Investigación en Nuevas Terapias

Resumen de actividad

- Desarrollo de implantes cocleares semi-ocultos y sin acúfenos y con hipoacusia asimétrica.

- Curso de entrenamiento quirúrgico en el área cervical.

- Desarrollo preclínico/clínico de tratamientos enzimáticos de carcinomatosis.

- Detección y valor predictivo de la presencia diferencial de exones mediante biopsia líquida.

- Desarrollo de un modelo de sepsis peritoneal y tratamiento mediante terapia celular.

- Desarrollo de ensayos clínicos en terapia celular.

Contribuciones a la sociedad

• Patentes desarrolladas: Bisturí químico. DPE en detección de Cáncer colorrectal. Nuevo tratamiento de las adherencias.
• Guías clínicas: Inclusión de la Terapia celular como tratamiento de 2ª línea en las fístulas perianales en pacientes con Crohn.
• Ensayos clínicos: Tratamiento de fístulas perianales mediante T.C.. Tratamiento de incontinencia anal mediante miocitos asociados a nanopartículas.
• Desarrollo de cursos formativos mediante el programa OPEREMOS.

Colaboraciones

• Empresa TAKEDA: estudio del efecto de la Terapia celular en el microambiente de la fístula perianal.
• Empresa EVOMED: desarrollo de un sistema de tratamiento enzimático co-adyuvante al HIPEC en Carcinomatosis peritoneal.
• ASANHEMO: desarrollo de un modelo "in vitro" de patología dirigida del Factor V de la coagulación mediante CRISPR.
• Empresa NIMGENETICS: estudio del valor predictivo/pronóstico de la PDE en cáncer colorrectal.
• Proyecto H2020 para puesta a punto y desarrollo de un ensayo clínico en incontinencia fecal mediante T.C.
• Proyecto RICORS del ISCIII. Red Nacional de terapias avanzadas (TERAV)
• Proyecto Comunidad de Madrid (Consorcio CellCAM), Red Autonómica de Medicina regenerativa.

Tesis doctorales

6.6.3-INV NUEVAS TERAP-TESIS

Relación de publicaciones ordenadas por fecha de publicación

Difficulties in Establishing ""Truth"" Conditions in the Assessment of Addictive Smartphone Use in Young Adults.

García-Manglano J, López-Madrigal C, Sádaba-Chalezquer C, Serrano C, Lopez-Fernandez O

International journal of environmental research and public health. 2021 Dec 30;19(1):358.

PMID: 35010618

FI: 3,39

Clinical evaluation of antiseptic mouth rinses to reduce salivary load of SARS-CoV-2.

Ferrer MD, Barrueco ÁS, Martinez-Beneyto Y, Mateos-Moreno MV, Ausina-Márquez V, García-Vázquez E, Puche-Torres M, Giner MJF, González AC, Coello JMS, Rueda IA, Aubá JMV, Español CC, Velasco AL, Abad DS, García-Esteban S, Artacho A, López-Labrador X, Mira A

Scientific reports. 2021 Dec 22;11(1):24392.

PMID: 34937855

FI: 4,38

Pulmonary Embolism in Patients with COVID-19: Comparison between Different Care Settings.

Buso G, Mazzolai L, Rueda-Camino JA, Fernández-Capitán C, Jiménez D, Bikdeli B, Lobo JL, Fernández-Reyes JL, Ciammaichella M, Monreal M, RIETE Investigators.

Seminars in thrombosis and hemostasis. 2021 Dec 13.

PMID: 34902865

FI: 4,18

Follow-up Study to Evaluate the Long-term Safety and Efficacy of Darvadstrocel (Mesenchymal Stem Cell Treatment) in Patients with Perianal Fistulizing Crohn's Disease: ADMIRE-CD Phase 3 Randomized Controlled Trial.

Garcia-Olmo D, Gilaberte I, Binek M, D Hoore AJ, Lindner D, Selvaggi F, Spinelli A, Panés J

Diseases of the colon and rectum. 2021 Dec 7.

PMID: 34890373

FI: 4,785

Next-generation three-dimensional modelling software for personalized surgery decision-making in perihilar cholangiocarcinoma: multicentre study.

Lopez-Lopez V, Gomez-Perez B, de Vicente E, Jiménez-Galanes S, Mora-Oliver I, Sabater L, Huber T, Lang H, Brusadin R, López Conesa A, Melendez R, Castro Santiago MJ, Ferreras D, Crespo MJ, Cayuela V, Robles-Campos R

The British journal of surgery. 2021 Dec 1;108(12):e394-e395.

PMID: 34542590

FI: 6,939

Surgical Wound Complications After Colorectal Surgery with Single-Use Negative-Pressure Wound Therapy Versus Surgical Dressing Over Closed Incisions: A Randomized Controlled Trial.

Arellano ML, Serrano CB, Guedea M, Garcia Pérez JC, Ortega GS, Guevara-Martinez J, Gomez Abril S, González Puga C, Arroyo A, Cantero Cid R

Advances in skin &wound care. 2021 Dec 1;34(12):657-661.

PMID: 34175866

FI: 2,347

Development of a health data derived frailty index as a predictor of adverse outcomes in older patients with pancreatic cancer.

Negrete-Najar JP, Sehovic M, Rodriquenz MG, Garcia-Martinez J, Extermann M

Journal of geriatric oncology. 2021 Nov 2;S1879-4068(21)00241-1.

PMID: 34740560

FI: 3,599

What happens to the bone structure after normocalcemic primary hyperparathyroidism surgery?

Osorio-Silla I, Gómez-Ramírez J, Valdazo-Gómez A, Salido Fernández S, Sánchez García C, Pardo García R

Surgery open science. 2021 Nov 1;S0039-6060(21)00869-2.

PMID: 34736792

FI: 3,982

Gallbladder disease and pancreatic cancer risk: a multicentric case-control European study.

Rosato V, Gómez-Rubio P, Molina-Montes E, Márquez M, Löhr M, O'Rorke M, Michalski CW, Molero X, Farré A, Perea J, Kleeff J, Crnogorac-Jurcevic T, Greenhalf W, Ilzarbe L, Tardón A, Gress T, Barberá VM, Domínguez-Muñoz E, Muñoz-Bellvís L, Balsells J, Costello E, Iglesias M, Kong B, Mora J, O'Driscoll D, Poves I, Scarpa A, Ye W, Hidalgo M, Sharp L, Carrato A, Real FX, La Vecchia C, Malats N, PanGenEU Study Investigators.

