A continuación se detallan las publicaciones más relevantes de 2020:

  • Área de Cáncer.

Phase I study of CC-90010, a reversible, oral BET inhibitor in patients with advanced solid tumors and relapsed/refractory non-Hodgkin's lymphoma.

Moreno V, Sepulveda JM, Vieito M, Hernández-Guerrero T, Doger B, Saavedra O, Ferrero O, Sarmiento R, Arias M, De Alvaro J, Di Martino J, Zuraek M, Sanchez-Pérez T, Aronchik I, Filvaroff EH, Lamba M, Hanna B, Nikolova Z, Braña I.

Annals of oncology. Epub 2020 Mar 30. 2020 Jun;31(6):780-788.

PMID: 32240793

FI: 18,274


Outcomes of COVID-19 in patients with CLL: a multicenter international experience.

Mato AR, Roeker LE, Lamanna N, Allan JN, Leslie L, Pagel JM, Patel K, Osterborg A, Wojenski D, Kamdar M, Huntington SF, Davids MS, Brown JR, Antic D, Jacobs R, Ahn IE, Pu J, Isaac KM, Barr PM, Ujjani CS, Geyer MB, Berman E, Zelenetz AD, Malakhov N, Furman RR, Koropsak M, Bailey N, Hanson L, Perini GF, Ma S, Ryan CE, Wiestner A, Portell CA, Shadman M, Chong EA, Brander DM, Sundaram S, Seddon AN, Seymour E, Patel M, Martinez-Calle N, Munir T, Walewska R, Broom A, Walter H, El-Sharkawi D, Parry H, Wilson MR, Patten PEM, Hernández-Rivas JÁ, Miras F, Fernández Escalada N, Ghione P, Nabhan C, Lebowitz S, Bhavsar E, López-Jiménez J, Naya D, Garcia-Marco JA, Skånland SS, Cordoba R, Eyre TA.

Blood. 2020 Sep 3;136(10):1134-1143.

PMID: 32688395

FI: 17,794


Clinical Impact and Regulation of the circCAMSAP1/ miR-328-5p/E2F1 Axis in Colorectal Cancer.

Cristóbal I, Luque M, Sanz-Alvarez M, Rojo F, García-Foncillas J.

Molecular therapy. Epub 2020 May 8. 2020 Jun 3;28(6):1387-1388.

PMID: 32413279

FI: 8,986


Generalized Pruriginous Eruption on a Patient With Leukemia.

Núñez-Hipólito L, Moya-Martínez C, Requena L.

JAMA dermatology. 2020 Dec 1;156(12):1369-1370.

PMID: 33112376

FI: 7,738


Peripheral T-cell lymphoma diagnosis: building a molecular tool.

Piris MA.

Haematologica. 2020 Jun;105(6):1472-1474.

PMID: 32482752

FI: 7,116


  • Área de Enfermedades Infecciosas, Inflamatorias y Crónicas.

Glucosamine and O-GlcNAcylation: a novel immunometabolic therapeutic target for OA and chronic, low-grade systemic inflammation?

Herrero-Beaumont G, Largo R.

Annals of the rheumatic diseases. Epub 2020 Jun 18. 2020 Oct;79(10):1261-1263.

PMID: 32554393

FI: 16,102


Clinical characteristics in 545 patients with severe asthma on biological treatment during the COVID-19 outbreak.

Rial MJ, Valverde M, Del Pozo V, González-Barcala FJ, Martínez-Rivera C, Muñoz X, Olaguibel JM, Plaza V, Curto E, Quirce S, Barranco P, Domínguez-Ortega J, Mullol J, Picado C, Valero A, Bobolea I, Arismendi E, Ribó P, Sastre J.

The journal of allergy and clinical immunology. In practice. 2020 Oct 9;S2213-2198(20)31100-4.

PMID: 33045398

FI: 7,574


Amino Acid Substitutions Associated with Treatment Failure for Hepatitis C Virus Infection.

Soria ME, García-Crespo C, Martínez-González B, Vázquez-Sirvent L, Lobo-Vega R, de Ávila AI, Gallego I, Chen Q, García-Cehic D, Llorens-Revull M, Briones C, Gómez J, Ferrer-Orta C, Verdaguer N, Gregori J, Rodríguez-Frías F, Buti M, Esteban JI, Domingo E, Quer J, Perales C.

Journal of clinical microbiology. Print 2020 Nov 18. 2020 Nov 18;58(12):e01985-20.

PMID: 32999010

FI: 5,897


Elite controllers: A heterogeneous group of HIV-infected patients.

Navarrete-Muñoz MA, Restrepo C, Benito JM, Rallón N.

Virulence. 2020 Dec;11(1):889-897.

