Alergia e Inmunología

Resumen de actividad

La actividad clínica e investigadora del grupo se centra en el estudio de enfermedades con etiopatología inmunológica (alérgicas y cardiovasculares principalmente) y en la identificación de biomarcadores de diagnóstico/pronóstico mediante estrategias ómicas, particularmente en el área cardio-renal. Tanto en las patologías inflamatorias agudas (anafilaxia), como crónicas (asma y remodelado de la pared vascular), se estudian los mecanismos inmunopatogénicos y de señalización asociados a la enfermedad y el desarrollo de herramientas que mejoren el diagnóstico y la terapia de las mismas.

Contribuciones a la sociedad

En la última década, su contribución a la sociedad se cimenta en la publicación de más de 600 artículos originales y revisiones en revistas de impacto científico, desarrollo de 20 guías de actuación/manejo clínico y 2 patentes. Su implicación social lleva a estar en contacto con distintas asociaciones de pacientes. En relación a esto, se han elaborado vídeos divulgativos, y participado en medios de comunicación por su contribución como expertos a la mejora de la enfermedad.

Colaboraciones

El grupo es miembro de las distintas sociedades españolas y europeas de alergia, inmunología, enfermedad cardiovascular y patología renal, e incluso forma parte del comité ejecutivo de EAACI. A nivel nacional, forma parte de CIBERES y RICORS2040 y se establecen distintas colaboraciones intra y extramurales (Ej, CIBERES, ARADyAL, GEIVEX, PROTEORED, SESMET) con distintos especialistas de renombre en el campo. A nivel internacional, hay numerosas colaboraciones estrechamente establecidas. Todos los responsables de grupo participan como editores de prestigiosas revistas líderes en el campo.

Tesis doctorales

Relación de publicaciones ordenadas por fecha de publicación

Anaphylaxis after mango fruit intake. Identification of new allergens.

Ortega-Martín L, Sastre B, Rodrigo-Muñoz JM, Cañas JA, Valverde-Monge M, Del Pozo V

Journal of investigational allergology &clinical immunology. 2021 Nov 16;0.

PMID: 34783658

FI: 7,033

Evaluation of fractional exhaled nitric oxide during SARS-CoV-2 infection.

Betancor D, Valverde-Mongue M, Gomez-Lopez A, Barroso B, Ruete L, Olaguibel JM, Sastre J

Journal of investigational allergology &clinical immunology. 2021 Nov 10;0.

PMID: 34755657

FI: 7,033

Early renal and vascular damage within the normoalbuminuria condition.

Santiago-Hernandez A, Martin-Lorenzo M, Martínez PJ, Gómez-Serrano M, Lopez JA, Cannata P, Esteban V, Heredero A, Aldamiz-Echevarria G, Vázquez J, Ruiz-Hurtado G, Barderas MG, Segura J, Ruilope LM, Alvarez-Llamas G

Journal of hypertension. 2021 Nov 1;39(11):2220-2231.

PMID: 34261953

FI: 4,844

Bioethical Concerns During the COVID-19 Pandemic: What Did Healthcare Ethics Committees and Institutions State in Spain?

Ruiz-Hornillos J, Hernández Suárez P, Marín Martínez JM, de Miguel Beriain Í, Nieves Vázquez MA, Albert M, Herrera Abián M, Pacheco-Martínez PA, Trasmontes V, Guillén-Navarro E

Frontiers in public health. 2021 Oct 13;9:737755.

PMID: 34722445

FI: 3,709

Role of miR-185-5p as modulator of periostin synthesis and smooth muscle contraction in asthma.

Rodrigo-Muñoz JM, Cañas JA, Sastre B, Gil-Martínez M, García Latorre R, Sastre J, Del Pozo V

Journal of cellular physiology. 2021 Oct 26.

PMID: 34698372

FI: 6,384

Anxiety and BMI affect asthma control: data from a prospective Spanish cohort.

Baptista-Serna L, Rodrigo-Muñoz JM, Mínguez P, Valverde-Monge M, Arismendi E, Barranco P, Barroso B, Bobolea I, Cañas JA, Cárdaba B, Cruz MJ, Curto E, Domínguez J, García-Latorre R, González-Barcala FJ, Martínez-Rivera C, Mullol J, Muñoz X, Olaguibel JM, Picado C, Plaza V, Quirce S, Rial MJ, Sastre B, Soto L, Valero A, Pozo VD, Sastre J.

J Allergy Clin Immunol Pract. 2021 Oct 18:S2213-2198(21)01130-2

PMID: 34673289

FI: 8,861

Nonasthmatic Eosinophilic Bronchitis and Asthma Development: analysis of biomarkers.

Villalobos-Violan V, Betancor D, Mahíllo-Fernández I, Sastre J

Journal of investigational allergology &clinical immunology. 2021 Oct 15;0.

