Responsables

  • Gabriel Herrero-Beaumont (Profesor Titular de la UAM)
  • Raquel Largo Carazo

IP

  • Aránzazu Mediero Muñoz
  • Esperanza Naredo Sánchez

Investigación

  • Básica
  • Clínica

Producción Científica

Resumen 2017


Nº total de publicaciones

Nº de publicaciones con FI

FI Acumulado

FI medio anual

Nº REVISTAS Q1

(%) Q1

58

53

240,45

4,54

29

54,72%


Publicaciones 2017


EULAR recommendations for the use of imaging in the clinical management of peripheral joint osteoarthritis.

Sakellariou G, Conaghan PG, Zhang W, Bijlsma JWJ, Boyesen P, D'Agostino MA, Doherty M, Fodor D, Kloppenburg M, Miese F, Naredo E, Porcheret M, Iagnocco A.

Annals of the rheumatic diseases. 2017 Sep Volume: 76 Issue: 9 Pages: 1484-1494.

PMID: 28389554

FI: 12,811

Antisynthetase syndrome or what else? Different perspectives indicate the need for new classification criteria.

Cavagna L, Castañeda S, Sciré C, Gonzalez-Gay MA, AENEAS Collaborative Group Members..

Annals of the rheumatic diseases. 2017 Sep 25.

PMID: 28970214

FI: 12,811

The 2017 EULAR standardised procedures for ultrasound imaging in rheumatology.

Möller I, Janta I, Backhaus M, Ohrndorf S, Bong DA, Martinoli C, Filippucci E, Sconfienza LM, Terslev L, Damjanov N, Hammer HB, Sudol-Szopinska I, Grassi W, Balint P, Bruyn GAW, D'Agostino MA, Hollander D, Siddle HJ, Supp G, Schmidt WA, Iagnocco A, Koski J, Kane D, Fodor D, Bruns A, Mandl P, Kaeley GS, Micu M, Ho C, Vlad V, Chávez-López M, Filippou G, Cerón CE, Nestorova R, Quintero M, Wakefield R, Carmona L, Naredo E.

Annals of the rheumatic diseases. 2017 Dec;76(12):1974-1979.

PMID: 28814430

FI: 12,811

Use of Intra-Articular Hyaluronic Acid in the Management of Knee Osteoarthritis in Clinical Practice.

Cooper C, Rannou F, Richette P, Bruyère O, Al-Daghri N, Altman RD, Luisa Brandi M, Collaud Basset S, Herrero-Beaumont G, Migliore A, Pavelka K, Uebelhart D, Reginster JY.

Arthritis care &research. 2017 Sep;69(9):1287-1296.

PMID: 28118523

FI: 3,319

Age-related vascularization and ossification of joints in children: an international pilot study to test multi-observer ultrasound reliability.

Windschall D, Collado P, Vojinovic J, Magni-Manzoni S, Balint P, Bruyn GAW, Hernandez-Diaz C, Nieto JC, Ravagnani V, Tzaribachev N, Iagnocco A, D'Agostino MA, Naredo E, OMERACT paediatric ultrasound subtask force..

Arthritis care & research. 2017 Aug 4.

PMID: 28777893

FI: 3,319

Increased synovial lipodystrophy induced by high fat diet aggravates synovitis in experimental osteoarthritis.

Larrañaga-Vera A, Lamuedra A, Pérez-Baos S, Prieto-Potin I, Peña L, Herrero-Beaumont G, Largo R.

Arthritis research & therapy. 2017 Dec 1 Volume: 19 Issue: 1 Pages: 264.

PMID: 29191221

FI: 4,121

Evaluation of bacterial adherence of clinical isolates of <i>Staphylococcus sp.</i> using a competitive model: An <i>in vitro</i> approach to the "race for the surface" theory.

Martinez-Perez M, Perez-Jorge C, Lozano D, Portal-Nuñez S, Perez-Tanoira R, Conde A, Arenas MA, Hernandez-Lopez JM, de Damborenea JJ, Gomez-Barrena E, Esbrit P, Esteban J.

Bone & joint research 2017 May Volume: 6 Issue: 5 Pages: 315-322.

PMID: 28522445

FI: 2,425

Tofacitinib restores the inhibition of reverse cholesterol transport induced by inflammation: understanding the lipid paradox associated with rheumatoid arthritis.

Pérez-Baos S, Barrasa JI, Gratal P, Larrañaga-Vera A, Prieto-Potin I, Herrero-Beaumont G, Largo R.

British journal of pharmacology. 2017 Sep;174(18):3018-3031.

PMID: 28646516

FI: 5,259

Impact of Chiropractic Manipulation on Bone and Skeletal Muscle of Ovariectomized Rats.

López-Herradón A, Fujikawa R, Gómez-Marín M, Stedile-Lovatel JP, Mulero F, Ardura JA, Ruiz P, Muñoz I, Esbrit P, Mahíllo-Fernández I, Ortega-de Mues A.

Calcified tissue international. 2017 Nov;101(5):519-529.

PMID: 28755011

FI: 3,016

Ultrasound of the osteoarthritic joint.

Iagnocco A, Naredo E.

Clinical and experimental rheumatology. 2017 May-Jun;35(3):527-534.

PMID: 28229810

FI: 2,634

Exploring the remission concept in rheumatoid arthritis with patients and rheumatologists: time for a new approach?