PMID: 32698654

FI: 5,542


Patient Management Assisted by a Neural Network Reduces Mortality in an Intermediate Care Unit.

Heili-Frades S, Minguez P, Mahillo Fernández I, Jiménez Hiscock L, Santos A, Heili Frades D, Carballosa de Miguel MDP, Fernández Ormaechea I, Álvarez Suárez L, Naya Prieto A, González Mangado N, Peces-Barba Romero G.

Archivos de Bronconeumologia. Epub 2020 Jan 22. 2020 Sep;56(9):564-570.

PMID: 31982254

FI: 4,957


  • Área de Neurociencias.

Contribution of sleep deprivation to suicidal behaviour: A systematic review.

Porras-Segovia A, Pérez-Rodríguez MM, López-Esteban P, Courtet P, Barrigón M ML, López-Castromán J, Cervilla JA, Baca-García E.

Sleep medicine reviews. Epub 2018 Dec 11. 2019 Apr;44:37-47.

PMID: 30640161

FI: 9,607


Development of a computerized adaptive substance use disorder scale for screening and measurement: the CAT-SUD.

Gibbons RD, Alegria M, Markle S, Fuentes L, Zhang L, Carmona R, Collazos F, Wang Y, Baca-García E.

Addiction. Epub 2020 Jan 14. 2020 Jul;115(7):1382-1394.

PMID: 31943486

FI: 6,343


α-Secretase nonsense mutation (ADAM10 Tyr167*) in familial Alzheimer's disease.

Agüero P, Sainz MJ, García-Ayllón MS, Sáez-Valero J, Téllez R, Guerrero-López R, Pérez-Pérez J, Jiménez-Escrig A, Gómez-Tortosa E.

Alzheimer's research &therapy. 2020 Oct 31;12(1):139.

PMID: 33129344

FI: 6,116


βOHB Protective Pathways in Aralar-KO Neurons and Brain: An Alternative to Ketogenic Diet.

Pérez-Liébana I, Casarejos MJ, Alcaide A, Herrada-Soler E, Llorente-Folch I, Contreras L, Satrústegui J, Pardo B.

The Journal of neuroscience. Epub 2020 Oct 21. 2020 Nov 25;40(48):9293-9305.

PMID: 33087477

FI: 5,674


Structural and Functional Brain Abnormalities in Mouse Models of Lafora Disease.

Burgos DF, Cussó L, Sánchez-Elexpuru G, Calle D, Perpinyà MB, Desco M, Serratosa JM, Sánchez MP.

International journal of molecular sciences. 2020 Oct 20;21(20):7771.

PMID: 33092303

FI: 4,556


  • Área de Enfermedades Renales, Metabólicas y Cardiovasculares.

Givosiran for Acute Intermittent Porphyria.

Gomá-Garcés E, Pérez-Gómez MV, Ortíz A.

The New England journal of medicine. 2020 Nov 12;383(20):1989.

PMID: 33176091

FI: 74,699


The Obstacle Course of Reperfusion for STEMI in the COVID-19 Pandemics.

Roffi M, Guagliumi G, Ibanez B.

Circulation. Epub 2020 Apr 21. 2020 Jun 16;141(24):1951-1953.

PMID: 32315205

FI: 23,603


Effect of alirocumab on major adverse cardiovascular events according to renal function in patients with a recent acute coronary syndrome: prespecified analysis from the ODYSSEY OUTCOMES randomized clinical trial.

Tuñón J, Steg PG, Bhatt DL, Bittner VA, Díaz R, Goodman SG, Jukema JW, Kim YU, Li QH, Mueller C, Parkhomenko A, Pordy R, Sritara P, Szarek M, White HD, Zeiher AM, Schwartz GG, ODYSSEY OUTCOMES Investigators.

European heart journal. 2020 Nov 7;41(42):4114-4123.

PMID: 32820320

FI: 22,673


Targeting the progression of chronic kidney disease.

Ruiz-Ortega M, Rayego-Mateos S, Lamas S, Ortiz A, Rodrigues-Diez RR.

Nature reviews. Nephrology. Epub 2020 Feb 14. 2020 May;16(5):269-288.

PMID: 32060481

FI: 20,711


Complement C5 Protein as a Marker of Subclinical Atherosclerosis.

Martínez-López D, Roldan-Montero R, García-Marqués F, Nuñez E, Jorge I, Camafeita E, Minguez P, Rodriguez de Cordoba S, López-Melgar B, Lara-Pezzi E, Fernández-Ortiz A, Ibáñez B, Valdivielso JM, Fuster V, Michel JB, Blanco-Colio LM, Vázquez J, Martin-Ventura JL.