European journal of cancer prevention. 2021 Nov 1;30(6):423-430.

PMID: 34545020

FI: 2,497

The Role of CAR-T Cells in Peritoneal Carcinomatosis from Gastric Cancer: Rationale, Experimental Work, and Clinical Applications.

Qian S, Villarejo-Campos P, García-Olmo D

Journal of clinical medicine. 2021 Oct 28;10(21):5050.

PMID: 34768570

FI: 4,242

Early age of onset is an independent predictor for worse disease-free survival in sporadic rectal cancer patients. A comparative analysis of 980 consecutive patients.

Foppa C, Tamburello S, Maroli A, Carvello M, Poliani L, Laghi L, Malesci A, Montorsi M, Perea J, Spinelli A

European journal of surgical oncology. 2021 Oct 28;S0748-7983(21)00771-X.

PMID: 34740480

FI: 4,424

Bioethical Concerns During the COVID-19 Pandemic: What Did Healthcare Ethics Committees and Institutions State in Spain?

Ruiz-Hornillos J, Hernández Suárez P, Marín Martínez JM, de Miguel Beriain Í, Nieves Vázquez MA, Albert M, Herrera Abián M, Pacheco-Martínez PA, Trasmontes V, Guillén-Navarro E

Frontiers in public health. 2021 Oct 13;9:737755.

PMID: 34722445

FI: 3,709

Perinatal Adverse Effects in Newborns with Estimated Loss of Weight Percentile between the Third Trimester Ultrasound and Delivery. The GROWIN Study.

Galán Arévalo MS, Mahillo-Fernández I, Esteban LM, Andeyro-García M, Piñeiro Pérez R, Saénz de Pipaón M, Savirón-Cornudella R

Journal of clinical medicine. 2021 Oct 10;10(20):4643.

PMID: 34682766

FI: 4,242

The SARS-CoV-2 first wave impact in the acute inflammatory surgical pathologies.

Guadalajara H, Muñoz de Nova JL, Yiasemidou M, Recarte Rico M, Juez LD, García Septiem J, Galindo Jara P, García Virosta M, Lobo Martínez E, Martín-Pérez E, Fernandez Gonzalez S, Lopez-Fernandez O, García-Olmo D, PIACO Collaboration Group.

Scientific reports. 2021 Oct 4;11(1):19645.

PMID: 34608197

FI: 4,38

Spanish Research Network on Drugs in Hospital Emergency Departments - the REDUrHE registry: general analysis and comparisons between weekend and weekday poisonings.

Ibrahim-Achi D, Miró Ò, Galicia M, Supervía A, Puiguriguer Ferrando J, Ortega Pérez J, Leciñena MÁ, Venegas de L'Hotellerie MªJ, Rodríguez Miranda B, Martínez-Sánchez L, Bajo Bajo Á, Martín-Pérez B, Dueñas-Laita A, Ferrer Dufol A, Callado-Moro F, Nogué-Xarau S, Burillo-Putze G, Red de Estudio de Drogas en Urgencias Hospitalarias en España (REDUrHE).

Emergencias. 2021 Oct;33(5):335-344.

PMID: 34581526

FI: 3,881

Stemness of Human Pluripotent Cells: Hypoxia-Like Response Induced by Low Nitric Oxide.

Caballano-Infantes E, Díaz I, Hitos AB, Cahuana GM, Martínez-Ruiz A, Soria-Juan B, Rodríguez-Griñolo R, Hmadcha A, Martín F, Soria B, Tejedo JR, Bedoya FJ

Antioxidants. 2021 Sep 2;10(9):1408.

PMID: 34573040

FI: 6,313

Peritoneal calculomatosis.

Domínguez Prieto V, Qian Zhang S, Guijo Castellano I, Villarejo Campos P

Cirugia espanola. 2021 Sep 17;S0009-739X(21)00252-9.

PMID: 34544565

FI: 1,653

Organ preservation in rectal cancer, the desire of a new paradigm.

Domínguez Tristancho JL

Cirugia espanola. 2021 Sep 17;S0009-739X(21)00261-X.

PMID: 34544563

FI: 1,653

Timing of elective tracheotomy and duration of mechanical ventilation among patients admitted to intensive care with severe COVID-19: A multicenter prospective cohort study.

Prats-Uribe A, Tobed M, Villacampa JM, Agüero A, García-Bastida C, Tato JI, Rodrigáñez L, Holguera VD, Hernández-García E, Poletti D, Simonetti G, Villarraga V, Meler-Claramonte C, Sánchez Barrueco Á, Chiesa-Estomba C, Casasayas M, Parente-Arias P, Mata-Castro N, Rello J, Castro P, Prieto-Alhambra D, Vilaseca I, Avilés-Jurado FX, TraqueoCOVID SEORL Group.

Head &neck. Epub 2021 Sep 15. 2021 Dec;43(12):3743-3756.

PMID: 34524714

FI: 3,147

Prognosis of unexpected positive intraoperative cultures in arthroplasty revision: A large multicenter cohort.

Mancheño-Losa M, Lora-Tamayo J, Fernández-Sampedro M, Rodríguez-Pardo D, Muñoz-Mahamud E, Soldevila L, Palou M, Barbero JM, Del Toro MD, Iribarren JA, Sobrino B, Rico-Nieto A, Guío-Carrión L, Gómez L, Escudero-Sánchez R, García-País MJ, Jover-Sáenz A, Praena J, Baraia-Etxaburu JM, Auñón Á, Múñez-Rubio E, Murillo O, List of study collaborators. (Jaime Esteban, Joaquín García-Cañete)

The Journal of infection. Epub 2021 Sep 9. 2021 Nov;83(5):542-549.

PMID: 34509512

FI: 6,072

A case-control analysis of stroke in Covid-19 patients: Results of Unusual Manifestations of Covid-19-Study 11.

