brasiuniene B, Peron J, Stevovic A, Blay JY, Klümpen HJ.

Ann Oncol. 2022 Aug 01.

PMID: 35926814

FI: 51,769

Oncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma.

Gállego Pérez-Larraya J, Garcia-Moure M, Labiano S, Patiño-García A, Dobbs J, Gonzalez-Huarriz M, Zalacain M, Marrodan L, Martinez-Velez N, Puigdelloses M, Laspidea V, Astigarraga I, Lopez-Ibor B, Cruz O, Oscoz Lizarbe M, Hervas-Stubbs S, Alkorta-Aranburu G, Tamayo I, Tavira B, Hernandez-Alcoceba R, Jones C, Dharmadhikari G, Ruiz-Moreno C, Stunnenberg H, Hulleman E, van der Lugt J, Idoate MÁ, Diez-Valle R, Esparragosa Vázquez I, Villalba M, de Andrea C, Núñez-Córdoba JM, Ewald B, Robbins J, Fueyo J, Gomez-Manzano C, Lang FF, Tejada S, Alonso MM.

N Engl J Med. 2022 06 30.386(26):2471-2481.

PMID: 35767439

FI: 176,082

Activity and safety of topical pimecrolimus in patients with early stage mycosis fungoides (PimTo-MF): a single-arm, multicentre, phase 2 trial.

Ortiz-Romero PL, Maroñas Jiménez L, Muniesa C, Estrach T, Servitje O, Fernández-de-Misa R, Gallardo F, Sanmartín O, Riveiro-Falkenbach E, García-Díaz N, Vega R, Lora D, Postigo C, Jiménez B, Sánchez-Beato M, Pedro Vaqué J, Rodríguez Peralto JL, de la Cámara AG, de la Cruz J, Piris Pinilla MÁ.

Lancet Haematol. 2022 Jun.9(6):e425-e433.

PMID: 35654076

FI: 30,153

Identification of seasonal variation in the diagnosis of acute myeloid leukaemia: a population-based study.

Sánchez-Vizcaíno F, Tamayo C, Ramos F, Láinez-González D, Serrano-López J, Barba R, Martin MD, Llamas P, Alonso-Dominguez JM.

Br J Haematol. 2022 May 31.

PMID: 35639095

FI: 8,615

• Área de Enfermedades Infecciosas, Inflamatorias y Crónicas.

CPAP Effect on Albuminuria Progression in Patients with Obstructive Sleep Apnea and Diabetic Kidney Disease. A Randomized Clinical Trial.

Zamarrón E, Jaureguizar A, García-Sánchez A, Díaz-Cambriles T, Alonso-Fernández A, Lores V, Mediano O, Troncoso-Acevedo F, Cabello-Pelegrín S, Morales-Ruíz E, Ramírez-Prieto MT, Valiente-Díaz MI, Gómez-García T, Casitas R, Martínez-Cerón E, Galera R, Cubillos-Zapata C, García-Río F; DIANA investigators.

Am J Respir Crit Care Med. 2022 Nov 07.

PMID: 36342964

FI: 30,528

Personalized diagnostic approach and indirect quantification of extravasation in human anaphylaxis.

Nuñez-Borque E, Betancor D, Pastor-Vargas C, Fernández-Bravo S, Martin-Blazquez A, Casado-Navarro N, López-Domínguez D, Gómez-López A, Rodriguez Del Rio P, Tramón P, Beitia JM, Moreno-Aguilar C, González-de-Olano D, Goikoetxea MJ, Ibáñez-Sandín MD, Laguna JJ, Cuesta-Herranz J, Esteban V.

Allergy. 2022 Jul 16.

PMID: 35841381

FI: 14,71

6-Shogaol (enexasogoal) treatment improves experimental knee osteoarthritis exerting a pleiotropic effect over immune innate signalling responses in chondrocytes.