PMID: 34661536

FI: 7,033

Machine learning for grading and prognosis of esophageal dysplasia using mass spectrometry and histological imaging.

Beuque M, Martin-Lorenzo M, Balluff B, Woodruff HC, Lucas M, de Bruin DM, van Timmeren JE, Boer OJ, Heeren RM, Meijer SL, Lambin P

Computers in biology and medicine. Epub 2021 Oct 4. 2021 Nov;138:104918.

PMID: 34638018

FI: 4,589

High SARS-CoV-2 viral load is associated with a worse clinical outcome of COVID-19 disease.

Soria ME, Cortón M, Martínez-González B, Lobo-Vega R, Vázquez-Sirvent L, López-Rodríguez R, Almoguera B, Mahillo I, Mínguez P, Herrero A, Taracido JC, Macías-Valcayo A, Esteban J, Fernandez-Roblas R, Gadea I, Ruíz-Hornillos J, Ayuso C, Perales C

Access microbiology. 2021 Sep 21;3(9):000259.

PMID: 34712904

FI: 0

Editorial: Impact of System Biology and Molecular Medicine on the Management of Complex Immune Mediated Respiratory Diseases.

Cárdaba B and Pelaia G

Frontiers in medicine. 2021 Sep 8;8:745739.

PMID: 34568397

FI: 5,093

Serum microRNAs catalog asthmatic patients by phenotype.

Gil-Martínez M, Rodrigo-Muñoz JM, Sastre B, Cañas JA, García-Latorre R, Redondo N, de la Fuente L, Mínguez P, Mahíllo-Fernández I, Sastre J, Quirce S, Caballero ML, Olaguibel JM, Pozo V

Journal of investigational allergology &clinical immunology. 2021 Sep 6;0

PMID: 34489228

FI: 7,033

Exploring adherence to treatment in nasal polyposis.

Valverde-Monge M, Barroso B, Ortega-Martin L, Betancor D, Santillan J, Villacampa JM, Sastre J

Journal of investigational allergology &clinical immunology. 2021 Sep 3;0.

PMID: 34489223

FI: 7,033

Skin lesions, weakness, and axillary adenopathies in a 44-year-old woman.

Rueda-Camino JA, Robles-Barrena I, Vegas-Sánchez MC

European journal of internal medicine. Epub 2021 Sep 4. 2021 Nov;93:95-96.

PMID: 34489163

FI: 4,624

Metoprolol in Critically Ill Patients With COVID-19.

Clemente-Moragón A, Martínez-Milla J, Oliver E, Santos A, Flandes J, Fernández I, Rodríguez-González L, Serrano Del Castillo C, Ioan AM, López-Álvarez M, Gómez-Talavera S, Galán-Arriola C, Fuster V, Pérez-Calvo C, Ibáñez B

Journal of the American College of Cardiology. 2021 Sep 7;78(10):1001-1011.

PMID: 34474731

FI: 24,093

Coeliac Disease in Elderly Patients: Value of Coeliac Lymphogram for Diagnosis.

Fernández-Bañares F, Farrais S, Planella M, Melero J, López-Palacios N, Vivas S, Fernández-Salazar L, Lanzarote AP, Ruiz-Ramírez P, Aguilar-Criado M, Vidal J, Esquerda A, Serrano C, Núñez C

Nutrients. 2021 Aug 27;13(9):2984.

PMID: 34578861

FI: 5,719

Metabolic Alterations Identified in Urine, Plasma and Aortic Smooth Muscle Cells Reflect Cardiovascular Risk in Patients with Programmed Coronary Artery Bypass Grafting.

Santiago-Hernandez A, Martinez PJ, Agudiez M, Heredero A, Gonzalez-Calero L, Yuste-Montalvo A, Esteban V, Aldamiz-Echevarria G, Martin-Lorenzo M, Alvarez-Llamas G

Antioxidants. 2021 Aug 27;10(9):1369.

PMID: 34573001

FI: 6,313

Elevated levels of arginase activity are related to inflammation in patients with COPD exacerbation.

Rodríguez-Guzmán MJ, Peces-Barba Romero G, Pérez Rial S, Serrano Del Castillo C, Palomero Rodríguez MÁ, Mahillo-Fernandez I, Villar-Álvarez F

BMC pulmonary medicine. 2021 Aug 21;21(1):271.

PMID: 34418988

FI: 3,317

Characterization of anaphylaxis reveals different metabolic changes depending on severity and triggers.

Perales-Chorda C, Obeso D, Twomey L, Rojas-Benedicto A, Puchades-Carrasco L, Roca M, Pineda-Lucena A, Laguna JJ, Barbas C, Esteban V, Martí-Garrido J, Ibañez-Echevarria E, López-Salgueiro R, Barber D, Villaseñor A, Hernández Fernández de Rojas D

Clinical and experimental allergy. Epub 2021 Aug 2. 2021 Oct;51(10):1295-1309.