Jorge García-Lamberechts E, Miró Ò, Fragiel M, Llorens P, Jiménez S, Piñera P, Burillo G, Martín A, Martín-Sánchez FJ, Jacob J, Alquézar-Arbé A, Ejarque Martínez L, Rodríguez Miranda B, Ruiz Grinspan M, Domínguez MJ, Teigell Muñoz FJ, Gayoso Martín S, García García A, Iglesias Vela M, Carbajosa V, Salido M, Marchena González MJ, Agüera Urbano C, Porta-Etessam J, Calvo E, Del Castillo JG, Spanish Investigators on Emergency Situations TeAm (SIESTA) network.

Academic emergency medicine. Epub 2021 Sep 29. 2021 Nov;28(11):1236-1250.

PMID: 34490961

FI: 3,451

Exploring adherence to treatment in nasal polyposis.

Valverde-Monge M, Barroso B, Ortega-Martin L, Betancor D, Santillan J, Villacampa JM, Sastre J

Journal of investigational allergology &clinical immunology. 2021 Sep 3;0.

PMID: 34489223

FI: 7,033

Skin lesions, weakness, and axillary adenopathies in a 44-year-old woman.

Rueda-Camino JA, Robles-Barrena I, Vegas-Sánchez MC

European journal of internal medicine. Epub 2021 Sep 4. 2021 Nov;93:95-96.

PMID: 34489163

FI: 4,624

Efficacy and safety of intramuscular administration of allogeneic adipose tissue derived and expanded mesenchymal stromal cells in diabetic patients with critical limb ischemia with no possibility of revascularization: study protocol for a randomized controlled double-blind phase II clinical trial (The NOMA Trial).

Soria-Juan B, Garcia-Arranz M, Llanos Jiménez L, Aparicio C, Gonzalez A, Mahillo Fernandez I, Riera Del Moral L, Grochowicz L, Andreu EJ, Marin P, Castellanos G, Moraleda JM, García-Hernández AM, Lozano FS, Sanchez-Guijo F, Villarón EM, Parra ML, Yañez RM, de la Cuesta Diaz A, Tejedo JR, Bedoya FJ, Martin F, Miralles M, Del Rio Sola L, Fernández-Santos ME, Ligero JM, Morant F, Hernández-Blasco L, Andreu E, Hmadcha A, Garcia-Olmo D, Soria B

Trials. 2021 Sep 6;22(1):595.

PMID: 34488845

FI: 2,279

Patient education program at the forefront of cancer-associated thrombosis care.

Sebuhyan M, Crichi B, Deville L, Le Maignan C, Bonnet C, Marjanovic Z, Rueda J, Bensaoula O, Ndour A, Frere C, Madeleine I, Farge D

Journal de medecine vasculaire. Epub 2021 Aug 24. Oct-Dec 2021;46(5-6):215-223.

PMID: 34862015

FI: 0

Germline CDH1 G212E Missense Variant: Combining Clinical, In Vitro and In Vivo Strategies to Unravel Disease Burden.

Figueiredo J, Mercadillo F, Melo S, Barroso A, Gonçalves M, Díaz-Tasende J, Carneiro P, Robles L, Colina F, Ibarrola C, Perea J, Morais-de-Sá E, Seruca R, Urioste M

Cancers. 2021 Aug 28;13(17):4359.

PMID: 34503169

FI: 6,639

Effect of the Implementation of a Surgical Care Bundle in the Incidence of Surgical Site Infection in Spine Surgery: A Quasi-Experimental Study.

Vicente-Sánchez G, Alonso-García M, Hijas-Gómez AI, González-Díaz R, Martínez-Martín J, Fahandezh-Saddi H, Durán-Poveda M, De Miguel AG, Rodríguez-Caravaca G

Spine. 2021 Aug 30.

PMID: 34468435

FI: 3,468

Is it necessary to perform a follow-up study after adenotonsillectomy in all children with moderate-severe obstructive sleep apnoea?

Del-Río Camacho G, Torre Francisco R, Rodríguez Catalán J, Sanabria Brossart J, López Gómez R, Troncoso Acevedo F

Acta otorrinolaringologica espanola. 2021 Aug 27;S0001-6519(21)00095-9.

PMID: 34462116

FI: 0

Protocol for assessing mortality reduction with the early use of noninvasive ventilation in prehospital emergency services: A multicentre, observational cohort study in Madrid, Spain.

Horrillo García C, Cintora Sanz AM, Gutierrez Misis A, Gómez-Morán Quintana M, Torres Poza A, Carrillo Fernández O, Rendo Murillo JA, Perez Alonso AM, Pastor Cabanillas L, Carrillo Fernández A, Chaya Romero C, García Oliva RC, Mazuecos Muñoz D, Mir Montero M, Leco Gil N, Parejo García L, Rubio Riballo AB, Canales Corcho I, Barreiro Martínez C, Ibañez Concejo AT, Del Caño Garrido A, Fernández Egido C, García Herrero GM, Borge Toledano G, Lafuente Durá JM, Lacalle Calleja EM, Escorial Sanz O, Parada Otte V, López Martín S, Morales Pérez J, Miguens Blanco I, Lafuente Saenz R, Uzuriaga Martín M, Rubio Chacón C, Cantó Blázquez V, VentilaMadrid group.

Australian critical care. 2021 Aug 18;S1036-7314(21)00088-6.

PMID: 34419341

FI: 2,737

Early discharge and postpartum home visit during the COVID-19 pandemic at the HULP (Madrid).

Feijóo-Iglesias MB, Chicharro Chorro L, Ballester Escolar I, Suárez Pascual A, De la Peña Rodríguez MA, Alba Diego RM

Revista espanola de salud publica. 2021 Aug 19;95:e202108105.

PMID: 34408124

FI: 0,756

Massive Perirenal Involvement in Erdheim-Chester Disease.

Polo-Sabau J, López-Botet-Zulueta B

Radiology. Epub 2021 Aug 17. 2021 Nov;301(2):278.

PMID: 34402662

FI: 11,105

Usefulness of endonasal flaps and grafts in skull base surgery Consensus document.

Moreno-Luna R, Mariño Sánchez F, Kaen A, Gras Cabrerizo JR, Mata Castro N, González García J, Villacampa Aubá JM, Cárdenas Ruiz-Valdepeñas E, Monjas Cánovas I, Del Cuvillo Bernal A, García Piñero A, Maza Solano JM, Fernández de Liesa R, Sánchez-Gómez S, Alobid I

Acta otorrinolaringologica espanola. 2021 Jul 28;S0001-6519(21)00041-8.