Gratal P, Mediero A, Lamuedra A, Matamoros-Recio A, Herencia C, Herrero-Beaumont G, Martín-Santamaría S, Largo R.

Br J Pharmacol. 2022 Jun 27.

PMID: 35760458

FI: 9,473

Vaccine breakthrough infections with SARS-CoV-2 Alpha mirror mutations in Delta Plus, Iota, and Omicron.

Martínez-González B, Vázquez-Sirvent L, Soria ME, Mínguez P, Salar-Vidal L, García-Crespo C, Gallego I, de Ávila AI, Llorens C, Soriano B, Ramos-Ruiz R, Esteban J, Fernandez-Roblas R, Gadea I, Ayuso C, Ruíz-Hornillos J, Pérez-Jorge C, Domingo E, Perales C.

J Clin Invest. 2022 May 02.132(9).

PMID: 35259127

FI: 19,477

Extracellular Vesicles as a New Promising Therapy in HIV Infection.

Navarrete-Muñoz MA, Llorens C, Benito JM, Rallón N.

Front Immunol. Epub 04 Jan 2022. 2021.12:811471.

PMID: 35058938

FI: 8,787

• Área de Neurociencias.

TRIM25 mutation (p.C168*), coding for an E3 ubiquitin ligase, is a cause of early-onset autosomal dominant dementia with amyloid load and parkinsonism.

Gómez-Tortosa E, Baradaran-Heravi Y, Dillen L, Choudhury NR, Agüero Rabes P, Pérez-Pérez J, Kocoglu C, Sainz MJ, Ruiz González A, Téllez R, Cremades-Jimeno L, Cárdaba B, EU EOD Consortium, Van Broeckhoven C, Michlewski G, van der Zee J.

Alzheimers Dement. 2022 Dec 28.

PMID: 36576960

FI: 16,655

Functional neurological symptoms as initial presentation of Creutzfeldt-Jakob disease: case series.

Gómez-Mayordomo V, Kojovi? M, López-Valdés E, Alonso-Frech F, Horga A, Fernández-Rodríguez R, Pareés I.

J Neurol. 2022 Sep 30.

PMID: 36175672

FI: 6,682

The influence of the mass media on delusions: The Russia-Ukraine war as a delusional topic.

Cegla-Schvartzman F, Llaguno M, Baca-García E, Ovejero S.

Int J Soc Psychiatry. 2022 Jul 19:207640221109160.

PMID: 35850590

FI: 10,468

Chronic inhibition of the mitochondrial ATP synthase in skeletal muscle triggers sarcoplasmic reticulum distress and tubular aggregates.

Sánchez-González C, Herrero Martín JC, Salegi Ansa B, Núñez de Arenas C, Stančič B, Pereira MP, Contreras L, Cuezva JM, Formentini L.

Cell Death Dis. 2022 Jun 22.13(6):561.

PMID: 35732639

FI: 9,696

Implicit Cognition Tests for the Assessment of Suicide Risk: a Systematic Review.

Moreno M, Gutiérrez-Rojas L, Porras-Segovia A.

Curr Psychiatry Rep. 2022 02.24(2):141-159.

PMID: 35150387

FI: 8,081

• Área de Enfermedades Renales, Metabólicas y Cardiovasculares.

Daprodustat and On-Treatment Cardiovascular Events in Chronic Kidney Disease.

Rojas-Rivera J, Carriazo S, Ortiz A.

N Engl J Med. 2022 Dec 29.387(26):2481-2482.

PMID: 36577110

FI: 176,082

Reperfusion in ST-elevation myocardial infarction: delays have dangerous ends.

Coughlan JJ, Ibanez B.

Eur Heart J. 2022 Dec 14.

PMID: 36514965

FI: 35,855

Targeting inflammation to treat diabetic kidney disease: the road to 2030.

Rayego-Mateos S, Rodrigues-Diez RR, Fernandez-Fernandez B, Mora-Fernández C, Marchant V, Donate-Correa J, Navarro-González JF, Ortiz A, Ruiz-Ortega M.