PMID: 34310748

FI: 5,018

Peptide Allergen Immunotherapy: A New Perspective in Olive-Pollen Allergy.

David Calzada, Lucía Cremades-Jimeno, María López-Ramos, Blanca Cárdaba

Pharmaceutics. 2021 Jul 2;13(7):1007.

PMID: 34371699

FI: 6,321

TCA Cycle and Fatty Acids Oxidation Reflect Early Cardiorenal Damage in Normoalbuminuric Subjects with Controlled Hypertension.

Santiago-Hernandez A, Martin-Lorenzo M, Martin-Blazquez A, Ruiz-Hurtado G, Barderas MG, Segura J, Ruilope LM, Alvarez-Llamas G

Antioxidants. 2021 Jul 9;10(7):1100.

PMID: 34356333

FI: 6,313

The excellent biocompatibility and negligible immune response of the titanium heterometallic MOF MUV-10.

Lázaro IA, Rodrigo-Muñoz JM, Sastre B, Ángel MR, Martí-Gastaldo C, Del Pozo V

Journal of materials chemistry. B. Epub 2021 Jul 20. 2021 Aug 21;9(31):6144-6148.

PMID: 34286816

FI: 6,331

Upadacitinib-induced remission of allergic asthma: A case report.

Betancor D, Valverde-Monge M, Sastre J

The journal of allergy and clinical immunology. In practice. Epub 2021 Jul 16. 2021 Nov;9(11):4162-4163.

PMID: 34280588

FI: 8,861

Non-syndromic thoracic aortic aneurysm: cellular and molecular insights.

Martin-Blazquez A, Heredero A, Aldamiz-Echevarria G, Martin-Lorenzo M, Alvarez-Llamas G

The Journal of pathology. 2021 Jul;254(3):229-238.

PMID: 33885146

FI: 7,996

Proteomic and Biological Analysis of an In Vitro Human Endothelial System in Response to Drug Anaphylaxis.

Yuste-Montalvo A, Fernandez-Bravo S, Oliva T, Pastor-Vargas C, Betancor D, Goikoetxea MJ, Laguna JJ, López JA, Alvarez-Llamas G, Cuesta-Herranz J, Martin-Lorenzo M, Esteban V

Frontiers in immunology. 2021 Jun 25;12:692569.

PMID: 34248989

FI: 7,561

Emerging Evidence for Pleiotropism of Eosinophils.

Rodrigo-Muñoz JM, Gil-Martínez M, Sastre B, Del Pozo V

International journal of molecular sciences. 2021 Jun 30;22(13):7075.

PMID: 34209213

FI: 5,924

LTP Allergy Follow-Up Study: Development of Allergy to New Plant Foods 10 Years Later.

Betancor D, Gomez-Lopez A, Villalobos-Vilda C, Nuñez-Borque E, Fernández-Bravo S, De Las Heras Gozalo M, Pastor-Vargas C, Esteban V, Cuesta-Herranz J

Nutrients. 2021 Jun 24;13(7):2165.

PMID: 34202484

FI: 5,719

Urinary Spermidine Predicts and Associates with In-Hospital Acute Kidney Injury after Cardiac Surgery.

Martin-Lorenzo M, Ramos-Barron A, Gutierrez-Garcia P, Martin-Blazquez A, Santiago-Hernandez A, Rodrigo Calabia E, Gomez-Alamillo C, Alvarez-Llamas G

Antioxidants. 2021 Jun 2;10(6):896.

PMID: 34199603

FI: 6,313

Eosinophils and Chronic Respiratory Diseases in Hospitalized COVID-19 Patients.

Valverde-Monge M, Cañas JA, Barroso B, Betancor D, Ortega-Martin L, Gómez-López A, Rodríguez-Nieto MJ, Mahíllo-Fernández I, Sastre J, Del Pozo V

Frontiers in immunology. 2021 Jun 2;12:668074.

PMID: 34149705

FI: 7,561

ARIA-EAACI care pathways for allergen immunotherapy in respiratory allergy.