Acebes C, Andreu JL, Balsa A, Battle E, de Toro-Santos J, García Llorente F, Hernández MV, Fernández-Gutiérrez B, Hidalgo-Calleja C, Mayordomo L, Naredo E, Narváez FJ, Ortiz AM, Pablos JL, Pérez-Sandoval T, Rodríguez-Lozano C, Sánchez-Pernaute O, Usón J, Negrón JB, Loza E, Carmona L, Gómez Castro S, Montoro Alvarez M.

Clinical and experimental rheumatology. 2017 Sep-Oct;35(5):816-822.

PMID: 28516881

FI: 2,634

One year in review 2017: ultrasound in crystal arthritis.

Naredo E, Iagnocco A.

Clinical and experimental rheumatology. 2017 May-Jun Volume: 35 Issue: 3 Pages: 362-367.

PMID: 28631607

FI: 2,634

An exploratory study to determine whether infliximab modifies levels of rheumatoid factor and antibodies to cyclic citrullinated peptides in rheumatoid arthritis patients.

Martínez-Estupiñán L, Hernández-Flórez D, Janta I, Ovalles-Bonilla JG, Nieto JC, González-Fernández CM, Del Río T, Monteagudo I, López-Longo FJ, Naredo E, Valor L.

Clinical and experimental rheumatology. 2017 Aug 28.

PMID: 28850020

FI: 2,634

Uric acid is independent cardiovascular risk factor, as manifested by increased carotid intima-media thickness in rheumatoid arthritis patients.

Hannawi S, AlSalmi I, Moller I, Naredo E.

Clinical rheumatology. 2017 Aug;36(8):1897-1902.

PMID: 28664292

FI: 2,365

From a formal training program in musculoskeletal ultrasound (MSUS) to a high reproducibility for Doppler ultrasound in rheumatoid arthritis.

Villota O, Diaz M, Ceron C, Moller I, Naredo E, Saaibi DL.

Current rheumatology reviews. 2017 Jul 28.

PMID: 28758585

FI: 0

Erratum to: Can We Identify Patients with High Risk of Osteoarthritis Progression Who Will Respond to Treatment? A Focus on Epidemiology and Phenotype of Osteoarthritis.

Bruyère O, Cooper C, Arden N, Branco J, Brandi ML, Herrero-Beaumont G, Berenbaum F, Dennison E, Devogelaer JP, Hochberg M, Kanis J, Laslop A, McAlindon T, Reiter S, Richette P, Rizzoli R, Reginster JY.

Drugs &aging. 2017 May;34(5):411.

PMID: 28349414

FI: 2,769

High Glucose Alters the Secretome of Mechanically Stimulated Osteocyte-like Cells Affecting Osteoclast Precursor Recruitment and Differentiation.

Maycas M, Portolés MT, Matesanz MC, Buendía I, Linares J, Feito MJ, Arcos D, Vallet-Regí M, Plotkin L, Esbrit P, Gortázar AR.

Journal of cellular physiology. 2017 Dec;232(12):3611-3621.

PMID: 28138960

FI: 4,080

Lipoprotein(a) concentrations in rheumatoid arthritis on biologic therapy: Results from the CARdiovascular in rheuMAtology study project.

García-Gómez C, Martín-Martínez MA, Castañeda S, Sanchez-Alonso F, Uriarte-Ecenarro M, González-Juanatey C, Romera-Baures M, Santos-Rey J, Pinto-Tasende JA, Quesada-Masachs E, Tornero-Molina J, Martínez-González O, Cobo-Ibáñez T, Chamizo-Carmona E, Manrique-Arija S, Fábregas-Canales D, Díaz-González F, Llorca J, González-Gay MA, CARMA Project Collaborative Group. (Naredo E).

Journal of clinical lipidology. 2017 May - Jun Volume: 11 Issue: 3 Pages: 749-756.e3.

PMID: 28476652

FI: 5,812

Corrigendum to "New and Emerging Therapies for Osteoporosis".

Lewiecki EM, Diaz Curiel M, Borges JL, Kung A, Brandi ML, Dimai HP.

Journal of osteoporosis. 2017 Volume: 2017 Issue: Pages: 4175180.

PMID: 28744390

FI: 0

Clinical settings in knee osteoarthritis: Pathophysiology guides treatment.

Herrero-Beaumont G, Roman-Blas JA, Bruyère O, Cooper C, Kanis J, Maggi S, Rizzoli R, Reginster JY.

Maturitas. 2017 Feb Volume: 96 Issue: Pages: 54-57.

PMID: 28041596

FI: 3,255

Osteoarthritis: Chondroitin sulfate - CONCEPT clear, uncertainties unchanged.

Herrero-Beaumont G, Largo R.

Nature reviews. Rheumatology. 2017 Oct;13(10):576-577.

PMID: 28814816

FI: 12,188

The OMERACT Ultrasound Group: A Report from the OMERACT 2016 Meeting and Perspectives.

Terslev L, Iagnocco A, Bruyn GA, Naredo E, Vojinovic J, Collado P, Damjanov N, Filer A, Filippou G, Finzel S, Gandjbakhch F, Ikeda K, Keen HI, Kortekaas MC, Magni-Manzoni S, Ohrndorf S, Pineda C, Ravagnani V, Richards B, Sahbudin I, Schmidt WA, Siddle HJ, Stoenoiu MS, Szkudlarek M, Tzaribachev N, D'Agostino MA, OMERACT Ultrasound Group..