PMID: 34330369

FI: 0

Diagnostic yield of clinical exome sequencing in congenital hypogonadotropic hypogonadism considering the degree of olfactory impairment.

Ortiz-Cabrera NV, Gavela-Pérez T, Mejorado-Molano FJ, Santillán-Coello JM, Villacampa-Aubá JM, Trujillo-Tiebas MJ, Soriano-Guillén L

Anales de pediatria. 2021 Jul 5;S2341-2879(21)00111-3.

PMID: 34238712

FI: 1,5

Diagnostic concordance between Primary Care and Mental Health.

Molina JD, Benavente López S, Andrés Prado MJ, Pérez Ros Y, Rubio Valladolid G, Rodríguez-Jiménez R

Actas espanolas de psiquiatria. 2021 Jul;49(4):129-134.

PMID: 34195968

FI: 1,196

Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study.

Chaparro M, Garre A, Núñez Ortiz A, Diz-Lois Palomares MT, Rodríguez C, Riestra S, Vela M, Benítez JM, Fernández Salgado E, Sánchez Rodríguez E, Hernández V, Ferreiro-Iglesias R, Ponferrada Díaz Á, Barrio J, Huguet JM, Sicilia B, Martín-Arranz MD, Calvet X, Ginard D, Alonso-Abreu I, Fernández-Salazar L, Varela Trastoy P, Rivero M, Vera-Mendoza I, Vega P, Navarro P, Sierra M, Cabriada JL, Aguas M, Vicente R, Navarro-Llavat M, Echarri A, Gomollón F, Guerra Del Río E, Piñero C, Casanova MJ, Spicakova K, Ortiz de Zarate J, Torrella Cortés E, Gutiérrez A, Alonso-Galán H, Hernández-Martínez Á, Marrero JM, Lorente Poyatos R, Calafat M, Martí Romero L, Robledo P, Bosch O, Jiménez N, Esteve Comas M, Duque JM, Fuentes Coronel AM, Josefa Sampedro M, Sesé Abizanda E, Herreros Martínez B, Pozzati L, Fernández Rosáenz H, Crespo Suarez B, López Serrano P, Lucendo AJ, Muñoz Vicente M, Bermejo F, Ramírez Palanca JJ, Menacho M, Carmona A, Camargo R, Torra Alsina S, Maroto N, Nerín de la Puerta J, Castro E, Marín-Jiménez I, Botella B, Sapiña A, Cruz N, Forcelledo JLF, Bouhmidi A, Castaño-Milla C, Opio V, Nicolás I, Kutz M, Abraldes Bechiarelli A, Gordillo J, Ber Y, Torres Domínguez Y, Novella Durán MT, Rodríguez Mondéjar S, Martínez-Cerezo FJ, Kolle L, Sabat M, Ledezma C, Iyo E, Roncero Ó, Irisarri R, Lluis L, Blázquez Gómez I, Zapata EM, José Alcalá M, Martínez Pascual C, Montealegre M, Mata L, Monrobel A, Hernández Camba A, Hernández L, Tejada M, Mir A, Galve ML, Soler M, Hervías D, Gómez-Valero JA, Barreiro-de Acosta M, Rodríguez-Artalejo F, García-Esquinas E, Gisbert JP, On Behalf Of The EpidemIBD Study Group Of Geteccu

Journal of clinical medicine. 2021 Jun 29;10(13):2885.

PMID: 34209680

FI: 4,242

Anxiety and Worries among Pregnant Women during the COVID-19 Pandemic: A Multilevel Analysis.

Esteban-Gonzalo S, Caballero-Galilea M, González-Pascual JL, Álvaro-Navidad M, Esteban-Gonzalo L

International journal of environmental research and public health. 2021 Jun 26;18(13):6875.

PMID: 34206849

FI: 3,39

Towards an Open Medical School without Checkerboards during the COVID-19 Pandemic: How to Flexibly Self-Manage General Surgery Practices in Hospitals?

Guadalajara H, Palazón Á, Lopez-Fernandez O, Esteban-Flores P, Garcia JM, Gutiérrez-Misis A, Baca-García E, Garcia-Olmo D

Healthcare. 2021 Jun 17;9(6):743.

PMID: 34204496

FI: 2,645

Efficacy and safety of preoperative preparation with Lugol's iodine solution in euthyroid patients with Graves' disease (LIGRADIS Trial): Study protocol for a multicenter randomized trial.

Muñoz de Nova JL, Franch-Arcas G, Mejía-Abril GP, Flores-Ruiz ME, Muñoz-Pérez N, Pintos-Sánchez E, Guadarrama González FJ, Valdés de Anca Á, Mercader-Cidoncha E, de la Quintana-Basarrate A, Osorio-Silla I, Ros-López S, Gallego-Otaegui L, Santos-Molina E, Martínez-Nieto C, Gamborino-Caramés E, Artés-Caselles M, Lorente-Poch L, García-Carrillo M, Moreno-Llorente P, Marín-Velarde C, Ortega-Serrano J, Martos-Martínez JM, Vidal-Pérez O, Luengo-Pierrard P, Villar-Del-Moral JM

Contemporary clinical trials communications. 2021 Jun 15;22:100806.

PMID: 34195471

FI: 0

Core outcome set for surgical trials in gastric cancer (GASTROS study): international patient and healthcare professional consensus.

Alkhaffaf B, Metryka A, Blazeby JM, Glenny AM, Adeyeye A, Costa PM, Diez Del Val I, Gisbertz SS, Guner A, Law S, Lee HJ, Li Z, Nakada K, Reim D, Vorwald P, Baiocchi GL, Allum W, Chaudry MA, Griffiths EA, Williamson PR, Bruce IA

The British journal of surgery. 2021 Jun 24;znab192.

PMID: 34165555

FI: 6,939

Management of thyroid and parathyroid surgery in major ambulatory surgery.

de la Fuente Bartolomé M, Sánchez de Molina Rampérez ML, García Vasquez C, Vieiro Medina MV, Jiménez de Los Galanes Marchan SF

Cirugia espanola. 2021 Jun 19;S0009-739X(21)00211-6.

PMID: 34158163

FI: 1,653

Methods for conducting international Delphi surveys to optimise global participation in core outcome set development: a case study in gastric cancer informed by a comprehensive literature review.