Bousquet J, Pfaar O, Agache I, Bedbrook A, Akdis CA, Canonica GW, Chivato T, Al-Ahmad M, Abdul Latiff AH, Ansotegui IJ, Bachert C, Baharuddin A, Bergmann KC, Bindslev-Jensen C, Bjermer L, Bonini M, Bosnic-Anticevich S, Bosse I, Brough HA, Brussino L, Calderon MA, Caraballo L, Cardona V, Carreiro-Martins P, Casale T, Cecchi L, Cepeda Sarabia AM, Chkhartishvili E, Chu DK, Cirule I, Cruz AA, Czarlewski W, Del Giacco S, Demoly P, Devillier P, Dokic D, Durham SL, Ebisawa M, El-Gamal Y, Emuzyte R, Gamkrelidze A, Fauquert JL, Fiocchi A, Fokkens WJ, Fonseca JA, Fontaine JF, Gawlik R, Gelincik A, Gemicioglu B, Gereda JE, Gerth van Wijk R, Gomez RM, Gotua M, Grisle I, Guzmán MA, Haahtela T, Halken S, Heffler E, Hoffmann-Sommergruber K, Hossny E, Hrubiško M, Irani C, Ivancevich JC, Ispayeva Z, Julge K, Kaidashev I, Kalayci O, Khaitov M, Klimek L, Knol E, Kowalski ML, Kraxner H, Kull I, Kuna P, Kvedariene V, Kritikos V, Lauerma A, Lau S, Laune D, Levin M, Larenas-Linnemann DE, Lodrup Carlsen KC, Lombardi C, Lourenço OM, Mahboub B, Malling HJ, Manning P, Marshall GD, Melén E, Meltzer EO, Miculinic N, Milenkovic B, Moin M, Montefort S, Morais-Almeida M, Mortz CG, Mösges R, Mullol J, Namazova Baranova L, Neffen H, Nekam K, Niedoszytko M, Odemyr M, O'Hehir RE, Ollert M, O'Mahony L, Ohta K, Okamoto Y, Okubo K, Pajno GB, Palomares O, Palkonen S, Panzner P, G Papadopoulos N, Park HS, Passalacqua G, Patella V, Pawankar R, Pham-Thi N, Plavec D, Popov TA, Recto M, Regateiro FS, Riggioni C, Roberts G, Rodriguez-Gonzales M, Rosario N, Rottem M, Rouadi PW, Ryan D, Samolinski B, Sanchez-Borges M, Serpa FS, Sastre J, Scadding GK, Shamji MH, Schmid-Grendelmeier P, Schünemann HJ, Sheikh A, Scichilone N, Sisul JC, Sofiev M, Solé D, Sooronbaev T, Soto-Martinez M, Soto-Quiros M, Sova M, Schwarze J, Skypala I, Suppli-Ulrik C, Taborda-Barata L, Todo-Bom A, Torres MJ, Valentin-Rostan M, Tomazic PV, Valero A, Toppila-Salmi S, Tsiligianni I, Untersmayr E, Urrutia-Pereira M, Valiulis A, Valovirta E, Vandenplas O, Ventura MT, Vichyanond P, Wagenmann M, Wallace D, Walusiak-Skorupa J, Wang Y, Waserman S, Wong GW, Yorgancioglu A, Yusuf OM, Zernotti M, Zhang L, Zidarn M, Zuberbier T, Jutel M

Clinical and translational allergy. 2021 Jun 9;11(4):e12014.

PMID: 34136127

FI: 5,871

Anaphylaxis Due to Silene Vulgaris Ingestion.

Haroun-Díaz E, Torres I, Blanca-López N, Somoza ML, Martín-Pedraza L, Ruano FJ, Vázquez de la Torre M, Cuesta-Herranz J, Bartolomé Zavala B, Blanca M, Canto Díez G

Journal of investigational allergology &clinical immunology. 2021 Jun 4;0.

PMID: 34085937

FI: 7,033

Seed Storage Proteins, 2S Albumin And 11S Globulin, Associated to Severe Allergic Reactions after Flaxseed Intake.

Bueno-Díaz C, Biserni C, Martín-Pedraza L, de Las Heras M, Blanco C, Vázquez-Cortés S, Fernández-Rivas M, Batanero E, Cuesta-Herranz J, Villalba M

Journal of investigational allergology &clinical immunology. 2021 Jun 4;0.

PMID: 34085936

FI: 7,033

Sarcoplasmic calcium-binding protein and alcohol dehydrogenase, new occupational allergens in the fruit fly Drosophila melanogaster.

Betancor D, López-Matas MA, González-Ruiz A, Martín-López L, Carnés J, Fernández-Nieto MDM

Clinical and experimental allergy. Epub 2021 Jun 9. 2021 Oct;51(10):1387-1390.

PMID: 33998742

FI: 5,018

Analysis of Global Oxidative Status Using Multimarker Scores Reveals a Specific Association Between Renal Dysfunction and Diuretic Therapy in Older Adults.

Rodríguez-Sánchez E, Navarro-García JA, Aceves-Ripoll J, González-Lafuente L, Corbacho-Alonso N, Baldan-Martín M, Madruga F, Alvarez-Llamas G, Barderas MG, Ruilope LM, Ruiz-Hurtado G

The journals of gerontology. Series A, Biological sciences and medical sciences. 2021 Jun 14;76(7):1198-1205.

PMID: 33423057

FI: 6,053

Characterization of Relevant Biomarkers for the Diagnosis of Food Allergies: An Overview of the 2S Albumin Family.