New standards in arthritis care : proceedings of an ILAR symposium, Rio De Janeiro, Brazil, September 18, 1989 2017 Nov;44(11):1740-1743.

PMID: 28148700

FI: 3,236

Definition and Reliability Assessment of Elementary Ultrasonographic Findings in Calcium Pyrophosphate Deposition Disease: A Study by the OMERACT Calcium Pyrophosphate Deposition Disease Ultrasound Subtask Force.

Filippou G, Scirè CA, Damjanov N, Adinolfi A, Carrara G, Picerno V, Toscano C, Bruyn GA, D'Agostino MA, Delle Sedie A, Filippucci E, Gutierrez M, Micu M, Möller I, Naredo E, Pineda C, Porta F, Schmidt WA, Terslev L, Vlad V, Zufferey P, Iagnocco A.

New standards in arthritis care : proceedings of an ILAR symposium, Rio De Janeiro, Brazil, September 18, 1989 2017 Nov;44(11):1744-1749.

PMID: 28250136

FI: 3,236

The Use of the OMERACT Ultrasound Tenosynovitis Scoring System in Multicenter Clinical Trials.

Ammitzbøll-Danielsen M, Østergaard M, Naredo E, Iagnocco A, Möller I, D'Agostino MA, Gandjbakhch F, Terslev L.

New standards in arthritis care : proceedings of an ILAR symposium, Rio De Janeiro, Brazil, September 18, 1989 2017 Dec 15.

PMID: 29247153

FI: 3,150

2017 update on the relationship between diabetes and colorectal cancer: epidemiology, potential molecular mechanisms and therapeutic implications.

González N, Prieto I, Del Puerto-Nevado L, Portal-Nuñez S, Ardura JA, Corton M, Fernández-Fernández B, Aguilera O, Gomez-Guerrero C, Mas S, Moreno JA, Ruiz-Ortega M, Sanz AB, Sanchez-Niño MD, Rojo F, Vivanco F, Esbrit P, Ayuso C, Alvarez-Llamas G, Egido J, García-Foncillas J, Ortiz A, Consortium DC.

Oncotarget 2017 Mar 14;8(11):18456-18485.

PMID: 28060743

FI: 5,168

Quality of life for up to 18 months after low-energy hip, vertebral, and distal forearm fractures-results from the ICUROS.

Svedbom A, Borgstöm F, Hernlund E, Ström O, Alekna V, Bianchi ML, Clark P, Curiel MD, Dimai HP, Jürisson M, Kallikorm R, Lember M, Lesnyak O, McCloskey E, Sanders KM, Silverman S, Solodovnikov A, Tamulaitiene M, Thomas T, Toroptsova N, Uusküla A, Tosteson ANA, Jönsson B, Kanis JA.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2017 Dec 11.

PMID: 29230511

FI: 3,591

Colon cancer modulation by a diabetic environment: A single institutional experience.

Prieto I, Del Puerto-Nevado L, Gonzalez N, Portal-Nuñez S, Zazo S, Corton M, Minguez P, Gomez-Guerrero C, Arce JM, Sanz AB, Mas S, Aguilera O, Alvarez-Llamas G, Esbrit P, Ortiz A, Ayuso C, Egido J, Rojo F, Garcia-Foncillas J, DiabetesCancerConnect Consortium..

PLoS hub for clinical trials 2017 Volume: 12 Issue: 3 Pages: e0172300.

PMID: 28253286

FI: 2,806

The antiviral drug tenofovir, an inhibitor of Pannexin-1-mediated ATP release, prevents liver and skin fibrosis by downregulating adenosine levels in the liver and skin.

Feig JL, Mediero A, Corciulo C, Liu H, Zhang J, Perez-Aso M, Picard L, Wilder T, Cronstein B.

PLoS hub for clinical trials 2017 Volume: 12 Issue: 11 Pages: e0188135.

PMID: 29145453

FI: 2,806

Quality of life after hip, vertebral, and distal forearm fragility fractures measured using the EQ-5D-3L, EQ-VAS, and time-trade-off: results from the ICUROS.

Svedbom A, Borgström F, Hernlund E, Ström O, Alekna V, Bianchi ML, Clark P, Curiel MD, Dimai HP, Jürisson M, Uusküla A, Lember M, Kallikorm R, Lesnyak O, McCloskey E, Ershova O, Sanders KM, Silverman S, Tamulaitiene M, Thomas T, Tosteson ANA, Jönsson B, Kanis JA.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 2017 Dec 12.

PMID: 29235059

FI: 2,344

Epigenetic therapies, still in the midway between facts and fiction.

Sánchez-Pernaute O.

Reumatología clinica. 2017 Nov - Dec;13(6):311-312.

PMID: 28571731

FI: 0

An international SUrvey on non-iNvaSive tecHniques to assess the mIcrocirculation in patients with RayNaud's phEnomenon (SUNSHINE survey).

Ingegnoli F, Ughi N, Dinsdale G, Orenti A, Boracchi P, Allanore Y, Foeldvari I, Sulli A, Cutolo M, Smith V, Herrick AL, EULAR Study Group on Microcirculation in RheumaticDiseases..