Kidney Int. Epub 2022 Dec 05. 2023 Feb.103(2):282-296.

PMID: 36470394

FI: 18,998

Sex-Dependent Mediation of Leptin in the Association of Perilipin Polymorphisms with BMI and Plasma Lipid Levels in Children.

Vales-Villamarín C, Lumpuy-Castillo J, Gavela-Pérez T, de Dios O, Pérez-Nadador I, Soriano-Guillén L, Garcés C.

Nutrients. 2022 Jul 26.14(15).

PMID: 35893926

FI: 6,706

Bone marrow activation in response to metabolic syndrome and early atherosclerosis.

Devesa A, Lobo-González M, Martínez-Milla J, Oliva B, García-Lunar I, Mastrangelo A, España S, Sanz J, Mendiguren JM, Bueno H, Fuster JJ, Andrés V, Fernández-Ortiz A, Sancho D, Fernández-Friera L, Sanchez-Gonzalez J, Rossello X, Ibanez B, Fuster V.

Eur Heart J. 2022 05 14.43(19):1809-1828.

PMID: 35567559

FI: 35,855

• Área de Genética y Genómica.

A Dual Role for FADD in Human Precursor T-Cell Neoplasms.

Marín-Rubio JL, Vela-Martín L, Gudgeon J, Pérez-Gómez E, Sidgwick FR, Trost M, Cunningham DL, Santos J, Fernández-Piqueras J, Villa-Morales M.

Int J Mol Sci. 2022 Dec 02.23(23).

PMID: 36499482

FI: 6,208

Age-dependent association of clonal hematopoiesis with COVID-19 mortality in patients over 60 years.

Del Pozo-Valero M, Corton M, López-Rodríguez R, Mahillo-Fernández I, Ruiz-Hornillos J, Minguez P, Villaverde C, Pérez-Tomás ME, Barreda-Sánchez M, Mancebo E, STOP_Coronavirus Study Group, Paz-Artal E, Guillén-Navarro E, Almoguera B, Ayuso C.

Geroscience. 2022 Oct 03:1-11.

PMID: 36184726

FI: 7,581

A Large Case-Control Study Performed in Spanish Population Suggests That RECQL5 Is the Only RECQ Helicase Involved in Breast Cancer Susceptibility.

Marchena-Perea EM, Salazar-Hidalgo ME, Gómez-Sanz A, Arranz-Ledo M, Barroso A, Fernández V, Tejera-Pérez H, Pita G, Núñez-Torres R, Pombo L, Morales-Chamorro R, Cano-Cano JM, Soriano MDC, Garre P, Durán M, Currás-Freixes M, de la Hoya M, Osorio A.

Cancers (Basel). 2022 Sep 28.14(19).

PMID: 36230663

FI: 6,575

Aggregated Genomic Data as Cohort-Specific Allelic Frequencies can Boost Variants and Genes Prioritization in Non-Solved Cases of Inherited Retinal Dystrophies.

Iancu IF, Perea-Romero I, Núñez-Moreno G, de la Fuente L, Romero R, Ávila-Fernandez A, Trujillo-Tiebas MJ, Riveiro-Álvarez R, Almoguera B, Martín-Mérida I, Del Pozo-Valero M, Damián-Verde A, Cortón M, Ayuso C, Minguez P.

Int J Mol Sci. 2022 Jul 29.23(15).

PMID: 35955564

FI: 6,208

Quantifying telomeric lncRNAs using PNA-labelled RNA-Flow FISH (RNA-Flow).

González-Vasconcellos I, Cobos-Fernández MA, Atkinson MJ, Fernandez-Piqueras J, Santos J.

Commun Biol. 2022 05 25.5(1):513.

PMID: 35614335

FI: 6,548

• Área de Tecnología e Innovación Sanitaria.