Bueno-Díaz C, Martín-Pedraza L, Parrón J, Cuesta-Herranz J, Cabanillas B, Pastor-Vargas C, Batanero E, Villalba M

Foods. 2021 May 29;10(6):1235.

PMID: 34072292

FI: 4,35

Molecular allergology and its impact in specific allergy diagnosis and therapy.

Barber D, Diaz-Perales A, Escribese MM, Kleine-Tebbe J, Matricardi P, Ollert M, Santos AF, Sastre J

Allergy. 2021 May 31.

PMID: 34057744

FI: 13,146

Cardiovascular risk stratification based on oxidative stress for early detection of pathology.

Corbacho-Alonso N, Baldan-Martin M, Lopez JA, Rodriguez-Sanchez E, Martinez PJ, Mourino-Alvarez L, Sastre-Oliva T, Cabrera M, Calvo E, Padial LR, Vazquez J, Vivanco F, Alvarez-Llamas G, Ruiz-Hurtado G, Ruilope LM, Barderas MG

Antioxidants & redox signaling. 2021 May 26.

PMID: 34036803

FI: 8,401

The age again in the eye of the COVID-19 storm: evidence-based decision making.

Martín MC, Jurado A, Abad-Molina C, Orduña A, Yarce O, Navas AM, Cunill V, Escobar D, Boix F, Burillo-Sanz S, Vegas-Sánchez MC, Jiménez-de Las Pozas Y, Melero J, Aguilar M, Sobieschi OI, López-Hoyos M, Ocejo-Vinyals G, San Segundo D, Almeida D, Medina S, Fernández L, Vergara E, Quirant B, Martínez-Cáceres E, Boiges M, Alonso M, Esparcia-Pinedo L, López-Sanz C, Muñoz-Vico J, López-Palmero S, Trujillo A, Álvarez P, Prada Á, Monzón D, Ontañón J, Marco FM, Mora S, Rojo R, González-Martínez G, Martínez-Saavedra MT, Gil-Herrera J, Cantenys-Molina S, Hernández M, Perurena-Prieto J, Rodríguez-Bayona B, Martínez A, Ocaña E, Molina J

Immunity &ageing. 2021 May 20;18(1):24.

PMID: 34016150

FI: 6,4

Allergy to orange with cystatine-like protein as one of its allergens.

Solórzano-Zepeda C, Pérez-Allegue I, Pastor-Vargas C, Bartolomé-Zavala B, González-de-Olano D

Annals of allergy, asthma &immunology. 2021 May 7;S1081-1206(21)00341-0.

PMID: 33971354

FI: 6,347

Allergen Profile of London Plane Tree Pollen: Clinical and Molecular Pattern in Central Spain.

Nuñez-Borque E, Betancor D, Fernández-Bravo S, Gómez-Cardeñosa A, Esteban V, Garrido-Arandia M, de Las Heras M, Pastor-Vargas C, Cuesta-Herranz J

Journal of investigational allergology &clinical immunology. 2021 May 5;0.

PMID: 33949950

FI: 7,033

Differentiation of COVID-19 signs and symptoms from allergic rhinitis and common cold: An ARIA-EAACI-GA² LEN consensus.

Hagemann J, Onorato GL, Jutel M, Akdis CA, Agache I, Zuberbier T, Czarlewski W, Mullol J, Bedbrook A, Bachert C, Bennoor KS, Bergmann KC, Braido F, Camargos P, Caraballo L, Cardona V, Casale T, Cecchi L, Chivato T, Chu DK, Cingi C, Correia-de-Sousa J, Del Giacco S, Dokic D, Dykewicz M, Ebisawa M, El-Gamal Y, Emuzyte R, Fauquert JL, Fiocchi A, Fokkens WJ, Fonseca JA, Gemicioglu B, Gomez RM, Gotua M, Haahtela T, Hamelmann E, Iinuma T, Ivancevich JC, Jassem E, Kalayci O, Kardas P, Khaitov M, Kuna P, Kvedariene V, Larenas-Linnemann DE, Lipworth B, Makris M, Maspero JF, Miculinic N, Mihaltan F, Mohammad Y, Montefort S, Morais-Almeida M, Mösges R, Naclerio R, Neffen H, Niedoszytko M, O'Hehir RE, Ohta K, Okamoto Y, Okubo K, Panzner P, Papadopoulos NG, Passalacqua G, Patella V, Pereira A, Pfaar O, Plavec D, Popov TA, Prokopakis EP, Puggioni F, Raciborski F, Reijula J, Regateiro FS, Reitsma S, Romano A, Rosario N, Rottem M, Ryan D, Samolinski B, Sastre J, Solé D, Sova M, Stellato C, Suppli-Ulrik C, Tsiligianni I, Valero A, Valiulis A, Valovirta E, Vasankari T, Ventura MT, Wallace D, Wang Y, Williams S, Yorgancioglu A, Yusuf OM, Zernotti M, Bousquet J, Klimek L

Allergy. Epub 2021 May 14. 2021 Aug;76(8):2354-2366.