Rheumatology international. 2017 Nov;37(11):1879-1890.

PMID: 28894946

FI: 1,824

The challenge of the definition of early symptomatic knee osteoarthritis: a proposal of criteria and red flags from an international initiative promoted by the Italian Society for Rheumatology.

Migliore A, Scirè CA, Carmona L, Beaumont GH, Bizzi E, Branco J, Carrara G, Chevalier X, Collaku L, Aslanidis S, Denisov L, Di Matteo L, Bianchi G, Diracoglu D, Frediani B, Maheu E, Martusevich N, Bagnato GF, Scarpellini M, Minisola G, Akkoc N, Ramonda R, Barskova T, Babic-Naglic D, Muelas JVM, Ionescu R, Rashkov R, Damjanov N, Cerinic MM.

Rheumatology international. 2017 Aug;37(8):1227-1236.

PMID: 28451793

FI: 1,824

Erratum to: The challenge of the definition of early symptomatic knee osteoarthritis: a proposal of criteria and red flags from an international initiative promoted by the Italian Society for Rheumatology.

Migliore A, Scirè CA, Carmona L, Herrero-Beaumont G, Bizzi E, Branco J, Carrara G, Chevalier X, Collaku L, Aslanidis S, Denisov L, Di Matteo L, Bianchi G, Diracoglu D, Frediani B, Maheu E, Martusevich N, Bagnato GF, Scarpellini M, Minisola G, Akkoc N, Ramonda R, Barskova T, Babic-Naglic D, Muelas JVM, Ionescu R, Rashkov R, Damjanov N, Cerinic MM.

Rheumatology international. 2017 Aug;37(8):1237-1238.

PMID: 28523419

FI: 1,824

Epigenetics and complex diseases, a new era in the assessment of exposure and risk?

Sánchez-Pernaute O, Gabucio A.

Rheumatology. 2017 Nov 2.

PMID: 29112759

FI: 4,818

Scoring ultrasound synovitis in rheumatoid arthritis: a EULAR-OMERACT ultrasound taskforce<b>-</b>Part 1: definition and development of a standardised, consensus-based scoring system.

D'Agostino MA, Terslev L, Aegerter P, Backhaus M, Balint P, Bruyn GA, Filippucci E, Grassi W, Iagnocco A, Jousse-Joulin S, Kane D, Naredo E, Schmidt W, Szkudlarek M, Conaghan PG, Wakefield RJ.

RMD open. 2017 Volume: 3 Issue: 1 Pages: e000428.

PMID: 28948983

FI: 0

Scoring ultrasound synovitis in rheumatoid arthritis: a EULAR-OMERACT ultrasound taskforce-Part 2: reliability and application to multiple joints of a standardised consensus-based scoring system.

Terslev L, Naredo E, Aegerter P, Wakefield RJ, Backhaus M, Balint P, Bruyn GAW, Iagnocco A, Jousse-Joulin S, Schmidt WA, Szkudlarek M, Conaghan PG, Filippucci E, D'Agostino MA.

RMD open. 2017 Volume: 3 Issue: 1 Pages: e000427.

PMID: 28948984

FI: 0

SNPs in bone-related miRNAs are associated with the osteoporotic phenotype.

De-Ugarte L, Caro-Molina E, Rodríguez-Sanz M, García-Pérez MA, Olmos JM, Sosa-Henríquez M, Pérez-Cano R, Gómez-Alonso C, Del Rio L, Mateo-Agudo J, Blázquez-Cabrera JA, González-Macías J, Pino-Montes JD, Muñoz-Torres M, Diaz-Curiel M, Malouf J, Cano A, Pérez-Castrillon JL, Nogues X, Garcia-Giralt N, Diez-Perez A.

Scientific reports. 2017 Mar 31 Volume: 7 Issue: 1 Pages: 516.

PMID: 28364128

FI: 4,259

Analysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy.

Carmona FD, Coit P, Saruhan-Direskeneli G, Hernández-Rodríguez J, Cid MC, Solans R, Castañeda S, Vaglio A, Direskeneli H, Merkel PA, Boiardi L, Salvarani C, González-Gay MA, Martín J, Sawalha AH, Spanish GCA Study Group., Italian GCA Study Group., Turkish Takayasu Study Group., Vasculitis Clinical Research Consortium..

Scientific reports. 2017 Mar 9 Volume: 7 Issue: Pages: 43953.

PMID: 28277489

FI: 4,259

Corrigendum: Analysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy.

Carmona FD, Coit P, Saruhan-Direskeneli G, Hernández-Rodríguez J, Cid MC, Solans R, Castañeda S, Vaglio A, Direskeneli H, Merkel PA, Boiardi L, Salvarani C, González-Gay MA, Martín J, Sawalha AH, Spanish GCA Study Group., Italian GCA Study Group., Turkish Takayasu Study Group., Vasculitis Clinical Research Consortium..

Scientific reports. 2017 Apr 5 Volume: 7 Issue: Pages: 46012.

PMID: 28378796

FI: 4,259

Compensatory anabolic signaling in the sarcopenia of experimental chronic arthritis.

Little RD, Prieto-Potin I, Pérez-Baos S, Villalvilla A, Gratal P, Cicuttini F, Largo R, Herrero-Beaumont G.