Alkhaffaf B, Blazeby JM, Metryka A, Glenny AM, Adeyeye A, Costa PM, Del Val ID, Gisbertz SS, Guner A, Law S, Lee HJ, Li Z, Nakada K, Nuñez RMR, Reim D, Reynolds JV, Vorwald P, Zanotti D, Allum W, Chaudry MA, Griffiths E, Williamson PR, Bruce IA, GASTROS International Working Group.

Trials. 2021 Jun 21;22(1):410.

PMID: 34154641

FI: 2,279

Plasma D-dimer value corrected by inflammatory markers in patients with SARS-CoV-2 infection: Its prognostic value in the diagnosis of venous thromboembolism.

Rueda-Camino JA, Sendín-Martín V, Joya-Seijo MD, Angelina-García M, Zamarro-García C, Gimena-Rodríguez FJ, Barba-Martín R

Medicina clinica. 2021 Jun 3;S0025-7753(21)00253-0.

PMID: 34144801

FI: 1,725

Implementation barriers for Enhanced Recovery After Surgery (ERAS) in rectal cancer surgery: a comparative analysis of compliance with colon cancer surgeries.

Tejedor P, González Ayora S, Ortega López M, León Arellano M, Guadalajara H, García-Olmo D, Pastor C

Updates in surgery. 2021 Jun 18.

PMID: 34143398

FI: 2,797

Ectopic pregnancies and endometrial microbiota.

Aguilera LL, García IC, Quevedo IC

Current opinion in obstetrics &gynecology. 2021 Jun 1;33(3):202-206.

PMID: 33896916

FI: 1,927

Gut instinct: a call to study the biology of early-onset colorectal cancer disparities.

Holowatyj AN, Perea J, Lieu CH

Nature reviews. Cancer. 2021 Jun;21(6):339-340.

PMID: 33833408

FI: 60,716

Costal deformity with hepatic compression as unusual abdominal pain.

de la Fuente Bartolomé M, García Vasquez C, Rihuete Caro C, Jiménez de Los Galanes S

Cirugia espanola. Epub 2021 May 19. Jun-Jul 2021;99(6):465.

PMID: 34130817

FI: 1,653

Graft infusion of adipose-derived mesenchymal stromal cells to prevent rejection in experimental intestinal transplantation: A feasibility study (vol 35, e14226, 2021).

Andres, AM; Stringa, P; Talayero, P; Santamaria, M; Garcia-Arranz, M; Gomez-Heras, SG; Largo-Aramburu, C; Aras-Lopez, RM; Vallejo-Cremades, MT; Pastrian, LG; Vega, L; Encinas, JL; Lopez-Santamaria, M; Hernandez-Oliveros, F

Clinical Transplantation. 2021 May;35(6):e14343.

PMID: 34003529

FI: 2,863

Effect of a Surgical Care Bundle on the Incidence of Surgical Site Infection in Colorectal Surgery: A Quasi-Experimental Intervention.

Zarain-Obrador L, Alonso-García M, Gil-Yonte P, Hijas-Gómez AI, Rodríguez-Villar D, Martínez-Amores B, Gil-de-Miguel Á, Ruiz-Tovar J, Rodríguez-Caravaca G, Durán-Poveda M

Revista de Investigacion Clinica-Clinical and Translational Investigation 2021 May 4;73(4):251-258.

PMID: 33944860

FI: 1,451

Total intrapartum fetal reperfusion time (fetal resilience) and neonatal acidemia.

Chóliz Ezquerro M, Savirón Cornudella R, Esteban LM, Zamora Del Pozo C, Espiau Romera A, Castán Larraz B, Castán Mateo S

The journal of maternal-fetal &neonatal medicine. 2021 May 2;1-10.

PMID: 33938352

FI: 2,398

Right-sided Bochdalek hernia associated with an intrathoracic kidney in an adult.

Salcedo G, Velez F, Posada M, Barragan C, Vorwald P

Surgery open science. Epub 2021 Apr 19. 2021 Oct;170(4):e13-e14.

PMID: 34602185

FI: 3,982

COVID-19 and the education of health professionals in mental health: Challenges in practical teaching.

Ovejero S, Barrigon ML, Guadalajara H, Pérez-Santos E, Baca-Garcia E

Revista de psiquiatria y salud mental. Epub 2021 May 24. Apr-Jun 2021;14(2):119-121.

PMID: 34099437

FI: 3,318

Comparative Analysis Between Mesenchymal Stem Cells From Subcutaneous Adipose Tissue and Omentum in Three Types of Patients: Cancer, Morbid Obese and Healthy Control.

Posada-González M, Villagrasa A, García-Arranz M, Vorwald P, Olivera R, Olmedillas-López S, Vega-Clemente L, Salcedo G, García-Olmo D

Surgical innovation. 2021 Apr 30;15533506211013142.

PMID: 33929270

FI: 2,058

Is Re-introducing Major Open and Minimally Invasive Surgery during COVID-19 Safe for Patients and Healthcare Workers? An International, Multi-centre Cohort Study in the Field of Oesophago-gastric Surgery.

Alasmar M, Kausar A, Borgstein AB, Moons J, Doran S, de Pascale S, Restrepo R, Verrengia A, Alloggio M, Delgado AM, Kumar S, Del Val ID, Giocapuzzi S, Baiocchi GL, de Vega Irañeta M, Salcedo G, Vorwald P, Fumagalli Romario U, Nafteux P, Gisbertz S, Chaudry MA, Alkhaffaf B

Annals of surgical oncology. 2021 Apr 17;1-11.

PMID: 33866473

FI: 5,344

Vulvar intra-epithelial neoplasia: Screening in population at risk.

Gil, CA; Baro, RS; Herraez, IB; Borrego, IMF; Dominguez, LP; Guisasola, CR

Clinica e Investigacion En Ginecologia Y Obstetricia. 2021 Apr-Jun;48(2):117-121.

PMID:

FI: 0

Usefulness of histological superstudy of sentinel lymph nodes detected with radioisotopes in colon cancer.

Serrano Del Moral Á, Pérez Viejo E, Castaño Pascual Á, Llorente Herrero E, Rodríguez Caravaca G, Duran Poveda M, Pereira Pérez F

Revista espanola de medicina nuclear e imagen molecular. Epub 2021 Mar 30. Nov-Dec 2021;40(6):358-366.