PMID: 33730365

FI: 13,146

IL-6-based mortality prediction model for COVID-19: Validation and update in multicenter and second wave cohorts.

Utrero-Rico A, Ruiz-Hornillos J, González-Cuadrado C, Rita CG, Almoguera B, Minguez P, Herrero-González A, Fernández-Ruiz M, Carretero O, Taracido-Fernández JC, López-Rodriguez R, Corton M, Aguado JM, Villar LM, Ayuso-García C, Paz-Artal E, Laguna-Goya R

The Journal of allergy and clinical immunology. 2021 May;147(5):1652-1661.e1.

PMID: 33662370

FI: 10,793

Phenotypes of occupational asthma defined with induced sputum after specific inhalation challenge.

Migueres, N; Vandenplas, O; Suojalehto, H; Walusiak-Skorupa, J; Munoz, X; Sastre, J; Merget, R; Moscato, G; Quirce, S; Meyer, N; Godet, J; de Blay, F

Revue Francaise D Allergologie. 2021 May;61(4):223-225.

PMID:

FI: 0,288

Prioritizing Molecular Biomarkers in Asthma and Respiratory Allergy Using Systems Biology.

Cremades-Jimeno L, de Pedro MÁ, López-Ramos M, Sastre J, Mínguez P, Fernández IM, Baos S, Cárdaba B.

Frontiers in immunology. 2021 Apr 15;12:640791.

PMID: 33936056

FI: 7,561

In Vitro Investigation of Vascular Permeability in Endothelial Cells from Human Artery, Vein and Lung Microvessels at Steady-State and Anaphylactic Conditions.

Callesen KT, Yuste-Montalvo A, Poulsen LK, Jensen BM, Esteban V

Biomedicines. 2021 Apr 19;9(4):439.

PMID: 33921871

FI: 6,081

Non-infectious Uveitis as a Manifestation of the Immune Reconstitution Inflammatory Syndrome in Patients Infected by HIV.

Hernanz I, Alvear-Torres A, Serrano Del Castillo C, Sánchez-Pernaute O, Recuero S, Romero-Bueno F, Muñoz N, Carreño E

Ocular immunology and inflammation. 2021 Apr 28;1-5.

PMID: 33908843

FI: 3,07

Increased miR-21-3p and miR-487b-3p serum levels during anaphylactic reaction in food allergic children.

Nuñez-Borque E, Fernandez-Bravo S, Rodriguez Del Rio P, Alwashali EM, Lopez-Dominguez D, Gutierrez-Blazquez MD, Laguna JJ, Tome-Amat J, Gallego-Delgado J, Gomez-Lopez A, Betancor D, Cuesta-Herranz J, Ibañez-Sandin MD, Benito-Martin A, Esteban V

Pediatric allergy and immunology. 2021 Apr 19.

PMID: 33876465

FI: 6,377

Management of anaphylaxis due to COVID-19 vaccines in the elderly.

Bousquet J, Agache I, Blain H, Jutel M, Ventura MT, Worm M, Del Giacco S, Benetos A, Bilo MB, Czarlewski W, Abdul Latiff AH, Al-Ahmad M, Angier E, Annesi-Maesano I, Atanaskovic-Markovic M, Bachert C, Barbaud A, Bedbrook A, Bennoor KS, Berghea EC, Bindslev-Jensen C, Bonini S, Bosnic-Anticevich S, Brockow K, Brussino L, Camargos P, Canonica GW, Cardona V, Carreiro-Martins P, Carriazo A, Casale T, Caubet JC, Cecchi L, Cherubini A, Christoff G, Chu DK, Cruz AA, Dokic D, El-Gamal Y, Ebisawa M, Eberlein B, Farrell J, Fernandez-Rivas M, Fokkens WJ, Fonseca JA, Gao Y, Gavazzi G, Gawlik R, Gelincik A, Gemicio?lu B, Gotua M, Guérin O, Haahtela T, Hoffmann-Sommergruber K, Hoffmann HJ, Hofmann M, Hrubisko M, lenaIllario M, Irani C, Ispayeva Z, Ivancevich JC, Julge K, Kaidashev I, Khaitov M, Knol E, Kraxner H, Kuna P, Kvedariene V, Lauerma A, Le LT, Le Moing V, Levin M, Louis R, Lourenco O, Mahler V, Martin FC, Matucci A, Milenkovic B, Miot S, Montella E, Morais-Almeida M, Mortz CG, Mullol J, Namazova-Baranova L, Neffen H, Nekam K, Niedoszytko M, Odemyr M, O'Hehir RE, Okamoto Y, Ollert M, Palomares O, Papadopoulos NG, Panzner P, Passalacqua G, Patella V, Petrovic M, Pfaar O, Pham-Thi N, Plavec D, Popov TA, Recto MT, Regateiro FS, Reynes J, Roller-Winsberger RE, Rolland Y, Romano A, Rondon C, Rottem M, Rouadi PW, Salles N, Samolinski B, Santos AF, Serpa FS, Sastre J, Schols JMGA, Scichilone N, Sediva A, Shamji MH, Sheikh A, Skypala I, Smolinska S, Sokolowska M, Sousa-Pinto B, Sova M, Stelmach R, Sturm G, Suppli Ulrik C, Todo-Bom AM, Toppila-Salmi S, Tsiligianni I, Torres M, Untersmayr E, Urrutia Pereira M, Valiulis A, Vitte J, Vultaggio A, Wallace D, Walusiak-Skorupa J, Wang DY, Waserman S, Yorgancioglu A, Yusuf OM, Zernotti M, Zidarn M, Chivato T, Akdis CA, Zuberbier T, Klimek L