Scientific reports. 2017 Jul 24 Volume: 7 Issue: 1 Pages: 6311.

PMID: 28740214

FI: 4,259

Hepatobiliary involvement in systemic sclerosis and the cutaneous subsets: Characteristics and survival of patients from the Spanish RESCLE Registry.

Marí-Alfonso B, Simeón-Aznar CP, Guillén-Del Castillo A, Rubio-Rivas M, Trapiella-Martínez L, Todolí-Parra JA, Rodríguez Carballeira M, Marín-Ballvé A, Iniesta-Arandia N, Colunga-Argüelles D, Castillo-Palma MJ, Sáez-Comet L, Egurbide-Arberas MV, Ortego-Centeno N, Freire M, Vargas Hitos JA, Chamorro AJ, Madroñero-Vuelta AB, Perales-Fraile I, Pla-Salas X, Fernández-De-La-Puebla RA, Fonollosa-Pla V, Tolosa-Vilella C, RESCLE Investigators., Systemic Autoimmune Diseases Study Group (GEAS)..

Seminars in arthritis and rheumatism. 2017 Oct 6.

PMID: 29246416

FI: 4,498

Anti-senescence and Anti-inflammatory Effects of the C-terminal Moiety of PTHrP Peptides in OA Osteoblasts

Platas J, Guillén MI, Gomar F, Castejón MA, Esbrit P, Alcaraz MJ.

The journals of gerontology. Series A, Biological sciences and medical sciences. 2017 May 1 Volume: 72 Issue: 5 Pages: 624-631.

PMID: 27271252

FI: 5,957

The Usefulness of Bone Biomarkers for Monitoring Treatment Disease: A Comparative Study in Osteolytic and Osteosclerotic Bone Metastasis Models.

Martín-Fernández M, Valencia K, Zandueta C, Ormazábal C, Martínez-Canarias S, Lecanda F, de la Piedra C.

Translational oncology 2017 Apr Volume: 10 Issue: 2 Pages: 255-261.

PMID: 28214773

FI: 3,025

Effects of Cyclosporine, Tacrolimus, and Rapamycin on Osteoblasts.

Martín-Fernández M, Rubert M, Montero M, de la Piedra C.

Transplantation proceedings. 2017 Nov Volume: 49 Issue: 9 Pages: 2219-2224.

PMID: 29149986

FI: 0,908

Unexpected Bone Formation Produced by RANKL Blockade.

Portal-Núñez S, Mediero A, Esbrit P, Sánchez-Pernaute O, Largo R, Herrero-Beaumont G.

Trends in endocrinology and metabolism : TEM. 2017 Oct;28(10):695-704.

PMID: 28733136

FI: 10,893

Sonographic and Anatomic Description of the Subtalar Joint.

Mandl P, Bong D, Balint PV, Hammer HB, Miguel M, Naredo E, Terslev L, Möller I, Anatomy for the Image Study Group..

Ultrasound in medicine & biology. 2017 Nov 6.

PMID: 29122317

FI: 2,494

Tenosynovitis Evaluation Using Image Fusion and B-Flow - A Pilot Study on New Imaging Techniques in Rheumatoid Arthritis Patients.

Ammitzbøll-Danielsen M, Glinatsi D, Torp-Pedersen S, Møller JM, Naredo E, Ostergaard M, Terslev L.

Ultrasound international open. 2017 Jun Volume: 38 Issue: 3 Pages: 285-293.

PMID: 28511227

FI: 4,434

Intramuscular versus ultrasound-guided intratenosynovial glucocorticoid injection for tenosynovitis in patients with rheumatoid arthritis: a randomised, double-blind, controlled study.

Ammitzbøll-Danielsen M, Østergaard M, Fana V, Glinatsi D, Døhn UM, Ørnbjerg LM, Naredo E, Terslev L.

Annals of the rheumatic diseases. 2017 Apr;76(4):666-672..

PMID: 27604532

FI: 12,811

Preliminary Definitions for the Sonographic Features of Synovitis in Children.

Roth J, Ravagnani V, Backhaus M, Balint P, Bruns A, Bruyn GA, Collado P, De la Cruz L, Guillaume-Czitrom S, Herlin T, Hernandez C, Iagnocco A, Jousse-Joulin S, Lanni S, Lilleby V, Malattia C, Magni-Manzoni S, Modesto C, Rodriguez A, Nieto JC, Ohrndorf S, Rossi-Semerano L, Selvaag AM, Swen N, Ting TV, Tzaribachev N, Vega-Fernandez P, Vojinovic J, Windschall D, D'Agostino MA, Naredo E, OMERACT Ultrasound Group..

Arthritis care &research. 2017 Aug;69(8):1217-1223..

PMID: 27748074

FI: 3,319

Hemophagocytic lymphohistiocytosis in a patient with Sjögren's syndrome: case report and review.

García-Montoya L, Sáenz-Tenorio CN, Janta I, Menárguez J, López-Longo FJ, Monteagudo I, Naredo E.

Rheumatology international. 2017 Apr;37(4):663-669.