PMID: 34752369

FI: 1,359

The Current Status of Mesenchymal Stromal Cells: Controversies, Unresolved Issues and Some Promising Solutions to Improve Their Therapeutic Efficacy.

García-Bernal D, García-Arranz M, Yáñez RM, Hervás-Salcedo R, Cortés A, Fernández-García M, Hernando-Rodríguez M, Quintana-Bustamante Ó, Bueren JA, García-Olmo D, Moraleda JM, Segovia JC, Zapata AG

Frontiers in cell and developmental biology. 2021 Mar 16;9:650664.

PMID: 33796536

FI: 6,684

Substance use, mental health and dual disorders on pregnancy: results of prevalence and treatment rates in a developed country.

Carmona Camacho R, López Carpintero N, Barrigón ML, Ruiz Nogales C, Menéndez I, Sánchez Alonso M, Caro Cañizares I, Hernández Aguado JJ, Le Cook B, Alegría M, Saviron Cornudella R, Plaza J, Baca-García E

Adicciones. 2021 Mar 12;0(0):1568.

PMID: 33768264

FI: 2,979

Multicentre cohort study of acute cholecystitis management during the COVID-19 pandemic.

Martínez Caballero J, González González L, Rodríguez Cuéllar E, Ferrero Herrero E, Pérez Algar C, Vaello Jodra V, Pérez Díaz MD, Dziakova J, San Román Romanillos R, Di Martino M, de la Hoz Rodríguez Á, Galán Martín M, Sánchez López D, García Virosta M, de la Fuente Bartolomé M, Pardo de Lama MM, Gutiérrez Samaniego M, Díaz Pérez D, Alias Jiménez D, de Nicolás Navas L, Pérez Alegre JJ, García-Quijada García J, Guevara-Martínez J, Villadoniga A, Martínez Fernández R

European journal of trauma and emergency surgery. Epub 2021 Mar 19. 2021 Jun;47(3):683-692.

PMID: 33742223

FI: 3,693

Evaluation of the effectiveness of a new cryopreservation system based on a two-compartment vial for the cryopreservation of cell therapy products.

Rosell-Valle C, Antúnez C, Campos F, Gallot N, García-Arranz M, García-Olmo D, Gutierrez R, Hernán R, Herrera C, Jiménez R, Leyva-Fernández L, Maldonado-Sanchez R, Muñoz-Fernández R, Nogueras S, Ortiz L, Piudo I, Ranchal I, Rodríguez-Acosta A, Segovia C, Fernández-Muñoz B

Cytotherapy. Epub 2021 Mar 11. 2021 Aug;23(8):740-753.

PMID: 33714705

FI: 5,414

Development and validation of a predictive model of in-hospital mortality in COVID-19 patients.

Velasco-Rodríguez D, Alonso-Dominguez JM, Vidal Laso R, Lainez-González D, García-Raso A, Martín-Herrero S, Herrero A, Martínez Alfonzo I, Serrano-López J, Jiménez-Barral E, Nistal S, Pérez Márquez M, Askari E, Castillo Álvarez J, Núñez A, Jiménez Rodríguez Á, Heili-Frades S, Pérez-Calvo C, Górgolas M, Barba R, Llamas-Sillero P

PloS one. 2021 Mar 4;16(3):e0247676.

PMID: 33661939

FI: 3,24

Management of early gestations with low beta-hCG levels after the use of assisted reproduction techniques: assessment of the M4 predictive model performance.

Valdera Simbrón CJ, Hernández Rodríguez C, Llanos Jiménez L, Pérez García L, Plaza Arranz J, Albi González M

Ultrasound in obstetrics & gynecology. 2021 Mar 3.

PMID: 33656199

FI: 7,299

3D reconstruction of presacral tumours prior to Kraske procedure-a video vignette.

Vélez PInto JF, Leon Arellano M, Vizarreta A, Barambio J, Ortega M, Guadalajara H

Colorectal disease. Epub 2021 Mar 4. 2021 May;23(5):1283.

PMID: 33554440

FI: 3,788

Sudden hearing loss as the main symptom of bilateral ischemic stroke secondary to fibroelastoma of the aortic valve.

Peiró Villalba C, Albiñana Pérez A, Casas Movilla C

Medicina clinica. Epub 2021 Jul 3. 2022 Feb 25;158(4):190-191.

PMID: 34229880

FI: 1,725

The Listening Network and Cochlear Implant Benefits in Hearing-Impaired Adults.

James CJ, Graham PL, Betances Reinoso FA, Breuning SN, Durko M, Huarte Irujo A, Royo López J, Müller L, Perenyi A, Jaramillo Saffon R, Salinas Garcia S, Schüssler M, Schwarz Langer MJ, Skarzynski PH, Mecklenburg DJ

Frontiers in aging neuroscience. 2021 Feb 25;13:589296.

PMID: 33716706

FI: 5,75

Usefulness of histological superstudy of sentinel node detected with radioisotope in colon cancer.

Serrano Del Moral Á, Pérez Viejo E, Castaño Pascual Á, Llorente Herrero E, Rodríguez Caravaca G, Durán Poveda M, Pereira Pérez F

Revista espanola de medicina nuclear e imagen molecular. 2021 Feb 26;S2253-654X(21)00017-2.

PMID: 33642258

FI: 1,359

A live porcine model for surgical training in tracheostomy, neck dissection, and total laryngectomy.

Alcalá Rueda I, Villacampa Aubá JM, Encinas Vicente A, Gabernet MB, Guerrero CC, Reparaz CCC, de Freitas ET, González AC, Español CC

European archives of oto-rhino-laryngology. Epub 2021 Feb 18. 2021 Aug;278(8):3081-3090.

PMID: 33598732

FI: 2,503

Nursing students' experience and training in healthcare aid during the COVID-19 pandemic in Spain.

Hernández-Martínez A, Rodríguez-Almagro J, Martínez-Arce A, Romero-Blanco C, García-Iglesias JJ, Gómez-Salgado J

Journal of clinical nursing. 2021 Feb 15;10.1111/jocn.15706.

PMID: 33590573

FI: 3,036

Internal audit of oncological results in gastric cancer surgery.

Rihuete-Caro C, Pereira-Pérez F, Manzanedo-Romero I, Carrión-Álvarez L

Cirugia espanola. 2021 Feb 10;S0009-739X(21)00026-9.