Allergy. 2021 Apr 2;10.1111/all.14838.

PMID: 33811358

FI: 13,146

CCN2 (Cellular Communication Network Factor 2) Deletion Alters Vascular Integrity and Function Predisposing to Aneurysm Formation.

Rodrigues-Díez RR, Tejera-Muñoz A, Esteban V, Steffensen LB, Rodrigues-Díez R, Orejudo M, Rayego-Mateos S, Falke LL, Cannata-Ortiz P, Ortiz A, Egido J, Mallat Z, Briones Ana M, Bajo MA, Goldschmeding R, Ruiz-Ortega M

Hypertension. Epub 2021 Dec 30. 2022 Mar;79(3):e42-e55.

PMID: 35138869

FI: 10,19

Clinical and inflammatory characteristics of patients with asthma in the Spanish MEGA project cohort.

Rial MJ, Álvarez-Puebla MJ, Arismendi E, Caballero ML, Cañas JA, Cruz MJ, González-Barcala FJ, Luna JA, Martínez-Rivera C, Mullol J, Muñoz X, Olaguibel JM, Picado C, Plaza V, Quirce S, Romero-Mesones C, Salgado FJ, Sastre B, Soto-Retes L, Valero A, Valverde M, Sastre J, Pozo VD

Clinical and translational allergy. 2021 Mar;11(1):e12001.

PMID: 33900052

FI: 5,871

Changes in Serum MicroRNAs after Anti-IL-5 Biological Treatment of Severe Asthma.

Rial MJ, Cañas JA, Rodrigo-Muñoz JM, Valverde-Monge M, Sastre B, Sastre J, Del Pozo V

International journal of molecular sciences. 2021 Mar 30;22(7):3558.

PMID: 33808110

FI: 5,924

IgE-Reactivity Pattern of Tomato Seed and Peel Nonspecific Lipid-Transfer Proteins after in Vitro Gastrointestinal Digestion.

Martín-Pedraza L, Mayorga C, Gomez F, Bueno-Díaz C, Blanca-Lopez N, González M, Martínez-Blanco M, Cuesta-Herranz J, Molina E, Villalba M, Benedé S

Journal of agricultural and food chemistry. Epub 2021 Mar 15. 2021 Mar 24;69(11):3511-3518.

PMID: 33719421

FI: 5,279

Unusual Secretion of Eosinophil Mediators Induced by Benralizumab.

Cañas JA, Valverde-Monge M, Rodríguez-Nieto MJ, González-Mangado N, Sastre J, Del Pozo V

Journal of investigational allergology &clinical immunology. 2021 Mar 2;0.

PMID: 33650971

FI: 7,033

Proteomic profile of extracellular vesicles in anaphylaxis and their role in vascular permeability.

Nuñez-Borque E, Fernandez-Bravo S, Pastor-Vargas C, Alvarez-Llamas G, Gutierrez-Blazquez MD, Alwashali E, Laguna JJ, Dionicio J, Betancor D, Villalobos V, Tome-Amat J, Cuesta-Herranz J, Benito-Martin A, Esteban V

Allergy. Epub 2021 Mar 20. 2021 Jul;76(7):2276-2279.

PMID: 33629411

FI: 13,146

Seroprevalence Study and Cross-Sectional Survey on COVID-19 for a Plan to Reopen the University of Alicante (Spain).

Tuells J, Egoavil CM, Pena Pardo MA, Montagud AC, Montagud E, Caballero P, Zapater P, Puig-Barberá J, Hurtado-Sanchez JA

International journal of environmental research and public health. 2021 Feb 16;18(4):1908.

PMID: 33669412

FI: 3,39

Enhanced anti-inflammatory effects of mesenchymal stromal cells mediated by the transient ectopic expression of CXCR4 and IL10.