Journal of the American College of Cardiology. 2020 Apr 28;75(16):1926-1941.

PMID: 32327104

FI: 20,589


  • Área de Genética y Genómica.

CSVS, a crowdsourcing database of the Spanish population genetic variability.

Peña-Chilet M, Roldán G, Perez-Florido J, Ortuño FM, Carmona R, Aquino V, Lopez-Lopez D, Loucera C, Fernandez-Rueda JL, Gallego A, García-Garcia F, González-Neira A, Pita G, Núñez-Torres R, Santoyo-López J, Ayuso C, Minguez P, Avila-Fernandez A, Corton M, Moreno-Pelayo MÁ, Morin M, Gallego-Martinez A, Lopez-Escamez JA, Borrego S, Antiñolo G, Amigo J, Salgado-Garrido J, Pasalodos-Sanchez S, Morte B, Spanish Exome Crowdsourcing Consortium, Carracedo Á, Alonso Á, Dopazo J.

Nucleic acids research. Epub 2020 Sep 29. 2021 Jan 8;49(D1):D1130-D1137.

PMID: 32990755

FI: 11,502


More Insights on the Use of γ-Secretase Inhibitors in Cancer Treatment.

López-Nieva P, González-Sánchez L, Cobos-Fernández MÁ, Córdoba R, Santos J, Fernández-Piqueras J.

The oncologist. Epub 2020 Nov 15.

PMID: 33191568

FI: 5,025


Pathogenic variants in IMPG1 cause autosomal dominant and autosomal recessive retinitis pigmentosa.

Olivier G, Corton M, Intartaglia D, Verbakel SK, Sergouniotis PI, Le Meur G, Dhaenens CM, Naacke H, Avila-Fernández A, Hoyng CB, Klevering J, Bocquet B, Roubertie A, Sénéchal A, Banfi S, Muller A, Hamel CL, Black GC, Conte I, Roosing S, Zanlonghi X, Ayuso C, Meunier I, Manes G.

Journal of medical genetics. 2020 Aug 17;jmedgenet-2020-107150.

PMID: 32817297

FI: 4,943


Genotype-Phenotype Correlations in a Spanish Cohort of 506 Families With Biallelic ABCA4 Pathogenic Variants.

Del Pozo-Valero M, Riveiro-Alvarez R, Blanco-Kelly F, Aguirre-Lamban J, Martin-Merida I, Iancu IF, Swafiri S, Lorda-Sanchez I, Rodriguez-Pinilla E, Trujillo-Tiebas MJ, Jimenez-Rolando B, Carreño E, Mahillo-Fernandez I, Rivolta C, Corton M, Avila-Fernandez A, Garcia-Sandoval B, Ayuso C.

American journal of ophthalmology. Epub 2020 Jun 30. 2020 Nov;219:195-204.

PMID: 32619608

FI: 4,013


Genetic Material Manipulation and Modification by Optical Trapping and Nanosurgery-A Perspective.

Blázquez-Castro A, Fernández-Piqueras J, Santos J.

Frontiers in bioengineering and biotechnology. 2020 Sep 18;8:580937.

PMID: 33072730

FI: 3,644


  • Área de Tecnología e Innovación Sanitaria.

Necrotizing Scleritis.

Lorenzana Blanco N, Alejandre Alba N.

The New England journal of medicine. 2020 Nov 5;383(19):e110.

PMID: 33211932

FI: 74,699


Randomization versus Real-World Evidence.

Dal-Ré R, Mentz RJ, Rosendaal FR.

The New England journal of medicine. 2020 Jul 23;383(4):e21.

PMID: 32706548

FI: 74,699


Cell therapy with mesenchymal stem cells induces an innate immune memory response that attenuates experimental colitis in the long-term.

Lopez-Santalla M, Hervas-Salcedo R, Fernandez-Garcia M, Bueren JA, Garin MI.

Journal of Crohn's &colitis. 2020 Oct 5;14(10):1424-1435.

PMID: 32318720

FI: 8,658


Airway Management in Critically Ill Adults.

Gómez-Ríos MÁ, Casans-Francés R.

Chest. 2020 Dec;158(6):2711-2712.

PMID: 33280765

FI: 8,308


Liquid biopsy in peritoneal fluid and plasma as a prognostic factor in advanced colorectal and appendiceal tumors after complete cytoreduction and hyperthermic intraperitoneal chemotherapy.

López-Rojo I, Olmedillas-López S, Villarejo Campos P, Domínguez Prieto V, Barambio Buendía J, Cortés Guiral D, García-Arranz M, García-Olmo D.

Therapeutic advances in medical oncology. 2020 Dec 18;12:1758835920981351.

PMID: 33425029

FI: 6,852