PMID: 27853859

FI: 1,824

Guidelines for the conduct of pharmacological clinical trials in hand osteoarthritis: Consensus of a Working Group of the European Society on Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO)

Reginster JL, Arden NK, Haugen IK, Rannou F, Cavalier E, Bruyère O, Branco J, Chapurlat R, Collaud Basset S, Al-Daghri NM, Dennison EM, Herrero-Beaumont G, Laslop A, Leeb BF, Maggi S, Mkinsi O, Povzun AS, Prieto-Alhambra D, Thomas T, Uebelhart D, Veronese N, Cooper C.

Seminars in arthritis and rheumatism 2017 Dec 7.

PMID: 29287769

FI: 4,498

Reply

Roman-Blas JA, Sánchez-Pernaute O, Largo R, Herrero-Beaumont G.

Arthritis & rheumatology 2017 Jul 13.

PMID: 28704601

FI: 6,567

The combined therapy with chondroitin sulfate plus glucosamine sulfate or chondroitin sulfate plus glucosamine hydrochloride does not improve joint damage in an experimental model of knee osteoarthritis in rabbits

Roman-Blas JA, Mediero A, Tardío L, Portal-Nuñez S, Gratal P, Herrero-Beaumont G, Largo R.

European journal of pharmacology 2017 Jan 5 Volume: 794 Issue: Pages: 8-14.

PMID: 27845067

FI: 2,896

Combined Treatment With Chondroitin Sulfate and Glucosamine Sulfate Shows No Superiority Over Placebo for Reduction of Joint Pain and Functional Impairment in Patients With Knee Osteoarthritis: A Six-Month Multicenter, Randomized, Double-Blind, Placebo-Co

Roman-Blas JA, Castañeda S, Sánchez-Pernaute O, Largo R, Herrero-Beaumont G, CS/GS Combined Therapy Study Group..

Arthritis & rheumatology 2017 Jan Volume: 69 Issue: 1 Pages: 77-85.

PMID: 27477804

FI: 6,918

Molecular mechanisms in bone mechanotransduction

Maycas M, Esbrit P, Gortázar AR.

Histology and histopathology 2017 Aug Volume: 32 Issue: 8 Pages: 751-760.

PMID: 27981526

FI: 2,025

Oxidation inhibits PTH receptor signaling and trafficking

Ardura JA, Alonso V, Esbrit P, Friedman PA.

Biochemical and biophysical research communications 2017 Jan 22 Volume: 482 Issue: 4 Pages: 1019-1024.

PMID: 27908723

FI: 2,466

PTHrP-Derived Peptides Restore Bone Mass and Strength in Diabetic Mice: Additive Effect of Mechanical Loading

Maycas M, McAndrews KA, Sato AY, Pellegrini GG, Brown DM, Allen MR, Plotkin LI, Gortazar AR, Esbrit P, Bellido T.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2017 Mar Volume: 32 Issue: 3 Pages: 486-497.

PMID: 27683064

FI: 6,284

Parathyroid Hormone-Related Protein Protects Osteoblastic Cells From Oxidative Stress by Activation of MKP1 Phosphatase

Ardura JA, Portal-Núñez S, Castelbón-Calvo I, Martínez de Toda I, De la Fuente M, Esbrit P.

Journal of cellular physiology 2017 Apr Volume: 232 Issue: 4 Pages: 785-796.

PMID: 27357344

FI: 4,080


Proyectos, Contratos y EOs vigentes 2017


Fuentes de financiación públicas de proyectos que se están desarrollando en el IIS-FJD:


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REFERENCIA

TÍTULO PROYECTO

INVESTIGADOR PRINCIPAL

GRUPO

TIPO DE PROYECTO

CP15/00053

TENOFOVIR, AN ANTIRETROVIRAL DRUG FOR HIV, AND ITS EFFECT ON BONE HOMEOSTASIS. RELATION WITH THE PURINERGIC REGULATION OF BONE AND CARTILAGE.

MEDIERO MUÑOZ ARANZAZU

REUMATOLOGIA Y METABOLISMO OSEO

PROYECTO PÚBLICO COMPETITIVO

PI13/00570

CARACTERIZACIÓN TRASLACIONAL DE LA ARTROSIS OSTEOPORÓTICA: UN FENOTIPO DIFERENCIABLE EN LA CLÍNICA HUMANA Y EN SU TRATAMIENTO

HERRERO-BEAUMONT CUENCA GABRIEL

REUMATOLOGIA Y METABOLISMO OSEO

PROYECTO PÚBLICO COMPETITIVO

PI15/00340

EFECTO DE LOS FACTORES DE RIESGO METABÓLICOS Y ENDOCRINOS DE LA ARTROSIS SOBRE LOS MECANISMOS DE ACTIVACIÓN DE LA INMUNIDAD INNATA EN LA PROGRESIÓN DE ESTA ENFERMEDAD

LARGO CARAZO RAQUEL

REUMATOLOGIA Y METABOLISMO OSEO

PROYECTO PÚBLICO COMPETITIVO

PI15/00770

FACTORES PREDICTORES DE MANTENIMIENTO DE LA REMISIÓN CLÍNICA EN PACIENTES CON ARTRITIS PSORIÁSICA TRATADOS CON ANTI-TNF EN RÉGIMEN DE OPTIMIZACIÓN