PMID: 33581842

FI: 1,653

Enhanced anti-inflammatory effects of mesenchymal stromal cells mediated by the transient ectopic expression of CXCR4 and IL10.

Hervás-Salcedo R, Fernández-García M, Hernando-Rodríguez M, Quintana-Bustamante O, Segovia JC, Alvarez-Silva M, García-Arranz M, Minguez P, Del Pozo V, de Alba MR, García-Olmo D, Ayuso C, Lamana ML, Bueren JA, Yañez RM

Stem cell research &therapy. 2021 Feb 12;12(1):124.

PMID: 33579367

FI: 6,832

Where Have All The Nasal Polyposis Gone?

Ortega-Martin L, Betancor D, Barroso B, Valverde-Monge M, Santillan J, Villacampa JM, Sastre J

Journal of investigational allergology &clinical immunology. 2021 Feb 11;0.

PMID: 33574016

FI: 7,033

Effectiveness of Text Message Reminders on Adherence to Inhaled Therapy in Patients With Asthma: Prospective Multicenter Randomized Clinical Trial.

Almonacid C, Melero C, López Viña A, Cisneros C, Pérez de Llano L, Plaza V, García-Rivero JL, Romero Falcón A, Ramos J, Bazús González T, Andrés Prado M, Muriel A

JMIR formative research. 2021 Feb 9;5(2):e12218.

PMID: 33560235

FI: 0

Squamous cell carcinoma arising from an epidermal inclusion cyst in breast: An extremely rare diagnosis.

Hernández-Villafranca S, Osorio I, Salido S, Qian S, Bernar J, Cazorla Jiménez A, Astilleros Blanco de Córdova L, Pardo R

The breast journal. Epub 2021 Feb 8. 2021 Feb;27(2):176-177.

PMID: 33555075

FI: 2,431

Impact of individualized management of breakthrough cancer pain on quality of life in advanced cancer patients: CAVIDIOPAL study.

Tuca Rodríguez A, Núñez Viejo M, Maradey P, Canal-Sotelo J, Guardia Mancilla P, Gutiérrez Rivero S, Raja Casillas I, Herrera Abián M, López Bermudo C

Supportive care in cancer. Epub 2021 Feb 3. 2021 Aug;29(8):4799-4807.

PMID: 33533986

FI: 3,603

A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer.

López de Maturana E, Rodríguez JA, Alonso L, Lao O, Molina-Montes E, Martín-Antoniano IA, Gómez-Rubio P, Lawlor R, Carrato A, Hidalgo M, Iglesias M, Molero X, Löhr M, Michalski C, Perea J, O'Rorke M, Barberà VM, Tardón A, Farré A, Muñoz-Bellvís L, Crnogorac-Jurcevic T, Domínguez-Muñoz E, Gress T, Greenhalf W, Sharp L, Arnes L, Cecchini L, Balsells J, Costello E, Ilzarbe L, Kleeff J, Kong B, Márquez M, Mora J, O'Driscoll D, Scarpa A, Ye W, Yu J, PanGenEU Investigators., García-Closas M, Kogevinas M, Rothman N, Silverman DT, SBC/EPICURO Investigators., Albanes D, Arslan AA, Beane-Freeman L, Bracci PM, Brennan P, Bueno-de-Mesquita B, Buring J, Canzian F, Du M, Gallinger S, Gaziano JM, Goodman PJ, Gunter M, LeMarchand L, Li D, Neale RE, Peters U, Petersen GM, Risch HA, Sánchez MJ, Shu XO, Thornquist MD, Visvanathan K, Zheng W, Chanock SJ, Easton D, Wolpin BM, Stolzenberg-Solomon RZ, Klein AP, Amundadottir LT, Marti-Renom MA, Real FX, Malats N

Genome medicine. 2021 Feb 1;13(1):15.

PMID: 33517887

FI: 11,117

Graft infusion of adipose-derived mesenchymal stromal cells to prevent rejection in experimental intestinal transplantation: A feasibility study.

Andres AM, Stringa P, Talayero P, Santamaria M, García-Arranz M, García Gómez-Heras S, Largo-Aramburu C, Aras-Lopez RM, Vallejo-Cremades MT, Guerra Pastrián L, Vega L, Encinas JL, Lopez-Santamaria M, Hernández-Oliveros F

Clinical transplantation. Epub 2021 Feb 5. 2021 Apr;35(4):e14226.

PMID: 33465824

FI: 2,863

Tratamiento del embarazo ectópico en cicatriz de cesárea. Revisión de la literatura a propósito de 3 casos.

Pradillo A, Tamara; Sevilla R, José; Valdés R, María Luisa; Pérez C, Esther; Fraga C, Silvia; González R, Montserrat; Laguna H, María; Bordés I, María; Sobrino L, Lara; Rodríguez C, Juan Miguel

Revista chilena de obstetricia y ginecología. 2021 Feb;86(1):104-119.

PMID:

FI: 0

Necrotizing fasciitis as a complication of late anastomotic leak after anterior resection for rectal cancer.

Domínguez-Prieto V, León-Arellano M, Alvarellos-Pérez A, Ortega-López M, Pastor C

Cirugia y cirujanos. 2021;89(S2):80-83.

PMID: 34932541

FI: 0,361

Current and Emerging Applications of Droplet Digital PCR in Oncology: An Updated Review.

Olmedillas-López S, Olivera-Salazar R, García-Arranz M, García-Olmo D

Molecular diagnosis &therapy. Epub 2021 Nov 13. 2022 Jan;26(1):61-87.

PMID: 34773243

FI: 4,074

Incidence of surgical infection and risk factors in colorectal surgery - A prospective cohort study.

Páramo-Zunzunegui J, Alonso-García M, Rodríguez-Villar D, Drewniak-Jakubowska J, Calvo-Espino P, Cuberes-Montserrat R, Rodríguez-Caravaca G, Durán-Poveda M

Cirugia y cirujanos. 2021;89(2):156-162.

PMID: 33784283

FI: 0,361

Author response to: Comment on: Patterns of acute surgical inflammatory processes presentation of in the COVID-19 outbreak (PIACO Study): surgery may be the best treatment option.