Hervás-Salcedo R, Fernández-García M, Hernando-Rodríguez M, Quintana-Bustamante O, Segovia JC, Alvarez-Silva M, García-Arranz M, Minguez P, Del Pozo V, de Alba MR, García-Olmo D, Ayuso C, Lamana ML, Bueren JA, Yañez RM

Stem cell research &therapy. 2021 Feb 12;12(1):124.

PMID: 33579367

FI: 6,832

Where Have All The Nasal Polyposis Gone?

Ortega-Martin L, Betancor D, Barroso B, Valverde-Monge M, Santillan J, Villacampa JM, Sastre J

Journal of investigational allergology &clinical immunology. 2021 Feb 11;0.

PMID: 33574016

FI: 7,033

Daily Clinical Practice in the Management of Chronic Urticaria in Spain: Results of the UCREX Study.

Ferrer Puga M, Silvestre Salvador JF, Bartra Tomas J, Giménez-Arnau A, Labrador-Horrillo M, Miquel-Miquel J, Ortiz de Frutos FJ, Sastre Dominguez J, Valero Santiago A, Terradas-Montana P, Vidal-Jorge M, Jáuregui Presa I

Actas dermo-sifiliograficas. Epub 2021 Jul 20. 2022 Jan;113(1):T4-T14.

PMID: 35249717

FI: 0

De Novo PS1 Mutation (Pro436Gln) in a Very Early-Onset Posterior Variant of Alzheimer's Disease Associated with Spasticity: A Case Report.

Agüero P, Sainz MJ, Téllez R, Lorda I, Ávila A, García-Ribas G, Rodríguez PP, Gómez-Tortosa E

Journal of Alzheimer's disease. 2021;83(3):1011-1016.

PMID: 34366350

FI: 4,472

Vitamin C activates pyruvate dehydrogenase (PDH) targeting the mitochondrial tricarboxylic acid (TCA) cycle in hypoxic KRAS mutant colon cancer.

Cenigaonandia-Campillo A, Serna-Blasco R, Gómez-Ocabo L, Solanes-Casado S, Baños-Herraiz N, Puerto-Nevado LD, Cañas JA, Aceñero MJ, García-Foncillas J, Aguilera Ó

Theranostics. 2021 Jan 25;11(8):3595-3606.

PMID: 33664850

FI: 11,556

Food allergy as an asthma comorbidity in children and adolescents: a practical approach through a real-world study.

Esteban-Gorgojo I, Gorgojo MP, Sastre J, Quirce S

Allergologia et immunopathologia. 2021 Jan 2;49(1):68-78.

PMID: 33528932

FI: 1,667

Serum microRNAs as Tool to Predict Early Response to Benralizumab in Severe Eosinophilic Asthma.

Cañas JA, Valverde-Monge M, Rodrigo-Muñoz JM, Sastre B, Gil-Martínez M, García-Latorre R, Rial MJ, Gómez-Cardeñosa A, Fernández-Nieto M, Pinillos-Robles EJ, Rodríguez-Nieto MJ, González-Mangado N, Sastre J, Pozo VD

Journal of personalized medicine. 2021 Jan 28;11(2):76.

PMID: 33525548

FI: 4,945

Spatial differentiation of metabolism in prostate cancer tissue by MALDI-TOF MSI.

Andersen MK, Høiem TS, Claes BSR, Balluff B, Martin-Lorenzo M, Richardsen E, Krossa S, Bertilsson H, Heeren RMA, Rye MB, Giskeødegård GF, Bathen TF, Tessem MB

Cancer &metabolism. 2021 Jan 29;9(1):9.

PMID: 33514438

FI: 5,469

Isolation and Functional Aspects of Eosinophil-Derived Exosomes.

Cañas JA, Rodrigo-Muñoz JM, Del Pozo V

Methods in molecular biology. 2021;2241:149-159.

PMID: 33486735

FI: 0

Exosomes: A Key Piece in Asthmatic Inflammation.

Cañas JA, Rodrigo-Muñoz JM, Gil-Martínez M, Sastre B, del Pozo V

International journal of molecular sciences. 2021 Jan 19;22(2):963.

PMID: 33478047

FI: 5,924

Clinical Practice Guidelines for Diagnosis and Management of Hypersensitivity Reactions to Quinolones.

Doña I, Blanca-López N, Boteanu C, Cueva-Oliver B, Fernández-Sánchez FJ, Gajate P, García-Avilés MC, García-Núñez I, Lobera T, Moreno E, Rojas P, Rosado A

Journal of investigational allergology &clinical immunology. Epub 2021 Jan 19. 2021 Jul 26;31(4):292-307.

PMID: 33461956

FI: 7,033

Impact of System Biology and Molecular Medicine on the Management of Complex Immune Mediated Respiratory Diseases.

Cárdaba B and Pelaia G (editors)

Frontiers in Immunology and Frontiers in Medicine. 2021

PMID:

FI: 0