NAREDO SÁNCHEZ ESPERANZA

REUMATOLOGIA Y METABOLISMO OSEO

PROYECTO PÚBLICO COMPETITIVO

PI16/00065

EL COMPONENTE INFLAMATORIO Y SU MODULACION EN EL REMODELADO MUSCULAR DE LA SARCOPENIA PRIMARIA GERIATRICA Y EN MODELOS ANIMALES DE ARTROSIS, ARTRITIS CRONICA Y ENVEJECIMIENTO

HERRERO-BEAUMONT CUENCA GABRIEL

REUMATOLOGIA Y METABOLISMO OSEO

PROYECTO PÚBLICO COMPETITIVO

PI16/00991

TENOFOVIR, FARMACO ANTIRETROVIRAL PARA VIH Y SUS EFECTOS EN HUESO Y MUSCULO. RELACION ENTRE EL SISTEMA PURINERGICO, EL HUESO, EL CARTILAGO Y EL MUSCULO

MEDIERO MUÑOZ ARANZAZU

REUMATOLOGIA Y METABOLISMO OSEO

PROYECTO PÚBLICO COMPETITIVO

12079/002

IMPACTO DE LA DIABETES MELLITUS TIPO 2 Y EL SINDROME METABOLICO EN LA EXPRESIÓN DE miRNAS RELACIONADOS CON LA ARTROSIS

LARGO CARAZO RAQUEL

REUMATOLOGIA Y METABOLISMO OSEO

FINANCIACIÓN PRIVADA

3579/005

CONVENIO DE COLABORACION ENTRE PFIZER Y LA FIIS-FJD PARA EL DESARROLLO DEL PROYECTO ROLE OF TOFACITINIB IN THE CONTROL OF CHOLESTEROL REVERSE TRANSPORT: UNDERSTANDING THE TOFACITINIB-INDUCED LIPID INCREASE ASSOCIATED TO CHRONIC ARTHRITIS.

HERRERO-BEAUMONT CUENCA GABRIEL

REUMATOLOGIA Y METABOLISMO OSEO

FINANCIACIÓN PRIVADA

38635/001

CONFIRMACION PAPEL DE DRAXINA Y EVALUACION PAPEL PEPTIDOS MIMETICOS DE DRAXINA EN LA DIFERENCIACION DE OSTEOCLASTOS. DRASIN AND MIMETIL COMPOUNDS.

MEDIERO MUÑOZ ARANZAZU

REUMATOLOGIA Y METABOLISMO OSEO

FINANCIACIÓN PRIVADA

4410/002

PROYECTO EDUCACIONAL BASADO EN EXPERIENCIAS CLÍNICAS EN EL MANEJO DE PACIENTES CON LUPUS ERITEMATOSO SISTEMICO Y BELIMUMAB

SANCHEZ PERNAUTE OLGA

REUMATOLOGIA Y METABOLISMO OSEO

FINANCIACIÓN PRIVADA

4410/003

BECA SORCOM MSD 2016 PARA REUMATOLOGOS DE MAS DE DIEZ AÑOS. PROYECTO. EVALUACION SISTEMATIZADA DE LA GRAVEDAD DE LA ISQUEMIA DIGITAL ASOCIADA AL FENOMENO DE RAYNAUD: APROXIMACION A UNA MEDIDA DE DESENLACE PARA EL SEGUIMIENTO.

SANCHEZ PERNAUTE OLGA

REUMATOLOGIA Y METABOLISMO OSEO

PROYECTO COMPETITIVO PRIVADO

5283/006

PRESTACIÓN DE SERVICIOS PARA LLEVAR A CABO UN ESTUDIO MULTICENTRICO CUYO FIN ES SOMETER A EVALUACION CLINICA EL FARMACO DEL PROMOTOR, BI 1361849

LARGO CARAZO RAQUEL

REUMATOLOGIA Y METABOLISMO OSEO

FINANCIACIÓN PRIVADA

3579/006

CONVENIO DE COLABORACION ENTRE LA FUAM Y LA FIIS-FJD PARA EL DESARROLLO DEL PROYECTO EL COMPONENTE INFLAMATORIO Y SU MODULACIÓN EN EL REMODELADO MUSCULAR DE LA SARCOPENIA PRIMARIA GERIÁTRICA Y EN MODELOS ANIMALES DE ARTROSIS, ARTRITIS CRÓNICA Y ENVEJECIM

HERRERO-BEAUMONT CUENCA GABRIEL

REUMATOLOGIA Y METABOLISMO OSEO

FINANCIACIÓN PRIVADA

3579/007

HAND OSTEOARTHRITIS-EULAR TASK FORCE- LEAD BY MARGREET KLOPENBURG

HERRERO-BEAUMONT CUENCA GABRIEL

REUMATOLOGIA Y METABOLISMO OSEO

FINANCIACIÓN PRIVADA

EO 69/2017_FJD

EVIDENCE-BASED FEASIBILITY (EBF) OF ACTELION'S PLANNED PHASE IIB PROTOCOL FOR CENERIMOD IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

SANCHEZ PERNAUTE OLGA

REUMATOLOGIA Y METABOLISMO OSEO

ESTUDIOS OBSERVACIONALES

EOH 2017/51_FJD

CARGA DE LA ENFERMEDAD DE LA HIPOFOSFATEMIA LIGADA AL CROMOSOMA X. XLH-QoL

DIAZ CURIEL MANUEL

REUMATOLOGIA Y METABOLISMO OSEO

ESTUDIOS OBSERVACIONALES


EECC vigentes 2017


Número EudraCT

Título

FASE

MC

INT

Investigador Principal

2012-003686-17

"ESTUDIO FASE 3 MULTICENTRICO PARA EVALUAR LA SEGURIDAD Y EFICACIA DE BARICITINIB EN PACIENTES CON ARTRITIS REUMATOIDE"