Guadalajara H, Muñoz de Nova JL, Fernandez Gonzalez S, Yiasemidou M, Recarte Rico M, Juez LD, García Septiem J, Galindo Jara P, García Virosta M, Lobo Martínez E, Martín-Pérez E, García-Olmo D, PIACO Collaboration Group.

The British journal of surgery. 2021 Jan 27;108(1):e42-e43.

PMID: 33640951

FI: 6,939

Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic.

COVIDSurg Collaborative.(Albi Martin B, García Villayzán JE)(Moliner-Sánchez C, Pingarron-Martin L, Rey-Biel J, Ruiz Martin I )

The British journal of surgery. 2021 Jan 27;108(1):88-96.

PMID: 33640908

FI: 6,939

Development and internal validation of a prediction model for hospital-acquired acute kidney injury.

Martin-Cleary C, Molinero-Casares LM, Ortiz A, Arce-Obieta JM

Clinical kidney journal. Epub 2021 Jan;14(1):309-316.

PMID: 33564433

FI: 4,452

A clinico-pathological and molecular analysis reveals differences between solitary (early and late-onset) and synchronous rectal cancer.

Perea J, García JL, Corchete L, Tapial S, Olmedillas-López S, Vivas A, García-Olmo D, Urioste M, Goel A, González-Sarmiento R

Scientific reports. 2021 Jan 26;11(1):2202.

PMID: 33500439

FI: 4,38

Intraperitoneal collagenase as a novel therapeutic approach in an experimental model of colorectal peritoneal carcinomatosis.

García-Olmo D, Villarejo Campos P, Barambio J, Gomez-Heras SG, Vega-Clemente L, Olmedillas-Lopez S, Guadalajara H, Garcia-Arranz M

Scientific reports. 2021 Jan 12;11(1):503.

PMID: 33436728

FI: 4,38

Emerging Health and Education Issues Related to Internet Technologies and Addictive Problems.

Lopez-Fernandez O

International journal of environmental research and public health. 2021 Jan 4;18(1):321.

PMID: 33406806

FI: 3,39

Analysis of clinical characteristics and outcomes in patients with COVID-19 based on a series of 1000 patients treated in Spanish emergency departments.

Gil-Rodrigo A, Miró Ò, Piñera P, Burillo-Putze G, Jiménez S, Martín A, Martín-Sánchez FJ, Jacob J, Guardiola JM, García-Lamberechts EJ, Espinosa B, Martín Mojarro E, González Tejera M, Serrano L, Agüera C, Soy E, Llauger L, Juan MÁ, Palau A, Del Arco C, Rodríguez Miranda B, Maza Vera MT, Martín Quirós A, Tejada de Los Santos L, Ruiz de Lobera N, Iglesias Vela M, Torres Garate R, Alquézar-Arbé A, González Del Castillo J, Llorens P, en representación de la red de investigación SIESTA.

Emergencias. 2020 Ago;32(4):233-241.

PMID: 32692000

FI: 3,881

Application of Vitamin E Acetate on Staple Lines and Anastomoses of Roux-en-Y Gastric Bypass: Impact on Postoperative Pain and Acute Phase Reactants.

Ruiz-Tovar J, Garcia A, Ferrigni C, Duran M

Obesity surgery. 2020 Aug;30(8):2988-2993.

PMID: 32342266

FI: 4,129

Acute Care Surgery during the COVID-19 pandemic in Spain: Changes in volume, causes and complications. A multicentre retrospective cohort study.

Cano-Valderrama O, Morales X, Ferrigni CJ, Martín-Antona E, Turrado V, García A, Cuñarro-López Y, Zarain-Obrador L, Duran-Poveda M, Balibrea JM, Torres AJ

International journal of surgery. Epub 2020 Jul 15. 2020 Aug;80:157-161.

PMID: 32679205

FI: 6,071

Prevalence of Endoscopic Findings Before Bariatric Surgery and Their Influence on the Selection of the Surgical Technique.

García-Gómez-Heras S, Garcia A, Zubiaga L, Artuñedo P, Ferrigni C, Duran M, Ruiz-Tovar J

Obesity surgery. Epub 2020 Jun 25. 2020 Nov;30(11):4375-4380.

PMID: 32588172

FI: 4,129

Reduction in emergency surgery activity during COVID-19 pandemic in three Spanish hospitals.

Cano-Valderrama O, Morales X, Ferrigni CJ, Martín-Antona E, Turrado V, García A, Cuñarro-López Y, Zarain-Obrador L, Duran-Poveda M, Balibrea JM, Torres AJ

The British journal of surgery. Epub 2020 May 14. 2020 Jul;107(8):e239.

PMID: 32406929

FI: 6,939

Surgical site infection prevention measures in General Surgery: Position statement by the Surgical Infections Division of the Spanish Association of Surgery.

Badia JM, Rubio Pérez I, Manuel A, Membrilla E, Ruiz-Tovar J, Muñoz-Casares C, Arias-Díaz J, Jimeno J, Guirao X, Balibrea JM

Cirugia espanola. 2020 Apr;98(4):187-203.

PMID: 31983392

FI: 1,653

Gastroesophageal reflux disease in a patient with a body mass index of 30 kg/m² and previous endoscopic sleeve gastroplasty: Indication for a one-anastomosis gastric bypass. Response to a letter to the editor.

Ruiz-Tovar J

Cirugia espanola. 2020 Feb;98(2):113-114.

PMID: 31791656

FI: 1,653

Analgesic effect of postoperative laparoscopic-guided transversus abdominis plane (TAP) block, associated with preoperative port-site infiltration, within an enhanced recovery after surgery protocol in one-anastomosis gastric bypass: a randomized clinical trial.

Ruiz-Tovar J, Gonzalez G, Sarmiento A, Carbajo MA, Ortiz-de-Solorzano J, Castro MJ, Jimenez JM, Zubiaga L

Surgical endoscopy. Epub 2020 Jan 13. 2020 Dec;34(12):5455-5460.

PMID: 31932932

FI: 4,584

Adjuvant chemotherapy in locally advanced rectal cancer: deciding on the optimal strategy.

de Torres-Olombrada MV, Juez-Martel I, Rodríguez-Caravaca G, Duran-Poveda M

Revista de Investigacion Clinica-Clinical and Translational Investigation 2020;72(2):88-94.

PMID: 32284624

FI: 1,451