II/III

SI

SI

PEREZ ESTEBAN SILVIA

2014-000358-13

"ESTUDIO DE FASE 3B/4, ALEATORIZADO, DOBLE CIEGO DE 5 MG DE TOFACITINIB CON Y SIN METOTREXATO EN COMPARACIÓN CON ADALIMUMAB CON METOTREXATO EN PACIENTES CON ARTRITIS REUMATOIDE ACTIVA DE MODERADA A GRAVE"

III/IV

SI

SI

PEREZ ESTEBAN SILVIA

2013-004508-21

ESTUDIO DE FASE 3, ALEATORIZADO, DOBLE CIEGO, CONTROLADO CON PLACEBO, MULTICÉNTRICO DE LA SEGURIDAD Y EFICACIA ANALGÉSICAS DE LA ADMINISTRACIÓN SUBCUTÁNEA DE TANEZUMAB EN SUJETOS CON ARTROSIS DE CADERA O DE RODILLA

III

SI

SI

GODO BRITO JAVIER RODOLFO

2015-002887-17

ESTUDIO FASE 2, ALEATORIZADO, MULTICÉNTRICO, DOBLE CIEGO, DE DETERMINACIÓN DE DOSIS, CONTROLADO CON PLACEBO Y CON DISEÑO ADAPTATIVO PARA EVALUAR LA EFICACIA Y SEGURIDAD/FARMACOCINÉTICA DE BMS?986142 EN SUJETOS CON ARTRITIS REUMATOIDE DE MODERADA A GRAVE Y RESPUESTA INADECUADA A METOTREXATO CON O SIN INHIBIDORES DEL TNF

II

SI

SI

RECUERO DIAZ SHEILA

2016-000972-91

ESTUDIO MULTICÉNTRICO, ALEATORIZADO, DOBLE CIEGO, CONTROLADO CON PLACEBO PARA DEMOSTRAR LA EFICACIA DE SECUKINUMAB SUBCUTÁNEO HASTA 1 AÑO EN EL TRATAMIENTO DE LA ENTESITIS DEL TENDÓN DE AQUILES EN PACIENTES ADULTOS CON ARTRITIS PSORIÁSICA (APS) ACTIVA Y ESPONDILOARTRITIS AXIAL (ESPA AXIAL) (ACHILLES)

III

SI

SI

GODO BRITO JAVIER RODOLFO

2015-002394-38

ESTUDIO MULTICÉNTRICO DE 52 SEMANAS PARA DETERMINAR EL CURSO TEMPORAL DE LA RESPUESTA A SECUKINUMAB EN LA INFLAMACIÓN ARTICULAR UTILIZANDO ULTRASONOGRAFÍA DOPPLER DE PODER EN PACIENTES CON ARTRITIS PSORIÁSICA ACTIVA

III

SI

SI

NAREDO SÁNCHEZ ESPERANZA

2016-000814-31

MAXIMISE (TRATAMIENTO DE LAS MANIFESTACIONES AXIALES EN LA ARTRITIS PSORIÁSICA CON SECUKINUMAB), ESTUDIO MULTICÉNTRICO, ALEATORIZADO, DOBLE CIEGO, CONTROLADO CON PLACEBO, DE 52 SEMANAS DE SEGUIMIENTO PARA EVALUAR LA EFICACIA Y SEGURIDAD DE SECUKINUMAB 150 MG O 300 MG S.C. EN PACIENTES CON ARTRITIS PSORIÁSICA ACTIVA Y AFECCIÓN DEL ESQUELETO AXIAL QUE NO RESPONDAN ADECUADAMENTE A ANTIINFLAMATORIOS NO ESTEROIDEOS (AINES)

III

SI

SI

GODO BRITO JAVIER RODOLFO


Patentes


1. Título: "Biomaterial con osteostatina para regeneración ósea e ingeniería tisular"

Nº solicitud: P201031193

Entidades titulares: UCM (45%), IIS-FJD (33%), UAH (22%).

Inventores: María Vallet Regí, Antonio Jesús Salinas Sánchez, Miguel Manzano García, Juan Carlos Doadrio Villarejo, Pedro Esbrit Argüelles, Enrique Gómez Barrena, Daniel Lozano Borregón, María Julia Buján Varela, Natalio García Hondurilla.


2. Título: "Uso de 6-SHOGAOL para la fabricación de un medicamento para el tratamiento de la osteoporosis"

Nº solicitud: P201430853

Entidades titulares: IIS-FJD (100%)

Inventores: Raquel Largo Carazo, Gabriel Herrero-Beaumont Cuenca.


3. Título: "Uso de la osteostatina en la preparación de un medicamento para el tratamiento de la artrosis"

Nº solicitud: P201531318

Entidades titulares: IIS-FJD (100%)

Inventores: Pedro Esbrit Arguelles, Sergio Portal Nuñez, Gabriel Herrero-Beaumont Cuenca, Raquel Largo Carazo.